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What to Know About Wildfire Smoke and COVID-19 – UCSF News Services

§ August 28th, 2020 § Filed under Nano Medicine Comments Off on What to Know About Wildfire Smoke and COVID-19 – UCSF News Services

Smoke rises from a wildfire burning in the Santa Cruz Mountains in California. Getty Images photo

Wildfires are again raging in California, but this years season began in a perfect storm of smoke from the blazes, a scorching heat wave, and the ongoing COVID-19 pandemic.

During a typical wildfire season, hospitals see more people coming in for respiratory issues, said Stephanie Christenson, MD, assistant professor of pulmonology at UC San Francisco. The worry this year is that the smoke from wildfires could increase the severity of COVID-19 symptoms.

Though there have yet to be studies looking specifically at the effect of wildfire smoke on COVID-19, there is preliminary research linking air pollution to increased COVID-19 susceptibility, severity and death, said Christenson.

With wildfire smoke, and air pollution generally, the most concerning are the microscopic particles that are about 2.5 microns in size (about 30 times smaller than the width of a human hair), which can be inhaled deep into the lungs, said John Balmes, MD, professor of medicine. There, these tiny toxins can injure the lining of the lungs, in a process known as oxidative stress, and cause airway inflammation.

People with certain chronic respiratory conditions, such as asthma, already have airway inflammation, and the added inflammation from wildfire smoke would be particularly harmful, said Balmes. There is no question that wildfire smoke can exacerbate these pre-existing conditions.

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Research also has shown that wildfire smoke raises the risk of lower respiratory tract infections such as acute bronchitis and pneumonia, by impairing the immune response, said Balmes. The immune cells, known as alveolar macrophages, that patrol our lower lungs are adept at engulfing and digesting foreign particles, such as bacteria. But when these macrophages engulf the combustion particles in wildfire smoke, they cannot digest them, and essentially are disabled from performing their role in the immune response.

Wildfire smoke, like COVID-19, can affect more than the lungs. A study from the 2015 wildfire season found that emergency room visits in areas most affected by smoke increased not only for respiratory complaints, but also cardiovascular and neurological complaints, such as stroke, said Jahan Fahimi, MD, PhD, an emergency care physician.

My advice to the public is that people should be sheltering in place as much as possible, said Balmes. Stay home with windows closed, ventilation turned to recirculate, and if possible, have a clean air room with a HEPA air purifying appliance.

To avoid COVID-19 exposure, its safest to stay home with the people you already live with, added Fahimi.

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As for masks, Balmes noted that N95 masks fitted tightly over the face offer the best protection against wildfire smoke particles, but that N95 masks with exhalation valves do not provide COVID-19 protection. He recommends covering the valve with tape or wearing a surgical mask over the N95.

Because N95 masks (without valves) should be reserved for health care workers treating COVID-19, experts do not suggest buying new N95 masks unless you need to be outside for an extended period of time.

Fahimi drew a parallel between wildfire smoke and the coronavirus that in both cases, the duration and dose of exposure determines risk. If youre only going to be out for 10 to 15 minutes, even no mask is fine for a short duration, he said. But people working outdoors, thats when you want a mask.

Surgical masks are more readily available and will provide some protection against wildfire smoke, said Balmes. Cloth masks likely provide little protection against PM2.5 particles, but are still essential for COVID-19 protection.

If you cant get a surgical or a N95 mask, wear a cloth mask because the most important thing is to protect others from the virus, said Balmes.

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Women experience adverse drug reactions nearly twice as frequently as men. Here’s why. – Big Think

§ August 28th, 2020 § Filed under Nano Medicine Comments Off on Women experience adverse drug reactions nearly twice as frequently as men. Here’s why. – Big Think

But soon it will take place on the deep seabed, which belongs to everyone, according to international law. Seabed mining for valuable materials like copper, zinc and lithium already takes place within countries' marine territories. As soon as 2025, larger projects could start in international waters areas more than 200 nautical miles from shore, beyond national jurisdictions. We study ocean policy, marine resource management, international ocean governance and environmental regimes, and are researching political processes that govern deep seabed mining. Our main interests are the environmental impacts of seabed mining, ways of sharing marine resources equitably and the use of tools like marine protected areas to protect rare, vulnerable and fragile species and ecosystems. Today countries are working together on rules for seabed mining. In our opinion, there is still time to develop a framework that will enable nations to share resources and prevent permanent damage to the deep sea. But that will happen only if countries are willing to cooperate and make sacrifices for the greater good.

An old treaty with a new purpose

Countries regulate seabed mining within their marine territories. Farther out, in areas beyond national jurisdiction, they cooperate through the Law of the Sea Convention, which has been ratified by 167 countries and the European Union, but not the U.S.

The treaty created the International Seabed Authority, headquartered in Jamaica, to manage seabed mining in international waters. This organization's workload is about to balloon.

Under the treaty, activities conducted in areas beyond national jurisdiction must be for "the benefit of mankind as a whole." These benefits could include economic profit, scientific research findings, specialized technology and recovery of historical objects. The convention calls on governments to share them fairly, with special attention to developing countries' interests and needs.

The United States was involved in negotiating the convention and signed it but has not ratified it, due to concerns that it puts too many limits on exploitation of deep sea resources. As a result, the U.S. is not bound by the treaty, although it follows most of its rules independently. Recent administrations, including those of Presidents Bill Clinton, George W. Bush and Barack Obama, sought to ratify the treaty, but failed to muster a two-thirds majority in the Senate to support it.

Map    of world oceans showing where major metal deposits lie.Locations of three main types of marine mineral deposits: polymetallic nodules (blue); polymetallic or seafloor massive sulfides (orange); and cobalt-rich ferromanganese crusts (yellow). Miller et al., 2018, https://doi.org/10.3389/fmars.2017.00418, CC BY

Powering digital devices

Scientists and industry leaders have known that there are valuable minerals on the seafloor for over a century, but it hasn't been technologically or economically feasible to go after them until the past decade. Widespread growth of battery-driven technologies such as smartphones, computers, wind turbines and solar panels is changing this calculation as the world runs low on land-based deposits of copper, nickel, aluminum, manganese, zinc, lithium and cobalt.

These minerals are found in potato-shaped "nodules" on the seafloor, as well as in and around hydrothermal vents, seamounts and midocean ridges. Energy companies and their governments are also interested in extracting methane hydrates frozen deposits of natural gas on the seafloor.

Scientists still have a lot to learn about these habitats and the species that live there. Research expeditions are continually discovering new species in deep-sea habitats.

Korea and China seek the most contracts

Mining the deep ocean requires permission from the International Seabed Authority. Exploration contracts provide the right to explore a specific part of the seabed for 15 years. As of mid-2020, 30 mining groups have signed exploration contracts, including governments, public-private partnerships, international consortiums and private multinational companies.

Two entities hold the most exploration contracts (three each): the government of Korea and the China Ocean Mineral Resources R&D Association, a state-owned company. Since the U.S. is not a member of the Law of the Sea treaty, it cannot apply for contracts. But U.S. companies are investing in others' projects. For example, the American defense company Lockheed Martin owns UK Seabed Resources, which holds two exploration contracts.

Once an exploration contract expires, as several have since 2015, mining companies must broker an exploitation contract with the International Seabed Authority to allow for commercial-scale extraction. The agency is working on rules for mining, which will shape individual contracts.

Unknown ecological impacts

Deep-sea mining technology is still in development but will probably include vacuuming nodules from the seafloor. Scraping and vacuuming the seafloor can destroy habitats and release plumes of sediment that blanket or choke filter-feeding species on the seafloor and fish swimming in the water column.

Mining also introduces noise, vibration and light pollution in a zone that normally is silent, still and dark. And depending on the type of mining taking place, it could lead to chemical leaks and spills.

Many deep-sea species are unique and found nowhere else. We agree with the scientific community and environmental advocates that it is critically important to analyze the potential effects of seabed mining thoroughly. Studies also should inform decision-makers about how to manage the process.

This is a key moment for the International Seabed Authority. It is currently writing the rules for environmental protection but doesn't have enough information about the deep ocean and the impacts of mining. Today the agency relies on seabed mining companies to report on and monitor themselves, and on academic researchers to provide baseline ecosystem data.

We believe that national governments acting through the International Seabed Authority should require more scientific research and monitoring, and better support the agency's efforts to analyze and act on that information. Such action would make it possible to slow the process down and make better decisions about when, where and how to mine the deep seabed.

Balancing risks and benefits

The race for deep-sea minerals is imminent. There are compelling arguments for mining the seabed, such as supporting the transition to renewable energy, which some companies assert will be a net gain for the environment. But balancing benefits and impacts will require proactive and thorough study before the industry takes off.

We also believe that the U.S. should ratify the Law of the Sea treaty so that it can help to lead on this issue. The oceans provide humans with food and oxygen and regulate Earth's climate. Choices being made now could affect them far into the future in ways that aren't yet understood.

Dr. Rachel Tiller, Senior Research Scientist with SINTEF Ocean, Norway, contributed to this article.The Conversation

Elizabeth M. De Santo, Associate Professor of Environmental Studies, Franklin & Marshall College; Elizabeth Mendenhall, Assistant Professor of Marine Affairs and Political Science, University of Rhode Island, and Elizabeth Nyman, Assistant Professor of Maritime Policy, Texas A&M University

This article is republished from The Conversation under a Creative Commons license. Read the original article.

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Trends in the Ready To Use Regenerative Medicine Products Market 2020-2021 – Owned

§ August 28th, 2020 § Filed under Nano Medicine Comments Off on Trends in the Ready To Use Regenerative Medicine Products Market 2020-2021 – Owned

The Regenerative Medicine Products market research encompasses an exhaustive analysis of the market outlook, framework, and socio-economic impacts. The report covers the accurate investigation of the market size, share, product footprint, revenue, and progress rate. Driven by primary and secondary researches, the Regenerative Medicine Products market study offers reliable and authentic projections regarding the technical jargon.

All the players running in the global Regenerative Medicine Products market are elaborated thoroughly in the Regenerative Medicine Products market report on the basis of proprietary technologies, distribution channels, industrial penetration, manufacturing processes, and revenue. In addition, the report examines R&D developments, legal policies, and strategies defining the competitiveness of the Regenerative Medicine Products market players.

