You are currently browsing the archives for December, 2009

Xenogeneic Liver Models for Gene Therapy

§ December 31st, 2009 § Filed under Gene therapy Comments Off

Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)

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Nutrition 21 Completes Sale of Direct Response and Retail Businesses to Nature’s Products, Inc. (redOrbit)

§ December 31st, 2009 § Filed under Nutrition Comments Off

PURCHASE, N.Y., Dec. 30 /PRNewswire-FirstCall/ — Nutrition 21, Inc.

Nutrition 21 Completes Sale of Direct Response and Retail Businesses to Nature’s Products, Inc. (PR Newswire via Yahoo! Finance)

§ December 31st, 2009 § Filed under Nutrition Comments Off

Nutrition 21, Inc. , the developer and marketer of nutritional ingredients for the dietary supplement, and functional food and beverage markets announced today that it has sold substantially all of the assets of its direct response and retail businesses to Nature’s Products, Inc., based in Sunrise, Florida.

Endo to Present at J.P. Morgan 28th Annual Healthcare Conference (redOrbit)

§ December 31st, 2009 § Filed under Endocrinology Comments Off

CHADDS FORD, Pa., Dec. 30 /PRNewswire-FirstCall/ — Endo Pharmaceuticals (Nasdaq: ENDP) today announced that it will present at the J.P. Morgan 28th Annual Healthcare Conference on Wednesday, Jan. 13, 2010, at 10:00 a.m. PST.

Fifth Annual World Massage Festival Brings Industry Leaders to Berea, Kentucky

§ December 31st, 2009 § Filed under HCG Therapy Comments Off

Berea College, in Berea, Kentucky, will host the Fifth Annual World Massage Festival and Massage Therapy Hall of Fame, June 17-21, 2010, welcoming therapists from around the world to choose from 56 continuing education workshops taught by 42 leaders of the massage profession, share their insights, honor those who forged the industry and enjoy a weekend of learning, networking and most of all, fun! (PRWeb Dec 30, 2009)


Read the full story at http://www.prweb.com/releases/massage/festival/prweb3388204.htm

Firefighters, police OK bonus delay (The Cincinnati Enquirer)

§ December 31st, 2009 § Filed under Longevity, Longevity Medicine Comments Off

Cincinnati firefighters and police officers have agreed to let the city pay their longevity bonuses for next year in 2011.

Does using anti-wrinkle cream at a young age prevent or cause wrinkles?

§ December 31st, 2009 § Filed under Anti-Aging Medicine Comments Off

I have heard people saying that using anti wrinkle cream when you’re young (like teens or twenties) prevents wrinkles for the future. I have heard other people say that it can actually cause them or that it does no good at all (something about the skin already having enough collagen..?)
Which…

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Adeno-Associated Virus Mediated Gene Therapy in Ischemic Stroke

§ December 31st, 2009 § Filed under Gene therapy Comments Off

Gene therapy offers a novel approach for the treatment of experimental stroke. The adeno-associated virus (AAV) mediated vascular endothelial growth factor (VEGF) gene transfer into the ischemic brain is described in detail in this chapter. Other methods are also illustrated here, including the generation of mouse middle cerebral artery occlusion (MCAO) model, injection of viral vector into mouse brain, and standard assays for determining the successes of brain ischemia and gene transfer. (Source: Springer protocols feed by Neuroscience)

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Use of Mesenchymal Stem Cells for Gene Delivery to Intracranial Glioma

§ December 31st, 2009 § Filed under Gene therapy Comments Off

Virus-mediated gene therapies against brain tumors have been limited by the difficulty in tracking glioma cells infiltrating the brain parenchyma. Mesenchymal stem cells (MSCs) are particularly attractive cells for clinical use in cell-based therapies because they have tumor-targeting properties, can be easily isolated and expanded to the numbers required for use, and can be genetically manipulated with viral vectors. In addition, most of the replication-deficient adenoviral vectors that have been used to transduce MSCs are based on human Ad serotype 5 (Ad5). However, transduction of MSCs by conventional Ad5 vectors is inefficient, even when very high multiplicities of infection are used because MSCs do not express the cellular coxsackie-adenovirus receptor. This chapter describes in detai…

An Overview of Drug Delivery to the CNS

§ December 31st, 2009 § Filed under Gene therapy Comments Off

Limitation of drug delivery to the central nervous system (CNS) is a major problem in development of successful treatment of CNS disorders. Concepts of blood–brain barrier (BBB), its role in transport of various substances from the blood to the brain, as well as strategies to deliver drugs across the BBB have evolved over the past century. This chapter is an overview of the challenges and various approaches to drug delivery in CNS disorders as an introduction to other chapters, which deal with laboratory and clinical methods of CNS drug delivery. A classification of current strategies for drug delivery across the BBB is presented. These include novel formulations of drugs such as nanoparticles and strategies to cross the BBB. Drugs can be introduced directly into the CNS and various …

