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Global Nanomedicines Market 2026 : Focus Their Efforts On Product Innovation In Order To Attract New Consumers – Chronicle 99

§ February 22nd, 2020 § Filed under Nano Medicine Comments Off on Global Nanomedicines Market 2026 : Focus Their Efforts On Product Innovation In Order To Attract New Consumers – Chronicle 99

The Nanomedicines market was valued at XX Million US$ in 2018 and is projected to reach XX Million US$ by 2024, at a CAGR of XX% during the forecast period. In this study, 2018 has been considered as the base year and 2019 to 2024 as the forecast period to estimate the market size for Nanomedicines.Global Nanomedicines industry market professional research 2014-2024, is a report which provides the details about industry overview, industry chain, market size (sales, revenue, and growth rate), gross margin, major manufacturers, development trends and forecast.

To access the sample report of the Nanomedicines market visit at: https://www.orbisresearch.com/contacts/request-sample/4303185

Key players in global Nanomedicines market include:

AbbottGE HealthcareJohnson & JohnsonMerckPfizerCombiMatrixCelgeneMallinckrodtSigma-Tau PharmaceuticalsTeva PharmaceuticalNanosphereUCB SA

Market segmentation, by product types:

NanoparticlesNanoshellsNanotubesNanodevicesOthers

Market segmentation, by applications:

HospitalsClinicsResearch Institute

Market segmentation, by regions:

North America (United States, Canada)Europe (Germany, France, UK, Italy, Russia, Spain)Asia Pacific (China, Japan, Korea, India, Australia, New Zealand)Middle East & Africa (Middle East, Africa)Latin America (Mexico, Brazil, C. America, Chile, Peru, Colombia)

Click to access full pages https://www.orbisresearch.com/reports/index/global-nanomedicines-market-research-report-2020-segment-by-key-companies-countries-types-applications-and-forecast-2021-to-2026

The report can answer the following questions:1. North America, Europe, Asia Pacific, Middle East & Africa, Latin America market size (sales, revenue and growth rate) of Nanomedicines industry.2. Global major manufacturers operating situation (sales, revenue, growth rate and gross margin) of Nanomedicines industry.3. Global major countries (United States, Canada, Germany, France, UK, Italy, Russia, Spain, China, Japan, Korea, India, Australia, New Zealand, Southeast Asia, Middle East, Africa, Mexico, Brazil, C. America, Chile, Peru, Colombia) market size (sales, revenue and growth rate) of Nanomedicines industry.4. Different types and applications of Nanomedicines industry, market share of each type and application by revenue.5. Global market size (sales, revenue) forecast by regions and countries from 2019 to 2024 of Nanomedicines industry.6. Upstream raw materials and manufacturing equipment, industry chain analysis of Nanomedicines industry.7. SWOT analysis of Nanomedicines industry.8. New Project Investment Feasibility Analysis of Nanomedicines industry.

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About Us:Orbis Research (orbisresearch.com) is a single point aid for all your market research requirements. We have vast database of reports from the leading publishers and authors across the globe. We specialize in delivering customised reports as per the requirements of our clients. We have complete information about our publishers and hence are sure about the accuracy of the industries and verticals of their specialisation. This helps our clients to map their needs and we produce the perfect required market research study for our clients.

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Sunway University Researchers Recognised with the Vice-Chancellor’s Research Award – QS WOW News

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on Sunway University Researchers Recognised with the Vice-Chancellor’s Research Award – QS WOW News

In its aim towards becoming the countrys international education hub, Sunway University is moving forward in its pursuit of excellence not only in academia but also through innovative research.

At the end of last year, four Sunway University researchers were recognised with the Vice-Chancellors Research Award. The recipients were; Associate Professor Dr Yong Min Hooi from the Department of Psychology who received the Special Research Award, Professor Saidur Rahman of the Research Centre for Nano-Materials and Energy Technology with the Award for Achievement in Research, Dr Ayaz Anwar of the Department of Biological Sciences and Dr Hassanudin Mohd Thas Thaker from the Department of Economics and Finance who each received the Award for Achievement in Research for Early Career Researcher.

Associate Professor Dr Yong Min Hoois research focusses on ageing, specifically, executive function and social cognition in older adults. Dr Yong received the Long-Term Research Grant Scheme (LRGS) from the Ministry of Education Malaysia, amounting to RM2.47 million for a 5-year research on Successful ageing: Evidence-based interventions to delay ageing-related decline. This is first single largest grant received in the history of Sunway University. The five-year term from 1 December 2019, scheduled to be completed by 30 November 2024, is categorised under the Aging cluster within Health research cluster and governed under the Sunway Universitys Research Ethics Committee.

Dr Yong previously received various grants from the Newton-Ungku Omar Fund from British Council and the Malaysian Industry-Government Group for High Technology (MIGHT), Arts and Humanities Research Council UK, and Fundamental Research Grant Scheme (FRGS) from Ministry of Higher Education.

Professor Saidur Rahman is Head of the Research Centre for Nano-Materials and Energy Technology. His research focus is in the area of emerging nano-materials, applications in harvesting and storing of solar energy. He has been recognised as a highly cited researcher, listed as the top 1% researchers for most cited documents in his research field of nanofluids for the last 6 years (2014-2019).

Dr Ayaz Anwars current research projects focus on nanomedicine and medicinal chemistry for the development of antimicrobial chemotherapy. His research on silver nanoparticles targeting brain eating amoeba gained international coverage and was featured in the New York Times.

Dr Hassanudin Mohd Thas Thaker research focus in Islamic banking and finance, real estate finance, financial markets, derivatives, and economics has been recognised internationally, earning him the Emerald Literati award in 2016.

Sunway University has 9 research centres and one research group under its roof where research across various fields of study is encouraged.

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Scopio Labs Enhances Digital Cytology Through The Launch Of Automated Imaging And Solutions For Veterinary Market – Pulse 2.0

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on Scopio Labs Enhances Digital Cytology Through The Launch Of Automated Imaging And Solutions For Veterinary Market – Pulse 2.0

Scopio Labs a company dedicated to advancing digital microscopy announced that the ScopioVet Digital Cytology System (already installed in dozens of veterinary clinics) is now available commercially throughout the United States and Canada. And ScopioVet is the first true end-to-end solution for veterinary digital cytology, consisting of Scopios proprietary microscopy imaging system an intuitive pathology consultation service and powerful AI tools that automate routine diagnostic tests. Plus ScopioVet enables veterinary clinics to scan and send cytology and hematology cases to a global network of clinical pathologists who provide round-the-clock analysis, within one hour.

The diagnostic practice of cytology and hematology is designed to be a less invasive and significantly faster option than histology, said Asher Fink, Veterinary Business Head and VP of Business Development for Scopio Labs. However, when veterinarians and pet parents wait several days for results to come back, as is the case in most veterinary practices worldwide, the value of cytology is reduced. ScopioVet corrects this dynamic, by providing results in less than an hour, unlocking the true value of cytology and improving the standard of care so veterinarians can deliver exceptional service with improved outcomes.

Scopio Labs proprietary digital microscopy platform scans microscope slides at 100X equivalent magnification and makes it the highest resolution and quality system in the world. And this resolution level is essential for analyzing the sample types generated at the veterinary point of care such as blood, fine needle aspirates and body fluids.

To provide a conclusive diagnosis for the range of sample types our customers process, 100X magnification is the gold standard, added Natalie Hoepp, DVM, MS, DACVP, Medical Director at Scopio Labs. Anything less will leave the clinical pathologist in doubt due to lack of finer microscopic detail, or worse they may not be able to accurately identify certain microscopic features at all. This will not serve the veterinarian or the patient, and creates diagnostic liability for our veterinary customers. The clear superiority of Scopios technology is one of the many reasons I chose to join their vision for the advancement of digital clinical pathology in veterinary medicine.

Scopio Labs also announced it has implemented powerful features that enable a seamless and comprehensive workflow at the veterinary point of care. For example, ScopioVet has a three slides tray, which allows for easy scanning of cases with more slides. And the service also includes an in-app pathologist chat feature, preferred pathologist routing, and immediate scan streaming which allows pathologists to review scans right away instead of waiting for them to finish uploading thus supporting a rapid turnaround time.

Scopio Labs is also developing artificial intelligence tools that support increased accuracy and efficiency. The first tool to launch now undergoing clinical validation is the platelet count estimate, which saves valuable technician time by quickly and accurately identifying platelets in peripheral blood smears and calculating volume per microliter.

Were bringing significant improvements to the veterinary workflow simply by digitizing the once-analog process of reviewing samples under a manual microscope, explained Itai Hayut, CEO of Scopio Labs. However, our offering only begins there. We have also been developing cutting edge AI models for various use cases in human medicine that are now in various stages of clinical validation. Because the biology is similar, we are able to adjust this AI infrastructure to veterinary samples. Our breakthrough diagnostic platform for veterinary medicine incorporates both AI and remote connectivity to drive the field forward. Veterinary diagnostics is changing rapidly, and were excited to be a part of it.

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The Photograph and Premature come from two different traditions of black love in the movies – The Undefeated

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on The Photograph and Premature come from two different traditions of black love in the movies – The Undefeated

If youre looking for black romance onscreen, you first have to ask: which kind?

Two films released within a week of each other, The Photograph and Premature, exemplify two paths of black cinematic romance that have emerged since a mini golden age of onscreen black love in the late 90s and early 2000s.

Back then, it was impossible to miss the Black Love Brat Pack: mainstream, studio-backed offerings from Theodore Witcher (Love Jones), Gina Prince-Bythewood (Love & Basketball), Malcolm D. Lee (The Best Man), and Rick Famuyiwa (The Wood, Brown Sugar). These films formed a contemporary canon, and launched the careers of a set of actors who became synonymous with the genre, especially Sanaa Lathan, Nia Long, Taye Diggs, Morris Chestnut, Gabrielle Union, and Regina Hall. Their films became pop culture touchstones: endlessly referenced and rewatched, just like the A Different World reruns that used to dominate Nick at Nite.

(Want to launch a grenade at a house party? Try saying Love Jones wasnt actually a good movie, stand back, and watch the argumentative chaos follow.)

Offerings from the Black Love Brat Pack began to thin in the mid-2000s, before a mini-revival of sequels, along with Lees adaptation of the Steve Harvey dating advice book, Think Like a Man, reinvigorated the genre.

What filled the space left by those films? A lot of contemplative, experimental indies, and the web series put forth by Numa Perrier and Dennis Dortchs Black & Sexy TV, an outfit that produced and distributed Hello Cupid, The Number, and The Couple. They were an instrumental part of a black web series boom that also included Issa Raes The Misadventures of Awkward Black Girl.

In 2008, around the same time as Black & Sexy began its ascent, Barry Jenkins released Medicine for Melancholy, which starred Wyatt Cenac and Tracey Heggins as a San Francisco couple coming together against a backdrop of gentrification. Ava DuVernay premiered I Will Follow, a drama about a woman sorting out her life and relationships as she cares for a sick aunt, in 2011. Her star began to rise, especially when DuVernay became the first black woman to win the best director prize at the Sundance film festival for Middle of Nowhere, which focused on the life of a woman whose partner is incarcerated. Dee Rees feature debut, Pariah, came out in 2011, and Terence Nance followed with An Oversimplification of Her Beauty, a weird, heartfelt drama that combined animation and live action, in 2012.

Michael Block (LaKeith Stanfield, left) and Mae Morton (Issa Rae, right) in The Photograph, which was written and directed by Stella Meghie.

Emily Aragones/Universal Pictures

The Black Love Brat Pack dramas and comedies focused on the romantic lives of professional people and their romantic entanglements. It was a small circle. The directors would talk to each other, which is how Prince-Bythewood ended up casting Hall in Love & Basketball she saw her in The Best Man and called Lee. While the Black Love Brat Pack films were lighthearted and largely divorced from larger social issues, the indies often were not. They incorporated themes of displacement and mass incarceration and explorations of queer sexuality. Without the big promotional budgets that come with wide-release films, they often found their audiences through streaming services and word-of-mouth. What emerged felt new and different: a spate of filmmakers introducing work, often made with microscopic budgets, that thrived on creating atmospheres of connection and intimacy.

In The Photograph, her first turn as a romantic lead in a studio drama, Rae appeared to be pulling from both traditions. In her 2016 memoir, Rae wrote about her admiration for Prince-Bythewood and Love & Basketball and how it inspired her to write her own movie, called Judged Cover. She wrote to Prince-Bythewood to tell the director that she watched Love & Basketball daily for inspiration. Meanwhile, her co-star in The Photograph, LaKeith Stanfield, had emerged as a poster boy of the indie film set, thanks to turns in Short Term 12, Sorry to Bother You, and Get Out.

The Photograph is very much a millennial film that hearkens back to the glory days of the Black Love Brat Pack. Its about two normal black people, as Rae calls them: middle-class professionals living in New York. Theres no backdrop of poverty, or stop-and-frisk, or other forms of structural racism coloring the lives of Raes and Stanfields characters.

On Friday, IFC films releases Premature, a coming-of-age romance shot in 16mm that harkens back to films such as Shes Gotta Have It (1986), Just Another Girl on the I.R.T. (1992), Kids (1995), and Raising Victor Vargas (2002). The film, which won the Film Independent Spirit Award for Someone to Watch, will have a theatrical run in New York and Los Angeles, and is also available to stream. Set in gentrifying modern-day Harlem, playwright and poet Zora Howard, who co-wrote the movie, stars as Ayanna, a recent high school graduate in the summer before she starts life as a freshman at Bucknell. She falls for the slightly older Isaiah (Joshua Boone), a producer and composer, and who gently persists in pursuing her after meeting Ayanna during a pickup game at Rucker Park.

