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Will Nanotechnology be Inserted into the COVID-19 Vaccine? Shocking Video from Famous Doctor – The Jewish Voice

§ October 17th, 2020 § Filed under Nanotechnology Journal Comments Off on Will Nanotechnology be Inserted into the COVID-19 Vaccine? Shocking Video from Famous Doctor – The Jewish Voice

Jared Evan

While we are constantly hearing from President Trump about the COVID vaccine, and the debate has been centered around how fast the vaccine will become available and if the public will trust the vaccine if it is quickly approved- nobody is actually reporting on the actual vaccine itself- how it works and what exactly will happen to our bodies upon taking the vaccine.

Scientific American reported: labs are turning to gene-based vaccines. Scientists use information from the genome of the virus to create a blueprint of select antigens. The blueprint is made of DNA or RNAmolecules that hold genetic instructions. The researchers then inject the DNA or RNA into human cells. The cells machinery uses the instructions to make virus antigens that the immune system reacts to. Cells respond to the instructions as a normal part of their daily existence. This is the same trait infectious viruses exploit; they cannot reproduce on their own, so they use a cells machinery to make copies of themselves. They burst out of the cell and infect more cells, widening the infection.

Some researchers insist DNA vaccines will genetically modify humans, many reputable scientists dispute this claim.

Reuters reported in a fact check: A future COVID-19 vaccine will not genetically modify humans. DNA vaccines do not integrate the virus DNA into the cell nucleus of its recipient but instead inject part of the virus DNA/RNA into tissues to stimulate an immune response in the body.

There is another factor that has been injected into the discussion. Nanotechnology

From lexico.com: nanotechnology: The branch of technology that deals with dimensions and tolerances of less than 100 nanometers, especially the manipulation of individual atoms and molecules.

A quote from Frontiers in Immunology, January 24, 2019, Nanoparticle-Based Vaccines Against Respiratory Viruses: A new generation of vaccines based on nanoparticles has shown great potential to address most of the limitations of conventional and subunit vaccines. This is due to recent advances in chemical and biological engineering, which allow the design of nanoparticles with precise control over the size, shape, functionality and surface properties, leading to enhanced antigen presentation and strong immunogenicity.

The concept of inserting nanoparticles or nanotechnology into a cutting edge vaccine is not a creative conspiracy theory, evidently.

Blogger Jon Rappoport pointed out another scientific paper on this technology:

Frontiers in Immunology, October 4, 2018, Nanoparticle Vaccines Against Infectious Diseases: In the last several years, the use of nanoparticle-based vaccines has received a great attention to improve vaccine efficacy, immunization strategies, and targeted delivery to achieve desired immune responses at the cellular levelNanocarriers composed of lipids, proteins, metals or polymers have already been usedThis review article focuses on the applications of nano carrier-based vaccine formulations and the strategies used for the functionalization of nanoparticles to accomplish efficient delivery of vaccines in order to induce desired host immunity against infectious diseases.

Here is where this starts to sound like a science fiction movie.

A 2019 paper from science journal Nano Today titled: Nanowire probes could drive high-resolution brain-machine interfaces.

advances can enable investigations of dynamics in the brain [through nano-sensor-implants] and drive the development of new brain-machine interfaces with unprecedented resolution and precision.

output electrical signals of brain activity or input electrical stimuli to modulate brain activity in concert with external machines, including computer processors and prosthetics, for human enhancement

Can it be possible that we will literally be connected to a computer via nanotechnology?

Christiane Northrup, a famous Obstetrician, and best-selling author think so. In this shocking video- the claims that she makes are mind-blowing and alarming.

After some research, I can not verify for a fact that nanoparticles will be in the COVID vaccines, however, I found the following from Mirror Review magazine, from an article called: Bill Gates Partners DARPA For New DNA Nanotech COVID-19 Vaccine

There is a spreading fire about the fact thatBill Gateshas teamed up with the Department of Defense and DARPA, which is the special project research and development arm of the Pentagon. The team-up was a call to develop a brand new type of vaccine which is being rushed into production, an alarm for med-industry benefits.

Especially considering this new kind of DNA / RNA vaccine would normally take 15-20 years to roll out, while this one is being rolled out in a matter of months and is already undergoing human clinical trials. The urgency and rolled back regulations to streamline this new vaccine is, of course, justified by the crisis.

Will these nanoparticles be inserted into millions upon millions of people around the globe? I do not know, however, the technology is there, it exists and this is not some far fetched conspiracy theory.

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When is a patent price ever unfairly high? | OUPblog – OUPblog

§ October 17th, 2020 § Filed under Nanotechnology Journal Comments Off on When is a patent price ever unfairly high? | OUPblog – OUPblog

The boundaries between patent and antitrust are never crystal clear.Part of the confusion comes from patent laws historical monopoly roots. In early seventeenth-century England, those letter patents that originated from meritorious artisans grants in Renaissance Venice took an upsetting twist and degraded into a royal privilege to monopolize trades by those favored by the Crown. This historical entanglement left unfortunate space for confusion to grow throughout the centuries afterward. Further complicated with the fluctuating landscape change of antitrust itself, properly delineating the intersection of antitrust and patent has become a challenge faced by most competition law authorities worldwide, particularly when it comes to the current innovative economy and the necessary paradigm shift it legitimately demands.

Such challenge is no less acute in contemporary China. In fact, it is arguably more difficult because of Chinas own historical complications, and the seemingly dramatic tension thus forged with a burgeoning economy today.Starting in 1978, the glorious economic reform of this young ancient country, essentially the aspired transition from a wholly controlled regime to a reasonably fledged innovative market economy, albeit with socialist characteristics, is still on its strenuous way. All kinds of obstacles need to be overcome along the way, ranging from formal restraints in laws and infrastructure, to lingering outdated theories that remain powerful impediments. On the other hand, to quickly adapt and facilitate the distinctive features of an innovative market economy, Chinese anti-monopoly (AML) authorities equally need to accomplish a static-dynamic paradigm shift. This shift would be partially addressed by an in-depth understanding of the sophisticated interplay between antitrust and intellectual property (IP).

A curious thread of this intersection tapestry is the concept of unfairly high patent pricing under the AML. In contrast to US antitrust but not facially dissimilar to EU competition law, the AML forbids a dominant undertaking from abusing its market position by selling at unfairly high prices. However, neither the anti-monopoly statute nor its practical guidelines gave an administrative definition to this key concept. Correspondingly, courts and AML authorities have striking discretion in characterizing a market price as unfairly high, potentially exposing the undertaking to harsh penalties. Two recent landmark cases with a key allegation of unfairly high patent pricing are the2015 decision against Qualcomm Inc.by the National Development Reform Commission, and anongoing investigation against Ericssonby the new authority (established in April 2018),State Administration for Market Regulation.

Section 55 of the AML arguably constitutes an IP safe harbor, providing that aproper exerciseof Intellectual Property Right (IPR ) shall be immune from scrutiny, while anabuse, excluding or restricting competition shall not. Despite the statutory framework, several recent cases have indicated a seemingly substantial departure in practice from this competition harm-focused approach, which generally use a more simplistic benchmark comparison methodology. This rough observation has been further supported by the newly passed agency regulation, i.e.Anti-monopoly Guidelines for IP(passed in January 2019, and published in August 2020).

Casting political economic arguments aside, one crucial reason for this departure is the lack of systematic understanding of the patent-antitrust interplay. Ambiguity lies in two aspects. One, due to the very patent mechanism in fostering innovation, even a proper exercise of right would necessarily restrict certain types of competition. Thus, it seems that an over-general standard of whether to eliminate or restrict competition cannot work as the ultimate test to differentiate abuse from legitimate exercise. Two, despite extensive use of patent abuse worldwide, the exact contour of this concept remains equally elusive. Resorting solely to the various constructions in comparative law, helpful as it is, cannot resolve these ambiguities adequately. To assess the interplay, we must not dodge the question of whether an act, such as the alleged unfairly high patent pricing, falls outside the scope authorized by Chinese patent law, in that it not only restricts competition, but also in a way that departed from what patent law has contemplated.

In a nutshell, the patent regime promotes innovation essentially through the instigation ofdynamic competition.Specifically, it (1) bridges an innovators R&D to market demands: the better aligned a new technology to consumer needs, the more valuable this shell of right would become in the marketplace, thereby resulting in higher profit an innovator can harvest by excluding imitating competitors (competition by imitation, orCBI); (2) by restrictingCBIwith reasonably tailored claims, patent law simultaneously induces social resources into inventing around activities, i.e. to provide better/cheaper substituting technologies, thereby encouragingcompetition by substitution(CBS). In certain circumstances, the fruits of suchCBSmay also be protectable with new property right, such as the case of blocking patents, which would likely reduce the earlier patentees market power against the competitor; and (3) feeling pressure ofCBS, the earlier innovator would likely be incentivized to continue her further inventing around, striving to stay a winner in the marketplace. In this way, a virtuous circle ofdynamic competitionmay come into force.

Notably, a critical link of this circle pivots on theCBSprecisely through the restriction uponCBI.This recognition has important implications in practice. For example, if an alleged patent price merely caused restriction onCBIas indicated in a supra-competitive profit, the AML must refrain from intervening. Instead, the focus should be on whether the questioned act restricts upon theCBS. A showcase of the CBS foreclosure is the historical deadlock between the famous Marconi diode and the Lee De Forest triode patent during early development of radio technology. The radical improvement as represented by the triode invention, even though literally infringing on the pioneer Marconi patent, is exactly the type of creative destruction Joseph Schumpeter once emphasized that boosts innovation.

Despite much sophisticated discussion of such theoretical worry however, decades of empirical research have showed insubstantial success in proving CBS foreclosure caused by excessive patent pricing in marketplace. A concurrent example for this disintegration is the robust innovation of the standard essential patent intensive industries, in the shadow of persistent royalty stacking prediction. An informed speculation is that precisely because theCBSlink is pivoted by patent regime instigatingdynamic competition, throughout ages the law has developed an implicit awareness, as well as multiple policy levers to safeguard theCBSfrom being lightly disrupted.

