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Global Gene Therapy Industry

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

NEW YORK, April 16, 2012 /PRNewswire/ — Reportlinker.com announces that a new market research report is available in its catalogue: Global Gene Therapy Industry http://www.reportlinker.com/p098244/Global-Gene-Therapy-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=BiologicaThis …Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=gene+therapy&eo=UTF-8

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Innovative Methods for Improving Measures of the Personal Environment

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

A popular adage in thinking about disease risk states that “your genes may load the gun, but your environment pulls the trigger.” Nearly a decade following the completion of the Human Genome Project, it is clear that genetic variation is an important determinant of disease risk. Genome Wide Association Studies (GWAS) have identified numerous variants [...]

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Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-?

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

Potent systemic therapy of multiple myeloma utilizing oncolytic vesicular stomatitis virus coding for interferon-β Cancer Gene Therapy advance online publication, April 20, 2012. doi:10.1038/cgt.2012.14 Authors: S Naik, R Nace, G N Barber & S J Russell (Source: Cancer Gene Therapy) MedWorm Sponsor Message: Please have a look at this new site driven by MedWorm: The [...]

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Treatment of adult MPSI mouse brains with IDUA-expressing mesenchymal stem cells decreases GAG deposition and improves exploratory behavior

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

Conclusions: These data show that gene therapy, via the direct injection of IDUA-expressing MSCs into the brain, is an effective way to treat neurodegeneration in MPSI mice. (Source: Genetic Vaccines and Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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Direct conversion in the heart: a simple twist of fate

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

This study hints that a gene therapy approach for in-situ reprogramming may provide an alternative for generating new cardiomyocytes within failing hearts. (Source: The EMBO Journal AOP)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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[World Report] Promising new era dawns for cystic fibrosis treatment

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

The recent approval of a new drug and the start of a phase 2 gene therapy trial are creating excitement about future treatment possibilities for people with cystic fibrosis. Zöe Corbyn reports. (Source: LANCET)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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British Society for Gene Therapy 2012; March 9, 2012; UCL Institute of Child Health, London

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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Lab Notes: Skin Cancer Spread Tied to Gene

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

(MedPage Today) — Targeted gene therapy might help stop the spread of melanoma metastases, in this week’s Lab Notes. Also, how can yeast help with depression and a quick fix for cocaine OD. (Source: MedPage Today Cardiovascular) MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up [...]

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Treatment of a Solid Tumor Using Engineered Drug-Resistant Immunocompetent Cells and Cytotoxic Chemotherapy

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

Human Gene Therapy , Vol. 0, No. 0. (Source: Human Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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Btk levels set the threshold for B-cell activation and negative selection of autoreactive B cells in mice

§ April 22nd, 2012 § Filed under Gene therapy Comments Off

On antigen binding by the B-cell receptor (BCR), B cells up-regulate protein expression of the key downstream signaling molecule Bruton tyrosine kinase (Btk), but the effects of Btk up-regulation on B-cell function are unknown. Here, we show that transgenic mice overexpressing Btk specifically in B cells spontaneously formed germinal centers and manifested increased plasma cell [...]

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Gene therapy helps woman to write

§ April 15th, 2012 § Filed under Gene therapy Comments Off

A British woman stricken with Parkinson's disease can write for the first time in 15 years after receiving gene therapy.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=gene+therapy&eo=UTF-8

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Video: Gene therapy reverses Parkinson's symptoms: study

§ April 15th, 2012 § Filed under Gene therapy Comments Off

A new British study has discovered a potentially groundbreaking treatment for Parkinson's disease. Neurosurgeon Dr. Michael Kaplitt speaks to the "CBS This Morning" co-hosts about how gene therapy can reverse Parkinson's symptoms.Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=gene+therapy&eo=UTF-8

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Gene Therapy Restores Sight to Three Patients

§ April 15th, 2012 § Filed under Gene therapy Comments Off

After several years of setbacks, gene therapy is once again yielding promising results. One area in which it is proving its potential is in restoring vision to patients who have been losing it since birth. [More]Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=gene+therapy&eo=UTF-8

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Genetic Technologies' Subsidiary Update

§ April 15th, 2012 § Filed under Gene therapy Comments Off

MELBOURNE, AUSTRALIA– – Genetic Technologies Limited is pleased to announce that ImmunAid Pty. Ltd., its privately held subsidiary, has successfully obtained A$1 million in a private placement from US, …Source:http://news.search.yahoo.com/news/rss?ei=UTF-8&p=genetic+therapy&eo=UTF-8

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Combining transfer of TTF-1 and Pax-8 gene: a potential strategy to promote radioiodine therapy of thyroid carcinoma

§ April 15th, 2012 § Filed under Gene therapy Comments Off

Authors: D Mu, R Huang, S Li, X Ma, C Lou & A Kuang (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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Human amniotic fluid-derived stem cells expressing cytosine deaminase and thymidine kinase inhibits the growth of breast cancer cells in cellular and xenograft mouse models

§ April 15th, 2012 § Filed under Gene therapy Comments Off

Authors: N-H Kang, K-A Hwang, B-R Yi, H J Lee, E-B Jeung, S U Kim & K-C Choi (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer

§ April 15th, 2012 § Filed under Gene therapy Comments Off

Phase 1/2a, dose-escalation, safety, pharmacokinetic and preliminary efficacy study of intratumoral administration of BC-819 in patients with unresectable pancreatic cancer Cancer Gene Therapy advance online publication, April 13, 2012. doi:10.1038/cgt.2012.10 Authors: N Hanna, P Ohana, F M Konikoff, G Leichtmann, A Hubert, L Appelbaum, Y Kopelman, A Czerniak & A Hochberg (Source: Cancer Gene Therapy)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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The radiation dose-regulated AND gate genetic circuit, a novel targeted and real-time monitoring strategy for cancer gene therapy

§ April 15th, 2012 § Filed under Gene therapy Comments Off

Authors: M Ding, E Zhang, R He, X Wang, R Li, W Wang & Q Yi (Source: Cancer Gene Therapy) MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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Legal expert explores risks, rewards of using stem cell products

§ April 15th, 2012 § Filed under Gene therapy Comments Off

The brave new world of stem cell research dangles the exciting potential for a host of leading-edge treatments that may one day help cure debilitating diseases such as Alzheimer’s, Parkinson’s and other maladies that today cannot be treated with modern medicine.   However, not much thought has been given to how those products might be [...]

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Efficient transfection of MG?63 osteoblasts using magnetic nanoparticles and oscillating magnetic fields

§ April 15th, 2012 § Filed under Gene therapy Comments Off

Conclusion: Non?viral transfection using MNPs and the magnefect?nano system can be used to transfect MG?63 cells and assist reporter gene delivery on a single cell basis, highlighting the wide potential of nanomagnetic gene transfection in gene therapy. Copyright © 2012 John Wiley & Sons, Ltd. (Source: Journal of Tissue Engineering and Regenerative Medicine)Source:http://www.medworm.com/rss/medicalfeeds/therapies/Gene-Therapy.xml

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