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Market Segment Analysis The research report includes specific segments by Type and by Application. This study provides information about the sales and revenue during the historic and forecasted period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type, the Regenerative Medicine Products market is segmented into Cell Therapy Tissue Engineering Biomaterial Others

Segment by Application Dermatology Cardiovascular CNS Orthopedic Others

Global Regenerative Medicine Products Market: Regional Analysis The Regenerative Medicine Products market is analysed and market size information is provided by regions (countries). The report includes country-wise and region-wise market size for the period 2015-2026. It also includes market size and forecast by Type and by Application segment in terms of sales and revenue for the period 2015-2026. The key regions covered in the Regenerative Medicine Products market report are: North America U.S. Canada Europe Germany France U.K. Italy Russia Asia-Pacific China Japan South Korea India Australia Taiwan Indonesia Thailand Malaysia Philippines Vietnam Latin America Mexico Brazil Argentina Middle East & Africa Turkey Saudi Arabia U.A.E Global Regenerative Medicine Products Market: Competitive Analysis This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and sales by manufacturers during the forecast period of 2015 to 2019. The major players in global Regenerative Medicine Products market include: Acelity DePuy Synthes Medtronic ZimmerBiomet Stryker MiMedx Group Organogenesis UniQure Cellular Dynamics International Osiris Therapeutics Vcanbio Gamida Cell Golden Meditech Cytori Therapeutics Celgene Vericel Corporation Guanhao Biotech Mesoblast Stemcell Technologes Bellicum Pharmaceuticals

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Objectives of the Regenerative Medicine Products Market Study:

The Regenerative Medicine Products market research focuses on the market structure and various factors (positive and negative) affecting the growth of the market. The study encloses a precise evaluation of the Regenerative Medicine Products market, including growth rate, current scenario, and volume inflation prospects, on the basis of DROT and Porters Five Forces analyses. In addition, the Regenerative Medicine Products market study provides reliable and authentic projections regarding the technical jargon.

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X-Ray Contrast Agents Market 2020 Trends, Size, Segments, Emerging Technologies and Industry Growth by Forecast to 2025 – Scientect

§ August 28th, 2020 § Filed under Nano Medicine Comments Off on X-Ray Contrast Agents Market 2020 Trends, Size, Segments, Emerging Technologies and Industry Growth by Forecast to 2025 – Scientect

In 2018, the market size of X-Ray Contrast Agents Market is million US$ and it will reach million US$ in 2025, growing at a CAGR of from 2018; while in China, the market size is valued at xx million US$ and will increase to xx million US$ in 2025, with a CAGR of xx% during forecast period.

In this report, 2018 has been considered as the base year and 2018 to 2025 as the forecast period to estimate the market size for X-Ray Contrast Agents .

This report studies the global market size of X-Ray Contrast Agents , especially focuses on the key regions like United States, European Union, China, and other regions (Japan, Korea, India and Southeast Asia).

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This study presents the X-Ray Contrast Agents Market production, revenue, market share and growth rate for each key company, and also covers the breakdown data (production, consumption, revenue and market share) by regions, type and applications. X-Ray Contrast Agents history breakdown data from 2014 to 2018, and forecast to 2025.

For top companies in United States, European Union and China, this report investigates and analyzes the production, value, price, market share and growth rate for the top manufacturers, key data from 2014 to 2018.

In global X-Ray Contrast Agents market, the following companies are covered:

Market Segment Analysis The research report includes specific segments by Type and by Application. This study provides information about the sales and revenue during the historic and forecasted period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type, the X-Ray Contrast Agents market is segmented into Medical Barium Sulfate Iodine

Segment by Application Hospitals Clinics Other

Global X-Ray Contrast Agents Market: Regional Analysis The X-Ray Contrast Agents market is analysed and market size information is provided by regions (countries). The report includes country-wise and region-wise market size for the period 2015-2026. It also includes market size and forecast by Type and by Application segment in terms of sales and revenue for the period 2015-2026. The key regions covered in the X-Ray Contrast Agents market report are: North America U.S. Canada Europe Germany France U.K. Italy Russia Asia-Pacific China Japan South Korea India Australia Taiwan Indonesia Thailand Malaysia Philippines Vietnam Latin America Mexico Brazil Argentina Middle East & Africa Turkey Saudi Arabia U.A.E Global X-Ray Contrast Agents Market: Competitive Analysis This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and sales by manufacturers during the forecast period of 2015 to 2019. The major players in global X-Ray Contrast Agents market include: Lantheus Medical Imaging Bracco SpA GE Healthcare Daiichi Sankyo Company Bayer Guerbet Group Hengrui Medicine BeiLu Pharmaceutical

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The content of the study subjects, includes a total of 15 chapters:

Chapter 1, to describe X-Ray Contrast Agents product scope, market overview, market opportunities, market driving force and market risks.

Chapter 2, to profile the top manufacturers of X-Ray Contrast Agents , with price, sales, revenue and global market share of X-Ray Contrast Agents in 2017 and 2018.

Chapter 3, the X-Ray Contrast Agents competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast.

Chapter 4, the X-Ray Contrast Agents breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2014 to 2018.

Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2014 to 2018.

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Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2014 to 2018.

Chapter 12, X-Ray Contrast Agents market forecast, by regions, type and application, with sales and revenue, from 2018 to 2024.

Chapter 13, 14 and 15, to describe X-Ray Contrast Agents sales channel, distributors, customers, research findings and conclusion, appendix and data source.

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X-Ray Contrast Agents Market 2020 Trends, Size, Segments, Emerging Technologies and Industry Growth by Forecast to 2025 - Scientect

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COVID-19 Update: Global Payment Gateways Market is Expected to Grow at a Healthy CAGR with Top players: PayPal, Amazon Payments, Authorize.net,…

§ August 28th, 2020 § Filed under Nano Medicine Comments Off on COVID-19 Update: Global Payment Gateways Market is Expected to Grow at a Healthy CAGR with Top players: PayPal, Amazon Payments, Authorize.net,…

Los Angles United States, August 2020: The Payment Gateways Market steadily escalating demand due to improving purchasing power is projected to bode well for the global market. WMRlatest publication, Titled Payment Gateways Market Research Report 2020, offers an insightful take on the drivers and restraints present in the market. It assesses the historical data pertaining to the Payment Gateways market and compares it to the current market trends to give the readers a detailed analysis of the trajectory of the market. A team subject-matter experts have provided the readers a qualitative and quantitative data about the market and the various elements associated with it.

The new report offers a powerful combination of latest, in-depth research studies on the Payment Gateways market. The authors of the report are highly experienced analysts and possess deep market knowledge. Some of the key players operating in this Report are:Stripe, PayPal, Amazon Payments, Authorize.net, WorldPay, Adyen, CCBill, 2Checkout, First Data, SecurePay, PayU, MOLPay, Paymill, GMO, Alipay, Tenpay, Ping++

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Payment Gateways Players/Suppliers Profiles and Sales Data:Company, Company Basic Information, Manufacturing Base and Competitors, Product Category, Application and Specification with Sales, Revenue, Price and Gross Margin, Main Business/Business Overview.

The Best part of this report is, this analyses the current state where all are fighting with the covid-19, The report also provides the market impact and new opportunities created due to the Covid19 catastrophe.

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Key Benefits for Stakeholders

The study provides an in-depth analysis of the Payment Gateways market size along with the current trends and future estimations to elucidate the imminent investment pockets. Information about key drivers, restraints, and opportunities and their impact analysis on the market size is provided. Porters five forces analysis illustrates the potency of buyers and suppliers operating in the portable gaming industry. The quantitative analysis of the Payment Gateways industry from 2020 to 2026 is provided to determine the Payment Gateways market potential.

The research report is broken down into chapters, which are introduced by the executive summary. Its the introductory part of the chapter, which includes details about global market figures, both historical and estimates. The executive summary also provides a brief about the segments and the reasons for the progress or decline during the forecast period. The insightful research report on the Payment Gateways market includes Porters five forces analysis and SWOT analysis to understand the factors impacting consumer and supplier behavior.

Market Segment Analysis

The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth.

Segment by Type Online Mode, Offline Mode

Segment by Application Retail, Catering Industry, Medicine & Cosmetics, Other

Payment Gateways Market: Competitive Landscape

This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019.

Payment Gateways Market: Regional Analysis

The report offers in-depth assessment of the growth and other aspects of the Payment Gateways market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America.

The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2025. These analyses will help the reader to understand the potential worth of investment in a particular region.

Table Of Content

Market Overview: Scope & Product Overview, Classification of Payment Gateways by Product Category (Market Size (Sales), Market Share Comparison by Type (Product Category)), Payment Gateways Market by Application/End Users (Sales (Volume) and Market Share Comparison by Application), Market by Region (Market Size (Value) Comparison by Region, Status and Prospect Payment Gateways Market by Manufacturing Cost Analysis:Key Raw Materials Analysis, Price Trend of Key Raw Materials, Key Suppliers of Raw Materials, Market Concentration Rate of Raw Materials, Proportion of Manufacturing Cost Structure (Raw Materials, Labor Cost), Manufacturing Process Analysis

Key Strategic Developments: The study also includes the key strategic developments of the Payment Gateways market, comprising R&D, new product launch, M&A, agreements, collaborations, partnerships, joint ventures, and regional growth of the leading competitors operating in the market on a global and regional scale.

Key Market Features: The report evaluated key market features, including revenue, price, capacity, capacity utilization rate, gross, production, production rate, consumption, market share, CAGR, and gross margin.

Analytical Tools: The Payment Gateways Market report includes the precisely studied and weighed data of the key industry players and their scope in the Payment Gateways market by means of several analytical tools.

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Anatomic Pathology Market to Surge at a Robust Pace in Terms of Revenue Over 2017 2025 – Bulletin Line

§ August 26th, 2020 § Filed under Nano Medicine Comments Off on Anatomic Pathology Market to Surge at a Robust Pace in Terms of Revenue Over 2017 2025 – Bulletin Line

Global Anatomic Pathology Market: OverviewAnatomic pathology finds application in diagnosis of different types of chronic diseases, namely cancer and infectious diseases. It is also used in pharmaceutical industries to carry out toxicology studies. It is a medical specialty that diagnoses a disease based on microscopic, macroscopic, biochemical, immunologic, and molecular scrutiny of organs and tissues.

Driving growth in the global anatomic pathology market is the rising elderly population, increasing g prevalence of chronic diseases, and a burgeoning world population.

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Global Anatomic Pathology Market: Snapshot

Anatomical Pathology is a specialty in medical science that is related with the diagnosis based on microscopic, macroscopic, immunologic, biochemical, and molecular examination of various tissues and organs. Since many years surgical pathology has advanced incredibly from the primitive method of autopsy into a modernized way. It is also centred on cancer diagnosis and prognosis that helps in taking decisions and act as guide for decision-making in oncology. Rapid increase in cancer such as breast cancer, lung cancer, and colorectal cancer is pushing the global anatomic pathology market.

The need for anatomic pathology market has increased globally as the need for identifying and treating tumor cases have grown at an alarming rate. During last few years the cases related to cancer have risen immensely and the number of deaths related to it has also multiplied many folds. The market has been segmented on the basis of instruments, consumables, and services. Among these segments, service segment is leading the market. The instrument segment is further sub- segmented into slides staining systems, tissue processing system, microtomes, and other instruments. Among these, tissue processing systems is leading the market due to rising automation that have improved the equality for diagnosis processing.

Anatomic pathology includes the diagnosis of various infectious diseases, different types of cancer, and medical conditions by examining tissues and cells samples, which are derived from patients biopsy report. This market is witnessing positive growth due to increasing aging population, growing incidence of chronic diseases, and costly healthcare treatments. Thus the need for anatomic pathology market has increased in recent time. The countries having higher number of aged population are distinct to grow the anatomic pathology market in coming years. Whereas technological advancements in healthcare sector will also act as the driving sector for this market.

