Chemotherapy is a major first line defense against breast cancer. However a patient's response is often variable and unpredictable. A study published in BioMed Central's open access journal BMC Medical Genomics shows that 'gene expression signatures' for TOP2A and ?-tubulin can be used to predict the outcome of chemotherapy.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=genetic+therapy&eo=UTF-8
Read the Rest...MELBOURNE, AUSTRALIA– – In compliance with ASX Continuing Disclosure Rules, Genetic Technologies Limited is pleased to report that it has executed a Settlement and License Agreement with GeneSeek Inc. …Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=genetic+therapy&eo=UTF-8
Read the Rest...( University of North Carolina School of Medicine ) A UNC-led team of scientists has shown for the first time that lung cancer molecular subtypes correlate with distinct genetic alterations and with patient response to therapy. These findings in pre-clinical models and patient tumor samples build on their previous report of three molecular subtypes of [...]
Read the Rest...Testing could prove an effective remedy to a widespread problem. But there may be hidden hazards to our privacy Three years ago, Theo Dingermann, a professor of pharmaceutical biology at Goethe University in Frankfurt, sent a glob of spit to the United States. For $200 a company there sequenced part of his genome using DNA from his [...]
Read the Rest...( Johns Hopkins Medical Institutions ) A team of researchers from Johns Hopkins University and the National Human Genome Research Institute has evaluated the whole genomic sequence of stem cells derived from human bone marrow cells — so-called induced pluripotent stem cells — and found that relatively few genetic changes occur during stem cell conversion [...]
Read the Rest...Huntington's disease (HD) is a hereditary neurodegenerative disorder that causes involuntary movements, emotional disturbances and diminished cognitive abilities.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=genetic+therapy&eo=UTF-8
Read the Rest...Treatment of chronic hepatitis C (CHC) is a prototype for personalized medicine. Combination therapy with peginterferon alfa plus ribavirin was the standard of care for more than a decade.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=genetic+therapy&eo=UTF-8
Read the Rest...Five years ago, a one-year-old boy named Connor was brought in for a second opinion. He had gone to a fine pediatrician on the Main Line who knew that something was very wrong, but did not know exactly what.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=genetic+therapy&eo=UTF-8
Read the Rest...Today’s post is a repost from October 2010. I’ve got some major stuff cooking in the lab right now and I need all of my brain power for it. Enjoy the repost and I shall return! Reader David sent me this paper the other day, and asked if I could blog about it. I said [...]
Read the Rest...For a quarter of a century, gene therapy has been stymied, largely because the patient's immune system attacks the treatment as a suspected rogue – or because it actually does turn rogue.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=gene+therapy&eo=UTF-8
Read the Rest...HIV patients given gene therapy more than a decade ago are healthy and the altered DNA they received remains stable in their bodies, according to a study that scientists say proves the treatment may safely be tested as a way to attack other illnesses.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=gene+therapy&eo=UTF-8
Read the Rest...Regenerating sensory hair cells could form the basis for treating age- or trauma-related hearing loss. One way to do this could be with gene therapy that drives new sensory hair cells to grow. Researchers have shown that introducing a gene called Atoh1 into the cochleae of young mice can induce the formation of extra sensory [...]
Read the Rest...Conclusions: The present study demonstrated for the first time the potential antitumor activity of IFN-alpha combined with the oncolytic adenovirus SG600-IL-24 in HCC both in vitro and in vivo, and suggests its further development as a potential candidate for HCC cancer gene therapy. (Source: Molecular Cancer)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Read the Rest...Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Read the Rest...Gene therapy protects body while leaving cancer cells vulnerable (Source: ScienceNOW)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Read the Rest...The immunodeficiency disorder Wiskott-Aldrich syndrome (WAS) leads to life-threatening hematopoietic cell dysfunction. We used WAS protein (WASp)–deficient mice to analyze the in vivo efficacy of lentiviral (LV) vectors using either a viral-derived promoter, MND, or the human proximal WAS promoter (WS1.6) for human WASp expression. Transplantation of stem cells transduced with MND-huWASp LV resulted in [...]
Read the Rest...Conclusions The new NGS approach delivers a step change in the diagnosis of inherited eye disease, provides precise diagnostic information and extends the possibility of targeted treatments including gene therapy. The approach represents an exemplar that illustrates the opportunity that NGS provides for broadening the availability of genetic testing. The technology will be applied to [...]
Read the Rest...Title: Study: Gene Therapy for HIV Safe, But Effectiveness Still UnclearCategory: Health NewsCreated: 5/2/2012 4:05:00 PMLast Editorial Review: 5/3/2012 12:00:00 AM (Source: MedicineNet HIV General)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Read the Rest...(MedPage Today) — A gene therapy approach to HIV treatment is long-lasting and safe, researchers reported. (Source: MedPage Today Infectious Disease) MedWorm Sponsor Message: Please have a look at this new site driven by MedWorm: The Breast Cancer Daily Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Read the Rest...Authors: H Shen, T Sun & M Ferrari (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml
Read the Rest...