I enjoyed Premature enormously. Its a thoughtful portrait of what its like to exist in the space of early adulthood while experiencing an intoxicating first love. Howard, in her first feature performance, imbues Ayanna with a wild, hungry, sexuality that also can quickly turn bashful and insecure. She refuses to say much to Isaiah when he first expresses interest. He sits on a playground swing next to her and introduces himself, and Ayanna simply walks off without revealing her name. Then hes chasing after her down the street days later, as Ayanna hauls a bag of laundry back to the apartment she shares with her mother.

Joshua Boone (left) as Isaiah and Zora Howard (right) as Ayanna in Premature.

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Cinematographer Laura Valladeos choices feel rich and revelatory, especially in the sex scenes. This is fully Ayannas story, told from her point of view. She practically devours Isaiah when they finally get some time alone, and when he slows things down, she shrinks, chastened, and sits covering herself as Isaiah picks out a record to play.

Its a masterful portrayal of the appearance of confidence that comes with being 17, of being talented and smart and yet unaware of what you dont know. Ayanna, having witnessed her mothers disinterested approach to come-and-go suitors, realizes that she and Isaiah have something special, and she tries desperately to protect it, even as their age difference begins to present fissures. Shes got a lot in common with the titular character in Juno, and with Carey Mulligan in An Education, teenage characters known for their emotional precocity. The story crests with a pregnancy and an abortion. But the film never becomes an issue film. Premature is not really an abortion story, but one about a girl finding her voice, and learning to put herself first.

Whats frustrating, ultimately, when it comes to the way we consume black romance, is how much loveliness remains hidden by contrasts in distribution. Premature deserves as wide a release and as much attention as The Photograph, especially when a new, millennial Black Love Brat Pack has yet to emerge. Perhaps thats because these types of indies are where black love stories are headed. Wouldnt it be nice if studios took heed?

Soraya Nadia McDonald is the culture critic for The Undefeated. She writes about pop culture, fashion, the arts, and literature. She's based in Brooklyn.

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Zinc Sulfate Heptahydrate Market Increasing Demand with Leading Player, Comprehensive Analysis, Forecast 2026| China Bohigh, IRO Group, Noah…

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on Zinc Sulfate Heptahydrate Market Increasing Demand with Leading Player, Comprehensive Analysis, Forecast 2026| China Bohigh, IRO Group, Noah…

Global Zinc Sulfate Heptahydrate Market Latest Research Report 2020

Growth forecast on Zinc Sulfate Heptahydrate Market size | Industry Segment by Applications (Zinc Salt, Electrolytic Plating, Fibrogenesis, Fertilizer, Pharmaceuticals, Feed, Others), by Type (Chemical Fiber Grade, Food Grade, Agricultural Grade, Medicine Grade, Feed Grade, Technical Grade), Regional Outlook, Market Demand, Latest Trends, Zinc Sulfate Heptahydrate Industry Share & Revenue by Manufacturers, Company Profiles, Growth Forecasts 2026.

The report on the global Zinc Sulfate Heptahydrate industry is just the resource that players need to strengthen their overall growth and establish a strong position in their business. It is a compilation of detailed, accurate research studies that provide in-depth analysis on critical subjects of the global Zinc Sulfate Heptahydrate industry such as consumption, revenue, sales, production, trends, opportunities, geographic expansion, competition, segmentation, growth drivers, and challenges. As part of geographic analysis of the global Zinc Sulfate Heptahydrate industry, the report digs deep into the growth of key regions and countries, including but not limited to North America, the US, Europe, the UK, Germany, France, Asia Pacific, China, and the MEA. All of the geographies are comprehensively studied on the basis of share, consumption, production, future growth potential, CAGR, and many other parameters.

The global Zinc Sulfate Heptahydratemarket is valued at xx million US$ in 2020 is expected to reach xx million US$ by the end of 2026, growing at a CAGR of xx% during 2021-2026.

Download Sample Copy of this Zinc Sulfate Heptahydrate Market Report: https://www.qyresearch.com/sample-form/form/1523523/global-zinc-sulfate-heptahydrate-market

The research report is broken down into chapters, which are introduced by the executive summary. Its the introductory part of the chapter, which includes details about global market figures, both historical and estimates. The executive summary also provides a brief about the segments and the reasons for the progress or decline during the forecast period. The insightful research report on the global Zinc Sulfate Heptahydrate market includes Porters five forces analysis and SWOT analysis to understand the factors impacting consumer and supplier behavior.

Global Zinc Sulfate Heptahydrate Market: Competitive Landscape

This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2020.

This report covers leading companies associated in Zinc Sulfate Heptahydrate market:

China Bohigh, IRO Group, Noah Technologies, Sulfozyme Agro India, Kemphar International, G.G. Manufacturer, Uniwin Chemical, Shepherd Chemical, Mistral Industrial Chemicals, Shri Ram Agro Chemicals, Chandigarh Chemicals, Akash Purochem, Prabhat Fertilizer & Chemical Works, Spring Chemical Industry, Xiangtan Fenghe Biotechnology, Tianjin Xinxin Chemical Factory, HUBEI HAIYAN KEJI YOU, Henan Xintai Water Processing Materials, Changning City Huaxing Metallurgical Industrial, Paras, RUNZI, etc.

Market Segment Analysis

The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth.

Segment by Type:

Chemical Fiber GradeFood GradeAgricultural GradeMedicine GradeFeed GradeTechnical Grade

Segment by Application:

Zinc SaltElectrolytic PlatingFibrogenesisFertilizerPharmaceuticalsFeedOthers

Global Zinc Sulfate Heptahydrate Market: Regional Analysis

The report offers in-depth assessment of the growth and other aspects of the Zinc Sulfate Heptahydrate market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America.

The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region.

Key Benefits for Stakeholders

Table Of Content

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Sunburn The morning read of what’s hot in Florida politics 2.20.20 – Florida Politics

§ February 20th, 2020 § Filed under Nano Medicine Comments Off on Sunburn The morning read of what’s hot in Florida politics 2.20.20 – Florida Politics

Six Democratic presidential hopefuls met on the debate stage in Las Vegas, but it was the newcomer, former New York Mayor Mike Bloomberg, who received the most attention, and none of it positive. Here are some key takeaways from the debate.

The $60 billion punching bag

Bloomberg was the object of scorn, ridicule and contempt. And that was just in the first five minutes of the debate.

With all candidates flashing heat, a measure of the urgency they feel to survive in what is becoming an increasingly bitter nomination fight, the attacks focused on Bloomberg were a clear measure of his perceived strength. He has spent more than $400 million so far on advertising that in turn has given him strong standing in state and national polls.

Sen. Bernie Sanders recalled Bloombergs support of stop-and-frisk policing targeting minorities. Sen. Elizabeth Warren recalled how Bloomberg had mocked women for being horse-faced and fat and compared him to Trump. Sen. Amy Klobuchar quipped that I dont think you look at Donald Trump and say I think we need someone richer in the White House. Former Vice President Joe Biden said Bloomberg condoned racist police practices, and Pete Buttigieg, the former mayor of South Bend, Indiana, said Bloomberg was trying to buy out the Democratic Party.

But his biggest struggle came when Warren hammered him over allegations of sexism and mistreatment of women in his company.

Bloomberg attempted to defend his record and deflect the attacks on him by turning them into attacks on President Donald Trump. And he effectively raised questions about whether Americans would embrace a socialist like Sanders.

But the glare was harsh, and the attacks landed with force.

Even if you are worth $60 billion it is hard to win a 5-on-1 fight.

Not the era of good feelings

For eight debates, the Democrats largely tiptoed around disagreements except for desultory disputes about health care policies. But on Wednesday night, everyone came with sharp elbows.

It was almost impossible to keep track of the fights. Buttigieg and Klobuchar tussled over experience and the Minnesota senator forgetting the name of Mexicos president. Buttigieg and Sanders argued about the Vermont senators big-ticket plans and refusal to release his full medical records. Warren clashed with Buttigieg and Klobuchar over their health care plans. And everyone piled onto Bloomberg.

The former New York mayor was the only candidate who didnt really go on the attack, other than the occasional swipe at the self-declared socialist Sanders.

In the end, that dynamic may again benefit Sanders, who leads in the polls and is watching his rivals spend most of their energy tearing each other down rather than targeting him.

Return of Warren the fighter

Warren rose to prominence in the Democratic field with a fighting spirit that defined the early months of her campaign. But her disappointing showings in Iowa and New Hampshire left her campaign struggling.

On Wednesday, she decided to get back into the fight.

She slammed Bloomberg that was no surprise as shes been an antagonist of billionaires playing in politics for years. But Warren also attacked Klobuchar, saying her health care plan was just a Post-it note. She accused Buttigieg of being in debt to his rich campaign supporters and having a health care plan that was just a PowerPoint designed by his consultants. She slammed fellow liberal Sanders, accusing him of letting his supporters trash anyone with a plan.

But it was her prosecutorial approach to Bloomberg over his companys treatment of women that stood out.

Whatever happens on Saturday, and beyond, Warren regained her fighting voice.

The generational divide

Buttigieg, who finished in the top two in Iowa and New Hampshire with Sanders, reserved some of his harshest criticism for Sanders, a man 40 years his elder.

He warned that Democrats could wake up after more than a dozen states vote on Super Tuesday on March 3 and have only Bloomberg and Sanders left on the ballot. He then quipped that the party may want to nominate someone who is actually a Democrat.

The crowd inside the Las Vegas casino hadnt yet finished chuckling and hooting when he continued by saying Sanders wants to burn this party down and Bloomberg wants to buy this party out.

Sanders, a senator from Vermont and avowed democratic socialist, responded by saying that Buttigiegs campaign has been too reliant on billionaire big donors, touching off another intense exchange.

Their back and forth continued through criticism of Sanders supporters who have frequently been accused of bullying behavior online. Sanders said he personally had denounced such behavior. This prompted Buttigieg to say he believed the senator but, What it is it about your campaign in particular that seems to be motivating this type of behavior?

On this night, Buttigieg had the most at stake, with Sanders standing in Nevada polls well ahead of the man who has run even with him in the first two contests.

But Sanders did nothing likely to undermine his standing as the leading candidate so far.

Does Klobentum continue?

The last debate was rocket fuel for Klobuchar. Her strong performance vaulted her to a third-place finish in New Hampshire and onto Nevada. But it may be hard for lightning to strike twice.

The Minnesota senator often got drowned out in the high-octane bickering Wednesday, or pulled down into the mud. At one point she pulled from her supply of ready quips, saying of Sanders and Bloomberg as they argued over capitalism that there is a boxing rematch in Vegas on Saturday and these guys should go down there.

The most damaging exchange was between Klobuchar and Buttigieg, who have tangled before. Asked about her embarrassing gaffe in forgetting the name of Mexicos president, she had to fend off Buttigieg, who claimed it disproved her argument that Washington has prepared her to be president. She also alternately scrapped with and aligned with Warren.

Are you calling me dumb? Klobuchar asked Buttigieg incredulously. Later, she added, I wish everyone was as perfect as you, Pete.

A little over a week ago in New Hampshire, Klobuchar clearly stood out. This time was much harder as everyone battled for survival.

Did Biden revise his campaign?

Another candidate in need of a big night to reverse perceptions that his campaign was struggling was Biden.

For a good portion of the debate, he receded. He joined in the attacks on Bloomberg, but largely avoided some of the more testy exchanges.

When Warren said that Biden was in the pocket of Republican Mitch McConnell, the Senate majority leader, Biden fought back. He also tried to return to his Middle Class Joe biography about his familys financial struggles.

He did not offer voters any new rationale for voting for him.

Bloomberg bombs in debate debut via POLITICO He rolled his eyes when Elizabeth Warren pressed him to release women at his company from non-disclosure agreements related to alleged mistreatment. He suggested he cant simply use TurboTax, like many Americans, to crunch his billions in order to speed up the release of his tax returns. He pouted when moderators didnt return to him on health care, muttering, What am I, chicken liver? Bloomberg spent the past 10 weeks flooding the airwaves with ads, racking up endorsements and climbing into contention ahead of his Super Tuesday debut. And in two hours Wednesday night, he risked losing those swift gains as he stumbled through his first nationally televised primary debate.He was rusty. He was testy. He was out of touch. And, for a candidate often shielded by the scripted one-liners of killer campaign advisers, he was on his own unable to hide his peevish demeanor and unable to portray himself, as his campaign has tried to do, as the clear choice to stop Bernie Sanders and beat Trump.

Loathing in Las Vegas: Amy and Petes resentment boils over viaElena Schneider of POLITICO Klobuchar made sure there would be no post-debate handshake with Pete Buttigieg. After a series of cutting exchanges during Wednesdays presidential debate, Klobuchar cut around Buttigieg without a glance in his direction as they stepped away from their neighboring podiums following Wednesdays Democratic showdown.

Pete Buttigieg and Amy Klobuchar are both hawking middle-of-the-road, tell-it-like-it-is personas.

The hostility building between the two Midwestern Democratsburst dramatically into the open in Nevada, as they clashed repeatedly on the debate stage and tried to slash the momentum out of each others campaigns. Klobuchar and Buttigieg have fought before over their experience and their political records in past debates but the feud took a deeply personal turn.

He Said, She Said colors in the presidential primary On the new episode of He Said, She Said, Michelle and I start with a couple of recaps: our current bets on PredictIt and our Valentines Day activities.

Moving on to politics, pollster Steve Vancore gives his predictions for Floridas Democratic presidential primary and talks about President Donald Trump at the Daytona 500. Then Vancore also breaks down our increasingly siloed lives. If he had to place a PredictIt bet, Vancore says Bernie Sanders is a buy and explains why Joe Biden would stay in the race through South Carolina and Super Tuesday.