Global Anatomic Pathology Market: Key Trends

The global anatomic pathology market has been growing at a good clip powered by the increasing prevalence of chronic diseases such as kidney or liver disease, infectious disease, and autoimmune disease, worldwide. Alarming increase in cancer such as lung cancer, colorectal cancer, and breast cancer is also driving the market as anatomic pathology also aids in diagnosing those.

A massive pool of elderly population has also been driving the market as they are highly susceptible to different types of chronic diseases.

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Global Anatomic Pathology Market: Market Potential

The global market for anatomic pathology holds out a lot of promise. Depending upon the types of products and services, the market can be classified into instruments, consumables, and services. Among the three, the service segment leads.

The instruments segment can be further sub divided into tissue processing systems, microtomes, slides staining systems, and other instruments. Among them, the tissue processing systems segment outshines others because of the rising automation in the instruments that improve the quality of diagnosis process. Likewise, the consumables segment can be further sub-segmented into probes, reagents and antibodies, and kits, among other consumables. The reagents and antibodies segment, of them, hold a sway on account of the rising number of diagnostics tests that require reagents and antibodies.

The services segment in the global market for anatomic pathology can be further classified into cytopathology, histopathology, etc. Histopathology segment is a frontrunner of the two because of their application in the diagnosis of various chronic diseases, ranging from cancer to bacterial and viral diseases.

Application-wise, the market for anatomic pathology can be further subdivided into disease diagnosis, drug discovery and development, etc. Among those, the disease diagnosis segment dominates because of the rising instances of chronic diseases.

Global Anatomic Pathology Market: Regional Outlook

Geographically, the key segments of the market are North America, Asia Pacific, Europe, and the Rest of the World (RoW). North America, of them, dominates the marketbecause of the high prevalence of chronic diseases, increasing aging population, growing uptake of personalized medicine, rising investment by governments in diagnostic research, and concentration of prominent companies in the continent. North America is followed by Europe. Asia pacific and the Rest of the World come in the second and third positions.

Global Antomic Pathology Market: Competitive Analysis

To assess the competition in the global market for anatomic pathology, the report profiles players such as F. Hoffmann-La Roche AG, Thermo Fisher Scientific, Danaher Corporation, Agilent Technologies, Sakura Finetechnical Co., Ltd., Quest Diagnostics Incorporated, Laboratory Corporation of America Holdings, and NeoGenomics Laboratories, Inc.

The report sheds light on their product offerings, prices, key strategies, sales, revenues, and market shares. It leverages market-leading analytical tools to uncover opportunities and threats awaiting them and their trajectory in the near future.

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TMR Research is a premier provider of customized market research and consulting services to business entities keen on succeeding in todays supercharged economic climate. Armed with an experienced, dedicated, and dynamic team of analysts, we are redefining the way our clients conduct business by providing them with authoritative and trusted research studies in tune with the latest methodologies and market trends.

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Rise in Prevalence of Depression that Boosts the Growth of Rosacea Medicine Market In Industry – The Daily Chronicle

§ August 26th, 2020 § Filed under Nano Medicine Comments Off on Rise in Prevalence of Depression that Boosts the Growth of Rosacea Medicine Market In Industry – The Daily Chronicle

Global Rosacea Medicine Market Report 2019 Market Size, Share, Price, Trend and Forecast is a professional and in-depth study on the current state of the global Rosacea Medicine industry.

The report also covers segment data, including: type segment, industry segment, channel segment etc. cover different segment market size, both volume and value. Also cover different industries clients information, which is very important for the manufacturers.

There are 4 key segments covered in this report: competitor segment, product type segment, end use/application segment and geography segment.

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For competitor segment, the report includes global key players of Rosacea Medicine as well as some small players.

Market Segment Analysis The research report includes specific segments by Type and by Application. This study provides information about the sales and revenue during the historic and forecasted period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type, the Rosacea Medicine market is segmented into Prescription Medicine OTC

Segment by Application Oral Administration External Application

Global Rosacea Medicine Market: Regional Analysis The Rosacea Medicine market is analysed and market size information is provided by regions (countries). The report includes country-wise and region-wise market size for the period 2015-2026. It also includes market size and forecast by Type and by Application segment in terms of sales and revenue for the period 2015-2026. The key regions covered in the Rosacea Medicine market report are: North America U.S. Canada Europe Germany France U.K. Italy Russia Asia-Pacific China Japan South Korea India Australia Taiwan Indonesia Thailand Malaysia Philippines Vietnam Latin America Mexico Brazil Argentina Middle East & Africa Turkey Saudi Arabia U.A.E Global Rosacea Medicine Market: Competitive Analysis This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and sales by manufacturers during the forecast period of 2015 to 2019. The major players in global Rosacea Medicine market include: Galderma Laboratories Allergan Inc. Topix Barrier Therapeutics, Inc Bayer AG PharmaDerm Pharmaceuticals, Inc Bristol-Myers Squibb Genentech, Inc. GlaxoSmithKline Plc

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Important Key questions answered in Rosacea Medicine market report:

What will the market growth rate, Overview, and Analysis by Type of Rosacea Medicine in 2024?

What are the key factors affecting market dynamics? What are the drivers, challenges, and business risks in Rosacea Medicine market?

What is Dynamics, This Overview Includes Analysis of Scope and price analysis of top Manufacturers Profiles?

Who Are Opportunities, Risk and Driving Force of Rosacea Medicine market? Knows Upstream Raw Materials Sourcing and Downstream Buyers.

Who are the key manufacturers in space? Business Overview by Type, Applications, Gross Margin, and Market Share

What are the opportunities and threats faced by manufacturers in the global market?

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The content of the study subjects, includes a total of 15 chapters:

Chapter 1, to describe Rosacea Medicine product scope, market overview, market opportunities, market driving force and market risks.

Chapter 2, to profile the top manufacturers of Rosacea Medicine , with price, sales, revenue and global market share of Rosacea Medicine in 2019 and 2015.

Chapter 3, the Rosacea Medicine competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast.

Chapter 4, the Rosacea Medicine breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2019 to 2025.

Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2019 to 2025.

Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2019 to 2025.

Chapter 12, Rosacea Medicine market forecast, by regions, type and application, with sales and revenue, from 2019 to 2025.

Chapter 13, 14 and 15, to describe Rosacea Medicine sales channel, distributors, customers, research findings and conclusion, appendix and data source.

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Rise in Prevalence of Depression that Boosts the Growth of Rosacea Medicine Market In Industry - The Daily Chronicle

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Preparing For the Vaccine Results | In the Pipeline – Science Magazine

§ August 26th, 2020 § Filed under Nano Medicine Comments Off on Preparing For the Vaccine Results | In the Pipeline – Science Magazine

Derek Lowe's commentary on drug discovery and the pharma industry. An editorially independent blog from the publishers of Science Translational Medicine. All content is Dereks own, and he does not in any way speak for his employer.

So lets take a few minutes to think about what happens when the vaccine trials start to read out. Im making the assumption that the data will be freely available in a timely manner (which means before any decisions are made), because the alternative to that is Not Real Good. Another not-real-good alternative would be to declare the first one to read out the instant winner, because (as noted by Anthony Fauci) that would certainly screw up the trials of the others. But if we avoid these mistakes (no guarantees are expressed or implied), there are still a number of fairly likely things that I dont believe the general public is quite ready for.

One of those: what if the first vaccine results arent very impressive? This could happen. Im really hoping it doesnt, but anyone in the business will tell you that you dont know what efficacy is really going to be like until you run an efficacy trial, and that goes for vaccines as much as for anything else. I will say that the available biomarkers (antibodies and T cells) are much stronger in vaccine work than they are in many other areas, but on the other hand, its immunology. Which is full of fun and interesting surprises. So if the first trial to really give a solid efficacy read comes in lower/weaker than wed all like to see, my guess is that the press and the public wont take it too well. There will be a rush to OMG We Cant Make A Vaccine To Corona takes, I think, which will sow some despair and panic. I would expect the stock market not to take the news well, either.

But even if the first results arent great, it doesnt mean that were (necessarily) hosed. Thats the good thing about having several different vaccines going, with different platform technologies. We are really going to have to wait and see what the various approaches are going to produce, even though wait and see is not exactly the zeitgeist right now. We have the different adenoviruses (and other vectors, which will come later), the inactivated-virus vaccines, the mRNA candidates, the recombinant proteins theres no reason to think that these are all going to come out the same, and thats going to be important to keep in mind.

To that point, heres another possibility thats quite possible: the Patchwork Quilt of Efficacy. What if we get a mixture of results, with Vaccine A being pretty good, but not in older patients, while Vaccine B seems better in that cohort but is harder to roll out for distribution, while Vaccine C showed more even results over various patient cohorts but is beaten by some other candidate in any particular one, while Vaccine D was strong but definitely had more adverse events. . .you see what I mean. I can easily imagine something like this happening, and the thing is, its not just going to drop all at once. Were going to get those various results one after the other and will have to fit them into an unavoidably messy picture, adjusting our plans as more data points become available. Overall, I think it could be a serious mistake to declare a winning vaccine too early (unless something comes in just kicking coronavirus ass all over the field, which would frankly be fine), but telling everyone to wait while we see what the next ones bring is probably not going to go over well. There will be tremendous pressure to just start dosing people with anything that looks reasonable, and you cant blame anyone for it.

Regarding those adverse events, Im no immunologist, but the one that Im worried most about is probably Guillain-Barre syndrome. Pronounce that one something like gee-YAH bur-RAY for maximum effect, but Ive heard plenty of other more Anglicized pronunciations in the wild. No matter how you say it, GBS isan autoimmune response that leads to an attack on the myelin sheaths of the nervous system bad news, obviously, but the good part is that most cases resolve. Not all of them do, though, and even many of the resolved ones involve spending time in a hospital in pretty serious condition. GBS happens spontaneously after some respiratory infections, for immunological reasons that are still being worked out, and is most commonly seen in younger women. It can come on after vaccination, in the same way as it can come on after infection, and itswidely recognized as one of the big problems with the 1976 swine flu vaccine rollout, and is certainly something that vaccine developers in general keep an eye out for. We do not want to have to wrestle with this problem, but its a rare enough event that only the large Phase II/Phase III trials will have a chance of giving us a read on it at all. For context, the 1976 vaccine is believed to have caused one extra case of GBS per 100,000 people vaccinated its the sort of thing you might well not pick up on at all until youre going out into the broader population. Teenager Rushed to Hospital After Coronavirus Shot is not a headline that will do anyone any good.

That wider population is always the worry, immunologically. We all have different immune systems thats the point, otherwise one plague or another would have wiped us off the planet by now. The number of rare immune-linked disorders is large and various because of this, and that means that the response to any new vaccine could show some oddities as you start heading out into millions of people Tens or hundreds of millions yeah, you would have to expect some rare and bad events to poke up, and if one of them happens with major media coverage, things could get ugly.