Intraparenchymal Delivery and Its Discontents

§ December 31st, 2009 § Filed under Gene therapy Comments Off

In the treatment of central nervous system diseases, therapeutic particles need to breach the blood–brain barrier (BBB) to reach their intended target, and it has long been known that this is a difficult barrier to breach. The barrier is both passive with tight junctions hindering passage of even rather small molecules, as well as active with transporters that can pump select molecules back into the bloodstream. The diseases include both those where this barrier has been compromised such as brain tumors, hemorrhagic stroke, and neurotrauma; as well as neurodegenerative disorders where the compromise is substantially less and often unnoticeable. In addition to the pharmaceutical solution which involves design of small molecules that may be administered orally or at least systemically,…

The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses [Biochemistry]

§ December 31st, 2009 § Filed under Gene therapy Comments Off

Baculoviruses are ubiquitous insect viruses well known for their use as bioinsecticides, gene therapy vectors, and protein expression systems. Overexpression… (Source: Proceedings of the National Academy of Sciences)

Navy blue uniforms for football are abhorrent (The Daily Tar Heel)

§ December 31st, 2009 § Filed under Testosterone Comments Off

Those navy blue football uniforms suck. There is no other way to say it. They do not imbue more testosterone; rather, they confuse the public and insult every true Tar Heel.

Aging, inflammation and cancer

§ December 31st, 2009 § Filed under Stem Cell Therapy Comments Off

Aging and inflammation: etiological culprits of cancer by Aamir Ahmad and 5 co-authors, including Fazlul H Sarkar, Curr Aging Sci 2009(Dec); 2(3): 174-86 [PubMed Citation][Full text in PMC]. Excerpt from the full text:

In the context of cancer, like normal tissues, various cancerous tissues also harbor a minor population of cells with enormous self-renewal and tumor-initiating capacity. Such cells are referred to as tumor-initiating cells or cancer stem cells, which offer an attractive target for cancer therapy [136] provided that normal stem cells are spared from the side effects of therapy. A number of molecular events that mark stem cell aging also occur in tumors in the elderly [134] and, as such, play important roles in the processes of cancer and aging, suggesting that these two processes are intertwined.

Comment: The full text of this article is available via PubMed Central (PMC). However, if accessed at the website of Current Aging Science (a journal of Bentham Science Publishers), the full text can only be purchased, and prior registration is required.For some background information about this publisher, see an entry in the French version of Wikipedia [Google translation into English]. (This entry is currently not available in the English version of Wikipedia).

How do U.S. airline meals rank for nutrition? (San Jose Mercury News)

§ December 30th, 2009 § Filed under Nutrition Comments Off

Most airline food has fewer calories today compared to 10 years ago, but nutrition advocate Charles Stuart Platkin says airlines should offer better options.

New Reference Book from Toledo Author Offers a Variety of Facts About Snakes

§ December 30th, 2009 § Filed under Endocrinology Comments Off

This comprehensive new guide has been released by Dorrance Publishing Co., Inc. (PRWeb Dec 30, 2009)


Read the full story at http://www.prweb.com/releases/2009/12/prweb3387514.htm

Local Professional Elected to Help Shape Senior Policy

§ December 30th, 2009 § Filed under Endocrinology Comments Off

San Francisco Bay Area native and business owner, Linda Fodrini-Johnson, MA, MFT, CMC, has been elected the 2010 President of the National Association of Professional Geriatric Care Managers, the premier geriatric care management organization in the country. Fodrini-Johnson will be serving during a critical point for the senior care industry as the Baby Boomers begin to retire. (PRWeb Dec 30, 2009)


Read the full story at http://www.prweb.com/releases/2009/12/prweb3392404.htm

Study Finds the Lack of Flowers at Funerals May Hinder Grieving Process

§ December 30th, 2009 § Filed under Endocrinology Comments Off

Recent research indicates that sympathy flowers may not only brighten and warm a funeral or memorial service setting, but also have a positive impact on the emotional well being of the bereaved. The phrase "In Lieu of Flowers" is now considered a major barrier to the healing process. Clay Atchison has archived this study, and related information, on the Web site, inlieuofflowers.info, to support people in making the right decision regarding funeral flowers. (PRWeb Dec 30, 2009)


Read the full story at http://www.prweb.com/releases/2009/12/prweb3393244.htm

Amazing New Drug-Free Pain Treatment Available in Shelby Township, Michigan that Erases Pain in 5 Minutes

§ December 30th, 2009 § Filed under Endocrinology Comments Off

Neck and back pain sufferers have finally found relief with the Active Therapeutic Movement (ATM) treatment and Dr. Karl R.O.S. Johnson, D.C. This breakthrough treatment can have the worst sufferers pain free in minutes. (PRWeb Dec 30, 2009)


Read the full story at http://www.prweb.com/releases/2009/12/prweb3389254.htm

Learn to Fly in 2010 with SportFlyingGuide.com

§ December 30th, 2009 § Filed under Endocrinology Comments Off

Private aviation is less expensive than ever, luring travelers into discovering the enjoyment and safety of flying their own airplanes. (PRWeb Dec 30, 2009)


Read the full story at http://www.prweb.com/releases/2009/12/prweb3391604.htm

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