Michelle and I debate the Democratic field and examine the flaws of a Sanders nomination.

Adam Goodman joins the pod to give a deep dive into the various paths the Democratic primary could take, drawing parallels from the current presidential race to the 2018 gubernatorial race between Ron DeSantis and Andrew Gillum. Goodman explains why he would want to see Bernie Sanders go head-to-head with Trump. I disagree.

We also talk about what a Bloomberg nomination could mean for the Democrats. Goodman says it will feed into Trumps class warfare narrative.

To subscribe and listen, visit Apple Podcasts, Google Play and Stitcher.

TODAYS SUNRISE

The House will be voting today to require parental consent for abortions and to strip the Florida Coalition Against Domestic Violence of their exclusive contract with the state.

Also, on todays Sunrise:

A federal appeals court in Atlanta rules against the state in a challenge over voting rights for former felons. The Governors office says theyll appeal.

President of New College, Donal OShea, comes to The Capitol at an existential moment. Hes trying to stop a bill that calls for his University to become a branch campus of Florida State University.

Crime survivors gather at The Capitol, calling for major changes in the criminal justice system. They want more rehabilitation and less incarceration to break the cycle of violence.

Vancore gives his take on Floridas presidential preference primary and the scandal at the Florida Coalition Against Domestic Violence.

The continuing adventures of Florida Man who has a severe drug problem.

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SITUATIONAL AWARENESS

@NateSilver538: Average projected delegates through Super Tuesday: Sanders 608 (41% of delegates thru March 3) [Mike] Bloomberg 273 (18%) Biden 270 (18%) [Pete] Buttigieg 157 (10%) [Elizabeth] Warren 127 (8%) [Amy] Klobuchar 55 (4%).

@FlaFarmBureau: We hope @chucktodd asks @MikeBloomberg to describe how we should be hedging the corn futures market while calibrating a variable rate fertilizer spreader and planting crops on laser leveled fields with a GPS controlled auto-steer tractor. Well take notes.

@maxwelltani: After 2016, people said media needs to do a better job going to real America to cover the issues Americans actually care about. So its interesting to see media spend so much time discussing Bernie supporters online behavior, an issue primarily affecting media and political pros

@MattGaetz: Fifty years ago, a gay man or woman couldnt work in the intelligence community. Today President Trump is appointing an openly gay man to serve as Acting Director of National Intelligence. Congratulations, Ambassador

@TomLeeFL: E-Verify is either mandatory for all or its not mandatory.

@fineout: A Senate panel today spent less than 5 minutes to take up and vote out on a party-line vote a proposed constitutional amendment that would make it harder for future amendments to make ballot. This was the first time this proposed resolution had even been heard in Senate

@CarlosGSmith: No acknowledgment that his actions were homophobic or hurtful. No direct apology to the LGBTQ community or to his constituents. @ALJacquet clearly does not understand the gravity of his words or the harm they cause LGBTQ Floridians. Its sad, really.

@Daniel_Sweeney: Ah, its that time of the legislative session in Tallahassee when multiple bills on a subject havent quite gotten over the hill, so a new bill suddenly emerges and lawmakers all say, well, weve debated many of the parts of this bill, so its had a full hearing.

@ScottFist: Ive seen a lot of really, really good, really admirable, political journalists who, once they retire from journalism, explode with releasing their political opinions. Its kinda like holding in a fart for 40 years. And it just doesnt smell good.

Tweet, tweet:

@KarlEtters: Another week. Another body found in a car at a Tallahassee Walmart.

@DanTallahassee: UF alumni association is sending me emails. How did this happen? Perhaps its because the brazen admissions folks at UF still cant get over how I chose FSU the true Harvard of the South over UF because of its proximity to the Capitol and less pretentious student body

Tweet, tweet:

DAYS UNTIL

Nevada caucuses 2; Better Call Saul Season 5 premiers 3; Suits for Session 5; 10th Democratic presidential debate in Charleston 5; The Markup, a nonprofit newsroom covering technology, launches 5; South Carolina Primaries 9; Super Tuesday 12; Last day of 2020 Session (maybe) 22; Floridas presidential primary 26; No Time to Die premiers 46; Florida TaxWatch Spring Board Meeting begins 55; TaxWatch Principal Leadership Awards 56; Florida Chamber Summit on Prosperity and Economic Opportunity 85; Top Gun: Maverick premiers 127; Democratic National Convention in Milwaukee begins 144; Christopher Nolans Tenet premiers 148; 2020 Summer Olympics in Tokyo start 155; Florida primaries for 2020 state legislative/congressional races 180; Republican National Convention begins in Charlotte 186; First Presidential Debate in Indiana 222; First Vice Presidential debate at the University of Utah 230; Second Presidential Debate scheduled at the University of Michigan 238; Third presidential debate at Belmont 245; 2020 General Election 257.

TOP STORY

Mike Pompeos Florida tour included undisclosed stop at The Villages, and the State Department wont say why via Steve Contorno of the Tampa Bay Times Secretary of State Pompeo managed to squeeze in an appearance in Bushnell last month. If Pompeo had a reason for stopping in this city of 3,100 on Jan. 23, he didnt reveal it during his brief remarks at the Sumter County Fairgrounds. After 30 minutes there, his motorcade pulled out of the parking lot and sped away. But, it turns out, he wasnt ready to leave Florida quite yet. From the fairgrounds, Pompeo took an unannounced side trip to The Villages. Although its still not clear why Pompeo ventured to The Villages, the trail of paperwork traced Pompeos movements that day to the doorstep of one of the wealthiest Republican donors in Central Florida: the Morse family.

Mike Pompeo made an unscheduled stop in a major GOP donor during his visit to The Villages.

DATELINE: TALLY

Court: Florida cant bar felons from vote over fines, fees via Bobby Caina Calvan and Curt Anderson of The Associated Press A three-judge panel of the 11th U.S. Circuit Court of Appeals upheld a Tallahassee federal judges preliminary injunction that a state law implementing Amendment 4 amounted to an unfair poll tax that would disenfranchise many of the released felons. In its ruling, the circuit court said the financial requirement punishes those who cannot pay more harshly than those who can and does so by continuing to deny them access to the ballot box. The court added that previous U.S. Supreme Court rulings required it to apply heightened scrutiny in asking whether the requirement violates the Equal Protection Clause of the Fourteenth Amendment as applied to these plaintiffs.

Ron DeSantis bolsters deregulation office Gov. DeSantis penned an executive order in November directing that increased the power of the Office of Fiscal Accountability and Regulatory Reform, Matt Dixon of POLITICO Florida reports. The order called for the Office of Policy and Budget to designate a liaison to OFARR for each area of the budget. DeSantis spokesperson Helen Aguirre Ferr said this week that the memo was to ensure that there was designated personnel in each policy area to get a more thorough organizational review of state regulations.

DeSantis announces $4.8 million grant for ST engineering expansion, project now fully funded via Jim Little of the Pensacola News Journal The expansion project, which calls for building three more hangars and office space for ST Engineering, is expected to bring more than 1,300 jobs to the airport. ST Engineering opened its first maintenance, repair and overhaul, or MRO, hangar at the Pensacola Airport in June 2018. That hangar is expected to employ 400 people when operating at full capacity, putting the number of jobs at the entire facility at more than 1,700 people. At last count in January, ST Engineer had 163 employees at the airport. DeSantis said the ST Engineering expansion would have an impact on the economy of the entire region and would not have happened without many people coming together to support it.

Ron DeSantis announces a major job growth grant for Pensacola Airport.

DeSantis unveils housing loan program for military, veterans DeSantis announced the Salute Our Soldiers Military Loan Program (SOS) for veterans and active-duty military personnel throughout the state. The announcement followed a roundtable to discuss ongoing issues and initiatives that involve Floridas military and veteran population. Joining the Governor were Florida Department of Veterans Affairs (FDVA) Executive Director Danny Burgess and Florida Housing Finance Corporation (Florida Housing) Executive Director Trey Price. Florida Housing will set aside funds to assist over 1,000 veterans and active-duty military members by making the homebuying process easier and more affordable, DeSantis said. More veterans calling Florida home is a great thing for all involved.

Ron DeSantis also unveils a housing loan program to benefit Florida service members and veterans.

Jos Oliva earns praise for Nurse Practitioner of the Day pick House Speaker Olivaselected Donna Bixler for Nurse Practitioner of the Day. Bixler is a family nurse practitioner affiliated with the Internal Medicine division at Southern Medical Group in Tallahassee, where she has practiced since 1998. Oliva earned praise from Floridians Unite for Health Care, both for his continued recognition of APRNs and his support of a bill (HB 607) that would grant independent practice rights to APRNs and physician assistants. The bill has cleared two committees and is awaiting a hearing in the House Health and Human Services Committee, its final stop before the chamber floor.

Congratulations to Donna Bixler, named Nurse Practitioner of the Day.

County RECs back strong E-Verify bill The Republican Party of Florida already passed a resolution in favor of E-Verify requirements for all businesses. Additionally, 16 county Republican Executive Committees have passed measures of their own. Those include Bradford; Duval; Hamilton; Highlands; Indian River; Lake; Leon; Levy; Manatee; Marion; Okeechobee; Palm Beach; Saint Lucie; Sarasota; Volusia; and Walton counties. Floridas economy continues to grow under Republican leadership, and using E-Verify, we will only expand jobs and opportunities for legal workers in our state, said RPOF Chair Joe Gruters. After all, we live in a nation of laws and illegal immigration undermines those laws, threatens public safety in our state, and undercuts wages for Florida workers. It is only right to require employers to follow the rule of law and to ensure that the workers they are hiring are eligible and, in our country, legally.

Amid pay scandal, Floridas domestic violence nonprofit loses support via Mary Ellen Klas and Samantha Gross of the Tampa Bay Times The Florida House took the first step toward severing the special arrangement the state has with the Florida Coalition Against Domestic Violence and advanced a bill to require the agency to face competition. It is only the beginning of the changes ahead for the agency under fire for paying former CEO Tiffany Carr more than $7.5 million over three years as domestic violence victims across the state were denied services. Documents show that Carr was allowed to cash-in more than $5 million of paid time off at the agency that is primarily funded with state and federal taxpayer dollars. The bills are expected to be approved and signed by the Governor before the Session ends.

New College Prez, Sarasota Democrats urge no on university merger plan via Sarah Mueller of Florida Politics Members of the Sarasota County legislative delegation joined New College President OShea in speaking out against the proposal at The Capitol. Republican Sen. Gruters set up the press conference. But Republican members of the delegation were a no-show. I did have some conversations, but at the end of the day, it really was just a mix-up in time, and since everybody was already scheduled, I couldnt make it, and so we just allowed it to continue on, he said. Once that message got back, thats why there was confusion, but it was inadvertent. All the delegation, except for Senate President Bill Galvano, have written a local op-ed article opposing the bill.

Manufactured home bill gets owner, industry backing via Florida Politics A joint announcement from the Federation of Manufactured Homeowners of Florida (FMO) and the Florida Manufactured Housing Association comes after the bills HB 1339 by Rep. Clay Yarborough and SB 998 by Sen. Travis Hutson were altered to add protections for tenants privacy, clarify HOA governance requirements and increase the amount of housing available. Updating to the 40-year-old manufactured home statutes has been a longtime priority for both parties, though they havent always seen eye-to-eye on what those updates should include. Thats led to dead bills in Sessions past.

Pro athlete, other crime victims come to Capitol for annual survivors speak rally via Tori Lynn Schneider of the Tallahassee Democrat Stedman Bailey, a Miramar native, was drafted into the NFL by the St. Louis Rams in 2013. His career was cut short just two years later. I was in the car with my cousin, his 10-year-old son, and 6-year-old daughter and my best friend when our car was shot at over 30 times, Bailey said Wednesday. Two bullets struck me in my head, and my cousin was also shot. Bailey and hundreds of other crime survivors visited the Florida Capitol for the third annual Survivors Speak rally, organized by Crime Survivors for Safety and Justice (CSSJ). Aswad Thomas, its managing director, announced his groups two biggest priorities: Housing and job protections for survivors of crime and criminal justice reform.

LEGISLATION

House moves forward with tax cut package, would allow tourism tax dollars for water projects via Jim Turner of the News Service of Florida The Ways & Means Committee approved the package (PCB WMC 20-01), which features sales-tax breaks before hurricane season and the new school year, while trimming taxes on commercial leases and cellphones and other communications services. It also calls for increasing a refund on aviation-fuel taxes, eliminating an unused pool of money for professional sports stadiums, expanding a tax-distribution requirement about charter schools, and adding water infrastructure projects to the list of allowed uses for local tourist- development dollars. The proposal is expected to see some changes before the House negotiates with the Senate on a final package.

Tourism industry slams House tax-cut package The tourism industry is vehemently opposed to a provision in the House tax-cut package that would allow local governments to use tourism tax money on local water projects, Matt Dixon of POLITICO Florida reports. After the plan was unveiled, members of the tourism lobby spoke out against the plan, arguing the tax collections are solely for tourism marketing ventures. Republican Rep. Brian Avila, who chairs the committee behind the bill, said clean water would help attract tourism. In the long run, I am 100 percent confident that our vision for the tourist development tax will ultimately have a positive impact on the tourism industry, he said.

House offers tax break to utilities for solar energy via Mary Ellen Klas of the Miami Herald Quietly tucked into the Houses package of tax breaks is a measure that will let Florida Power & Light and other utilities save millions by delaying the date on which it starts paying taxes on dozens of solar energy plants under construction across the state. The issue didnt come up during the tax workshop, but House Speaker Oliva asked for the budget impact of the proposal to be assessed by state economists in December. The provision was added to the bill, and the House Ways and Means Committee approved the language.