Even if things go well, though and I continue to think that for at least one of the vaccine candidates they will there are some complications. All but one of the vaccines being tested now (J&Js is the exception) will need a booster shot some weeks after the first one. And from the antibody titers weve seen in the Phase I trials, you wouldnt necessarily expect that much protection with just one shot. People are going to have to realize this: the first shot will not mean that youre in the clear, as ready to shed your mask and hit the streets as you might be. For that matter, its still going to take some time after the second shot to reach protective levels, so it seems, so its not like even the booster will mean that you can hit the karaoke bar that evening. We will need to be ready for I Got the Vaccine And I Got Coronavirus Anyway reports that will turn out to be due to one of these situations. The logistics of getting everyone through a two-shot immunization course will be nontrivial, in any event.

OK, I dont want this post to be too depressing we need to keep our eye on the likelihood that were going to see an effective vaccine in the coming months. Thats going to be great, but nothing says that launching it into the world has to happen smoothly. One last point: when we launch that vaccine (or those vaccines), we are not only going to have to be transparent about why the choice was made the way it was: were also going to have to be transparent about who gets it first and why. Frontline medical workers, surely, and others in similar positions. People who do economically vital jobs (supply chains, etc.) whose work unavoidably puts them at higher risk. You can come up with more categories easily, but one category that I hope we avoid is People Who Know Some People. If theres a perception that the well-connected are cutting the line, thats not going to go over well, either, and it shouldnt. I would recommend being completely open about the order of vaccination and trying to stick to it, visibly. Ideally, this should be publicized before we even start getting vaccine readouts, but well see. . .

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‘A culture shift’: How California evacuation centers are dealing with fires and COVID-19 – USA TODAY

§ August 26th, 2020 § Filed under Nano Medicine Comments Off on ‘A culture shift’: How California evacuation centers are dealing with fires and COVID-19 – USA TODAY

A look at the River Fire as it raged Tuesday evening, more than doubling in size. USA TODAY Handout

REDDING, Calif. The thousands of people evacuating from the wildfires burning across California are seeing something new this summer, and as with nearly every other aspect of their lives, the coronavirus drives it.

Pushed by the COVID-19 pandemic and the need for social distancing, shelter managers can no longer rely on large assembly halls at schools, fairgrounds and community centers to house wildfire evacuees.

Rather than eating and sleeping in large, open rooms, many of those displaced are being sent to nearby hotels, said Nicole Maul, a spokeswoman for the American Red Cross, which operatesnumerous shelters up and down California in areas hit by wildfires.

She said the Red Cross has been giving priority to sending people to hotels over having them bunk overnight in large gathering rooms.

"They're noticing it's a little bit different than what they are used to seeing," Maul said."It's been a culture shift for our country and the world."

What we know: 5 dead as over 370 wildfires burn in California right now

California is on fire: What are fire whirls, fire tornadoes, fire clouds and running crown fires?

With the onset of the coronavirus,theRed Cross has been working since January to plan for sheltering people displaced during the summer wildfire season.

There are at least 23 major fires burning in California that have torched hundreds of thousands of acres and forcedthe evacuations of residents all over the state.

Monterey County residents ask for information outside the evacuation center located at the Carmel Middle school on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

Maia Carroll, a spokeswoman for Monterey County, said officials want to get people safely away from fires, but also make sure they stay safe at shelters.

They need to bring face covering with them. They need to plan on social distancing and temperature checks are being done, she said.

The River Fire (61.7 square miles) and the Carmel Fire (7.4 square miles) are both burning in Monterey County.

Its a little complex when we have a life threatening situation right now. The number one priority is life and safety. In terms of COVID we want people to evacuate first and get to a safe location and then at that safe location we can continue with COVID precautions, she said.

Because of COVID, we can't just accept things being dropped off here (donations) so thats something we are concerned about, she said.

Sending fire-displaced residents to motels is not new for the Red Cross. The agency has been working with hotels across the state for many years on a smaller scale, Maul said.

Families burned out of their homes are regularly given vouchers to stay at nearby hotels, Maul said.

The agency continues to use congregate centers for housing wildfire evacuees, but center managers try to keep the number of residents lower at each location to increase social distancing.

That means the Red Cross has had to open more congregate centers with fewer evacuees, Maul said.

In years past, meals were served buffet style, but with the COVID-19 pandemic, evacuees are served packaged meals. And those staying at motels also are delivered packaged meals, she said.

Dr. Jahan Fahimi, associate professor of emergency medicine at the University of California, San Francisco Medical Center said people are less likely to catch COVID if they stay at home or avoid large gatherings.

"Being in public indoors might not be in your best interest," he said.

Gibi Dominguez, a Monterey County employee, puts up a sign outside the evacuation center at WeatherTech Raceway Laguna Seca on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

The risk of exposure to COVID-19 is just one of the concerns for people fleeing wildfires this summer, according toDr. Stephanie Christenson, an assistant professor of medicine at UCSF Medical Center.

She said wildfire smoke, heatand COVID have created a "perfect storm" of risk for certain groups of people with underlying health problems.

The microscopic particles in wildfire smoke can irritate the tissue deep in the lungs and cause inflammation and infections, Christenson said. But this summer, Californians are facing an additional threat from the coronavirus.

"Now we've just given them another insult that can make matters worse," Christenson said.

A young girl plays next to her mother Mini Cho as they both wait to enter the evacuation center in the WeatherTech Raceway Laguna Seca on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

The effects of wildfire smoke may make people more susceptible to COVID-19 and worsen their symptoms, she said.

People with underlying health problems such as heart disease, asthma, diabetes and high blood pressure are especially at risk for symptoms being further exacerbated by smoke and COVID, she said.

"These would be the groups that I would be particularly worried about," she said.

Christenson said that in addition to social distancing, shelter managers should also sanitize congregate areas and make sure residents wear masks andwash their hands regularly.

Maul said before someone is allowed into an evacuation shelter they are given atemperature checks and asked whether they have had any symptoms orhave been exposed to anyone with COVID-19.

Monterey County residents line up at the evacuation center located at the WeatherTech Raceway Laguna Seca on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

Helen Cosentino, a Red Cross Chapters program disaster specialistfor San Benito and Merced counties, said some people, out of concern about the coronavirus,are avoidingevacuation centers.

The fear people have of coming to places like this, we are taking precautions. But I know some people are fearful, some people are choosing to sleep in their cars, said Cosentino.

Follow Damon Arthur on Twitteron Twitter at @damonarthur_RS.

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New Nasal Gel Evaluated for its Protective Action Against Human Rhinovirus 16 (HRV-A16) Infection in – PharmiWeb.com

§ August 25th, 2020 § Filed under Nano Medicine Comments Off on New Nasal Gel Evaluated for its Protective Action Against Human Rhinovirus 16 (HRV-A16) Infection in – PharmiWeb.com

EMMETTEN, Switzerland, August 24, 2020 / B3C newswire / -- MetP Pharma AG today announced that its nasal gel Nascum-VIREX will be evaluated for its protective effect against viral infection. The aim of the study is to test the effect of acute dose apical exposure of Nascum-VIREX upon viral infection with Human Rhinovirus 16 (HRV-A16) using fully differentiated human nasal epithelial cells. Time points from zero to 96 hours are studied for the effect of the nasal gel on virus replication, toxicity markers, cilia and cytokines. The results of the study are expected at the end of October 2020.

Nascum-VIREX is an oil-based nasal gel and a class 1 medical device according to Directive 2007/47/EC which has especially been developed to cover the nasal mucosa for several hours. The nasal gel is highly bio-adhesive and forms a physical barrier in the nasal cavity to significantly trap airborne particles by a mechanical effect. Moreover, through its positive charge, the gel binds negatively charged pathogens and viruses and thus shields the nasal cells from inhaled airborne particles through an electrostatic effect (Coulomb attraction).

The nasal gel might help eliminate pathogens before they enter the body

The nasal cavity is likely the major site of entry of pathogens like SARS-CoV-2 since most of the inhaled air enters the body through the nose. However, the virus must first overcome a 1015 m thick mucus layer in the nose which also contains numerous substances secreted by epithelial cells with inhibitory activity to inhaled pathogens and which is cleared and replenished by the basal epithelium many times per day. Nascum-VIREX supports the mucus in capturing the virus before it infects the epithelium and the microscopic hair-like cilia move the gel-covered mucus in the back of the throat where it is then swallowed and destroyed by the acid in the stomach, or coughed up or sneezed out.

The barrier properties of mucus are often diminished by pre-existing diseases, medications, life style and age. Also, the pathogen itself may cause the disruption of the ciliated epithelium or ciliary dyskinesia thus impairing mucociliary clearance which might facilitate viral infection. To prevent virus entry, it is of primary importance to increase the barrier function of the nose.

Dr. Claudia Mattern, Chief Scientific Officer at MetP Pharma comments: There is no guarantee that there will even be a COVID-19 vaccine and, if so, how long it will protect recipients, quite apart from the fact that it will take several years to develop a safe medication. Nascum-VIREX is immediately available to reduce or even prevent the virus entry at the mucous membrane of the nose thus helping the patients immune system fight the viral infection.

Nascum-VIREX is an antiviral-modified version of Nascum-Plus gel whose robust activity against the transmission noxious particles has already been proved.

Data from a preclinical study with the Nofer Institute of Occupational Medicine has demonstrated that the Nascum gel layer significantly protects against an increase in serum IgE and the BAL inflammation marker TNF after exposure to industrial dust (2). In a clinical study with the Fraunhofer Institute for Toxicology and Experimental Medicine, the nasal gel significantly reduced Total Nasal Symptom Score (TNSS) after pollen challenge in an Allergen Challenge Chamber (3). In both studies the nasal gel was well tolerated.

There are already several approaches to reduce the virus load in the nose to be used in addition to masks. However, conventional methods such as sinus rinsing, nasal powders and nasal sprays are not recommended as they (1) have surfaces that can harbor active virus droplets for hours, potentially increasing the spread of the virus (sinus rinsing), (2) create an acidic environment that may induce changes of the nasal mucosa and reduce ciliary beat frequency (nasal powders) or (3) use negatively charged formulations which cannot bind and inactivate viruses as viruses are also negatively charged (nasal sprays). Most recently, masks made of positively charged fibers have been proposed providing capture efficiency due to Coulomb attraction.

For high resolution please click the image.

About MetP Pharma AG MetP Pharma AG is an independent, specialized pharmaceutical R&D company based in Switzerland. The company has developed an advanced and comprehensively patented nose-to-brain drug delivery system allowing to bypass the blood-brain barrier. The companys internal product development program includes intranasal products for the indications concussion, insomnia, attention deficit hyperactivity disorder (ADHD) and multiple sclerosis (MS). MetP also provides pharmaceutical development and manufacture services based on its proprietary and worldwide patented intranasal delivery technology.