Judge Easterbrook once noted that antitrust is costly and the cost comes largely from judicial ignorance of business practices. In China today such ignorance is even intensified by policy makers divergent understandings of the governments role in a market economy, as embodied in the2016 Lin Yifu-Zhang Weiying Debatethat drew an audience worldwide. Considering our meager knowledge of dynamic efficiency and innovation, as well as the low likelihood of dynamic competition suppression by high patent pricing in existing empirical research, it would be wise for the AML authorities to refrain from calling a patent pricing unfairly high, until the plaintiff proves otherwise with real evidence rather than theoretical conjectures.

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Swiss scientists fight food waste at the nano level – swissinfo.ch

§ October 11th, 2020 § Filed under Nanotechnology Journal Comments Off on Swiss scientists fight food waste at the nano level – swissinfo.ch

Every year, around 1.3 billion tonnes of food goes to waste worldwide. In Switzerland researchers are trying to help tackle the food waste challenge using nanotechnology.

Tara Giroud

It can happen to anyone - a yogurt at the back of your refrigerator has passed its best-before date and you end up throwing it in the garbage or compost. But was it actually ok to eat?

The best-before quality recommendation stamped on food can be confusing for consumers. Perhaps the food in that particular package was perfectly safe and tasty. And by ending up in the bin unnecessarily, it simply added to the mountains of food waste.

According to the Food and Agriculture Organization of the United Nations (FAO), roughly one-third of all food produced every year is wasted or lostfrom farms to shops to caterers to households. Switzerland is a major culprit: 190 kilos of food is wasted per person annually.

Niloufar Sharif believes she might have an answer to this problem. The Iranian post-doctoral researcher is working on a three-year project at the Federal Institute of Technology Lausanne (EPFL) to develop intelligent packaging technologies that can precisely identify which products are spoiled.

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When we have sensors, then we can monitor the real-time product, the food scientist told swissinfo.ch.

In her nanotechnology lab at the EPFL, Sharif is building sensors from miniscule carbon nanotubes, cylindrical molecules consisting of rolled-up sheets of single-layer carbon atoms measuring one billionth of a metre, which she hopes will be useful for detecting signs of food degradation.

These ultra-tiny sensors, integrated into food packaging, react when food goes off. A system then interprets the data and translates it into a sign people can read on the outside of the food package.

Different foods decompose in different ways, at various rates and under different conditions, such as light and moisture levels. Sharif believes her sensors can react to certain gases during bacterial or fungal activity on the food.

One way it can do this is by monitoring pH levels, which tell if something is acidic, neutral or alkaline, and can indicate food decomposition.

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If we have a product in which there is no microorganism activity, we may have, for example, a pH of 7 [which is in the middle or neutral], Sharif said. When we have activity of microorganisms, this pH will change. If this sensor detects changes of the pH, it alerts us to some kind of activity of microorganisms.

If the pH moves into unsafe territory, a sensor on the label alerts food managers or shoppers that the food is no longer safe to eat.

Sharifs project was selected as part of theFuture Food Initiative, a Swiss science-industry programme that aims to expand research and education in the area of food and nutrition.

Although her work has been delayed due to the coronavirus pandemic, she is now busy setting up the lab for the first of the projects three phases: testing the sensors with various gases, integrating the sensors into packaging materials, and testing on actual food.

Another recent food waste project in Switzerland used nanotechnology to make smart packaging possible. It was completed in 2018 as part of Switzerlands National Research Programme NRP 69, Healthy Nutrition and Sustainable Food Production.

In the University of Basels chemistry department, Professor Cornelia Gabriela Palivan and Ozana Fischer developed small glass surfaces to which they attached minuscule capsules, measuring just 100 nanometres in diameter, or 1,000th the width of a human hair.

The tiny capsules can be filled with different substances for various uses. The simplest, Palivan said, is as a reactor that can indicate when an environment has changed, such as when the quality of food deteriorates.

With the sensors, you will see a presence of specific molecules that are associated with food degradation, she told swissinfo.ch.

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To test their research, the scientists filled capsules with the fluorescent dye pyranine. As the pH level of their environment changed, the intensity of pyranines fluorescence varied.

In other scenarios, the capsule could be designed to detect a specific harmful substance. Once detected, a gate would open allowing the harmful substance into the capsule where it would interact with a substance already inside the capsule rendering it harmless.

Consumers would see a square label about 0.5 cm in size that would change in colour to indicate freshness. This could look like a traffic light, where a green label means the food inside is fresh and a red label would indicate that the product is no longer safe to eat.

The Basel team published their findings in the Swiss chemistry journal Helvetica Chimica Acta in 2018.

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For Palivan, if people do start to call for changes, results like her groups work are ready to show what can be done.

In research we are developing new technology, therefore we have a solution, she said. If society needs them, we can go ahead, but we need more support.

Karin Spori, managing director of foodwaste.ch, a Bern-based non-profit organisation, said it was interesting to see the ideas researchers are bringing to the table.

She imagined that industry, such as chefs or food donation centres, could make use of a system like the one Palivan and her team developed.

But the trained biologist felt less confident about its use at the consumer level. She said people may not want something called nanotechnology affiliated with their food.

Spori said changes in households are more likely by educating consumers to trust their sense of smell and taste for freshness and to manage how they buy and use food.

Smart packaging doesnt make me smart if I dont organise my food properly, Spori said.

She added that in industrialised countries like Switzerland, theres little pressure to change how consumers approach their own food waste.

Seven percent of the household budgets are for food in Switzerland, a small amount, Spori said.

The Swiss consumers mentality is often that, when a yogurt doesnt look so fresh, you can just buy a new one, she added.

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Researchers Use Charged Nanoscale MOFs and X-Rays to Kill Cancer Cells – AZoNano

§ October 6th, 2020 § Filed under Nanotechnology Journal Comments Off on Researchers Use Charged Nanoscale MOFs and X-Rays to Kill Cancer Cells – AZoNano

Written by AZoNanoOct 5 2020

The heterogeneity of cancer cells themselves is one of the main difficulties faced in the development of effective and targeted treatments for cancer. This change makes it hard for the immune system to identify, react to, and actively fight against tumors.

But new advances in the field of nanotechnology are currently rendering it feasible to provide targeted and personalized vaccines to treat cancer.

A new study, reported recently in the Science Advances journal, describes the use of charged nanoscale metal-organic frameworks and X-rays to produce free radicals inside tumor tissue to directly destroy the cancer cells.

Moreover, it is possible to use the same frameworks to provide immune signaling molecules called PAMPs to trigger the immune response against tumor cells. By integrating these two methods into one vaccine that can be easily administered, this new technology could pave the way to improve local and systemic treatment of cancers that are hard to treat.

As part of a collaboration between the Lin Group from the Department of Chemistry at the University of Chicago and the Weichselbaum Lab at the University of Chicago Medicine, the researchers combined expertise from cancer biology and inorganic chemistry to address the challenging issue of correctly targeting and triggering an innate immune response against cancer.

This study took advantage of the special properties of nanoscale metal-organic frameworks (nMOFs), which are nanoscale structures made of recurring units arranged in a lattice formation and with the ability to infiltrate tumors.

Such nMOFs can be irradiated with the help of X-rays to produce high concentrations of free oxygen radicals, thereby directly killing the cancer cells and generating inflammatory molecules and antigens helping the immune system identify and clear cancerous cells, quite similar to a vaccine.

Moreover, the lattice-like structure of the nMOFs makes them ideal transporters to directly deliver anti-cancer drugs to tumors. But to date, it has been challenging to trigger innate and adaptive immune responses essential for destroying cancerous tumors.

As part of the new research, the team further refined their technique. They produced a new kind of nMOF structure that can be loaded with drugs called pathogen-associated molecular patterns (PAMPs).

Upon applying the nMOFs to cancerous tumors, irradiation of the tissue had a double impact: it activated the nMOFs to destroy local cancer cells to create antigens against the tumor and discharged the PAMPs, which subsequently triggered a much more powerful activation of the immune response to the tumor antigens.

This one-two punch could destroy both pancreatic and colon cancer cells with high efficacy, even in tumor models that are considerably resistant to other types of immunotherapy.

The investigators performed additional experiments with mice and observed that they could expand the impacts of the nMOFs even to distant tumors by applying checkpoint inhibitors, offering new hopes for treating cancer both systemically and locally with this method.

By including PAMP delivery with the nMOFs, this is the first time we were able to really enhance the immune response to the antigens. This is entirely different from all of our previous studies because weve shown that the nMOFs plus PAMPs can impact all of the aspects required for activating the immune system.

Wenbin Lin, PhD, Study Senior Author and James Franck Professor of Chemistry, University of Chicago Medical Center

We can use this nanoformulation to enable personalized cancer vaccinations that will work on any patient because this strategy will not be subject to the heterogeneity we see among different patients, added Lin.

The impacts of the treatment were so marked that the scientists are keen to bring the technology to clinical trials, whereas the other versions of the nMOF technology are already being tested, with encouraging results until now.

The brilliance of this system is twofold. First, it can improve local tumor control by increasing the killing power of X-rays. Second, while there has been interest in using radiation to stimulate the immune response to fight cancer, it has turned out to be harder than we thought.

Ralph Weichselbaum, MD, Study Co-Author and Daniel K. Ludwig Distinguished Service Professor of Radiation and Cellular Oncology, University of Chicago Medical Center

In this case, the nMOFs are able to activate the innate and adaptive immune systems, which makes this technology very promising for treating cancer in the clinic, added Weichselbaum, who is also the Chair of the Department of Radiation and Cellular Oncology at UChicago.

The investigators are already looking forward to next steps and striving to fine-tune the technology. Were refining the design of the nMOF and its delivery of the PAMPs, in preparation for testing it in humans, stated Lin. Were really working on zooming in on the best formulation so we can get this into clinical trials, hopefully in the next two to three years, or even sooner.