Senate President comes out in support of university merger proposal via Florida Politics The merger is one opportunity that could exist that needs to be discussed, he said.Galvano said he met with New College President Donal OShea who was in Tallahassee to lobby lawmakers against voting for the bill. The Senate President says OShea admitted to struggling to boost enrollment.I shared exactly what I thought were some concerns, he said. And he said Look, its been hard for us. Weve had the performance funding and we werent meeting the metrics. Our population was not hitting on some of these points that other universities do. So that put them behind fiscally. Also enrollment has been a challenge for them.

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Sunburn The morning read of what's hot in Florida politics 2.20.20 - Florida Politics

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ERC president ‘optimistic’ UK will stay in ‘irreplaceable’ fund – Times Higher Education (THE)

§ February 20th, 2020 § Filed under Nano Medicine Comments Off on ERC president ‘optimistic’ UK will stay in ‘irreplaceable’ fund – Times Higher Education (THE)

The UK gains benefits from the European Research Council that cannot be replaced, but there is good reason to be optimistic about the nation staying part of the programme despite Brexit, according to the funders new president.

The UK has been the number one [nation] in terms of funding received since the ERC was established in 2007, Mauro Ferrari toldTimes Higher Educationafter taking office last month. But the real benefit is bigger than that, he added.

Perhaps the biggest advantage of them all is that ERC grants strengthen the UKs position as a top destination for non-UK scientists, Professor Ferrari said. Think of all the great people that are in the UK with an ERC grant.

Science is all about people. You need the best people: you need to recruit them, you need to retain them. And I think the ERC has been a great instrument for the UK to do that.

Prestigious ERC grants for outstanding researchers, part of the European Unions wider framework programmes for research, have been described asmini-Nobel prizesand as the Champions League of research.

There is no certainty over whether the UK will seek to, or be allowed to, join the next framework programme, Horizon Europe, as an associated country when it starts in January 2021.

ERC grants are portable, but holders are expected to spend at least 50 per cent of their working time in an EU member state or associated country leading some in the UK to fear that the nation will miss out on attracting world-leading researchers if it does not associate to Horizon Europe.

While the UK will continue to attract and retain science talent, no matter what, because of its history and continuous investment, there is this bit that comes from the international connotation of the ERC that, I think, cannot be replaced, Professor Ferrari said.

His comments came as John Womersley, chief executive of the Science and Technology Facilities Council between 2011 and 2016, warns that there is great risk that the UK may choose not to associate to Horizon Europe.

Writing in THE, Professor Womersley now director-general of the European Spallation Source says that while UK-based researchers are keen to retain access to ERC funding, ministers are less likely to be keen on the two other larger pillars of Horizon Europe, covering challenge-based funding and the new European Innovation Council.

Professor Womersley warns that the EU is unlikely to allow cherry-picking of Horizon Europe, leading him to conclude that the UK was more likely to use the money it would otherwise contribute to the scheme tocreate a UK-based replacement for the ERC.

Asked by THE whether the UK could associate to the ERC, Professor Ferrari said that he cannot speculate on that. Thats the domain of a political negotiation, he said.

But given unanimous sentiment among UK and continental European scientists he had spoken with, he added: I would say there is good reason to be optimistic that some sort of reasonable construct will be reached that allows scientists to do their job in the best possible way.

ProfessorFerrari also discussed the ERCs role in building bridges between blue-sky research and innovation a link where he has personal experience as a pioneer of nanomedicine.

His 40-year academic career in the US began in engineering with a post at the University of California, Berkeley, then changed course following the death of his wife from cancer, after which heentered medical school at the age of 43to fight the disease.

Professor Ferrari retired as chief commercialisation officer at Houston Methodist Research Institute in 2019, but remains an affiliate professor with a lab at the University of Washington in Seattle.

I have returned [to Europe] for this job because I thought it was such an extraordinary and unique opportunity, he said.

The ERC, which evaluates proposals through international panels of leading scientists, is based on the principle that no individual, no agency, no office can actually envisage the future, what are the necessaryworld-changing breakthroughs in all of the fields of science, Professor Ferrari said. So we let scientists tell us.

Although European science is one of the global front-runners, he continued, there is no doubt about the fact that Europe has been lagging behind the United States when it comes to translation of great discoveries into innovation.

Professor Ferrari added that although the ERC by mandate is only doing blue-sky research, it has a role in addressing that by ensuring that research is best friends with innovation. We connect: we make sure our scientists are aware of whats happening in innovation, and make sure people on the innovation side are aware of what leading scientists are doing, he said.

john.morgan@timeshighereducation.com

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ERC president 'optimistic' UK will stay in 'irreplaceable' fund - Times Higher Education (THE)

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Oxford Performance Materials’ OsteoFab 3D Printed PEKK Technology Focus of Study Published in The Spine Journal – OrthoSpineNews

§ February 19th, 2020 § Filed under Nano Medicine Comments Off on Oxford Performance Materials’ OsteoFab 3D Printed PEKK Technology Focus of Study Published in The Spine Journal – OrthoSpineNews

SOUTH WINDSOR, CONN. (PRWEB)FEBRUARY 17, 2020

Oxford Performance Materials, Inc. (OPM), an industry leader in advanced materials science and high-performance additive manufacturing (HPAM), announced today the publication of A Comparative Study of Three Biomaterials in an Ovine Defect Model: A TETRAfuse PEKK Study in The Spine Journal. 1,2,3 This study examined the in vivo material characteristics of polyetheretherketone (PEEK), titanium-coated PEEK, and 3D printed polyetherketoneketone (PEKK) in a sheep model. In comparison with PEEK, the PEKK implants displayed bone ingrowth, no fibrotic tissue formation, a significant increase in bony apposition over time, and a significantly higher push-out strength.

Conventionally, PEEK and Ti-coated PEEK have been used as standard biomaterials for implants like spinal interbody cages, but recent shortcomings in these materials have led to adoption of newer, more innovative technologies. Although PEEK shows an elastic modulus comparable to that of cortical bone, literature has illustrated that it consistently prompts a fibrotic and inflammatory tissue response, preventing it from integrating with host tissue. And while titanium exhibits similar osseointegrative properties when compared to PEKK, it is substantially stiffer than cortical bone and it is radiopaque, which makes bone fusion assessments difficult as the bone/implant interface is often obscured in post-operative imaging. With titanium coated PEEK implants, these drawbacks still exist but with the added risks of delamination of the titanium coating, subsidence, and the generation of wear debris.

The results reported by The Spine Journal were gratifying and support the comparative benefits of 3D printed PEKK implants that we have been hearing from surgeons for some time, now, said Scott DeFelice, CEO. OPMs OsteoFab technology platform is increasingly recognized as a best of solution for CMF and spinal implants, and we will be launching our unique 3D printed suture anchor product in the coming weeks.

3D printed PEKK delivers high mechanical integrity, radiographic visibility, and osseointegration, as well as inherent antibacterial characteristics.4 In this Spine Journal study, PEKK demonstrated a significantly higher push-out force when compared to PEEK at 8 and 16 weeks post-implantation and also had notably greater bone attachment following pushout when compared to PEEK and Ti-coated PEEK. From a histological standpoint, 3D printed PEKK also showed substantial bone growth. Within a 2mm radius of the implant, 3D printed PEKK exhibited the highest bone ongrowth percentage when compared to PEEK and Ti-coated PEEK at both the 8- and 16-week endpoints.

By directly comparing the three implant materials in an in vivo model, the study showed clear evidence of the performance characteristics at the bone-implant interface. In this instance, 3D printed PEKK presented a high propensity for bone-ingrowth, no radiographic interference, and a material structure that allowed for an increase of integration of cancellous bone into the implant. In a clinical scenario, 3D printed PEKK implants could improve the effectiveness of spinal fusion procedures by promoting osseointegration and decreasing the chance of complications associated with PEEK and Ti-coated PEEK.

Since 2013, OPM has been manufacturing patient-specific cranial and facial implant devices that have been distributed world-wide. In addition to over 2,300 craniomaxillofacial implants, OPM has 3D printed over 70,000 OsteoFab implants under a number of 510(k) clearances and just recently entered the sports medicine arena with a soft tissue fixation device. As the pendulum shifts away from traditional material solutions, OsteoFab 3D printed PEKK is proving to be a robust alternative with a rapidly growing user base.

About Oxford Performance Materials, Inc.

Oxford Performance Materials was founded in 2000 to exploit and commercialize the worlds highest performing thermoplastic, PEKK (poly-ether-ketone-ketone). OPMs Materials business has developed a range of proprietary, patented technologies for the synthesis and modification of a range of PAEK polymers that are sold under its OXPEKK brand for biomedical and industrial applications. The Company is a pioneer in 3D printing. OPM Biomedicals OsteoFab technology is in commercial production in numerous orthopedic implant applications, including cranial, facial, spinal, and sports medicine devices. OPM is the first and only company to receive FDA 510(k) clearance to manufacture 3D printed patient-specific polymeric implants and has six 510(k) clearances in its portfolio. OPM Industrial produces 3D printed OXFAB production parts for highly demanding applications in the energy, transportation and semiconductor markets. OXFAB structures offer significant weight, cost, and time-to-market reductions that are defined in a set of specified performance attributes in the exhaustive OPM B-Basis database, developed in conjunction with NASA. For more information, please visit:http://www.oxfordpm.com

Company Contact:Willow JohndrowDirector of Marketing860.656.9442

References1. Cheng, PhD B, Jaffee S, Swink I, Averick, PhD S, Horvath S, Zhukauskas, PhD R et al. A Comparative Study of Three Biomaterials in an Ovine Bone Defect Model: A TETRAfuse PEKK Study. The Spine Journal. 2019. doi: 10.1016/j.spinee.2019.10.0032. RESULTS paragraph from the Study abstract reads: PEKK implants demonstrated bone ingrowth, no radiographic interference, no fibrotic tissue membrane formation, significant increase in bony apposition over time, and significantly higher push-out strength compared to standard PEEK. The PEKK implant displayed bone growth characteristics comparable to Ti-coated PEEK with significant improvements in implant integrity and radiographic properties.3. Note: TETRAfuse is a Registered Trademark of RTI Surgical, Inc. and the tradename for RTIs spinal implants that are additively manufactured by Oxford Performance Materials, Inc. using OPMs proprietary OsteoFab technology platform. TETRAfuse was awarded a 2019 MedTech Breakthrough Award for Best New Technology Solution Orthopedics and a 2018 Spine Technology Award from Orthopedics This Week.4. Wang M, Bhardwaj B, Webster T; Antibacterial properties of PEKK for orthopedic applications. Intl Journal of Nanomedicine. 2017: 12 6471-6476.

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New Discoveries in Human Anatomy – The Scientist

§ February 19th, 2020 § Filed under Nano Medicine Comments Off on New Discoveries in Human Anatomy – The Scientist

In the 16th century, when the study of human anatomy was still in its infancy, curious onlookers would gather in anatomical theaters to catch of a glimpse of public dissections of the dead. In the years since, scientists have carefully mapped the viscera, bones, muscles, nerves, and many other components of our bodies, such that a human corpse no longer holds that same sense of mystery that used to draw crowds.

New discoveries in gross anatomythe study of bodily structures at the macroscopic levelare now rare, and their significance is often overblown, says Paul Neumann, a professor who specializes in the history of medicine and anatomical nomenclature at Dalhousie University. The important discoveries about anatomy, I think, are now coming from studies of tissues and cells.

Over the last decade, there have been a handful of discoveries that have helped overturn previous assumptions and revealed new insights into our anatomy. Whats really interesting and exciting about almost all of the new studies is the illustration of the power of new [microscopy and imaging] technologies to give deeper insight, saysTom Gillingwater, a professor of anatomy at the University of Edinburgh in the UK. I would guess that many of these discoveries are the start, rather than the end, of a developing view of the human body.

Here is a sampling of some of those discoveries.

The lymphatic system, a body-wide network of vessels that drains fluids and removes waste from tissues and organs, was long-believed to be absent from the brain. Early reports of lymphatic vessels in the meninges, the membrane coating the brain, date as far back as the 18th centurybut these findings were met with skepticism. Only recently has this view been overturned, after a 2015 report of lymphatic vessels in mouse meninges and the 2012 discovery of the so-called glymphatic system, an interconnected network of glial cells that facilitates the circulation of fluid throughout mouse brains. In 2017, neuroimaging work revealed evidence for such lymphatic vessels in human meninges.

In 2018, researchers reported that the space between cells was a collagen-lined, fluid-filled network, which they dubbed the interstitium. They proposed that this finding, which emerged from close examinations of tissue from patients bile ducts, bladders, digestive tracts, and skin, may help scientists better understand how tumors spread through the body. The team also called the interstitium a newly-discovered organ, but many dismissed this claim. Most biologists would be reticent to put the moniker of an organ on microscopic uneven spaces between tissues that contain fluid, Anirban Maitra, a pathologist at the University of Texas MD Anderson Center, told The Scientistlast year.

Until recently, the prevailing view among scientists was that the mesentery, the large, fan-like sheet of tissue that holds our intestines in place, consisted of multiple fragments. In 2016, after examining the mesentery of both cadavers and patients undergoing surgery, a team of researchers concluded that the mesentery was actually a single unit. This wasnt the first time the mesentery was described as continuousin one of the first depictions of the structure, Leonardo da Vinci also portrayed it in this way. But in the 2016 paper, the scientists argued that its continuity should qualify the mesentery as an organ. As with the interstitium, however, other experts have objected to this claim. In both of these cases, there seems to have been a misunderstanding of what the term organ means, Neumann says.

laurie okeefe

In January 2019, scientists described a previously unknown web of capillaries that pass through the bones of mice. Textbooks describe large veins and arteries jutting out the ends of bones, but this newly-described network of tunnels provide a faster route for blood cells produced in the bone marrow to enter the circulation. The research team also looked at human bones using a variety of methods: taking photos from patients undergoing surgery, conducting MRI scans of a healthy leg, and investigating extracted samples under a microscopeand revealed a similar, albeit less extensive, system of capillaries.