MetPs single-dose nasal applicator Lecticula was among the finalists for the 2016 CPhI Pharma Award in the category "Excellence in Pharma: Drug Delivery Devices".

Contact

MetP Pharma AG Dr. Claudia Mattern CSO +41-41-618 30 30 info@mattern-pharma.com

(1) Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1. The New England Journal of Medicine, April 16, 2020; 382:1564-1567. https://www.nejm.org/doi/10.1056/NEJMc2004973(2) Study at Nofer Institute of Occupational Medicine (NIOM) in Lodz/Poland (scientific Supervision Prof. W. Wqsowicz, head of the Department of Toxicology and Careinogenesis). NIOM is a leading Institute in occupational and environmental health, having the status of a WHO Collaborating Centre. (3) Stru N, Badorrek P, Mattern C, Mattern U, Hohlfeld JM. The Effect of a Thixotropic Nasal Gel on Nasal Symptoms and Inflammatory Biomarkers in Seasonal Allergic Rhinitis. Int Arch Allergy Immunol. 2020;181(5):385-394.

Keywords: Humans; COVID-19 vaccine; COVID-19; Coronavirus; Nasal Cavity; Adhesives; Rhinovirus; Dust; Virus Internalization; severe acute respiratory syndrome coronavirus 2; Coronavirus Infections; Nasal Mucosa

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The 30-Day Gut-Health Reset Will Improve Your Health From the Inside Out – LIVESTRONG.COM

§ August 25th, 2020 § Filed under Nano Medicine Comments Off on The 30-Day Gut-Health Reset Will Improve Your Health From the Inside Out – LIVESTRONG.COM

This 30-day plan focuses on a new aspect of digestive health each week to ensure your gut gets everything it needs (and nothing it doesn't) to function properly.

Image Credit: LIVESTRONG.com Creative

Time for a gut check. No, really: How's your digestive system doing?

If you've been feeling bloated, gassy and/or sluggish, your gut could be trying to tell you something's up. And when your gastrointestinal (GI) tract isn't working like it should be, your overall health struggles, too.

That's why the LIVESTRONG.com team has partnered with Vincent Pedre, MD, author of Happy Gut and creator of the 28-Day Happy Gut Cleanse and the Happy Gut app, for The 30-Day Gut-Health Reset, which starts on September 1, 2020.

The goal of this five-week plan is to get you on the path to optimal gut health even if you don't have any GI distress. It's also an opportunity to reduce or eliminate any uncomfortable symptoms if you are experiencing them.

Keep in mind this challenge is not a replacement for medical care. Always speak with a health care professional about serious symptoms, such as blood when you have a bowel movement, severe abdominal pain, heartburn not relieved by antacids or ongoing vomiting or diarrhea, according to the U.S. National Library of Medicine.

Your digestive system is a complicated operation.

With help from the pancreas, liver and gallbladder, the GI tract a series of linked organs that include the mouth, esophagus, stomach and small and large intestines works to break down the food you eat, extract key nutrients that go to the rest of your body to use as fuel and then eliminate the remaining waste products the body doesn't need, according to the National Institute of Diabetes and Digestive and Kidney Diseases.

But there's more to gut health than digestion. "The gut is a foundation of health," Dr. Pedre says. If you want to optimize your overall health, you have to optimize your gut health, he says. "That foundation is critical to the rest of the body."

For starters, digestive health is essential for your body's immune response, he says. In fact, a large portion of your immune system is in your GI tract, according to Johns Hopkins Medicine. The lining of your gut acts as a physical and chemical barrier, producing antimicrobial substances that neutralize and prevent harmful pathogens from getting to the rest of your body, as noted in a 2017 review in Experimental and Molecular Medicine.

Plus, your gut and brain communicate with each other constantly, thanks to what's called the gut-brain axis or the gut-brain connection. Through chemicals like hormones and neurotransmitters, the brain can modify bacterial behavior in the gut, and vice versa bacteria, viruses and fungi in the gut can affect chemicals in the brain, according to the Cleveland Clinic.

In a February 2019 study in Nature Microbiology, researchers found that people with depression were more likely to have lower "overall bacterial abundance" in their guts, while people who self-reported having a high quality of life were more likely to have two specific types of bacterial species in their guts. That said, more research especially in humans is needed to better understand the gut-brain connection.

Image Credit: LIVESTRONG.com Creative

Read on for more details about and links to each week of the challenge.

Image Credit: LIVESTRONG.com Creative

Your goals for Week 1 are:

You can't fix anything your gut included until you figure out what's going on. That's why the first week of this reset is devoted to getting a clear picture of what's happening with your insides. One of the best ways to do that is with a gut-health tracker.

Starting from Day 1 and continuing throughout the entire month, you'll log what you eat and drink, as well as how you feel after eating. You'll also track your bowel movements because (no major surprise here) they can be very telling of your gut health.

This week, you'll also check your fiber and water intake. Both play important roles in healthy gut function. Most people should aim for 21 to 38 grams of fiber daily, per the U.S. National Library of Medicine. And, in general, aim for 2.7 liters (about 11 cups) to 3.7 liters (about 15 cups) of water each day, according to the National Academies of Sciences.

Get the full Week 1 plan here.

Your goals for Week 2 are:

Once you know a bit more about your diet and how it's making you feel, you can start to eliminate foods and activities that are potentially causing GI distress. That means saying buh-bye to added sugars, artificial sweeteners, highly processed foods, alcohol and high-intensity workouts (sorry, HIIT lovers).

"During this time, we want to take away all the things that are going to promote inflammation while we're re-working the internal environment in your body to become more anti-inflammatory," Dr. Pedre says.

Be aware that this is likely the toughest week of the challenge. During this phase, you might feel worse before you start to feel better, as your body adjusts to a healthier diet, Dr. Pedre says.

But stay strong: "After you come out the other side, you're going to feel the best you've felt in a long time," he says.

Get the full Week 2 plan here.

Your goals for Week 3 are:

Removing or reducing potential causes of inflammation in your digestive system is a great start, but now it's time to introduce some new things that will help your gut stay healthy and balanced.

That starts with probiotics and prebiotics. Probiotics are good-for-your-gut microscopic organisms that live in your GI tract; in healthy amounts, they help keep symptoms like diarrhea and constipation at bay, Dr. Pedre says. Prebiotics, on the other hand, are non-digestible food ingredients that fuel probiotic growth. "With the prebiotics, you're promoting the good bacteria," he says.

This week, you'll discover which foods contain probiotics and prebiotics and how to combine them to keep your gut balanced, as well as a variety of fiber-rich, digestion-supporting foods to include in your diet and the best workouts to keep things moving.

Get the full Week 3 plan here.

Your goals for Week 4 are:

In a world that makes multitasking feel mandatory, it's important to slow things down now and then, especially when it comes to eating and exercise. Constantly snacking on the move or making all your sweat sessions super high-intensity can leave you stressed out and lethargic.

"When you eat at your desk in five minutes, you're in a stressed-out state. You can't digest well in that state," Dr. Pedre says. That's where mindful eating practices think: chewing your food thoroughly and pausing between bites can help.

"You need to rest to digest," he says. "In other words, you need to give your gut space by slowing down in order to digest better."

And because you likely already want to limit stress, you'll want to make sure your gut health is in order, as there's a strong connection between the two.

"We're wired to shut down the gut in a stressed state," Dr. Pedre says. If you're under constant pressure, it's quite likely your gut won't function properly, he explains, potentially leading to an upset stomach or intestinal discomfort.

This week, try doing yoga, meditating, connecting with friends or keeping a gratitude journal to help circumvent that stress and its negative effects on digestion.

Get the full Week 4 plan here.

Your goals for Week 5 are:

The first four weeks of this plan focus on the changes that will have the biggest effect on your gut health. But Week 5 is about making a few minor adjustments to your daily routine that, when combined, add up to better GI function.

"Water is really important for the movement of substances through the body [especially in your gut], which is why it's critical to get the right amount," Dr. Pedre says.

The quality and quantity of your sleep can affect your gut health, too. Sleeping longer and sleeping well was correlated with a more diverse gut microbiome, per a small October 2017 PLOS One study in men, and getting too little sleep can send you searching for high-carb, high-fat pick-me-ups that won't do your gut any favors, Dr. Pedre says. Aim for seven to nine hours a night, going to bed and waking up at relatively the same times.

Lastly, this is the week to check back in with your tracker and see if you notice any particular foods or drinks that have been causing a pattern of GI symptoms. Then, chat with your doctor about any trends to see if you'd benefit from tests or treatment.

Get the full Week 5 plan here.

To reduce the risk of spreading COVID-19 infections, it is best to call your doctor before leaving the house if you are experiencing a high fever, shortness of breath or another, more serious symptom.

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Congenital Heart Disease Occluder Market COVID 19 Growth Rate, Increasing Demands, Status and Application Forecast to 2026- AGA medicine, Pioneer…

§ August 25th, 2020 § Filed under Nano Medicine Comments Off on Congenital Heart Disease Occluder Market COVID 19 Growth Rate, Increasing Demands, Status and Application Forecast to 2026- AGA medicine, Pioneer…

Los Angles United States, August 2020: The Congenital Heart Disease Occluder Market steadily escalating demand due to improving purchasing power is projected to bode well for the global market. WMRlatest publication, Titled Congenital Heart Disease Occluder Market Research Report 2020, offers an insightful take on the drivers and restraints present in the market. It assesses the historical data pertaining to the Congenital Heart Disease Occluder market and compares it to the current market trends to give the readers a detailed analysis of the trajectory of the market. A team subject-matter experts have provided the readers a qualitative and quantitative data about the market and the various elements associated with it.

The new report offers a powerful combination of latest, in-depth research studies on the Congenital Heart Disease Occluder market. The authors of the report are highly experienced analysts and possess deep market knowledge. Some of the key players operating in this Report are:AGA medicine, Pioneer Technology Co, Beijing Huayi Shengjie, PFM Medical, Universal Health Care

Get Free Sample of the Report to understand the structure of the complete report (Including Full TOC, Table & Figures):https://www.worldwidemarketreports.com/sample/362247

Congenital Heart Disease Occluder Players/Suppliers Profiles and Sales Data:Company, Company Basic Information, Manufacturing Base and Competitors, Product Category, Application and Specification with Sales, Revenue, Price and Gross Margin, Main Business/Business Overview.

The Best part of this report is, this analyses the current state where all are fighting with the covid-19, The report also provides the market impact and new opportunities created due to the Covid19 catastrophe.

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Key Benefits for Stakeholders

The study provides an in-depth analysis of the Congenital Heart Disease Occluder market size along with the current trends and future estimations to elucidate the imminent investment pockets. Information about key drivers, restraints, and opportunities and their impact analysis on the market size is provided. Porters five forces analysis illustrates the potency of buyers and suppliers operating in the portable gaming industry. The quantitative analysis of the Congenital Heart Disease Occluder industry from 2020 to 2026 is provided to determine the Congenital Heart Disease Occluder market potential.