The researchers acknowledge the interdisciplinary and collaborative nature of UChicago and the University of Chicago Medicines Hyde Park campus for making a space where cancer biology and chemistry have combined to create such an encouraging potential therapy, as well as the support they have received from Ludwig Cancer Research along the way.

From the conception of this project and getting it funded to starting with clinical trials where were able to test the technology in clinical trials and get real patient data, this work has all been done right here at UChicago. We really are going from discovering something in the lab to testing it at the bedside.

Ralph Weichselbaum, MD, Study Co-Author and Daniel K. Ludwig Distinguished Service Professor of Radiation and Cellular Oncology, University of Chicago Medical Center

The study titled Nanoscale metal-organic frameworks for x-ray activated in situ cancer vaccination was financially supported by the National Cancer Institute (U01-CA198989 and 1R01CA253655), the Department of Defense (PC170934P2), the University of Chicago Medicine Comprehensive Cancer Center (NIH CCSG: P30 CA014599), and the Ludwig Institute for Metastasis Research.

The additional authors of the study are Kaiyuan Ni, Guangxu Lan, Nining Guo, August Culbert, Taokun Luo, and Tong Wu of the University of Chicago.

Ni, K., et al. (2020) Nanoscale metal-organic frameworks for x-ray activated in situ cancer vaccination. Science Advances. doi.org/10.1126/sciadv.abb5223.

Source: https://www.uchicagomedicine.org/

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Connected PPE and new ways to assess health and performance – Innovation in Textiles

§ October 6th, 2020 § Filed under Nanotechnology Journal Comments Off on Connected PPE and new ways to assess health and performance – Innovation in Textiles

Myant Inc., a global pioneer in textile computing, has unveiled concept designs for connected PPE that utilize VOC sensing, enabling new ways of holistically assessing health and performance as part of an expanding interconnected system of biometric garments being realized by the company.

As the idea of wearing PPE evolved from a reactionary preventative measure to an integral part of daily living in the post-COVID world, Myant began to envision ways that a connected biometric sensing mask could integrate into the companys broader vision for Skiin a network of interconnected biometric garments that span across the different spheres of life.

By virtue of being in close proximity to the nose and mouth, the mask form factor presents an opportunity for a connected textile to collect data on emissions from the respiratory system via volatile organic compound (VOC) sensing, providing new ways to assess health and performance for the user, Myant explains.

The three patent pending mask concepts, designed for healthcare, fitness, and workplace use cases, serve as a guiding vision for the development of the companys first connected biometric mask to be commercialized later this year under Myants consumer brand Skiin.

According to Myant, this development points the way towards a future where functionalized textiles and garments are pervasive throughout daily life, acting as a continuous ambient interface to the human body that helps all people in society live healthier, higher performance, safer, and more productive lives.

Protecting in new ways with connected biometric sensing PPE

The connected mask concepts are modular by design, featuring an N95-level filtration layer positioned on top of a nose-bridge that separates airflow coming from the nose and the mouth, and a flexible silicone seal. The components are held in place by a knitted textile cover that includes heated yarns and electrostatic yarns that enhance protection against infectious agents, as well as temperature sensing yarns that enable sensing of respiration rate.

These yarns draw power through conductive yarns that connect to a module which sends data via BLE to the users nearby mobile device. Additional sensing is enabled through integrated VOC sensor, sweat and saliva sensor, carbon dioxide sensor (enabling V02 Max measurement for the fitness mask), an in-ear IR sensor (for body temperature measurement), and a PPG sensing ear clip (for HRV and SpO2). The modular design also allows for rapid disassembly and cleaning via hand washing, use of disinfecting sprays, or autoclaving, adds Myant. Data captured by the mask is sent to the Myant Platform where it, along with other data captured by garments powered by Skiin, are holistically assessed by AI to generate meaningful insights to improve health and performance.

Myant says that the addition of biochemical sensing rounds out its existing biometric sensing capabilities (biomechanics, electrophysiology, haemodynamics, and now biochemistry), enabling textiles that are powered by Skiin to provide an even more comprehensive view into the human body across different spheres of life, including within healthcare, fitness, and workplace settings. Myant has developed three concept designs mapping to these applications that will serve as a guide in its development of a consumer-ready connected biometric mask to be launched in Q4 2020 under its connected clothing brand Skiin.

Connected PPE for protection and biometric monitoring in healthcare settings

This connected biometric PPE concept was designed for healthcare settings like clinics or hospitals where care providers, patients and their loved ones all benefit from protection and biometric monitoring. Every person inside a medical setting is a potential source of infection, Myant explains, and the ubiquity of masks makes them an ideal way to create a comprehensive view of the collective and individual health of a healthcare facility.

With integrated VOC sensing to detect airborne infectious agents being emitted from the users respiratory system, an in-ear infrared (IR) sensor to provide accurate continuous tracking of body temperature, temperature sensing yarns that captures respiration, and an ear-clip with an integrated PPG sensor to track SpO2 and HRV, the connected mask becomes a powerful tool to understand what is happening inside the patient or the care providers body, the company adds.

All sensors draw power through conductive yarns in the textile from a Skiin pod (common amongst all garments that are powered by Skiin) which communicates with a nearby mobile device via BLE. The data is then sent to the Myant Platform which uses AI to triage the set of biometric symptoms to look for early signs of infection, enabling a more predictive approach to care. These medical-grade masks are knitted to meet N95 standards and are modular in design, allowing for individual parts to be wiped down, sprayed, or autoclaved.

Connected PPE that improves rather than hinders performance

The conversation around wearing a mask while exercising has largely been a discussion about which masks are least impactful on the users performance, Myant comments. Researchers from the University of Leipzig in Germany conducted a prospective cross-over study to investigate the impact of N95 and surgical masks on heart/lung responses of subjects during an incremental cycling test to exhaustion, concluding that ventilation, cardiopulmonary exercise capacity and comfort are reduced by surgical masks and highly impaired by N95 face masks in healthy individuals, Myant explains.

Another study published in the British Journal of Sports Medicine suggests that air-flow restricting masks can increase the rate of perceived exertion and decrease performance during resistance training, Myant adds.

Accordingly, with masks becoming an unavoidable part of all spheres of life, including fitness, Myant looked for ways to not only address these issues but to use masks to actually improve performance instead of hindering it.

Myant continues: One way this concept mitigates the impact of masks on performance is through the modular design, featuring a nose-bridge that isolates the nasal and oral airflows, reducing the recycling of oxygen depleted exhaled air back into the system. The silicone seal around the nose and mouth allows the mask to not only protect but function as a way to capture data about the cardiovascular performance of the athlete through measurement of VO2 max and RER monitoring (respiratory exchange ratio).

In addition to these biochemical sensing capabilities, Myant explains, mbedded IMU sensors on the Skiin pod create an accurate depiction of the athletes biomechanical activity while PPG sensing helps track heart rate before, during and after exercise. All this data lives on the Myant Platform where it can be assessed holistically by AI to uncover insights that could improve performance. Data can even be shared with training partners and coaches who can help inspire the athlete to unlock new levels of performance.

Connected PPE to keep workplaces safe and productive

This connected PPE concept was designed with the workplace in mind where a balance between safety and productivity is essential. Since the cost of outbreak can be devastating for both employees and employers, it is incumbent on all stakeholders to ensure that everyone is properly protected, to mitigate risk of exposure, and to remain vigilant for the early signs of infection, Myant articulates.

One common complaint about wearing masks amongst workers, Myant claims, is that recycling of air (or breathing air that has been exhaled but trapped inside a mask) leads to workers complaining about fatigue. This mask attempts to address the concern by separating the oral and nasal airflows via the nose-bridge, ensuring that air exhaled from the mouth is not recycled into the body. The N95 filtration level of the textile combined with VOC sensors to identify potential airborne infectious agents and heated yarns that promote the release of ions from copper yarns (known to be detrimental to viruses) all help to provide increased protection, the company adds. The addition of stress sensing, fatigue monitoring, respiration, body temperature and other biometric readings helps to identify early signs of an outbreak that could potentially gravely impact the health, well-being, and productivity of the workforce, Myant concludes.

Further information

Milad Alizadeh-Meghrazi, MASc, PhD (c)

Vice President of Research, Development and Partner Integration @ Myant

[emailprotected]

Ilaria Varoli

Executive Vice President

[emailprotected]

http://www.myant.ca

http://www.skiin.com

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Plus Therapeutics Announces Brain Cancer Clinical Advisory Team – GlobeNewswire

§ October 2nd, 2020 § Filed under Nanotechnology Journal Comments Off on Plus Therapeutics Announces Brain Cancer Clinical Advisory Team – GlobeNewswire

October 02, 2020 07:00 ET | Source: Plus Therapeutics Inc.

AUSTIN, Texas, Oct. 02, 2020 (GLOBE NEWSWIRE) -- Plus Therapeutics, Inc. (Nasdaq:PSTV) (the Company), today announced the appointment of five leading experts in the fields of neurological surgery and neuro-oncology to its Clinical Advisory Board (CAB). The CAB will advise the Company as it advances its nanoscale radiotherapeutics to treat rare brain and neurological cancers.

To successfully bring our investigational RNL drug through the clinical development process, we will need distinguished scientists and physicians standing with us, that have unique perspectives and an intimate understanding of the key clinical issues, said Marc H. Hedrick, M.D., President and Chief Executive Officer of Plus Therapeutics. These doctors are leaders in their fields and will be important to our efforts on behalf of the patients with glioblastoma.

New members of Plus CAB include:

Manish Aghi, M.D., Ph.D., Professor, Neurological Surgery, at the Weill Institute for Neurosciences at the University of California, San Francisco.