Last October, researchers reported that muscles typically seen in reptiles and other animalsbut not peoplewere present in the limbs of human embryos. Using a combination of immunostaining, tissue clearing, and microscopy, the team generated high-resolution 3-D images of upper and lower limb muscles in tissue samples from preserved 8- to 14-week-old embryos and fetuses. These structures, which disappear before birth, may be anatomical remnants of our evolutionary ancestors that disappear during the early stages of development, the authors suggest. They only examined 13 images, however, so experts caution that its a preliminary finding that needs to be replicated in a larger sample.

The fabella, a tiny bone located in a tendon behind the knee, is becoming more common in humans, according to a study published last spring. After reviewing 58 studies on fabella prevalence in 27 different countries, researchers reported that people were approximately 3.5 times more likely to have the little bone in 2018 than 1918. The cause of this trend remains an open question, but the authors suggest that changes in muscle mass and bone lengthdriven by increased diet quality in many parts of the worldcould be one explanation.

Diana Kwon is a Berlin-based freelance journalist. Follow her on Twitter@DianaMKwon.

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Synthetic Biology Market to Witness a CAGR of 23.9% Through 2020-2025 – Increasing Demand for Protein Therapeutics & Personalized Medicine, Increasing…

§ February 19th, 2020 § Filed under Nano Medicine Comments Off on Synthetic Biology Market to Witness a CAGR of 23.9% Through 2020-2025 – Increasing Demand for Protein Therapeutics & Personalized Medicine, Increasing…

DUBLIN, Feb. 17, 2020 /PRNewswire/ -- The "Synthetic Biology Market by Tools (Oligonucleotides, Enzymes, Synthetic Cells), by Technology (Gene Synthesis, Bioinformatics), by Application (Tissue Regeneration, Biofuel, Renewable Energy, Food & Agriculture, Bioremediation) - Global Forecast to 2025" report has been added to ResearchAndMarkets.com's offering.

The global synthetic biology market is projected to reach USD 19.8 billion by 2025 from USD 6.8 billion in 2020, at a CAGR of 23.9%.

This report analyzes the market for various synthetic biology market and their adoption patterns. It aims at estimating the market size and future growth potential of the synthetic biology market and its subsegments. The report also includes an in-depth competitive analysis of the key players in this market, along with their company profiles, product offerings, and recent developments.

Factors such as the increasing demand for synthetic genes and synthetic cells, wide range of applications of synthetic biology, declining cost of DNA sequencing and synthesizing, increasing R&D funding and initiatives in synthetic biology, and increasing investments in the market are propelling the growth of this market. However, rising biosafety, biosecurity, and ethical concerns related to synthetic biology are likely to hamper the growth of this market.

The oligonucleotides and synthetic DNA segment is expected to grow at the highest rate during the forecast period

Based on tools, the market has been segmented into oligonucleotides and synthetic DNA, enzymes, cloning technology kits, chassis organisms, xeno-nucleic acids, and synthetic cells. In 2019, the oligonucleotides and synthetic DNA segment is expected to register the highest CAGR during the forecast period.

This can be attributed to factors such as the rising demand for synthetic DNA, synthetic RNA, and synthetic genes, which are used in a wide range of applications, such as pharmaceuticals, nutraceuticals, personal care, flavors and fragrances, probiotics, green chemicals, and industrial enzymes.

The genome engineering segment is expected to grow at the highest CAGR during the forecast period

On the basis of technology, the market is segmented into gene synthesis, genome engineering, cloning, sequencing, site-directed mutagenesis, measurement and modeling, microfluidics, nanotechnology, bioinformatics technologies.

The genome engineering segment is expected to register the highest CAGR during the forecast period due to factors such as the increasing use of engineering technologies for manipulating complex genomes, growing therapeutics development for cancer and other diseases, and the increasing technological advances in CRISPR-toolbox and DNA synthesis technologies.

The industrial applications segment is expected to grow at the highest CAGR during the forecast period

Based on application, the synthetic biology market is segmented into medical, industrial, food & agricultural, and environmental applications. The industrial applications segment is expected to grow at the highest CAGR owing to the rising applications of synthetic biology in producing renewable energy, biomaterials & green chemicals, and enzymes.

The Asia Pacific is projected to witness the highest growth during the forecast period

The synthetic biology market is divided into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. In 2019, North America accounted for the largest share of the synthetic biology market.

However, the APAC region is expected to witness the highest growth during the forecast period owing to the growth in the number of pharmaceutical & biopharmaceutical companies, the increasing number of healthcare & life science facilities, and increasing requirements for regulatory compliance in pharmaceutical and biopharmaceutical companies, growing number of international alliances, heavy funding for synthetic biology research, and strong government support.

Furthermore, the increasing focus on the Asia Pacific markets due to their low-cost manufacturing advantage also provides growth opportunities for manufacturers.

Key Topics Covered

1 Introduction

2 Research Methodology

3 Executive Summary

4 Premium Insights 4.1 Market Overview4.2 Asia Pacific: Market, By Application4.3 Market: Geographic Growth Opportunities4.4 Market, By Region (2018-2025)4.5 Market: Developed vs. Developing Markets

5 Market Overview 5.1 Introduction5.2 Market Dynamics5.2.1 Drivers5.2.1.1 Wide Range of Applications of Synthetic Biology5.2.1.2 Rising R&D Funding and Growing Initiatives in Synthetic Biology5.2.1.3 Declining Cost of DNA Sequencing and Synthesizing5.2.1.4 Increasing Investments in the Market5.2.2 Restraints5.2.2.1 Biosafety, Biosecurity, and Ethical Concerns5.2.3 Opportunities5.2.3.1 Rising Need for Fuel Alternatives5.2.3.2 Increasing Demand for Protein Therapeutics and Personalized Medicine5.2.3.3 Increasing Research in Synthetic Drugs and Vaccines5.2.4 Challenges5.2.4.1 Standardization of Biological Parts

6 Synthetic Biology Market, By Tool 6.1 Introduction6.2 Oligonucleotides & Synthetic DNA6.2.1 Oligonucleotides and Synthetic Dna to Dominate the Market During the Forecast Period6.3 Enzymes6.3.1 Development of Enzymes has Helped in Evolving New Therapies for A Range of Diseases6.4 Cloning Technology Kits6.4.1 Need for the Creation of Artificial Dna Along With Their Assembly is Driving the Growth of the Segment6.5 Synthetic Cells6.5.1 Synthetic Cells Will Allow Tailoring Biologics and Its Adoption is Expected to Grow in the Coming Years6.6 Chassis Organisms6.6.1 Increasing Demand for Fossil Fuels is Likely to Propel the Demand for Chassis Organisms6.7 Xeno-Nucleic Acids6.7.1 Xnas are Increasingly Researched With the Growing Demand for Breakthrough Medicine

7 Synthetic Biology Market, By Technology 7.1 Introduction7.2 Gene Synthesis7.2.1 Gene Synthesis to Dominate the Market During the Forecast Period7.3 Genome Engineering7.3.1 Increasing Demand for Synthetic Dna and Genes is Expected to Drive Market Growth7.4 Sequencing7.4.1 Ngs Technology is Rapidly Becoming an Indispensable and Universal Tool for Biological Research7.5 Bioinformatics7.5.1 Use of Bioinformatics Technologies is Increasing With the Rising Need for Data Management and Curation7.6 Cloning7.6.1 Cloning Aids in Building New Genetic Modules/Pathways, Enabling Rapid Advances in Research Across Various Industries7.7 Site-Directed Mutagenesis7.7.1 Wide Applications in Genetic Engineering, Dna Assembly, and Cloning Technologies is Driving This Segment7.8 Measurement & Modeling7.8.1 Computational Modeling is Aiding the Growth of the Segment During the Forecast Period7.9 Microfluidics7.9.1 Droplet Microfluidics is Gaining Wide Recognition in the Field of Synthetic Biology7.1 Nanotechnology7.10.1 Convergence Between Synthetic Biology and Nanotechnologies Aid in Building Complex Bodies

8 Synthetic Biology Market, By Application 8.1 Introduction8.2 Medical Applications8.2.1 Pharmaceuticals8.2.1.1 In 2019, the Pharmaceuticals Segment Accounted for the Largest Share of the Medical Applications Market8.2.2 Drug Discovery and Therapeutics8.2.2.1 Cancer Detection & Diagnostics8.2.2.1.1 With Rising Investments for Cancer Research, the Market for Synthetic Biology is Expected to Grow for This Segment8.2.2.2 Other Drug Discovery and Therapeutic Applications8.2.3 Artificial Tissue & Tissue Regeneration8.2.3.1 Bio-Synthesis8.2.3.1.1 Bio-Synthesis is Dominating the Market With Its Increasing Adoption in Creating Artificial Genomes8.2.3.2 Stem Cell Regulation8.2.3.2.1 Use of Synthetic Biology in Stem Cell Regeneration and Reprogramming Somatic Cells is Expected to Drive Market Growth8.2.3.3 Other Artificial Tissue and Tissue Regeneration Applications8.3 Industrial Applications8.3.1 Biofuel and Renewable Energy8.3.1.1 Advantages of Using Genetically Engineered Organisms for the Synthetic Production of Biofuels is Driving Market Growth8.3.2 Industrial Enzymes8.3.2.1 Textile Industry8.3.2.1.1 Synthetic Biology is Being Applied in the Textile Industry to Replace Traditional Raw Materials8.3.2.2 Paper Industry8.3.2.2.1 Enzymes are Being Increasingly Used in the Pulp and Paper Industry8.3.2.3 Other Industries8.3.3 Biomaterials & Green Chemicals8.3.3.1 Silk-Based Proteins are A Type of Biomaterial Prepared Through Synthetic Biology8.4 Food & Agriculture8.4.1 Synthetic Biology Techniques are Applied in the Food and Agriculture Industry to Produce Metabolites, Health Products, and Processing Aids8.5 Environmental Applications8.5.1 Bioremediation8.5.1.1 Owing to the Growing Severity of Environmental Problems, It has Become Necessary to Develop Cost-Effective, On-Site Methods for Environmental Monitoring and Bioremediation8.5.2 Biosensing8.5.2.1 Biosensor Applications Commonly Make Use of Microalgae Owing to Their High Reproductive Rates and Ease of Culturing Due to Their Microscopic Size

9 Synthetic Biology Market, By Region 9.1 Introduction9.2 North America9.2.1 US9.2.1.1 The US Dominates the North American Market9.2.2 Canada9.2.2.1 Strong Research Infrastructure and Availability of Funding Will Support Market Growth9.3 Europe9.3.1 UK9.3.1.1 The UK Holds the Largest Share of the European Market9.3.2 Germany9.3.2.1 The Rapidly Growing Pharmaceutical Market is Expected to Drive Market Growth9.3.3 France9.3.3.1 Research Across All Industries is Strongly Supported By the Government9.3.4 Denmark9.3.4.1 Denmark has the Third-Largest Commercial Drug-Development Pipeline in Europe9.3.5 Switzerland9.3.5.1 Market Growth is Primarily Driven By the Well-Established Pharmaceutical & Biotechnology Industry in the Country9.3.6 Spain9.3.6.1 Spain has A Well-Established Network of Research Centers, Universities, and Hospitals, Which Form an Ideal Environment for Research9.3.7 Italy9.3.7.1 Growth in This Market is Mainly Driven By Increasing Life Science R&D in the Country, Funded By Both Public and Private Organizations9.3.8 Rest of Europe9.4 Asia Pacific9.4.1 Japan9.4.1.1 Large Number of Research Initiatives Towards the Development of Precision Medicine Supporting Market Growth9.4.2 China9.4.2.1 Growth in R&D to Enhance the Technological Capabilities in the Country, Thereby Driving the Demand for High-Quality Research Tools9.4.3 Australia9.4.3.1 Increasing Focus of the Healthcare System on Precision Medicine to Offer Significant Growth Opportunities9.4.4 India9.4.4.1 Increasing Pharma R&D and Government Funding in the Biotechnology Industry are the Major Factors Driving Market Growth9.4.5 Rest of Asia Pacific9.5 Latin America9.5.1 Strong Pharmaceutical Industry in the Region to Provide Significant Growth Opportunities9.6 Middle East and Africa9.6.1 Increasing Partnerships Among Global Players With Government Organizations in the Region to Support Growth

10 Competitive Landscape 10.1 Overview10.2 Market Share Analysis10.2.1 Synthetic Biology Market, By Key Players, 201810.3 Competitive Leadership Mapping10.3.1 Visionary Leaders10.3.2 Innovators10.3.3 Dynamic Differentiators10.3.4 Emerging Companies10.4 Competitive Situation and Trends10.4.1 Product Launches10.4.2 Expansions10.4.3 Acquisitions10.4.4 Other Strategies

11 Company Profiles 11.1 Thermo Fisher Scientific Inc.11.1.1 Business Overview11.1.2 Products Offered11.1.3 Recent Developments11.2 Merck KGaA11.3 Agilent Technologies Inc.11.4 Novozymes A/S11.5 Ginkgo Bioworks11.6 Amyris Inc.11.7 Intrexon Corporation11.8 Genscript Biotech Corporation11.9 Twist Bioscience11.10 Synthetic Genomics Inc. (SGI)11.11 Codexis Inc.11.12 Synthego Corporation11.13 Creative Enzymes11.14 Eurofins Scientific11.15 Cyrus Biotechnology Inc.11.16 Other Major Companies11.16.1 Atum11.16.2 Teselagen11.16.3 Arzeda11.16.4 Integrated DNA Technologies Inc.11.16.5 New England Biolabs

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RICK MacLEAN: We need a nudge to sign donor cards – SaltWire Network

§ February 19th, 2020 § Filed under Nano Medicine Comments Off on RICK MacLEAN: We need a nudge to sign donor cards – SaltWire Network

Rick MacLean

Someday, perhaps quite soon, a piece of Trina Doyles liver will begin living inside someone elses body.