The research report is broken down into chapters, which are introduced by the executive summary. Its the introductory part of the chapter, which includes details about global market figures, both historical and estimates. The executive summary also provides a brief about the segments and the reasons for the progress or decline during the forecast period. The insightful research report on the Congenital Heart Disease Occluder market includes Porters five forces analysis and SWOT analysis to understand the factors impacting consumer and supplier behavior.

Market Segment Analysis

The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth.

Segment by Type Patent Ductus Arteriosis (PDA), Atrial Septal Defects (ASD), Ventricular Septal Defects (VSD)

Segment by Application Hospital, Clinic, Others

Congenital Heart Disease Occluder Market: Competitive Landscape

This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019.

Congenital Heart Disease Occluder Market: Regional Analysis

The report offers in-depth assessment of the growth and other aspects of the Congenital Heart Disease Occluder market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America.

The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2025. These analyses will help the reader to understand the potential worth of investment in a particular region.

Table Of Content

Market Overview: Scope & Product Overview, Classification of Congenital Heart Disease Occluder by Product Category (Market Size (Sales), Market Share Comparison by Type (Product Category)), Congenital Heart Disease Occluder Market by Application/End Users (Sales (Volume) and Market Share Comparison by Application), Market by Region (Market Size (Value) Comparison by Region, Status and Prospect Congenital Heart Disease Occluder Market by Manufacturing Cost Analysis:Key Raw Materials Analysis, Price Trend of Key Raw Materials, Key Suppliers of Raw Materials, Market Concentration Rate of Raw Materials, Proportion of Manufacturing Cost Structure (Raw Materials, Labor Cost), Manufacturing Process Analysis

Key Strategic Developments: The study also includes the key strategic developments of the Congenital Heart Disease Occluder market, comprising R&D, new product launch, M&A, agreements, collaborations, partnerships, joint ventures, and regional growth of the leading competitors operating in the market on a global and regional scale.

Key Market Features: The report evaluated key market features, including revenue, price, capacity, capacity utilization rate, gross, production, production rate, consumption, market share, CAGR, and gross margin.

Analytical Tools: The Congenital Heart Disease Occluder Market report includes the precisely studied and weighed data of the key industry players and their scope in the Congenital Heart Disease Occluder market by means of several analytical tools.

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Healthcare Nanotechnology (Nanomedicine) Market Analysis, Key Players, Industry Segments And Forecast To 2026 – The News Brok

§ August 20th, 2020 § Filed under Nano Medicine Comments Off on Healthcare Nanotechnology (Nanomedicine) Market Analysis, Key Players, Industry Segments And Forecast To 2026 – The News Brok

The Healthcare Nanotechnology (Nanomedicine) market report 2020-2026 provides in-depth study of market competitive situation, product scope, market overview, opportunities, driving force and market risks. Profile the Top Key Players of Healthcare Nanotechnology (Nanomedicine), with sales, revenue and global market share of Healthcare Nanotechnology (Nanomedicine) are analyzed emphatically by landscape contrast and speak to info. Upstream raw materials and instrumentation and downstream demand analysis is additionally administrated. The Healthcare Nanotechnology (Nanomedicine) market business development trends and selling channels square measure analyzed. From a global perspective, It also represents overall industry size by analyzing qualitative insights and historical data.

Key players operating in the global Healthcare Nanotechnology (Nanomedicine) market includes : Amgen, Teva Pharmaceuticals, Abbott, UCB, Roche, Celgene, Sanofi, Merck & Co, Biogen, Stryker, Gilead Sciences, Pfizer, 3M Company, Johnson & Johnson, Smith&Nephew, Leadiant Biosciences, Kyowa Hakko Kirin, Shire, Ipsen, Endo International, and among others.

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Key Target Audience of the Healthcare Nanotechnology (Nanomedicine) market:

Scope of Healthcare Nanotechnology (Nanomedicine) Market:

The global Healthcare Nanotechnology (Nanomedicine) market is valued at million US$ in 2019 and will reach million US$ by the end of 2026, growing at a CAGR of during 2020-2026. The objectives of this study are to define, segment, and project the size of the Healthcare Nanotechnology (Nanomedicine) market based on company, product type, application and key regions.

On the whole, the report proves to be an effective tool that players can use to gain a competitive edge over their competitors and ensure lasting success in the global Healthcare Nanotechnology (Nanomedicine) market. All of the findings, data, and information provided in the report are validated and revalidated with the help of trustworthy sources. The analysts who have authored the report took a unique and industry-best research and analysis approach for an in-depth study of the global Healthcare Nanotechnology (Nanomedicine) market.

The report offers an exhaustive geographical analysis of the global Healthcare Nanotechnology (Nanomedicine) market, covering important regions, viz, North America, Europe, China, Japan, Southeast Asia, India and Central & South America. It also covers key countries (regions), viz, U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, India, Australia, Taiwan, Indonesia, Thailand, Malaysia, Philippines, Vietnam, Mexico, Brazil, Turkey, Saudi Arabia, U.A.E, etc.

The end users/applications and product categories analysis:

On the basis on the end users/applications,this report focuses on the status and outlook for major applications/end users, sales volume, market share and growth rate foreach application.

On the basis of product,this report displays the sales volume, revenue (Million USD), product price, market share and growth rate ofeach type.

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Healthcare Nanotechnology (Nanomedicine) Market The Regional analysis covers:

Key Findings & Data Available in Healthcare Nanotechnology (Nanomedicine) Market Report:

And Many More.

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Nanotechnology in Medical Market 2020 Explain What is the current size of the market? And key players analysis: Roche, Mitsui Chemicals, Camurus,…

§ August 20th, 2020 § Filed under Nano Medicine Comments Off on Nanotechnology in Medical Market 2020 Explain What is the current size of the market? And key players analysis: Roche, Mitsui Chemicals, Camurus,…

A complete research offering of comprehensive analysis of the market share, size, recent developments, and trends can be availed in this latest report by Big Market Research.

As per the report, theGlobal Nanotechnology in Medical Marketis anticipated to witness significant growth during the forecast period from 2020to 2025.

The report provides brief summary and detailed insights of the market by collecting data from the industry experts and several prevalent in the market. Besides this, the report offers a detailed analysis of geographical areas and describes the competitive scenario to assist investor, prominent players, and new entrants to obtain a major share of the global Nanotechnology in Medical market.

Our analysis involves the study of the market taking into consideration the impact of the COVID-19 pandemic. Please get in touch with us to get your hands on an exhaustive coverage of the impact of the current situation on the market. Our expert team of analysts will provide as per report customized to your requirement. For more connect with us at [emailprotected] or call toll free: +1-800-910-6452

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The report presents a summary of each market segment such as type, end-user, applications, and region. With the help of pie charts, graphs, comparison tables, and progress charts a complete overview of the market share, size, and revenue, and growth patterns areaccessible in the report.

Additionally, an outline of each market segments such as end user, product type, application, and region are offered in the report.The market across various regions is analyzed in the report which includes North America, Europe, Asia-Pacific, and LAMEA.The report explains future trends and growth opportunities in every region. These insights help in understanding the global trends in the market and form strategies to be implemented in the future. Moreover, the research report profiles some of the leading companies in the global Nanotechnology in Medical industry. It mentions their strategic initiatives and offers a brief about their business. Some of the players profiled in the global Nanotechnology in Medical market include:

Key players in the Nanotechnology in Medical covers : Roche Mitsui Chemicals Camurus Merck Celgene Cytimmune Amgen Access Pfizer Smith and Nephew Novartis Dentsply International 3M

Analysts have also stated the research and development activities of these companies and provided complete information about their existing products and services. Additionally, the report offers a superior view over different factors driving or constraining the development of the market.

The Nanotechnology in Medical can be split based on product types, major applications, and important countries as follows:

The basis of applications, the Nanotechnology in Medical from 2015 to 2025 covers: Hospitals Clinics Others

The basis of types, the Nanotechnology in Medical from 2015 to 2025 is primarily split into: Nano Medicine Nano Diagnosis Other

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The report clearly shows that the Nanotechnology in Medical industry has achieved remarkable progress since 2025 with numerous significant developments boosting the growth of the market. This report is prepared based on a detailed assessment of the industry by experts. To conclude, stakeholders, investors, product managers, marketing executives, and other experts in search of factual data on supply, demand, and future predictions would find the report valuable.

The report constitutes: Chapter 1 provides an overview of Nanotechnology in Medical market, containing global revenue, global production, sales, and CAGR. The forecast and analysis of Nanotechnology in Medical market by type, application, and region are also presented in this chapter. Chapter 2 is about the market landscape and major players. It provides competitive situation and market concentration status along with the basic information of these players. Chapter 3 provides a full-scale analysis of major players in Nanotechnology in Medical industry. The basic information, as well as the profiles, applications and specifications of products market performance along with Business Overview are offered. Chapter 4 gives a worldwide view of Nanotechnology in Medical market. It includes production, market share revenue, price, and the growth rate by type. Chapter 5 focuses on the application of Nanotechnology in Medical, by analyzing the consumption and its growth rate of each application. Chapter 6 is about production, consumption, export, and import of Nanotechnology in Medical in each region. Chapter 7 pays attention to the production, revenue, price and gross margin of Nanotechnology in Medical in markets of different regions. The analysis on production, revenue, price and gross margin of the global market is covered in this part. Chapter 8 concentrates on manufacturing analysis, including key raw material analysis, cost structure analysis and process analysis, making up a comprehensive analysis of manufacturing cost. Chapter 9 introduces the industrial chain of Nanotechnology in Medical. Industrial chain analysis, raw material sources and downstream buyers are analyzed in this chapter. Chapter 10 provides clear insights into market dynamics. Chapter 11 prospects the whole Nanotechnology in Medical market, including the global production and revenue forecast, regional forecast. It also foresees the Nanotechnology in Medical market by type and application. Chapter 12 concludes the research findings and refines all the highlights of the study. Chapter 13 introduces the research methodology and sources of research data for your understanding.

Years considered for this report: Historical Years: 2015-2019 Base Year: 2019 Estimated Year: 2020 Forecast Period: 2020-2025

About Us: Big Market Research has a range of research reports from various publishers across the world. Our database of reports of various market categories and sub-categories would help to find the exact report you may be looking for. We are instrumental in providing quantitative and qualitative insights on your area of interest by bringing reports from various publishers at one place to save your time and money. A lot of organizations across the world are gaining profits and great benefits from information gained through reports sourced by us.

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Fighting cancer with rejection-resistant, ‘off-the-shelf’ therapeutic T cells – Baylor College of Medicine News

§ August 20th, 2020 § Filed under Nano Medicine Comments Off on Fighting cancer with rejection-resistant, ‘off-the-shelf’ therapeutic T cells – Baylor College of Medicine News

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in teaching the bodys immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors.

Cancer patients today can be a part of the following clinical scenario: a patient comes to the hospital where physicians and scientists analyze his or her tumor to identify cancer-specific markers that would serve as targets for the novel therapy. Blood is drawn from the patient and sent to Baylor College of Medicines Center for Cell and Gene Therapy where the immune T cells are transformed into cells with a mission to identify and kill cells with the tumor-specific tags. The final cells are infused back into the patient to complete their job.