Dr. Manish Aghi is a neurosurgeon, scientist and current faculty member in the department of neurological surgery and graduate division of biomedical sciences, as well as a principal investigator in the Brain Tumor Research Center at UCSF. He completed his MD-PhD Program through the Medical Scientist Training Program at Harvard Medical School, followed by neurological surgery residency and postdoctoral training at Massachusetts General Hospital. Dr. Aghi serves as principal investigator on multiple industry sponsored and investigator-initiated Phase 1-2 clinical trials comparing immunotherapy versus anti-angiogenic therapy of recurrent glioblastoma, as well as investigating convection-enhanced delivery of oncolytic viruses and nanoliposomal chemotherapy to recurrent glioblastoma.

Nicholas Butowski, M.D., Professor, Neurological Surgery and Director, Translational Research, Neuro-Oncology at the Weill Institute for Neurosciences at the University of California, San Francisco.

Dr. Butowski is a neuro-oncologist who specializes in brain tumors, neuroimaging, cognitive and rehabilitative neurology, and complementary therapies for neurological disorders. He is director of clinical services in neuro-oncology and a co-investigator of National Cancer Institute-supported North American Brain Tumor Consortium clinical trials. Dr. Butowski earned his medical degree at the University of Illinois at Chicago and completed a residency in neurology and a fellowship in neuro-oncology at UCSF. He is a member of the American Academy of Neurology, American Society of Clinical Oncology and Society for Neuro-oncology.

Russell Lonser, M.D., Professor and Chair, Department of Neurological Surgery at The Ohio State University Wexner Medical Center.

Dr. Lonser is a professor and chair of the Department of Neurological Surgery at The Ohio State University Wexner Medical Center, and currently holds the Dardinger Family Chair in Neurosurgical Oncology. Previously, he was chief of the Surgical Neurology Branch at the National Institutes of Health. Dr. Lonser specializes in the resection of brain, spinal cord, pituitary and brainstem tumors. He is a director on the American Board of Neurological Surgeons, and was the head of the research subcommittee in Head, Neck and Spine Injury Committee for the National Football League. Dr. Lonser has served on the editorial boards of NEUROSURGERY, World Neurosurgery, Journal of Neurosurgery, PLoS One and Science Reports.

Alireza Mohammadi, M.D., Neurosurgeon at Cleveland Clinic Lerner College of Medicine of Case Western Reserve University.

Dr. Mohammadi is a board-certified neurosurgeon who specializes in neurosurgical oncology including surgery and laser ablation of brain tumors as well as radiosurgery for brain and spine. He is currently practicing at Neurosurgery Department and the Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center at the Cleveland Clinic. Since 2014, Dr. Mohammadi has also served as an assistant professor in Neurological Surgery at the Cleveland Clinic Lerner College of Medicine. Dr. Mohammadi earned his medical degree from Tehran University School of Medicine in Tehran, Iran. After completing his residency in neurosurgery at Shohada Hospital, he went on to complete his fellowship in neuro-oncology surgery and his fellowships in radiosurgery at the Cleveland Clinic.

Michael Vogelbaum, M.D., Ph.D., Chief of Neurosurgery and Program Leader of the Department of Neuro-Oncology at Moffitt Cancer Center.

Dr. Vogelbaum is an internationally known leader in neurosurgical oncology and distinguished investigator in laboratory research, translational and clinical trials in gliomas. He is currently Chief of Neurosurgery and Program Leader of the Department of Neuro-Oncology at Moffitt Cancer Center.Dr.Vogelbaum is also the inventor of patented medical devices for delivering therapeutics directly to the brain and brain tumors, with the first of these devices having received U.S. Food and Drug Administration clearance. After completing his M.D. and Ph.D. (Biomedical Engineering) at the University of Virginia, Dr. Vogelbaum completed his residency in neurological surgery at Barnes-Jewish Hospital in St. Louis, Mo.

About Plus Therapeutics, Inc.

Plus Therapeutics (Nasdaq: PSTV) is a clinical-stage pharmaceutical company whose radiotherapeutic portfolio is concentrated on nanoliposome-encapsulated radionuclides for several cancer targets. Central to the Companys drug development is a unique nanotechnology platform designed to reformulate, deliver and commercialize multiple drugs targeting rare cancers and other diseases. The platform is designed to facilitate new delivery approaches and/or formulations of safe and effective, injectable drugs, potentially enhancing the safety, efficacy and convenience for patients and healthcare providers. More information may be found atplustherapeutics.com and respect-trials.com.

Cautionary Statement Regarding Forward-Looking Statements

This press release contains certain statements that may be deemed forward-looking statements within the meaning of U.S. securities laws. All statements, other than statements of historical fact, that address activities, events or developments that we intend, expect, project, believe or anticipate and similar expressions or future conditional verbs such as will, should, would, could or may occur in the future are forward-looking statements. Such statements are based upon certain assumptions and assessments made by our management in light of their experience and their perception of historical trends, current conditions, expected future developments and other factors they believe to be appropriate. These statements include, without limitation, statements about: the Companys potential to facilitate new delivery approaches and/or formulations of safe and effective, injectable drugs, potentially enhancing the safety, efficacy and convenience for patients and healthcare providers; the Companys potential to develop drug candidates currently in its product pipeline; and the Companys potential to develop additional drugs outside of its current pipeline. The forward-looking statements included in this press release are subject to a number of additional material risks and uncertainties, including but not limited to: the risk that the Company is not able to successfully develop product candidates that can leverage the U.S. FDAs accelerated regulatory pathways; and the risks described under the heading Risk Factors in the Companys Securities and Exchange Commission filings, including in the Companys annual and quarterly reports. There may be events in the future that the Company is unable to predict, or over which it has no control, and its business, financial condition, results of operations and prospects may change in the future. The Company assumes no responsibility to update or revise any forward-looking statements to reflect events, trends or circumstances after the date they are made unless the Company has an obligation under U.S. federal securities laws to do so.

Investor Contact Peter Vozzo Westwicke/ICR (443) 377-4767 Peter.Vozzo@westwicke.com

Media Contact Terri Clevenger Westwicke/ICR (203) 856-4326 Terri.Clevenger@westwicke.com

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Parents Trust the Doctor-Certified AM99 Mask to Protect Their Children for Its Ability to Deactivate COVID-19 on Contact – Press Release – Digital…

§ September 30th, 2020 § Filed under Nanotechnology Journal Comments Off on Parents Trust the Doctor-Certified AM99 Mask to Protect Their Children for Its Ability to Deactivate COVID-19 on Contact – Press Release – Digital…

Doctor-certified and rigorously tested across several international standards, the AM99 face mask is the next generation of face mask that employs superior proprietary antiviral nanotechnology and is hand-washable and more comfortable than other alternatives.

SAN FRANCISCO - September 30, 2020 - (Newswire.com)

As schools across the country wrestle with how to minimize COVID-19s impact with school in session, other parents can take more decisive action with the AM99face mask, developed by MindBeauty. The AM99face mask holds a number of certifications for its proprietary nanotechnology that is proven to deactivate COVID-19, among many other harmful pathogens, on contact. Its durability and unique antiviralproperties that allow the mask to stay sanitaryfor longer than any other material makethe AM99face mask the ideal choice for parents this school year.

AM99 has been tested according to lab standards from around the globeto ensure and prove its effectiveness against harmful pathogens,several of which are readily available on the AM99website. The AM99 face mask is also doctor-certified, making it a clear front-runner versus independent vendors and solopreneurs looking to capitalize on an exploding personal protective equipment (PPE) market.

Its the same mask I use in my everyday life, saysJoei Lau, founder of AM99. Not only is the AM99face mask backed by thousands of hours of research and approved by countless doctors, but it was designed with comfort and practicality in mind.

AM99masks are laboratory-certified to protect against the COVID-19 and other potentially harmful microorganisms including MRSA, E. coli, Klebsiella pneumoniae, to name a few. The cotton-based antimicrobial fabric keeps the masksanitary longer and is washable up to 70 times while maintaining its powerful antimicrobial efficacy. This makes the masks a more cost-effective, less wastefuland more comfortable alternative todisposable masks.

Rest easy knowing children are protected and comfortableand wearing a mask that stays clean longerwhen they return to school.

About AM99

MindBeauty created the AM99 line of protective face masks as a response to the heightened need for simple and effective solutions to contain, protect against and minimize the effects of the global outbreak. The result is a reusable face mask that is an effective, safe and fashionable option thats early-to-market for users and outperforms other masks in the market landscape. Learn more at am99tech.com.

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Dynamic tattoos promise to warn wearers of health threats – Jacksonville Journal-Courier

§ September 24th, 2020 § Filed under Nanotechnology Journal Comments Off on Dynamic tattoos promise to warn wearers of health threats – Jacksonville Journal-Courier

Carson J Bruns, University of Colorado Boulder

(The Conversation is an independent and nonprofit source of news, analysis and commentary from academic experts.)

Carson J Bruns, University of Colorado Boulder

(THE CONVERSATION) In the sci-fi novel The Diamond Age by Neal Stephenson, body art has evolved into constantly shifting mediatronic tattoos in-skin displays powered by nanotech robopigments. In the 25 years since the novel was published, nanotechnology has had time to catch up, and the sci-fi vision of dynamic tattoos is starting to become a reality.

The first examples of color-changing nanotech tattoos have been developed over the past few years, and theyre not just for body art. They have a biomedical purpose. Imagine a tattoo that alerts you to a health problem signaled by a change in your biochemistry, or to radiation exposure that could be dangerous to your health.

You cant walk into a doctors office and get a dynamic tattoo yet, but they are on the way. Early proof-of-concept studies provide convincing evidence that tattoos can be engineered, not only to change color, but to sense and convey biomedical information, including the onset of cancer.

Signaling biochemical changes

In 2017, researchers tattooed pigskin, which had been removed from the pig, with molecular biosensors that use color to indicate sodium, glucose or pH levels in the skins fluids.

In 2019, a team of researchers expanded on that study to include protein sensing and developed smartphone readouts for the tattoos. This year, they also showed that electrolyte levels could be detected with fluorescent tattoo sensors.

In 2018, a team of biologists developed a tattoo made of engineered skin cells that darken when they sense an imbalance of calcium caused by certain cancers. They demonstrated the cancer-detecting tattoo in living mice.