A single mother of two living in Tignish, shes due to head to Toronto General Hospital soon so she can donate a piece of her liver - to a stranger.Its not a simple process.

But it could be, says Daniel Ariely. Hes an expert in how we make up our minds about everything from what we eat for breakfast in the morning to, well, going under the knife to help ease the always chronic lack of organs needed for donation.

Trina first.

She began pondering the idea of helping others as a teen when someone in her community needed a bone marrow transplant.

That didnt work out. She wasnt a match.

See, this isnt easy.

She became a blood donor, then signed up to give up some of her stem cells, microscopic bits of us that have the nearly magical ability to become anything from muscle to brain cells. They can also help repair damage, making them a hot item in medicine today.

Organ donation is much more complicated. There are concerns about the donors physical health, mental health, even financial health. Getting the nod can take time.

But the liver is a special case when it comes to donation. Cut out a piece and put it into someone else and it grows a whole new liver. Meanwhile, the donors liver grows right back.

Noticing a Facebook posting about organ donation was the final nudge Trina needed to take the plunge. Around Christmas, 2018, she signed up for the organ donation registry.

And "nudge"brings us to Ariely.

Hes a professor of psychology and something called behavioural economics at Duke University in the U.S.

He believes he knows how you make up your mind better than you do. Far better.

Consider organ donation, he says. Your chances of finding a donor in Europe depend on where you live.

If you call Denmark home. Just 4.25 per cent of drivers there have signed an organ consent form. But if youre in France, the number leaps to 99.91 per cent. Germany? Just 12 per cent.

But Hungary? How does 99.997 sound?

Now, Europe is not a big place. Hop in a car in Paris and you can arrive in Bonn, Germany about 500 kilometres and six hours later.

So what gives, when it comes to signing an organ donor card? Why the huge differences?

Were lazy, Ariely says. A simple nudge can influence us.

Countries with the best numbers use an opt-out plan, he says. They assume you want to be a donor - unless you fill out a form saying otherwise. Most people cant be bothered.

Most of Canada assumes you dont want to be donor. You must fill out a form to say you want to help. Most people cant be bothered.

Nova Scotia is an exception. It has passed a law, the first in North America, that assumes you want to donate. It is expected to take effect this year.

Here, Charlottetown-West Royalty MLA Gord McNeilly asked the province last fall to consider doing the same thing. The government is considering the idea.Good plan.

It would mean those in need would have to depend less on people like Doyle, remarkable as her kindness is, and more on the rest of us.

Rick MacLean is an instructor in the journalism program at Holland College in Charlottetown.

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Enriching newborns’ environment in the right way helps heal young, injured brains – PRNewswire

§ February 19th, 2020 § Filed under Nano Medicine Comments Off on Enriching newborns’ environment in the right way helps heal young, injured brains – PRNewswire

WASHINGTON, Feb. 19, 2020 /PRNewswire/ -- An enriched environmentwith increased opportunities for physical activity, socialization and exploring novel stimulihelped lessen functional, anatomical and cellular deficits in an experimental model of brain damage caused by oxygen deprivation at birth. What's more, recovery of the brain's white matter required a combination of all experimental interventions, not just a single intervention, suggests a new study led by researchers at Children's National Hospital. Their findings, published online Feb. 19, 2020, in "Nature Communications," could lead to new treatments for children affected by this condition.

About 450,000 babies are born preterm in U.S. every year, a number that continues to rise, says senior author Vittorio Gallo, Ph.D., chief research officer for Children's National Hospital and scientific director for Children's National Research Institute. Oxygen deprivation caused by immature lungs or birth injuries is a common consequence of prematurity, which leads to permanent neurological deficits and disabilities, Gallo explains.

Premature babies require minimal handling for their first months of life in order to eliminate stressful stimuli and optimize their development. Efforts have been made to switch from the noisy and crowded environment of the older neonatal intensive care units to new, quiet private family rooms in order to eliminate noise and light. However, recent studies suggest that infants that were treated in private family rooms had lower language and motor scores compared to the infants in open wards, raising questions about the ideal level of stimulation that premature neonates require in order to achieve optimal brain development. The mechanisms by which environmental stimuli positively affect brain development in the early neonatal period and better neurological outcomes remain unclear.

To determine how enriched environments may affect recovery for newborns who suffer brain injury after birth, Gallo and colleagues leveraged a preclinical model of newborns exposed to low oxygen levels shortly after birth. These experimental models had brain damage similar to premature human babies with hypoxic brain injuries.

After injury, some of these experimental models grew up in standard enclosures, with little more than nesting materials, a few other cage mates, and access to food and water. Others grew up in enriched environments: larger enclosures equipped with a running wheel as well as objects of differing sizes and colors that were switched out frequently, and more cage mates for enhanced socialization.

When these preclinical models were young adults, the researchers assessed how well they performed on a functional test of motor skills in which both groups scurried up a narrow, inclined beam. While foot slips were common in both groups, those raised in an enriched environment had about half as many as those raised in the less-stimulating enclosures.

When researchers examined the brains, they found that these functional improvements were linked to significantly enhanced division and maturation of oligodendrocytes, cells in the brain's white matter that support nerve cells and produce myelin, a fatty insulating sheath that covers the long extensions that connect nerve cells to each other and to other parts of the body. Indeed, consistent with the cellular and functional findings, the white matter of experimental models raised in enriched environments had significantly more myelin content than that of counterparts raised in the simpler environment.

Further experiments showed that for these improvements in function and anatomy to occur in experimental models raised in the enriched environments, they needed all three elements: enhanced physical activity, socialization and cognitive stimulation from novel objects. Additionally, exposure to these elements needed to start early and be continuous and long term. Those experimental models that weren't raised in a completely enriched environment or whose exposure to the environment started later, was interrupted, or was cut short didn't have any improvements in function and white matter recovery.

Digging deeper, Gallo and colleagues employed next generation sequencing to investigate oligodendrocyte gene expression in these animals, identifying broad differences in networks of genes involved in oligodendrocyte development between the two groups.

Gallo notes that these results and future studies to better understand the effects of enriched environments could lead to better ways to care for premature babies that help lessen or prevent the long-term consequences of oxygen deprivation.

In addition to Gallo, other Children's National co-authors include Thomas A. Forbes, Ph.D., co-lead author, Evan Z. Goldstein, Ph.D., and co-authors Beata Jablonska, Ph.D., Joseph Scafidi, D.O., Katrina L. Adams, Ph.D. and Kazue Hashimoto-Torii, Ph.D.; additional authors include Jeffrey L. Dupree, Ph.D., Virginia Commonwealth University; and Yuka Imamura, Ph.D., Penn State University.

Financial support for research described in this post was provided by the District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) under award No. U54HD090257, the National Institutes of Health (NIH) under award Nos. R37NS109478, F31NS100277, F32NS106723 and 5R01NS099461. Microscopic analyses were carried out at the Children's National Research Institute Cell and Tissue Microscopy Core, which is supported by DC-IDDRC. The study authors also acknowledge the support of the CRI Bioinformatics Unit, a partnership between the Children's Research Institute, the Center for Genetic Medicine Research, the Clinical Translational Science Institute at Children's National (CTSI-CN) and the DC-IDDRC. The CTSI-CN is supported by the NIH under grant Nos. UL1TR001876 and KL2TR001877.

Summary: Preclinical model of oxygen deprivation, a common consequence of prematurity, showed better recovery when exposed to a combination of increased physical activity, socialization and cognitive stimulation

About Children's National HospitalChildren's National Hospital, based in Washington, D.C., celebrates150yearsof pediatric care, research and commitment to community. Volunteers opened the hospital in 1870 with 12 beds to care for Civil War orphans. Today, 150 years stronger, it is the nation's No. 6 children's hospital. It is ranked No. 1 fornewborn carefor the third straight year and ranked in all specialties evaluated by "U.S. News & World Report." Children's National is transforming pediatric medicine for all children. In 2020, it will open the Children's National Research & Innovation Campus, the first in the nation dedicated to pediatric research. It has been designated twice as a Magnethospital, demonstrating the highest standards of nursing and patient care delivery. This pediatric academic health system offers expert care through a convenient, community-based primary care network and specialty outpatient centers in the D.C., metropolitan area, including the Maryland and Northern Virginia suburbs. Children's National is home to theChildren's National Research InstituteandSheikh Zayed Institute for Pediatric Surgical Innovationand is the nation's seventh-highest NIH-funded children's hospital. It is recognized for its expertise and innovation in pediatric care and as a strong voice for children through advocacy at the local, regional and national levels.

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How Nanomedicine is Going Green and Fighting Superbugs – CareDash News

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on How Nanomedicine is Going Green and Fighting Superbugs – CareDash News

Nanomaterials are materials with one dimension less than 100 nanometers. A nanometer is one-billionth of a meter. Professor Thomas Webster directs the Nanomedicine Laboratory at Northeastern University. His lab designs, synthesizes, and evaluates nanomaterials for various medical implant applications. CareDash CEO and Managing Editor Ted Chan interviewed Dr. Webster about nanotech innovation.

We focus on the synthesis, design, and evaluation of nanomaterials (that is, tubes, particles, etc. with dimensions usually less than 100 nm) in medicine. Specifically, we were the first group to demonstrate increased tissue growth (such as bone, cartilage, vascular, bladder, nervous system, etc.) on nanomaterials compared to conventional implants. We were also the first group to report decreased infection on nanomaterials compared to conventional implants, even without the use of drugs. We have also been pioneering the use of implantable nanosensors to detect disease, communicate such information to a handheld device, and kill the disease on-demand.

As just one example, we have a growing alarming number of antibiotic-resistant infections that are crippling our healthcare system. In fact, the U.S. Centers for Disease Control has predicted that more people will die from antibiotic-resistant infections than all cancers combined by 2050. We created this problem, and we can solve it. So, in simple terms, we are killing bacteria using nanoparticles, but not antibiotics. We can even kill antibiotic-resistant bacteria with nanoparticles, whereas antibiotics fail. Decreasing infection from any bacteria, especially antibiotic-resistant bacteria, will significantly increase health.

In addition to those medical advances mentioned above (implantable sensors, nanoparticles that can kill antibiotic-resistant bacteria, nanomaterials to increase tissue growth, etc.), I am particularly excited about green nanomedicine.

Green nanomedicine is where we can use natural materials to create medical devices and nanoparticles. This is important since a significant portion of the "plastic island" in the Pacific Ocean is composed of plastics from the medical community, yet very few people are studying green biomaterials or green nanomedicine. We are here at Northeastern Nanomedicine Laboratory. We have been creating green medical devices and green nanoparticles, which is saving our environment and are more effective in their function than the respective conventional materials.

Persistence. We have started over 13 companies with over 23 FDA approved implants. Research is hard enough, but getting the funding to commercialize your products is even harder. I have learned throughout my career in so many ways never to give up, and if you believe in technology, persist until it is saving human lives.

Dr. Webster is a Keynote Speaker at the 2ndBiomedical Engineering and Instrumentation Summit(BEIS 2020), a conference organized to promote awareness and enhance research in biomedical engineering. BEIS 2020 will be held on July 20-22, 2020, in Boston, MA.

Disclosure: CareDash is a media partner of the BEIS Summit at which Dr. Webster is a keynote speaker in 2020. Dr. Webster and CareDash have no financial affiliation.

You can also tweet us questions and comments@caredash.

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Rapid Industrialization in Emerging Countries to Bolster the Growth of the Healthcare Nanotechnology (Nanomedicine) Market during 2015 2021 – Redhill…

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on Rapid Industrialization in Emerging Countries to Bolster the Growth of the Healthcare Nanotechnology (Nanomedicine) Market during 2015 2021 – Redhill…

The comprehensive report published by Persistence Market Research offers an in-depth intelligence related to the various factors that are likely to impact the demand, revenue generation, and sales of the Healthcare Nanotechnology (Nanomedicine) Market. In addition, the report singles out the different parameters that are expected to influence the overall dynamics of the Healthcare Nanotechnology (Nanomedicine) Market during the forecast period 2015 2021.

As per the findings of the presented study, the Healthcare Nanotechnology (Nanomedicine) Market is poised to surpass the value of ~US$ XX by the end of 2029 growing at a CAGR of ~XX% over the assessment period. The report includes a thorough analysis of the upstream raw materials, supply-demand ratio of the Healthcare Nanotechnology (Nanomedicine) in different regions, import-export trends and more to provide readers a fair understanding of the global market scenario.

ThisPress Release will help you to understand the Volume, growth with Impacting Trends. Click HERE To get SAMPLE PDF (Including Full TOC, Table & Figures) athttps://www.persistencemarketresearch.co/samples/6370

The report segregates the Healthcare Nanotechnology (Nanomedicine) Market into different segments to provide a detailed understanding of the various aspects of the market. The competitive analysis of the Healthcare Nanotechnology (Nanomedicine) Market includes valuable insights based on which, market players can formulate impactful growth strategies to enhance their presence in the Healthcare Nanotechnology (Nanomedicine) Market.