At the Center, we genetically engineer the patients T cells to arm them with the tools they need to identify the patients tumor-specific markers and eliminate the cancer, said Dr. Maksim Mamonkin, assistant professor of pathology & immunology and member of the Center for Cell and Gene Therapy at Baylor.

Although this treatment can effectively eliminate tumors, the training of the T cells is complex and expensive. Sometimes, the trained T cells are not highly potent because the patient already received a number of treatments that weakened the immune cells we work with, Mamonkin said.

In addition, the process to manufacture the therapeutic T cells is time consuming. Sometimes it takes weeks to get the T cells ready, and in this time the patient may take a turn for the worse, Mamonkin said.

Now that we know that this type of cell immunotherapy has a lot of promise, the next step is to streamline it, make it more accessible and make sure that the resulting T cells have the highest potency, said Mamonkin, who also is a member of the Dan L Duncan Comprehensive Cancer Center.

Researchers are developing ready-to-use, off-the-shelf therapeutic T cells. These are genetically engineered T cells that are manufactured from normal, healthy donors. The cells are expanded and well characterized, and have shown to be effective at killing cancer cells. The cells are cryo-preserved stored frozen in liquid nitrogen until its time to use them.

In this scenario, a cancer patient comes to the hospital and the tumor markers are identified. Then, with the identity of the tumor-specific tags in hand, the physician goes to a room filled with large below-zero freezers searching for the one that holds little containers with healthy immune T cells that have been genetically engineered to recognize and destroy cells with the patients cancer-specific markers. These off-the-shelf, ready-made cells are thawed, prepared and infused into the patient several days later.

This approach solves two limitations of the original approach: it avoids the time-consuming, elaborate steps of training and expanding the patients cells and results in therapeutic T cells of higher potency, Mamonkin said. However, the novel approach presents a new set of limitations.

One of the limitations of the off-the-shelf approach emerges when the therapeutic T cells enter the patients body. The patients own immune system recognizes the cells as foreign, such as it happens with organ transplants, and may reject the therapeutic cells.

This is a major problem because rejection not only would reduce the duration of the T cells activity against the tumor, but also would preclude giving subsequent doses of cells. The immune system would reject subsequent doses of the cells right way, said first author, Feiyan Mo, graduate student in Mamonkins lab. To solve this problem we thought that the best defense was a good offense.

The researchers gave the therapeutic T cells a tool that would enable them to fight back the attack of the patients immune cells against them. They genetically engineered the therapeutic T cells to express a receptor called alloimmune defense receptor, or ADR. ADR recognizes a specific molecule, called 4-1BB, that is only expressed on the patients activated T cells and natural killer (NK) cells that would attack them. 4-1BB is not expressed on resting T and NK cells that do not turn against the therapeutic T cells.

Both experiments in the lab and animal models with blood cancers or solid tumors showed that ADR protected off-the-shelf therapeutic T cells from being rejected, Mo said. Not only did they resist rejection, but they also expanded more and persisted longer than therapeutic T cells without ADR.

The researchers are optimistic that this approach may also work in patients. They plan to conduct clinical trials on 2021.

If successful, this approach can be extended to targeting other disease-causing T-cells, such as those rejecting transplanted organs, mediating graft-versus-host disease or perpetuating autoimmunity, said Mamonkin. We are very excited to develop this concept for several applications beyond cancer therapy.

The ADR technology has been licensed to Fate Therapeutics, a clinical-stage biopharmaceutical company that plans on integrating it into their clinical products.

The BCM Ventures team is very pleased to partner with Fate Therapeutics in a licensing relationship to support their implementation of the ADR technology developed in the Mamonkin laboratory here at Baylor. This approach promises to enhance the effectiveness of off-the-shelf cell therapies, and it will now be used more extensively in the clinical setting which stands to benefit patients, said Michael Dilling, director of Baylor Licensing Group. BCM has been an innovator in the development of cell therapies and the commercial sector increasingly looks to BCM as a source for new innovations.

Feiyan Mo, who took the lead on this work, has received an NIH NCI F99/F00 Predoctoral-to-postdoctoral Fellowship Award to help facilitate the translation of ADR to the clinic and continue postdoctoral studies in cancer biology. She is a Baylor graduate student and is co-mentored by Drs. Mamonkin, Malcolm Brenner and Helen Heslop.

Are you interested in learning all the details of this work? Find them in the journal Nature Biotechnology.

Other contributors of this study include Norihiro Watanabe, Mary K. McKenna, M. John Hicks, Madhuwanti Srinivasan, Diogo Gomes-Silva, Erden Atilla, Tyler Smith, Pinar Ataca Atilla, Royce Ma, David Quach, Helen E. Heslop and Malcolm K. Brenner. The authors are affiliated with one of more of the following institutions Baylor College of Medicine, Texas Childrens Hospital and Houston Methodist Hospital.

This project was supported by the Leukemia and Lymphoma Society Translational Research Award no. 6566, NIH NCI SPORE in Lymphoma 5P50CA126752, SU2C/AACR 604817 MegVosburg T cell Lymphoma Dream Team, Gloria Levin Fund and CPRIT Award nos. RP180810 and RP150611. Stand Up To Cancer is a program of the Entertainment Industry Foundation administered by the American Association for Cancer Research. The Dan L Duncan Comprehensive Cancer Center also provided support through its shared resources (P30 CA125123).

By Ana Mara Rodrguez, Ph.D.

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‘It’s been a culture shift’: Evacuation centers deal with wildfires and COVID-19 – Record Searchlight

§ August 20th, 2020 § Filed under Nano Medicine Comments Off on ‘It’s been a culture shift’: Evacuation centers deal with wildfires and COVID-19 – Record Searchlight

A look at the River Fire as it raged Tuesday evening, more than doubling in size. USA TODAY Handout

The thousands of people evacuating from the wildfires burning across California are seeing something new this summer, and as with nearly every other aspect of their lives, the coronavirus drives it.

Pushed by the COVID-19 pandemic and the need for social distancing, shelter managers can no longer rely on large assembly halls at schools, fairgrounds and community centers to house wildfire evacuees.

What we know about the fires: 3-4 Fire now 15,250 acres; now called Elkhorn Fire

Rather than eating and sleeping in large, open rooms, many of those displaced are being sent to nearby hotels, said Nicole Maul, a spokeswoman for the American Red Cross, which operatesnumerous shelters up and down California in areas hit by wildfires.

She said the Red Cross has been giving priority to sending people to hotels over having them bunk overnight in large gathering rooms.

"They're noticing it's a little bit different than what they are used to seeing," Maul said."It's been a culture shift for our country and the world."

With the onset of the coronavirus,theRed Cross has been working since January to plan for sheltering people displaced during the summer wildfire season.

There are at least 23 major fires burning in California that have torched hundreds of thousands of acres and forcedthe evacuations of residents from Tehama County in the north to Riverside in the south.

Monterey County residents ask for information outside the evacuation center located at the Carmel Middle school on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

Maia Carroll, a spokeswoman for Monterey County, said officials want to get people safely away from fires, but also make sure they stay safe at shelters.

They need to bring face covering with them. They need to plan on social distancing and temperature checks are being done, she said.

(Story continues below)

The River Fire (33,653 acres) and the Carmel Fire (4,285 acres) are both burning in Monterey County.

Its a little complex when we have a life threatening situation right now. The number one priority is life and safety. In terms of COVID we want people to evacuate first and get to a safe location and then at that safe location we can continue with COVID precautions, she said.

In terms of COVID we want people to evacuate first and get to a safe location and then at that safe location we can continue with COVID precautions.

Because of COVID, we can't just accept things being dropped off here (donations) so thats something we are concerned about, she said.

Sending fire-displaced residents to motels is not new for the Red Cross. The agency has been working with hotels across the state for many years on a smaller scale, Maul said.

Families burned out of their homes are regularly given vouchers to stay at nearby hotels, Maul said.

The agency continues to use congregate centers for housing wildfire evacuees, but center managers try to keep the number of residents lower at each location to increase social distancing.

That means the Red Cross has had to open more congregate centers with fewer evacuees, Maul said.

In years past, meals were served buffet style, but with the COVID-19 pandemic, evacuees are served packaged meals. And those staying at motels also are delivered packaged meals, she said.

Gibi Dominguez, a Monterey County employee, puts up a sign outside the evacuation center at WeatherTech Raceway Laguna Seca on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

Dr. Jahan Fahimi, associate professor of emergency medicine at the University of California, San Francisco Medical Center said people are less likely to catch COVID if they stay at home or avoid large gatherings.

"Being in public indoors might not be in your best interest," he said.

The risk of exposure to COVID-19 is just one of the concerns for people fleeing wildfires this summer, according toDr. Stephanie Christenson, an assistant professor of medicine at UCSF Medical Center.

She said wildfire smoke, heatand COVID have created a "perfect storm" of risk for certain groups of people with underlying health problems.

The microscopic particles in wildfire smoke can irritate the tissue deep in the lungs and cause inflammation and infections, Christenson said. But this summer, Californians are facing an additional threat from the coronavirus.

A young girl plays next to her mother Mini Cho as they both wait to enter the evacuation center in the WeatherTech Raceway Laguna Seca on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

"Now we've just given them another insult that can make matters worse," Christenson said.

The effects of wildfire smoke may make people more susceptible to COVID-19 and worsen their symptoms, she said.

People with underlying health problems such as heart disease, asthma, diabetes and high blood pressure are especially at risk for symptoms being further exacerbated by smoke and COVID, she said.

"These would be the groups that I would be particularly worried about," she said.

Christenson said that in addition to social distancing, shelter managers should also sanitize congregate areas and make sure residents wear masks andwash their hands regularly.

Maul said before someone is allowed into an evacuation shelter they are given atemperature checks and asked whether they have had any symptoms orhave been exposed to anyone with COVID-19.

Monterey County residents line up at the evacuation center located at the WeatherTech Raceway Laguna Seca on Aug. 20, 2020.(Photo: David Rodriguez/The Salinas Californian)

Helen Cosentino, a Red Cross Chapters program disaster specialistfor San Benito and Merced counties, said some people, out of concern about the coronavirus,are avoidingevacuation centers.

The fear people have of coming to places like this, we are taking precautions. But I know some people are fearful, some people are choosing to sleep in their cars, said Cosentino, who was working at a shelter at Carmel Middle School.

Damon Arthur is the Record Searchlights resources and environmentreporter. He is among the first on the scene at breaking news incidents, reporting real time on Twitter at@damonarthur_RS. Damon is part of a dedicated team of journalists who investigate wrongdoing and find the unheard voices to tell the stories of the North State. He welcomes story tips at 530-338-8834 and damon.arthur@redding.com. Help local journalism thrive bysubscribing today!