UV radiation sensors

My lab is looking at tech tattoos from a different angle. We are interested in sensing external harms, such as ultraviolet radiation. UV exposure in sunlight and tanning beds is the main risk factor for all types of skin cancer. Nonmelanoma skin cancers are the most common malignancies in the U.S., Australia and Europe.

To help address this problem, we developed an invisible tattoo ink that turns blue only in UV light, alerting you when your skin needs protection. The tattoo ink contains a UV-activated dye inside of a plastic nanocapsule less than a micron in diameter or thousandth of a millimeter about the same size as an ordinary tattoo pigment.

The nanocapsule is needed to make the color-changing tattoo particles large enough. If tattoo pigments are too small, the immune system rapidly clears them from the skin and the tattoo disappears. They are implanted using tattoo machines in the same way as regular tattoos, but they last for only several months before they start to degrade from UV exposure and other natural processes and fade, requiring a booster tattoo.

I served as the first human test subject for these tattoos. I created solar freckles on my forearm invisible spots that turned blue under UV exposure and reminded me when to wear sunscreen. My lab is also working on invisible UV-protective tattoos that would absorb UV light penetrating through the skin, like a long-lasting sunscreen just below the surface. Were also working on thermometer tattoos using temperature-sensitive inks. Ultimately, we believe tattoo inks could be used to prevent and diagnose disease.

Temporary high-tech tattoos

Temporary transfer tattoos are also undergoing a high-tech revolution. Wearable electronic tattoos that can sense electrophysiological signals like heart rate and brain activity or monitor hydration and glucose levels from sweat are under development. They can even be used for controlling mobile devices, for example shuffling a music playlist at the touch of a tattoo, or for luminescent body art that lights up the skin.

The advantage of these wearable tattoos is that they can use battery-powered electronics. The disadvantage is that they are much less permanent and comfortable than traditional tattoos. Likewise, electronic devices that go underneath the skin are being developed by scientists, designers and biohackers alike, but they require invasive surgical procedures for implantation.

Tattoos injected into the skin offer the best of both worlds: minimally invasive, yet permanent and comfortable. New needle-free tattooing methods that fire microscopic ink droplets into the skin are now in development. Once perfected they will make tattooing quicker and less painful.

Ready for everyday use?

The color-changing tattoos in development are also going to open the door to a new kind of dynamic body art. Now that tattoo colors can be changed by an electromagnetic signal, youll soon be able to program your tattoos design, or switch it on and off. You can proudly display your neck tattoo at the motorcycle rally and still have clear skin in the courtroom.

As researchers develop dynamic tattoos, theyll need to study the safety of the high-tech inks. As it is, little is known about the safety of the more than 100 different pigments used in normal tattoo inks. The U.S. Food and Drug Administration has not exercised regulatory authority over tattoo pigments, citing other competing public health priorities and a lack of evidence of safety problems with the pigments. So U.S. manufacturers can put whatever they want in tattoo inks and sell them without FDA approval.

So far, there is no evidence that tattoos cause cancer, and one study even found that black tattoos protect against UV-induced skin cancer. Still, many tattoo inks contain or degrade into substances that are known to be hazardous, and health complications including infection, allergy and granuloma have been found in about 2% of tattoos. More research is needed to understand the long-term effects of nano- and microimplants in the skin in general.

A wave of high-tech tattoos is slowly upwelling, and it will probably keep rising for the foreseeable future. When it arrives, you can decide to surf or watch from the beach. If you do climb on board, youll be able to check your body temperature or UV exposure by simply glancing at one of your tattoos.

This article is republished from The Conversation under a Creative Commons license. Read the original article here: https://theconversation.com/dynamic-tattoos-promise-to-warn-wearers-of-health-threats-133040.

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What are the Effects of Nanoplastics and Microplastics on our Environment? – AZoCleantech

§ September 22nd, 2020 § Filed under Nanotechnology Journal Comments Off on What are the Effects of Nanoplastics and Microplastics on our Environment? – AZoCleantech

Image credit: Larina Marina/Shutterstock.com

It is very difficult to remain unconcerned about plastic pollution after visualizing images of landfills or sea beaches covered with plastic bags, bottles, and other commonly used plastic materials. The harmful effects of minute plastic fragments, such as microplastics and nanoplastics, on marine creatures, terrestrial plants, birds, and human beings have become a much-discussed topic of the present day. This article discusses the harmful effects of both microplastics and nanoplastics, and the measures/technology adopted to tackle the problem.

Scientists have reported that the real potential hazards of plastics are in their fragmented forms (microand nanoplastics). These minute plastic fragments are the result of the degeneration of large plastic materials. Plastic fragments smaller than a few millimeters in size are commonly known as microplastics. However, in the past couple of years, scientists have started using the term nanoplastics to describe the plastic particlesless than a few micrometers in size. Generally, microplastics are plastic fragments of 0.1 m5 mm in size, whereas, the dimension of nanoplastics is 0.0010.1 m. These fragments are so minute that they are not visible to the naked eye or even under a simple optical microscope.

Mostly in the case of microplastics, one of the main potential risks is it being stuck in the guts of living organisms. However, for nanoplastics, it can easily penetrate the tissues and organs of an organism. In a recent study, nanoplastics have been reported to be present in the tissues of terrestrial plants, harming the ecosystem.

Scientists face immense difficulties in the study of nanoplastics, especially with regard to their occurrence and behavior. Denise Mitrano, Assistant Professor at ETH Zurich, and her colleagues have recently published their findings on monitoring the fate of nanoplastics in Nature Nanotechnology. In their study, the synthesized plastic nanoparticles consist of a metallic core which could be easily traced with commonly available analytical techniques used for metals analysis. Even though their research does not minimizethe effects of plastic pollution, the possibility of the synthesis of metal-doped nanoplastics has very much opened the doors for accurate assessment (in laboratory conditions) of the extent to which nanoplastics pose a threat to our environment.

The harmful effects of microplastics and nanoplastics are mainly mechanical and/or toxicological in nature. When plastic pieces undergo leaching, they release chemicals that are carcinogenic in nature. Some of the chemicals produced after leaching, such as monomers, polymer-associated chemicals, and plastic additives adversely affect the endocrine system.

A team of researchers led by the IAEA has recently published a comprehensive review in the Journal of Environmental Science and Technology in 2020, discussing how often fishes consume tiny plastic particles (resin pellets used in plastics manufacturing) and its aftermath. The study revealed that the biological functions of these fishes that include their metabolism, neurological behavior, intestinal microbiome diversity, and intestinal permeability are greatly affected.

Marc Metian, a Research Scientist at the Radioecology Laboratory of the International Atomic Energy Agency (IAEA) and one of the co-authors of the above-mentioned study, remarked that accurate monitoring is highly essential for understanding the effect of these tiny plastic particles on various organisms. This is primary to design an effective model for environmental management and to develop mitigation strategies.

Some of the strategies include the determination of impacts at the cellular level that would ultimately affect the ecosystem. Scientists believe that formulation of novel degradable plastics that would not have any footprint in our environment would be a necessary step to resolve the problem of plastic pollution.

Read more: Tackling the Great Pacific Garbage Patch with The Ocean Cleanup Project

Since the researchers discovered the adverse effects of microplastics and nanoplastics on the health and environment, they have become more focused on understanding the impacts of these materials and in providing possible solutions in reducing or eliminating these potential environmental threats. Some of the processes and technology used to decrease or eliminate microplastic and nanoplastics pollution are discussed below.

Treatments of wastewater and drinking water are found to be highly effective in the removal of microplastics. This technology showed a reduction of 90% of microplastics. Another measure to bring about a reduction in plastic pollution entails minimal usage of single-use plastic materials, for example, plastic bottles, plastic bags, fork, straws, and cups. Therefore, minor changes in lifestyle could bring about a great change in the environment.

Scientists believe that one of the potential options for reduction or elimination of plastic pollution is the use of microorganisms, such as marine fungus Zalerion maritimum and several bacteria. However, they showed maximum effectiveness in the degradation of microplastics. Similarly, it has been reported that PET polyester plastics undergo enzymatic degradation in a rapid and efficient manner.

The effect of filtration depends on the size distribution of the micro and nanoplastic particles. As expected, the process of removal of microplastics and nanoplastics through filtration is more effective with a decrease in the pore size.

The effect of centrifugation in the removal of microplastics and nanoplastics showed that the percentage removal increased significantly at centrifugation speed between 5000 and 7000 rpm with a gradual increase in time.

This process is typically used in the drinking water treatment for the removal of fine contaminants. It is also found to be effective in wastewater treatments. Recently, researchers found that this technology can be effectively used for the removal of microplastics and nanoplastics.

Microplastics and nanoplastics pollution have become a much more difficult problem to tackle owing to their size. Not only is there a need for a new effective technology for easy removal and elimination of the tiny plastic particles, but there is also a need to educate people about the problems related to the unmindful littering or unnecessary overuse of plastics.

Orayeva, J. (2020) New Research on the Possible Effects of Micro- and Nano-Plastics on Marine Animals. [Online] Iaea. Available at:https://www.iaea.org/newscenter/news/new-research-on-the-possible-effects-of-micro-and-nano-plastics-on-marine-animals(Accessed on 21 September 2020).

Murray, A., and rmeci, B. (2020) Removal Effectiveness of Nanoplastics (<400 nm) with Separation Processes Used for Water and Wastewater Treatment. Water. 12, 635;https://doi.org/10.3390/w12030635

Nature Nanotechnology. Nanoplastic should be better understood.14,299 (2019). https://doi.org/10.1038/s41565-019-0437-7

Hargerbaeumer, A., et al. (2019)Impacts of Micro- and Nano-Sized Plastic Particles on Benthic Invertebrates: A Literature Review and Gap Analysis. Frontiers in Environmental Science. 7, 17.https://doi.org/10.3389/fenvs.2019.00017

Mitrano, D.M.,et al.(2019). Synthesis of metal-doped nanoplastics and their utility to investigate fate and behaviour in complex environmental systems.Nature Nanotechnology.14,362368.https://doi.org/10.1038/s41565-018-0360-

Disclaimer: The views expressed here are those of the author expressed in their private capacity and do not necessarily represent the views of AZoM.com Limited T/A AZoNetwork the owner and operator of this website. This disclaimer forms part of the Terms and conditions of use of this website.