Key findings of the report:

The report aims to eliminate the following doubts related to the Healthcare Nanotechnology (Nanomedicine) Market:

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Key players in the global nanomedicine market include: Abbott Laboratories, CombiMatrix Corporation, GE Healthcare, Sigma-Tau Pharmaceuticals, Inc., Johnson & Johnson, Mallinckrodt plc, Merck & Company, Inc., Nanosphere, Inc., Pfizer, Inc., Celgene Corporation, Teva Pharmaceutical Industries Ltd., and UCB (Union chimique belge) S.A.

Key geographies evaluated in this report are:

Key features of this report

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Nanomedicine Market by Key Manufacturers, Regions, Risk Analysis, Industry Share, Driving Factors, Deployment Policy, Innovative Technology, Product…

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on Nanomedicine Market by Key Manufacturers, Regions, Risk Analysis, Industry Share, Driving Factors, Deployment Policy, Innovative Technology, Product…

Global Nanomedicine Market report provides you with detailed insights, industry knowledge, market forecasts and analytics. The report on the global Nanomedicine industry also clarifies economic risks and environmental compliance. Global Nanomedicine market report assists industry enthusiasts including investors and decision makers to make confident capital investments, develop strategies, optimize their business portfolio, innovate successfully and perform safely and sustainably.

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Key Companies

The report offers detailed coverage of Nanomedicine industry and main market trends. The market research includes historical and forecast market data, demand, application details, price trends, and company shares of the leading Nanomedicine by geography. The report splits the market size, by volume and value, on the basis of application type and geography.

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Key Product Type

Market by Application

Nanomedicine Market Segment by Regions

Asia-Pacific: China, Southeast Asia, India, Japan, Korea, Oceania

Europe: Germany, UK, France, Italy, Russia, Spain, Netherlands, Turkey, Switzerland

North America: United States, Canada, Mexico

Middle East & Africa: GCC, North Africa, South Africa

South America: Brazil, Argentina, Columbia, Chile, Peru

The key points of the Nanomedicine Market report:

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Global Nanomedicine Market providing information such as company profiles, product picture, and specification, capacity, production, price, cost, revenue and contact information. Upstream raw materials and equipment and downstream demand analysis are also carried out. The Global Nanomedicine market development trends and marketing channels are analysed. Finally, the feasibility of new investment projects is assessed and overall research conclusions offered.

Key Points from Table of Content

1 Nanomedicine Industrial Chain Overview2 Global Nanomedicine Market Production & Consumption by Geography3 Nanomedicine Market Major Manufacturers Introduction4 Nanomedicine Market Competition Pattern5 Nanomedicine Product Type Segment6 Nanomedicine End-Use Segment7 Nanomedicine Market Forecast & Trend8 Nanomedicine Price & Channel9 Nanomedicine Market Drivers & Investment Environment10 Research Conclusion

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Turkish doctor creates first see-through 3D maps of human kidney and eye – Daily Sabah

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on Turkish doctor creates first see-through 3D maps of human kidney and eye – Daily Sabah

A Turkish doctor and his 15-member team have managed to render transparent 3D models of the human eye and kidney in what the scientific community heralds as an important development in organ production, the fight against cancer and even the mapping of the brain.

Genetics and neuroscience specialist Dr. Ali Ertrk, the director of the Institute for Tissue Engineering and Regenerative Medicine at Helmholtz Zentrum Mnchen and also principal investigator at the Institute for Stroke and Dementia Research at Ludwig Maximilian University's hospital, talked about their pioneering project in which they used microscopic imaging technology to reveal underlying complex structures of human organs by making them see-through. Their findings were published in the scientific journal Cell on Feb. 13.As part of the final stage of their project, Ertrk said they developed a new technology called SHANEL (Small-micelle-mediated HumAN organ Efficient clearing and Labeling) which is essentially a 3D laser microscope that can scan large tissues. Up until now, scientists had only managed to obtain cellular views of intact mouse organs in 3D. The chemicals used to turn mouse organs see-through did not work on human parts because of the accumulation of insoluble molecules including collagen over many years. After many trials, the team discovered CHAPS, a detergent that could seep into thick human organs and turn them transparent.

"We started these studies three years ago. In order to make 3D maps of these organs at a cellular level, we first had to make them visible under a laser microscope. Last year, we succeeded in making organs donated from cadavers transparent with various chemical solutions, as if turning milk into water," Demirren News Agency (DHA) quoted Ertrk as saying."We also developed an artificial intelligence algorithm that reduces the analysis of millions of images that we have obtained from the microscope, which would normally take humans centuries to analyze, down to just a few hours. Thus, for the first time in the world, we were able to make a 3D map of the human kidney and eye at the cellular level," he added.

The method could become a key technology for mapping intact human organs in the near future and hence "dramatically accelerate our understanding of organs such as the brain, their development and function in health and disease," explained Ertrk.

He said they believe that Shanel can help map the human brain at a molecular level and produce artificial human organs at a cellular level thanks to the 3D-bioprinting technology. Ertrk said they are currently working on mapping major organs such as the heart, kidney and pancreas.

"There is a huge shortage of organ donors for hundreds of thousands of people. The waiting time for patients and the transplantation costs are a real burden. Detailed knowledge about the cellular structure of human organs brings us an important step closer to creating functional organs artificially on demand," the biotech specialist said in a press release.

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On Nature column: A short history of limestone – The Herald Bulletin

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on On Nature column: A short history of limestone – The Herald Bulletin

Glacial deposits of sand and gravel have been waiting for 11,500 years to be discovered, mined and used to make modern life possible.

We depend on limestone quarries for a mind-boggling array of uses and end products that include agricultural lime, paper, fillers, asphalt, concrete, Portland cement, bridges, roads, building materials, monuments, medicine, makeup, toothpaste, paint, household cleaners, landscaping stone, nutritional supplements and animal feed. Many famous buildings like the Empire State Building, the Biltmore mansion, the Pentagon, Yankee Stadium, the National Cathedral and 35 state capitols were built from Indiana limestone.

After a quarry has been mined and groundwater fills it in, it can be transformed into a municipal water supply, a recreational resource or wildlife habitat. The series of gravel pits in northern Madison County along Killbuck and Little Killbuck creeks are prime examples of gravel pits that were mined out and converted to recreational and other uses.

The story of Indiana limestone began underneath a vast inland sea that covered much of North America more than 400 million years ago. At that time (the Silurian Period), the sea was filled with now extinct microscopic shelled organisms, giant scorpions, crinoids, coral, trilobites and armored fish. These life forms were able to extract calcium carbonate from the water and transform it into the calcium carbonate of their shells. As they died and sank to the ocean floor, they were covered by layer after layer of the remains of other organisms and sediment and cemented together under pressure to become limestone. Limestone is quite soft, varies in color from white to gray, and is at least 50% calcite or dolomite.

After a time, forces deep within the Earths crust lifted what was once the ocean floor hundreds of feet above sea level, becoming outcroppings of sedimentary rock like limestone, sandstone and shale. The road cut south of Wabash is an excellent example of shale formed from mud at the bottom of an ancient sea.

Shifts in the Earths crust and changes in the amount of carbon dioxide in the atmosphere are continually affecting the Earths climate. Beginning about 2.4 million years ago, a series of ice sheets advanced and retreated over present-day North America. The most recent ice age (the Wisconsin glaciation) ended about 11,500 years ago. At that time, huge sheets of ice covered the northern two-thirds of Indiana. Glaciers pretty well pulverized most limestone outcroppings and much of the land surface, leaving this part of the state relatively flat. As the climate warmed and glaciers began to retreat, melt water formed depressions filled with rushing water that carried silt, sand and gravel along with it. The heaviest particles settled out first followed by progressively lighter particles, eventually producing layers of sedimentary rock (strata).

In east-central Indiana, we have an abundance of aggregate (sand and gravel) quarries currently in operation. Salem limestone is mined near Bloomington and Bedford and was immortalized in the film Breaking Away.

Sheryl Myers taught biology and environmental science for 34 years and has worked as a naturalist for area parks. She is a founding director of Heart of the River Coalition. On Nature is published Tuesdays in The Herald Bulletin.

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A Rare Human Disease Has Been Found in Dinosaur Bones, Could it Lead to a Treatment? – PharmaLive

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on A Rare Human Disease Has Been Found in Dinosaur Bones, Could it Lead to a Treatment? – PharmaLive

It is largely accepted that the dinosaurs were killed off due to an asteroid impact on the planets surface that created a chain reaction of climactic calamities at least, thats the primary theory. And while all that is left of dinosaurs are their bones, those fossilized pieces can still provide us with important scientific resources, including perhaps a key to at least one rare disease.

Researchers have discovered the remains of a dinosaur from what is now modern Alberta, Canada that contains evidence of having suffered a condition similar to a rare cancer of the bone marrow. In bone remains from a hadrosaur, a duck-billed dinosaur, researchers found lesions in tail vertebrae bones that are similar to the rare disease Langerhans cell histiocytosis (LCH), a type of cancer that begins in the bone marrow. Details of the study were published in Nature.

According to the Cleveland Clinic, LCH, previously known as histiocytosis X, is characterized by abnormal increases in white blood cells called histiocytes. The histiocyte cells help the bodys immune system fight infection and destroy foreign materials. The extra immune cells produced by this condition may form tumors, which can affect parts of the body like the bones and possibly spread to other areas, the clinic said on its website. It typically affects children between the ages of five and 10 years. There are less than 200,000 diagnoses annually. The most common form of LCH is eosinophilic granuloma. Most patients afflicted with LCH tend to recover, but the condition can cause pain and swelling.

Langerhans cell histiocytosis historically was thought of as a cancer-like condition, but more recently researchers have begun to consider it an autoimmune phenomenon in which immune cells begin to overproduce and attack the body instead of fighting infection. In most cases it is not known why the disorder appears, although there may be a genetic link, the Cleveland Clinic said on its website.

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Because of the different ways in which LCH can affect the body, there are different treatment options for people diagnosed with the disorder. In addition to steroid treatments, surgery and anti-inflammatory treatments can be recommended. Radiation treatment and chemotherapy can be used in some patients, the Histiocytosis Association noted on its website.

After a detailed study of the lesions in the hadrosaurs bones, the researchers confirmed that the issue afflicting the dinosaur was LCH. The researchers confirmed the diagnosis through macroscopic and microscopic analyses of the hadrosaur vertebrae and then compared to human LCH, as well as other pathologies. The hadrosaur pathology findings were indistinguishable from those of humans with LCH, supporting that diagnosis, the researchers said in their study abstract. The disease has been found in other animals, but this was the first time it was seen in a creature that died out millions of years ago.

Knowing that the disease has been discovered in dinosaurs could help lead to breakthroughs in potential treatments for the disease. Israel Hershkovitz, a palaeopathologist from Tel Aviv University who assisted in the study, told Science Alert that the goal of these kinds of studies, looking at disease states in long-dead creatures, could lead to an understanding of the causes of LCH and other diseases.

Ultimately, the goal of such studies is to understand the real cause of these illnesses and what evolutionary mechanisms allowed them to develop and survive, Hershkovitz told the publication. Perhaps if we understand a diseases underlying mechanisms we can treat its causes more effectively, instead of focusing on the symptoms, as modern medicine tends to do.

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Radiation Shielding And Monitoring Market to Expand with Significant CAGR during 2024 – Kentucky Journal 24

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on Radiation Shielding And Monitoring Market to Expand with Significant CAGR during 2024 – Kentucky Journal 24

The global market for radiation safety and protection and shielding applications should grow from $58.8 billion in 2019 to $72.9 billion by 2024, with a compound annual growth rate (CAGR) of 4.4% for 2019-2024.

Report Scope:

This report has been prepared in a simple, easy-to-understand format. Numerous tables and figures are included to illustrate current and future market scenarios. The report includes a detailed study of global and regional markets for various products and equipment involved in radiation monitoring and shielding, as well as the various applications for these products and equipment in different fields and industries, with reasons given for variations in the growth of the industry in certain regions.

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Report Includes:

69 tables Detailed overview of the global markets for various products and equipment involved in radiation monitoring and shielding and the various applications for these products and equipment in different fields and industries Analyses of the global market trends with data from 2017 and 2018, estimates for 2019, and projections of compound annual growth rates (CAGRs) through 2024 Quantitative analysis of the global and regional markets for radiation shielding and monitoring products and equipment by various end user segments such as forms of ionizing radiation, methods of radiation detection, radiation protection equipment and their sub-types, and applications of radiation detection Information on various types of radiation shielding materials, including their properties, uses and the future market outlook Discussion of technological, regulatory, and economic trends that are affecting the market Patent review and new developments in radiation monitoring and shielding products and equipment industry Company profiles of major manufacturers of radiation shielding and monitoring equipment, including Ametek Inc., Rapiscan Systems, S.E. International Inc., Scionix Holland B.V., IBA Dosimetry GmbH, Smiths Detection Inc., and Thermo Fisher Scientific Inc.

Summary

The increased use of ionization radiation in industry and medicine presents a health hazard, as it can cause microscopic damage to living tissue, resulting in skin burns and radiation sickness at high exposures. The advances in computed tomography, as well as the high radiation doses delivered by interventional procedures, have raised serious safety and health concerns for both patients and medical staff, requiring the establishment of a radiation protection culture (RPC) in every radiology department. The term culture in RPC describes the combination of attitudes, beliefs, practices and rules among the professionals, staff and patients regarding radiation protection. The establishment of such a culturerequires continuing education of the staff and professionals, effective communication at all levels and implementation of quality assurance programs. This culture must be brought about from the highest level of leadership. The establishment of an RPC enables the reduction of the radiation dose, enhances radiation risk awareness, minimizes unsafe practices and improves the quality of a radiation protection program.