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Microplastics Found In Human Organs And Tissues For The First Time – IFLScience

§ August 20th, 2020 § Filed under Nano Medicine Comments Off on Microplastics Found In Human Organs And Tissues For The First Time – IFLScience

Microscopic specks of plastic can be found in practically every nook and cranny of Earths environment. For the first time, scientists have now shown that microplastics and nanoplastics can be found in the organs and tissues of humans.

Scientists at Arizona State University discovered the presence of at least one form of plastic in all 47 samples taken from the lungs, liver, spleen, and kidneys of deceased people who had donated their body to science.

Bisphenol A (BPA), a precursor to important plastics used for food containers and packaging, was found in 100 percent of the samples studied. The team also found types of plastic commonly used in consumer products, such as polycarbonate (PC), polyethylene terephthalate (PET), and polyethylene (PE) in many of the samples.

The researchers presented their findings on Monday, August 17, at the American Chemical Society (ACS) Fall 2020 Virtual Meeting & Expo, in which they explained that-Raman spectrometry imaging techniques wereused to reach these conclusions.

You can find plastics contaminating the environment at virtually every location on the globe, and in a few short decades, weve gone from seeing plastic as a wonderful benefit to considering it a threat, Charles Rolsky, a researcher of aquatic microplastics at Arizona State who is presenting the work at the meeting, said in a statement.Theres evidence that plastic is making its way into our bodies, but very few studies have looked for it there. And at this point, we dont know whether this plastic is just a nuisance or whether it represents a human health hazard."

Microplastics are defined as plastic fragments less than 5 millimeters in diameter, while nanoplastics are even smaller with diameters of less than 0.001 millimeters.

Back in 2018, scientists revealed that human poop is riddled with microplastics, indicating the materials arepervasive in the human gut.The researchers also suggested it was fairly inevitable that the smallest microplastic particles were capable of entering the bloodstream, lymphatic system, and perhaps liver. However, this new research is the first time scientists have directly examined microplastics and nanoplastics in human organs and tissues.

All of the donors had provided the researchers with a detailed history of their lifestyle, diets, and jobs, so the team says they managed to gainsome insight into how these human-made materials became deeply integrated into their bodies.

The idea of non-biodegradable industrial materials lurking in your liver might sound pretty grim, but the researchers were quick to point out that the health implications of this are not yet clear.

We never want to be alarmist, but it is concerning that these non-biodegradable materials that are present everywhere can enter and accumulate in human tissues, and we dont know the possible health effects, Kelkar says. Once we get a better idea of whats in the tissues, we can conduct epidemiological studies to assess human health outcomes. That way, we can start to understand the potential health risks, if any.

Broadly speaking, the effects of microplastic on animal health are not widely agreed upon. The World Health Organization (WHO) has said theres no evidence to indicate human health concern of microplastics in drinking water, although they added this is based on the limited amount of information currently available.

On the other hand, some research has suggested otherwise. Many of these concernsfocus on Bisphenol A (BPA). TheUS Food and Drug Administration (FDA) says that BPA is considered safe at the current levels occurring in foods, although they note there is some concern about the potential effects of BPA on the brain, behavior, and prostate gland in fetuses, infants, and young children.

Regardless of its effect on health, the discovery of microplastics and nanoplastics in human organs certainly goes to show how pervasive these human-made materials have become in under a century.

Edited 19/08/2020: This article previously suggested thatBisphenol A (BPA) was a type of plastic when it is actually acompoundused in the manufacturing of certain plastics. The article has since been corrected.

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Global Nanotechnology in Medical Market 2020: Remarking Enormous Growth with Recent Trends ,Leading Vendors,By Types and Application, By End Users and…

§ August 19th, 2020 § Filed under Nano Medicine Comments Off on Global Nanotechnology in Medical Market 2020: Remarking Enormous Growth with Recent Trends ,Leading Vendors,By Types and Application, By End Users and…

A comprehensive research report namelyGlobal Nanotechnology in Medical Market which discloses an all-encompassing breakdown of the global industry by delivering detailed information about Forthcoming Trends. The Nanotechnology in Medical Market report delivers an exhaustive analysis of global market size, segmentation market growth, market share, competitive Landscape also an in-depth study of the market enlightening key forecast to 2027, recent developments, opportunities analysis, strategic market growth analysis, and technological innovations.

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Major Companies Profiled in This Nanotechnology in Medical Market Report:

3M Cytimmune Novartis Camurus Merck Amgen Access Roche Celgene Mitsui Chemicals Smith and Nephew Pfizer Dentsply International

Nanotechnology in Medical Market report Segmentation: North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa. This report similarly reduces the current, past, and upcoming market business strategies, estimation analysis having a place with the forecast conditions.

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This all-inclusive study covers an overview of various aspects of the industry including outlook, current Nanotechnology in Medical Market trends, and advance during the forecast period. Along with this, an in-depth analysis of each section of the report is also provided in the report that consists of the strategies adopted by the key players, challenges, and threats as well as advancements in the industry.

Nanotechnology in Medical Market Segmentation by Type:

Nano Medicine Nano Diagnosis Other

Based on End Users/Application, the Nanotechnology in Medical Market has been segmented into:

Hospitals Clinics Others

Years Considered to Estimate the Nanotechnology in Medical Market Size:

History Year: 2015-2019

Base Year: 2019

Estimated Year: 2020

Forecast Year: 2020-2027

Do Make an inquiry of Nanotechnology in Medical Market Research [emailprotected] https://www.reportspedia.com/report/others/2015-2027-global-nanotechnology-in-medical-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/64313#inquiry_before_buying

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Global Nanotechnology in Medical Market 2020: Remarking Enormous Growth with Recent Trends ,Leading Vendors,By Types and Application, By End Users and...

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Can Secondhand Smoke Transmit the Novel Coronavirus? – Healthline

§ August 18th, 2020 § Filed under Nano Medicine Comments Off on Can Secondhand Smoke Transmit the Novel Coronavirus? – Healthline

Secondhand smoke has always been a killer, but COVID-19 has made exposure to tobacco smoke potentially deadlier.

And exhaled e-cigarette vapor may be even more dangerous.

Experts say both cigarette and e-cigarette smoke can transport the novel coronavirus, which travels from person to person on microscopic droplets of water vapor exhaled from the lungs.

When a vaping cloud is exhaled, it contains an enormous amount of particles, Loren Wold, PhD, an expert in airborne particulate matter, director of Biomedical Research in the College of Nursing, and an associate professor in the Colleges of Nursing and Medicine at The Ohio State University, told Healthline.

What we dont know is how far the particles can go. We know that the virus can attach to particles and can travel three, four, or five times farther than they would by simply being in the air.

Even just normal breathing can spread the disease, which is why face masks are recommended to keep virus particles from spreading freely through the air.

In addition, smokers arent wearing masks when theyre dragging on a cigarette or vaping. Wold says smokers often exhale more forcefully, meaning that the particles they push out of their lungs can travel even farther.

In some competitions called cloud chasing, vapers push clouds of visible vapor from their lungs up to 6 feet.

A 2017 study also found that e-cigarette users saw the ability to generate a large cloud of exhaled vapor as one of the most attractive aspects of vaping.

The cloud gives you a very good idea of how far you need to stay away from it, noted Dr. Len Horovitz, a pulmonary specialist at Lenox Hill Hospital in New York.

As for cigarette smoke, Horovitz told Healthline that if you can smell it, youre probably too close.

According to the National Institutes of Health, secondhand smoke can stay in the air for several hours and travel up to 20 feet.

Horovitz says that vaping and smoking are closer to singing or shouting than speaking in terms of how far exhaled novel coronavirus droplets can travel.

In one well-documented case, dozens of members of a choir group in Washington state contracted COVID-19 after a practice session.

The act of singing, itself, might have contributed to transmission through emission of aerosols, which is affected by loudness of vocalization, the Centers for Disease Control and Prevention (CDC) noted.

The pursed-lip, forced exhalation of smoking can cause smoke to travel at least twice as far as regular talking, said Horovitz.

Vapers are particularly susceptible to spreading SARS-CoV-2 to each other because vaping is often a group activity, said Wold.

Because most users view vaping as less harmful than cigarette smoking, many tend to vape indoors where they would not smoke, Dr. Joi Lucas, a pediatric pulmonologist at Lakeland Regional Health Medical Center in Florida, told Healthline.

However, research has shown that the highest risk of novel coronavirus transmission is in indoor spaces.

People who vape are more likely to transmit COVID-19, said Lucas. Not only is it dangerous to vapers, but its dangerous to those in proximity to vapers or those who walk through those vaporized droplets.

Smokers and vapers are believed to be at especially high risk for contracting COVID-19, making coming into contact with tobacco smoke or vaping clouds even riskier.

A recent Stanford University study, for example, found that teens and young adults who have used e-cigarettes were five times more likely to be diagnosed with COVID-19 than nonusers.

Those who used both e-cigarettes and conventional cigarettes in the previous 30 days were almost seven times more likely to be diagnosed with the disease.

X-rays of lung damage caused by vaping and COVID-19 can look very similar, said Horovitz, and that damage can make the lungs more vulnerable. Vapers are probably more susceptible to getting COVID because they have more epithelial damage that allows more inroads of the virus.

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Can Secondhand Smoke Transmit the Novel Coronavirus? - Healthline

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Letters to the Editor: Beginning our ‘Fantastic Voyage’; Citizenship issues and the Presidency; In defense of flag and country – Santa Maria Times

§ August 18th, 2020 § Filed under Nano Medicine Comments Off on Letters to the Editor: Beginning our ‘Fantastic Voyage’; Citizenship issues and the Presidency; In defense of flag and country – Santa Maria Times

He has resurrected those claims against vice presidential candidate, Kamala Harris, insisting that, although born in Oakland, her non-citizen parents do not satisfy the Constitutional requirement that candidates for President be "natural born citizens."

It should be noted that concerns were not raised about the qualification of the late Sen. John McCain, who was born to citizen parents in Panama, or to Sen. Ted Cruz, who was born in Canada with one parent being a Cuban national.

The "natural born citizen" requirement was inserted by political enemies of Alexander Hamilton who was born in the West Indies. Precedent has dictated that Presidential candidates need not have been born in the United States so long as at least one of their parents is a U.S. citizen and that a candidate's parents need not be U.S. citizens so long as he or she was born in the United States. A question worth pondering is: are the many thousands of children fathered by U.S. servicemen stationed around the world, by definition, U.S. citizens?

Robert Hoffman

Santa Maria

Generally I let writers express their opinion and if I disagree, let it go as freedom of speech. The kneeling athletes got my attention, as I've always felt kneeling was a form of worship, like Tebow did before playing a game. To kneel instead of stand, and with hand over heart, is a form of disrespect to what our flag stands for.

The flag with its red, white and blue isn't just a piece of material but history being displayed. The red stripes represent the valor of those who died for us, the white is for our liberty we take for granted, the blue is representing justice and the stars, our states' independence.

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Letters to the Editor: Beginning our 'Fantastic Voyage'; Citizenship issues and the Presidency; In defense of flag and country - Santa Maria Times

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