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The Global Automotive Winter Tire Market is expected to grow by $ 0.09 billion during 2020-2024 progressing at a CAGR of 1% during the forecast period…

§ September 22nd, 2020 § Filed under Nanotechnology Journal Comments Off on The Global Automotive Winter Tire Market is expected to grow by $ 0.09 billion during 2020-2024 progressing at a CAGR of 1% during the forecast period…

New York, Sept. 21, 2020 (GLOBE NEWSWIRE) -- Reportlinker.com announces the release of the report "Global Automotive Winter Tire Market 2020-2024" - https://www.reportlinker.com/p04973871/?utm_source=GNW Our reports on automotive winter tire market provides a holistic analysis, market size and forecast, trends, growth drivers, and challenges, as well as vendor analysis covering around 25 vendors. The report offers an up-to-date analysis regarding the current global market scenario, latest trends and drivers, and the overall market environment. The market is driven by the strong auto sales in cold regions, discounts offered on insurance premium, driving adoption of winter tires, and inclement cold weather and need for proper traction driving adoption of winter tires. In addition, strong auto sales in cold regions is anticipated to boost the growth of the market as well. The automotive winter tire market analysis includes application segment and geographical landscapes

The automotive winter tire market is segmented as below: By Application Passenger cars Commercial vehicles

By Geographic Landscapes EMEA Americas APAC

This study identifies the premature breakage of snow chains may drive adoption of winter tire owing to enhanced reliability and efficiency as one of the prime reasons driving the automotive winter tire market growth during the next few years. Also, adoption of nanotechnology to enhance grip and performance in extreme weather conditions and framing of new standards for special winter commercia will lead to sizable demand in the market.

The analyst presents a detailed picture of the market by the way of study, synthesis, and summation of data from multiple sources by an analysis of key parameters. Our automotive winter tire market covers the following areas: Automotive winter tire market sizing Automotive winter tire market forecast Automotive winter tire market industry analysis

Read the full report: https://www.reportlinker.com/p04973871/?utm_source=GNW

About Reportlinker ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

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CWRU-led research team receives $3 million grant to fight breast cancer with nanotech, immunotherapy – Crain’s Cleveland Business

§ September 17th, 2020 § Filed under Nanotechnology Journal Comments Off on CWRU-led research team receives $3 million grant to fight breast cancer with nanotech, immunotherapy – Crain’s Cleveland Business

A team of scientists led by a researcher at Case Western Reserve University recently received a $3 million grant from the National Cancer Institute (NCI) to support their work combining nanotechnology with immunotherapy to fight deadly metastatic breast cancer.

The novel technique sends nanoparticles into the body to wake up "cold" tumors so they can be located and then neutralized by immune cells, according to a news release.

Immunotherapy uses drugs to help the immune system fight cancer, rather than chemotherapy, which uses drugs to kill cancer cells. Nanotechnology manipulates matter at the nanoscale (dimensions measured by nanometers or one-billionth of a meter) to create structures, devices and systems for medical uses and beyond, according to the release.

Efstathios "Stathis" Karathanasis, an associate professor of biomedical engineering at CWRU, is leading the team, which includes researchers from Cleveland Clinic and Duke University.

The five-year grant supports the team as it continues its research, initially on animal models with an eye toward human trials. Much of the groundwork behind the project has been published in a paper in Cancer Research, the official journal of the American Association for Cancer Research.

"We believe our work shows that this combination of nanotechnology with cancer immunotherapy encompasses an inherent promise to treat the most hard-treat metastatic cancers," Karathanasis said in a provided statement. "Our work has been to design a nanoparticle that triggers an activation of antigen-presenting cells in the tumor. Within a few weeks, the patient can have adapted T cells that recognize and fight the cancer."

Breast cancer, which causes more than 42,000 deaths a year, is the second-leading cause of death from cancer in women in the United States; skin cancer is the first. Also called stage IV cancer, metastatic breast cancer causes the vast majority of those deaths. It is breast cancer that has spread to another part of the body most commonly, the liver, brain, bones or lungs, according to the release.

Metastatic cancer cells are often considered stealth killers, "ticking time bombs that remain dormant until they emerge as incurable tumors," said Karathanasis, an engineer by training who began work on nanotechnology solutions to medical problems about two decades ago.

One of the most difficult aspects of diagnosing and treating metastatic breast cancer is that cells often cannot be found until it's too late for successful treatment, according to the release. Though the science continues to develop and offer hope for cancer patients, immunotherapy is only successful about 20% of the time. When it works, it's "highly effective," Karathanasis said in the release.

"But cancer cells hijack and recruit the local immune cells in tumors making them dysfunctional, unfortunately," Karathanasis said. "If there are no danger signals from the body, the immune system doesn't know there is an enemy."

When a tumor appears in the body, immune cells should recognize it and send out cells to try to kill it, as well as "memorize" it, so they can come back and kill it again in recurrences, Karathanasis said in the release. But tumors adapt and repress immune cells so the immune system can't find it.

Karathanasis has developed a way to get the tumor to notify the body's immune system of its presence, according to the release. The team have engineered a nanoparticle to "trigger the antigen-presenting cells in the tumor to start generating fresh signals," he said.

"We are unlocking the immune system, which has been repressed by the tumor," Karathanasis said. "We regenerate the cycle of immunity."

The research team also includes, according to the release: William Schieman, the Goodman-Blum Professor in Cancer Research at Case Western Reserve School of Medicine; Li Lily Wang, associate staff at Cleveland Clinic Lerner Research Institute; and Christopher Hoimes, of Duke University School of Medicine.

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Once-daily levodopa pill for Parkinson’s touted by developer – Clinical Daily News – McKnight’s Long Term Care News

§ September 17th, 2020 § Filed under Nanotechnology Journal Comments Off on Once-daily levodopa pill for Parkinson’s touted by developer – Clinical Daily News – McKnight’s Long Term Care News

Prof. Joachim Loo (left) and LiberaTx CEO Dr. Shashi Kesavapany holding engineered pill samples. Photo credit: NTU Singapore

Drug developers from Singapore are set to test a levodopa pill designed to be taken once daily, potentially resolving the problem of symptom flares between doses in patients with Parkinsons disease.

Levodopa commonly is prescribed to treat tremors, stiffness and slowness of movement in Parkinsons. Multiple oral doses may be needed each day and at set times to keep drug levels steady. The new pills microcapsule is designed to float in the stomach, slowly and continuously delivering levodopa into the upper intestine throughout the day for improved absorption, said Joachim Loo, Ph.D., from Nanyang Technological University.

This is key in maintaining the drugs concentration in the blood, so that dopamine levels in the brain are kept constant over prolonged periods rather than fluctuating, which is the case for current tablets, Loo explained.

The developers have created a start-up company, LiberaTx, to commercialize the microcapsule and are planning clinical trials in Singapore to test its efficacy.

We hope that by reducing dosage to just once a day would greatly improve patient compliance, lower the pill burden of these patients, while alleviating the off periods that these patients experience, Loo said.

An early study using multiple Parkinsons drugs was published in Small, a weekly peer-reviewed scientific journal covering nanotechnology.

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Lab Certified for Antiviral and Antibacterial Efficacy, the AM99 Mask Protects Wearers Against Virus Spread and Touching Contaminated Surfaces – Press…

§ September 17th, 2020 § Filed under Nanotechnology Journal Comments Off on Lab Certified for Antiviral and Antibacterial Efficacy, the AM99 Mask Protects Wearers Against Virus Spread and Touching Contaminated Surfaces – Press…

Dr. Terry T.-L. Au Yeung, the creator behind the mask, trusts the effective mask proven for protection in day-to-day life

SAN FRANCISCO - September 17, 2020 - (Newswire.com)

Digital app pioneer MindBeauty, an industry leader in health technology, has released its AM99 mask which is certified against the coronavirus family of viruses and 17 other types of microorganisms. Its proprietary nanotechnology neutralizes COVID-19 on contact, offering a higher level of protection than other masks on the market. For this reason, Dr. Terry T.-L Au Yeung, Ph.D., chief technology officer of AM99, trusts his own well-being to the mask.

Dr. Au Yeung has made a name for himself as a scientist at the forefront of the industry, with a Ph.D. degree in chemistry and a B.Sc. degree. Additionally, he served as an honorary fellow for eight years. Dr. Au Yeungs accomplishments include authoring over 30 academic publications and refereeing for many international journals.

We developed the AM99 line of masks to meet the urgent need for effective cloth masks, using a patented cloth-like textile that is sustainable and economic, that are designed to safeguard the public. Our masks offer robust protection against the virus to the general public while conserving N95 respirator masks for medical personnel and other frontline responders, Au Yeung says.

Since the majority of Americans are dealing with daily mask wearing for the first time, it can be difficult for consumers to discern fact from fiction regarding general mask effectiveness and practices. There are many products on the market that offer protection for those around the wearer, but not the wearer themselves.

AM99 has changed this by producing a mask designed with proprietary nanotechnology that does not just provide a physical barrier, but rather, neutralizes COVID-19-laden respiratory droplets on contact. Research shows 95% viral de-activation efficiency within two hours, decreasing the chances of viral transmission. In this way, AM99 masks safeguard both the wearer and those in their vicinity.

Certified and trusted by an industry-leading doctor and designed with the ability to neutralize COVID-19 on the spot, AM99 masks offer consumers an early-to-market level of protection.