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The major factors affecting the growth of market for radiation monitoring and shielding devices can be summarized as growing security threats, increasing global prevalence of cancer, increasing safety awareness among people working in radiation-prone environments and growing safety concerns after recently nuclear disasters.

The market for radiation monitoring and shielding has been divided into two segments Radiation detection, measurement and monitoring equipment. Radiation shielding, safety and protection equipment.

The following summary table and figure illustrate the market for various radiation safety and protection and shielding applications, which have been divided into five segments Personal protection applications. Homeland security and military applications. Radiation shielding applications. Medical and laboratory applications. Industrial and nuclear power applications.

The total market for radiation safety and protection and shielding applications was worth more than REDACTED in 2017. This market is expected to reach nearly REDACTED by the end of 2024, with an expected compound annual growth rate (CAGR) of REDACTED.

The Summary Table shows that personal protection applications dominate the market, with REDACTED in 2017, increasing to nearly REDACTED in 2024, with a CAGR of REDACTED. The Homeland security and military applications segment was worth REDACTED in 2017, and it is expected to reach REDACTED by 2024, with a CAGR of REDA CTED.

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Synthetic Biology Market to Witness a CAGR of 23.9% Through 2020-2025 – Increasing Demand for Protein Therapeutics & Personalized Medicine,…

§ February 18th, 2020 § Filed under Nano Medicine Comments Off on Synthetic Biology Market to Witness a CAGR of 23.9% Through 2020-2025 – Increasing Demand for Protein Therapeutics & Personalized Medicine,…

DUBLIN, Feb. 17, 2020 /PRNewswire/ -- The "Synthetic Biology Market by Tools (Oligonucleotides, Enzymes, Synthetic Cells), by Technology (Gene Synthesis, Bioinformatics), by Application (Tissue Regeneration, Biofuel, Renewable Energy, Food & Agriculture, Bioremediation) - Global Forecast to 2025" report has been added to ResearchAndMarkets.com's offering.

The global synthetic biology market is projected to reach USD 19.8 billion by 2025 from USD 6.8 billion in 2020, at a CAGR of 23.9%.

This report analyzes the market for various synthetic biology market and their adoption patterns. It aims at estimating the market size and future growth potential of the synthetic biology market and its subsegments. The report also includes an in-depth competitive analysis of the key players in this market, along with their company profiles, product offerings, and recent developments.

Factors such as the increasing demand for synthetic genes and synthetic cells, wide range of applications of synthetic biology, declining cost of DNA sequencing and synthesizing, increasing R&D funding and initiatives in synthetic biology, and increasing investments in the market are propelling the growth of this market. However, rising biosafety, biosecurity, and ethical concerns related to synthetic biology are likely to hamper the growth of this market.

The oligonucleotides and synthetic DNA segment is expected to grow at the highest rate during the forecast period

Based on tools, the market has been segmented into oligonucleotides and synthetic DNA, enzymes, cloning technology kits, chassis organisms, xeno-nucleic acids, and synthetic cells. In 2019, the oligonucleotides and synthetic DNA segment is expected to register the highest CAGR during the forecast period.

This can be attributed to factors such as the rising demand for synthetic DNA, synthetic RNA, and synthetic genes, which are used in a wide range of applications, such as pharmaceuticals, nutraceuticals, personal care, flavors and fragrances, probiotics, green chemicals, and industrial enzymes.

The genome engineering segment is expected to grow at the highest CAGR during the forecast period

On the basis of technology, the market is segmented into gene synthesis, genome engineering, cloning, sequencing, site-directed mutagenesis, measurement and modeling, microfluidics, nanotechnology, bioinformatics technologies.

The genome engineering segment is expected to register the highest CAGR during the forecast period due to factors such as the increasing use of engineering technologies for manipulating complex genomes, growing therapeutics development for cancer and other diseases, and the increasing technological advances in CRISPR-toolbox and DNA synthesis technologies.

The industrial applications segment is expected to grow at the highest CAGR during the forecast period

Based on application, the synthetic biology market is segmented into medical, industrial, food & agricultural, and environmental applications. The industrial applications segment is expected to grow at the highest CAGR owing to the rising applications of synthetic biology in producing renewable energy, biomaterials & green chemicals, and enzymes.

The Asia Pacific is projected to witness the highest growth during the forecast period

The synthetic biology market is divided into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. In 2019, North America accounted for the largest share of the synthetic biology market.

However, the APAC region is expected to witness the highest growth during the forecast period owing to the growth in the number of pharmaceutical & biopharmaceutical companies, the increasing number of healthcare & life science facilities, and increasing requirements for regulatory compliance in pharmaceutical and biopharmaceutical companies, growing number of international alliances, heavy funding for synthetic biology research, and strong government support.

Furthermore, the increasing focus on the Asia Pacific markets due to their low-cost manufacturing advantage also provides growth opportunities for manufacturers.

Key Topics Covered

1 Introduction

2 Research Methodology

3 Executive Summary

4 Premium Insights 4.1 Market Overview4.2 Asia Pacific: Market, By Application4.3 Market: Geographic Growth Opportunities4.4 Market, By Region (2018-2025)4.5 Market: Developed vs. Developing Markets

5 Market Overview 5.1 Introduction5.2 Market Dynamics5.2.1 Drivers5.2.1.1 Wide Range of Applications of Synthetic Biology5.2.1.2 Rising R&D Funding and Growing Initiatives in Synthetic Biology5.2.1.3 Declining Cost of DNA Sequencing and Synthesizing5.2.1.4 Increasing Investments in the Market5.2.2 Restraints5.2.2.1 Biosafety, Biosecurity, and Ethical Concerns5.2.3 Opportunities5.2.3.1 Rising Need for Fuel Alternatives5.2.3.2 Increasing Demand for Protein Therapeutics and Personalized Medicine5.2.3.3 Increasing Research in Synthetic Drugs and Vaccines5.2.4 Challenges5.2.4.1 Standardization of Biological Parts

6 Synthetic Biology Market, By Tool 6.1 Introduction6.2 Oligonucleotides & Synthetic DNA6.2.1 Oligonucleotides and Synthetic Dna to Dominate the Market During the Forecast Period6.3 Enzymes6.3.1 Development of Enzymes has Helped in Evolving New Therapies for A Range of Diseases6.4 Cloning Technology Kits6.4.1 Need for the Creation of Artificial Dna Along With Their Assembly is Driving the Growth of the Segment6.5 Synthetic Cells6.5.1 Synthetic Cells Will Allow Tailoring Biologics and Its Adoption is Expected to Grow in the Coming Years6.6 Chassis Organisms6.6.1 Increasing Demand for Fossil Fuels is Likely to Propel the Demand for Chassis Organisms6.7 Xeno-Nucleic Acids6.7.1 Xnas are Increasingly Researched With the Growing Demand for Breakthrough Medicine

7 Synthetic Biology Market, By Technology 7.1 Introduction7.2 Gene Synthesis7.2.1 Gene Synthesis to Dominate the Market During the Forecast Period7.3 Genome Engineering7.3.1 Increasing Demand for Synthetic Dna and Genes is Expected to Drive Market Growth7.4 Sequencing7.4.1 Ngs Technology is Rapidly Becoming an Indispensable and Universal Tool for Biological Research7.5 Bioinformatics7.5.1 Use of Bioinformatics Technologies is Increasing With the Rising Need for Data Management and Curation7.6 Cloning7.6.1 Cloning Aids in Building New Genetic Modules/Pathways, Enabling Rapid Advances in Research Across Various Industries7.7 Site-Directed Mutagenesis7.7.1 Wide Applications in Genetic Engineering, Dna Assembly, and Cloning Technologies is Driving This Segment7.8 Measurement & Modeling7.8.1 Computational Modeling is Aiding the Growth of the Segment During the Forecast Period7.9 Microfluidics7.9.1 Droplet Microfluidics is Gaining Wide Recognition in the Field of Synthetic Biology7.1 Nanotechnology7.10.1 Convergence Between Synthetic Biology and Nanotechnologies Aid in Building Complex Bodies

8 Synthetic Biology Market, By Application 8.1 Introduction8.2 Medical Applications8.2.1 Pharmaceuticals8.2.1.1 In 2019, the Pharmaceuticals Segment Accounted for the Largest Share of the Medical Applications Market8.2.2 Drug Discovery and Therapeutics8.2.2.1 Cancer Detection & Diagnostics8.2.2.1.1 With Rising Investments for Cancer Research, the Market for Synthetic Biology is Expected to Grow for This Segment8.2.2.2 Other Drug Discovery and Therapeutic Applications8.2.3 Artificial Tissue & Tissue Regeneration8.2.3.1 Bio-Synthesis8.2.3.1.1 Bio-Synthesis is Dominating the Market With Its Increasing Adoption in Creating Artificial Genomes8.2.3.2 Stem Cell Regulation8.2.3.2.1 Use of Synthetic Biology in Stem Cell Regeneration and Reprogramming Somatic Cells is Expected to Drive Market Growth8.2.3.3 Other Artificial Tissue and Tissue Regeneration Applications8.3 Industrial Applications8.3.1 Biofuel and Renewable Energy8.3.1.1 Advantages of Using Genetically Engineered Organisms for the Synthetic Production of Biofuels is Driving Market Growth8.3.2 Industrial Enzymes8.3.2.1 Textile Industry8.3.2.1.1 Synthetic Biology is Being Applied in the Textile Industry to Replace Traditional Raw Materials8.3.2.2 Paper Industry8.3.2.2.1 Enzymes are Being Increasingly Used in the Pulp and Paper Industry8.3.2.3 Other Industries8.3.3 Biomaterials & Green Chemicals8.3.3.1 Silk-Based Proteins are A Type of Biomaterial Prepared Through Synthetic Biology8.4 Food & Agriculture8.4.1 Synthetic Biology Techniques are Applied in the Food and Agriculture Industry to Produce Metabolites, Health Products, and Processing Aids8.5 Environmental Applications8.5.1 Bioremediation8.5.1.1 Owing to the Growing Severity of Environmental Problems, It has Become Necessary to Develop Cost-Effective, On-Site Methods for Environmental Monitoring and Bioremediation8.5.2 Biosensing8.5.2.1 Biosensor Applications Commonly Make Use of Microalgae Owing to Their High Reproductive Rates and Ease of Culturing Due to Their Microscopic Size

9 Synthetic Biology Market, By Region 9.1 Introduction9.2 North America9.2.1 US9.2.1.1 The US Dominates the North American Market9.2.2 Canada9.2.2.1 Strong Research Infrastructure and Availability of Funding Will Support Market Growth9.3 Europe9.3.1 UK9.3.1.1 The UK Holds the Largest Share of the European Market9.3.2 Germany9.3.2.1 The Rapidly Growing Pharmaceutical Market is Expected to Drive Market Growth9.3.3 France9.3.3.1 Research Across All Industries is Strongly Supported By the Government9.3.4 Denmark9.3.4.1 Denmark has the Third-Largest Commercial Drug-Development Pipeline in Europe9.3.5 Switzerland9.3.5.1 Market Growth is Primarily Driven By the Well-Established Pharmaceutical & Biotechnology Industry in the Country9.3.6 Spain9.3.6.1 Spain has A Well-Established Network of Research Centers, Universities, and Hospitals, Which Form an Ideal Environment for Research9.3.7 Italy9.3.7.1 Growth in This Market is Mainly Driven By Increasing Life Science R&D in the Country, Funded By Both Public and Private Organizations9.3.8 Rest of Europe9.4 Asia Pacific9.4.1 Japan9.4.1.1 Large Number of Research Initiatives Towards the Development of Precision Medicine Supporting Market Growth9.4.2 China9.4.2.1 Growth in R&D to Enhance the Technological Capabilities in the Country, Thereby Driving the Demand for High-Quality Research Tools9.4.3 Australia9.4.3.1 Increasing Focus of the Healthcare System on Precision Medicine to Offer Significant Growth Opportunities9.4.4 India9.4.4.1 Increasing Pharma R&D and Government Funding in the Biotechnology Industry are the Major Factors Driving Market Growth9.4.5 Rest of Asia Pacific9.5 Latin America9.5.1 Strong Pharmaceutical Industry in the Region to Provide Significant Growth Opportunities9.6 Middle East and Africa9.6.1 Increasing Partnerships Among Global Players With Government Organizations in the Region to Support Growth

10 Competitive Landscape 10.1 Overview10.2 Market Share Analysis10.2.1 Synthetic Biology Market, By Key Players, 201810.3 Competitive Leadership Mapping10.3.1 Visionary Leaders10.3.2 Innovators10.3.3 Dynamic Differentiators10.3.4 Emerging Companies10.4 Competitive Situation and Trends10.4.1 Product Launches10.4.2 Expansions10.4.3 Acquisitions10.4.4 Other Strategies

11 Company Profiles 11.1 Thermo Fisher Scientific Inc.11.1.1 Business Overview11.1.2 Products Offered11.1.3 Recent Developments11.2 Merck KGaA11.3 Agilent Technologies Inc.11.4 Novozymes A/S11.5 Ginkgo Bioworks11.6 Amyris Inc.11.7 Intrexon Corporation11.8 Genscript Biotech Corporation11.9 Twist Bioscience11.10 Synthetic Genomics Inc. (SGI)11.11 Codexis Inc.11.12 Synthego Corporation11.13 Creative Enzymes11.14 Eurofins Scientific11.15 Cyrus Biotechnology Inc.11.16 Other Major Companies11.16.1 Atum11.16.2 Teselagen11.16.3 Arzeda11.16.4 Integrated DNA Technologies Inc.11.16.5 New England Biolabs

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