About AM99

MindBeauty created the AM99 line of protective face masks as a response to the heightened need for simple and effective solutions to contain, protect against and minimize the effects of the global outbreak. The result is a reusable face mask that is an effective, safe and fashionable option thats early-to-market for users and outperforms other masks in the market landscape. AM99 face masks leverage proprietary nanotechnology and are lab-certified to protect against the current COVID-19 pandemic and other potentially harmful microorganisms. AM99 masks offer an additional layer of lab-certified protection that actively neutralizes COVID-19 and other potentially harmful microorganisms on contact. Learn more at am99tech.com.

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Original Source: Lab Certified for Antiviral and Antibacterial Efficacy, the AM99 Mask Protects Wearers Against Virus Spread and Touching Contaminated Surfaces

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Kim Dunbar Explains Nanotechnology Applications and Where Its Likely to Lead – Press Release – Digital Journal

§ September 15th, 2020 § Filed under Nanotechnology Journal Comments Off on Kim Dunbar Explains Nanotechnology Applications and Where Its Likely to Lead – Press Release – Digital Journal

Kim Renee Dunbar Elaborates on Nanotechnology Applications and Where They Might lead

COLLEGE STATION, TX / ACCESSWIRE / September 15, 2020 / Kim Dunbar is a Distinguished Professor of Chemistry at Texas A & M University. She's won numerous awards for her work in inorganic chemistry. She currently focuses on coordination chemistry, which opens up many avenues to explore. She is one of the researchers leading the way in nanotechnology. She states that nanotech is currently used in various applications, which is expected to increase.

What is Nanotech?

Nanotech involves controlling matter at the molecular level. Kim Dunbar explains this gives scientists options that were once the stuff of science fiction. Nanotech spans all scientific disciplines, including chemistry, engineering, and materials science. Nanoparticles are measured in nanometers. There are 25,400,000 nanometers in an inch.

Kim Dunbar Explains Nanotech Today

Kim Dunbar states that nanotechnology is now commonly used in the medical field. Nano drugs are one exciting application. Nanotechnology allows drugs to be delivered to highly targeted areas. This can lead to more effective treatments with fewer side effects than traditional therapies. Nanoscience ts also targeted at increasing computing power and memory in electronic devices while scaling down the size. Nanotechnology has usage in batteries and solar power cells. It is also being used in surprising applications in food. According to Kim Renee Dunbar, clay nanoparticles are being used to prevent gases from entering food packaging.

The Future of Nanotech

When it comes to the future of nanotech, Kim Renee Dunbar says there are sure to be surprises. One interesting application is sensors for food. It is hypothesized that carbon nanotubes could be placed on food packaging to detect food spoilage. Nanosensors will also be able to detect bacteria in food packaging plants themselves. This could provide safety testing at a much quicker and cost-effective rate than lab testing.

Kim Dunbar says there are many medical applications on the horizon as well. One of these is nanotech sensors that are injected into the body. This would allow doctors to monitor the patient or check for conditions in a less invasive way. There is an almost endless amount of possibilities for uses of these "electroceuticals."

Self-healing materials are another concept Kim Renee Dunbar finds fascinating. Nanoparticles could go where they were needed in the material to fill in cracks or worn areas. They could also be used as sensors to detect structural damage to bridges and nuclear power plants before the potential damage can pose a danger.

While these applications may sound like science fiction, Kim Renee Dunbar says they are closer than you think. It's hard to imagine the changes that nanotechnology will eventually bring about as research continues, but it's a safe bet that the world will benefit from these emerging technologies.

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SOURCE: Kim Dunbar

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Rio2 Limited and Sixth Wave Innovations Inc. Sign Letter of Intent for IXOS Mining Technology Trials – Press Release – Digital Journal

§ September 15th, 2020 § Filed under Nanotechnology Journal Comments Off on Rio2 Limited and Sixth Wave Innovations Inc. Sign Letter of Intent for IXOS Mining Technology Trials – Press Release – Digital Journal

NOT FOR DISTRIBUTION IN THE U.S. OR OVER U.S. NEWSWIRES

HALIFAX, Nova Scotia and VANCOUVER, British Columbia, Sept. 15, 2020 (GLOBE NEWSWIRE) -- Sixth Wave Innovations Inc. (CSE:SIXW) (OTCQB:ATURF) (FSE:AHUH) (Sixth Wave) and Rio2 Limited (Rio2) (TSXV:RIO) (OTCQX:RIOFF) (BVL:RIO) are pleased to announce that they have executed a non-binding Letter of Intent (LOI) for the trialing of Sixth Waves patented IXOS purification polymer (the IXOS Mining Technology) for Rio2s Fenix Gold Project in Chile.

Under the terms of the LOI, Rio2 will send representative ore samples from its Fenix Gold Project to Sixth Wave for testing and analysis in its Salt Lake City facility. Sixth Wave will perform a combination of leaching and recovery tests using its IXOS Mining Technology on these samples consistent with protocols for the expected heap leach mining activity planned for the Fenix Gold Project. Upon completion of the testing, to be performed in October of this year, and pending positive results, the two companies will work to negotiate a definitive agreement to proceed to a complete on-site pilot Adsorption/Desorption/Recovery (ADR) plant scaled to operate on a 400t pilot leach pad.

The objective of this work, from Rio2s perspective, is to determine whether Sixth Waves IXOS Mining Technology can be successfully applied to enhance the extraction of gold from Fenix Gold ore by using molecularly imprinted polymers rather than traditional carbon for the gold adsorption process. If successful, the application of the IXOS Mining Technology is expected to result in a reduction of capex and opex related to the gold extraction process.

Upon successful completion and positive results of the pilot program, the companies would then move to an implementation phase incorporating the IXOS Mining Technology in the actual processing plant to be constructed at the Fenix Gold Project.

We are very excited about this project and working with Rio2. The IXOS process should excel in comparison to traditional activated carbon because of the high rejection of base metal and scaling and the smaller process plant required for IXOS. Substantially lower power consumption in the desorption and recovery stages and no need for regeneration will also play a large role in reduced opex, noted Dr. Jon Gluckman, President and CEO of Sixth Wave Innovations Inc. He went on to say, It is exciting to be involved with Rio2 at this phase of the Fenix Gold Project as it allows us the ability to optimize the design of the ADR circuit without having to worry about retrofit constraints.

Rio2 is always looking to embrace and trial new technology with the objective of bringing enhanced value to our stakeholders through the reduced capex/opex opportunities that innovative technologies can bring. The Fenix Gold Project is currently the largest undeveloped gold heap leach project in the Americas and we look forward to working alongside Sixth Wave during the development phase of the project, stated Mr. Alex Black, President and CEO of Rio2 Limited.

About RIO2 Limited

Rio2 is a mining company with a focus on development and mining operations with a team that has proven technical skills as well as a successful capital markets track record. Rio2 is focused on taking its Fenix Gold Project in Chile to production in the shortest possible timeframe based on a staged development strategy. In addition to the Fenix Gold Project in development in Chile, Rio2 Limited continues to pursue additional strategic acquisitions where it can deploy its operational excellence and responsible mining practices to build a multi-asset, multi-jurisdiction, precious metals company focused in the Americas.

To learn more about Rio2 Limited, please visit: http://www.rio2.com or Rio2's SEDAR profile at http://www.sedar.com.

ON BEHALF OF THE BOARD OF RIO2 LIMITED

Alex Black President, CEO & Director Email: info@rio2.com Tel: 1 (604) 260-2696

About Sixth Wave

Sixth Wave is a development stage nanotechnology company with patented technologies that focus on extraction, purification, and detection of target substances at the molecular level using highly specialized Molecularly Imprinted Polymers (MIPs).The Company is in the process of commercializing its, IXOS, a line of extraction polymers for the gold mining industry.

Sixth Wave can design, develop and commercialize MIP solutions across a broad spectrum of industries. The company is focused on nanotechnology architectures that are highly relevant for detection, purification, and separation of viruses, biogenic amines and other pathogens, and nutraceuticals for which the Company has products at various stages of development.

For more information about Sixth Wave, please visit our web site at: http://www.sixthwave.com

ON BEHALF OF THE BOARD OF DIRECTORS

Jon Gluckman Jonathan Gluckman, Ph.D., President & CEO

For information, please contact the Company: Phone: (801) 582-0559 E-mail: info@sixthwave.com

Forward-Looking Statements

This press release contains forward-looking statements and forward-looking information (collectively forward-looking information) within the meaning of applicable securities laws, including statements regarding Rio2s planned development of its Fenix Gold Project, other aspects of Rio2s anticipated future operations and plans, and the testing and performance of Sixth Waves IXOS Mining Technology.

All statements included herein, other than statements of historical fact, may be forward-looking information and such information involves various risks and uncertainties. Forward-looking information is often, but not always, identified by the use of words such as seek, anticipate, plan, continue, estimate, expect, may, will, project, predict, potential, targeting, intend, could, might, should, believe, and similar expressions. The forward-looking information is based on certain key expectations and assumptions made by management of Rio2 and Sixth Wave, including but not limited to: expectations concerning prevailing commodity prices, exchange rates, interest rates, applicable royalty rates and tax laws; capital efficiencies; legislative and regulatory environment of Chile; future production rates and estimates of capital and operating costs; estimates of reserves and resources; anticipated timing and results of capital expenditures; the sufficiency of capital expenditures in carrying out planned activities; performance; the availability and cost of financing, labor and services; and Rio2s ability to access capital on satisfactory terms.

Rio2 and Sixth Wave believe the expectations reflected in these forward-looking statements are reasonable, but no assurance can be given that these expectations will prove to be correct and such forward-looking statements in this press release should not be unduly relied upon. A description of assumptions used to develop such forward-looking information and a description of risk factors that may cause actual results to differ materially from forward-looking information can be found in disclosure documents of both Rio2 and Sixth Wave on the SEDAR website at http://www.sedar.com or the websites of Rio2 (www.rio2.com) and Sixth Wave (www.sixthwave.com), respectively. In particular, successful commercial deployment of the IXOS technology is subject the risk that the technology may not prove to be successful in achieving sufficient environmental or production efficiencies, uncertainty of timing or availability of required regulatory approvals, lack of track record of developing products for mining applications and the need for additional capital to carry out product development activities. Forward-looking statements included in this press release are made as of the date of this press release and such information should not be relied upon as representing its views as of any date subsequent to the date of this press release. Rio2 and Sixth Wave have attempted to identify important factors that could cause actual results, performance or achievements to vary from those current expectations or estimates expressed or implied by the forward-looking information. However, there may be other factors that cause results, performance or achievements not to be as expected or estimated and that could cause actual results, performance or achievements to differ materially from current expectations. Rio2 and Sixth Wave disclaim any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as expressly required by applicable securities legislation.

This press release does not constitute an offer to sell or a solicitation of an offer to buy any of the securities in the United States. The securities have not been and will not be registered under the United States Securities Act of 1933, as amended (the U.S. Securities Act) or any state securities laws and may not be offered or sold within the United States or to U.S. Persons unless registered under the U.S. Securities Act and applicable state securities laws or an exemption from such registration is available. Not for distribution to U.S. Newswire Services or for dissemination in the United States. Any failure to comply with this restriction may constitute a violation of U.S. Securities laws.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts the responsibility for the adequacy or accuracy of this release.

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MindBeauty’s AM99 is the Next Generation of Reusable Face Masks, Neutralizing COVID-19 Upon Contact – Press Release – Digital Journal

§ September 11th, 2020 § Filed under Nanotechnology Journal Comments Off on MindBeauty’s AM99 is the Next Generation of Reusable Face Masks, Neutralizing COVID-19 Upon Contact – Press Release – Digital Journal

SAN FRANCISCO, CA / ACCESSWIRE / September 10, 2020 / MindBeauty has announced the launch of its AM99 mask, founded as a direct response to the current global pandemic. Utilizing patented nanotechnology proprietary to MindBeauty, the cotton-based mask deactivates coronavirus and other families of viruses on contact; the mask's effectiveness in shielding against spray and splashback is key in helping to decrease viral transmission. It is also cost-effective, sustainable, reusable and hand-washable.

"It was important for us to develop a next-generation mask that protects against all kinds of viruses, not only coronavirus," says Joei Lau, Founder of AM99. "The AM99 mask is cost-effective, sustainable, hand-washable, and customizable. It not only protects its wearer but actively decreases chances of transmission by neutralizing pathogens on contact, with our research showing up to 95% viral de-activation efficiency."

The AM99 mask helps satisfy the need for simple, effective solutions to promote public health around the world. According to the AM99 Whitepaper, "AM99 products are manufactured using patented Japanese nanotechnology to ensure a strong and prolonged antiviral and antibacterial effect against the family of coronaviruses and at least 17 other potentially harmful microbes."

AM99 masks are also customizable, capable of providing businesses or other organizations the highest level of protection tailored to suit specific requirements, from corporate branding, team or faculty branding, or color-coded risk identification, there are a wide array of customizable options to suit any organization's needs.

Discover why the technology behind the AM99 mask makes it a highly effective form of protection against the virus.

About AM99

MindBeauty created the AM99 line of protective face masks as a response to the heightened need for simple and effective solutions to contain, protect against and minimize the effects of the global outbreak. The result is a reusable face-mask is an effective, safe and fashionable option that's early-to-market for users and outperforms other masks in the market landscape. AM99 face masks leverage proprietary nanotechnology and are lab-certified to protect against the current COVID-19 pandemic and other potentially harmful microorganisms. AM99 masks offer an additional layer of lab-certified protection that actively neutralizes COVID-19 and other potentially harmful microorganisms on contact. Learn more at am99tech.com.

CONTACT INFORMATION: Tiffany Kayar tiffanyPR@newswiremail.com

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Iran among world’s top clusters of science and technology – Tehran Times

§ September 9th, 2020 § Filed under Nanotechnology Journal Comments Off on Iran among world’s top clusters of science and technology – Tehran Times

TEHRAN Iran ranked 43rd among 100 most vibrant clusters of science and technology (S&T) worldwide for the third consecutive years, according to the Global Innovation Index (GII) 2020 report.

Every year, the Global Innovation Index ranks the innovation performance of more than 130 economies around the world. The GII 2020 with a theme of Who Will Finance Innovation? discusses how the state of innovation finance is changing rapidly. This chapter reveals and analyzes the annual GII innovation rankingsby top-performing economies, regions, and innovation components.

The total ranking of Iran is 67 in the GII 2020 report, which was 61 in 2019.

The top 100 clusters are located in 26 countries, 6 of which including Brazil, China, India, Iran, Turkey, and Russia represent middle-income economies. While, the U.S. continues to host the largest number of clusters (25), followed by China (17), Germany (10), and Japan (5).

Iran also experienced a three-level improvement compared to 2019.

Tehran also ranked 9th among top regions (clusters) of science and technology in middle-income countries, surpassing Berlin, Zurich, Bangalore, Delhi, Lausanne, Vienna, Istanbul, Sao Paulo, Ankara, and Mumbai.

In 2020, Tokyo-Yokohama is the top-performing cluster again due to the excellent performance of this region in patent registration.

The ranking published by the WIPO, which is the global forum for intellectual property services, policy, information, and cooperation. It is a self-funding agency of the United Nations, with 191 member states.

It aims to lead the development of a balanced and effective international intellectual property system that enables innovation and creativity for the benefit of all.

Iranian scientific journals among highly cited worldwide

Journal of Nanostructure in Chemistry (JNSC) affiliated to Islamic Azad University was ranked forty-fifth among 103 top nanotechnology journals in Journal Citation Reports 2020 published by Clarivate Analytics.

Some 12 specialized journals in the field of nanotechnology are published in English in the country.

The JCR 2019 ranking report includes 42 journals from Iran, including the Journal of Nanostructure in Chemistry with an impact factor of 4.077.

Iranian scientific journals such as the Journal of Nanostructures (affiliated to Kashan University), Nanomedicine Journal (Mashhad University of Medical Sciences), Journal of Nanoanalysis (Tehran University of Medical Sciences) were listed in the ESCI index of WOS database.

Moreover, the Journal of Water and Environmental Nanotechnology, Nanomedicine Research Journal, and International Nanoscience and Nanotechnology were also listed in the Scopus Index.

FB/MG

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Navigating the Cannabis Industry in the Current Climate – Cannabis Industry Journal

§ September 9th, 2020 § Filed under Nanotechnology Journal Comments Off on Navigating the Cannabis Industry in the Current Climate – Cannabis Industry Journal

All major industries took a hit during the COVID-19 pandemic, but in many states, cannabis dispensaries were labeled as essential, which has allowed the industry to continue with some alterations. The impact now will come from what innovations and improvements the industry can leverage going forward.

From changes to protocols and buyer behaviors to supply chain disruptions, there were many new hurdles for the industry in addition to the ones cannabis businesses already faced, such as funding. But the silver lining could be that businesses within the cannabis industry become less of a specialty and more every day than ever before.

Overall, the industry has fared well, in part thanks to its distinction as an essential service in states where cannabis is legal. Its possible states made this decision for the same reason that alcohol businesses were deemed essential in most places: hospitals are not equipped during pandemic times to take care of people who are being forced to detox or those suffering from anxiety because they dont have access to their legal drug of choice.

In a multitude of ways, cannabis businesses have adapted to bring calm in a storm while at the same time making manufacturing adjustments to meet the CDC guidelines. For example, there is more attention placed on individually pre-packaged products for single use; something that is less sharable as an experience but eminently practical.

Another area that has shifted a little is in the limiting of the exchange and interaction between business owners and staff relative to the customers. Its all in the aim of mitigating the risk of exposure, but it has changed the dynamic in many cannabis businesses. This is the new normal for the time being and the industry has adapted well.

Ultimately, retail cannabis businesses today are no different than the retail of candy, cigarettes or alcohol. Certainly, segments of the industry have still struggled. Lack of tourism and the curbside/take out circumstances at dispensaries took their toll. But without the opportunity to still conduct business in some capacity, 50-60% of all operators would have gone out of business. Plus, as many people use cannabis to offset medical symptoms, including pain management, there is a legitimate need for cannabis to be available. The pandemic has provided the opportunity for many who might not have tried it before to give it a chance to help them medicinally.

Driven by consumer interests, many dispensaries have adapted to provide curbside pickup options, delivery of online orders and more. That has meant that the customer also needs to be more knowledgeable about cannabis: the experienced consumer knows what they like and want and can make their choices at a distance. Someone who is new to cannabis use might find navigating the choices and options a little more difficult, without the help of experienced staff. The breadth of material online and the ability of some dispensaries to share content that helps the consumer to make choices, in the absence of walking around the dispensary, have been additional tools at the disposal of businesses.

That said, the cannabis industry today is not a vastly different one: it is adapting to the new rules and new reality. Whether this way of doing businessat a distanceis a temporary or permanent solution will be dependent upon what federal and state regulators dictate in the months ahead, but there is likely to be ongoing demand for being able to order online and keep social distance protocols in place.

An interesting example is the Ontario Cannabis Store (OCS) in Ontario, Canada. This is a government run shop that has retail as well as a robust online presence, with free delivery during the pandemic. This has facilitated an increase in new customers, which had already jumped, post legalization. People who might have felt uncomfortable going into a dispensary can still learn about cannabis online and order it, from the relative comfort and safety of their sofa.

The industry has long been focused on overseas suppliers. With the arrival of the pandemic and restrictions on obtaining products from other countries, supply chains have been disrupted for many cannabis businesses. That has forced many to shift their supply chains to more local manufacturers, in North and South America.

In the long run, this should have a positive impact for the industry, so that despite the short-term disruption to the supply chain, which is having an impact on the industry as a whole, there could be an upside for local producers, growers and manufacturers. It will take time to know how this will all play out.

For a new cannabis startup in these times, the key will be what it has always been for any business, just to a greater degree: due diligence. Companies that want to open a cannabis business, whether during the pandemic or not, need to evaluate the opportunity as one would any investment. Its all about the numbers: data for the industry as a whole and specifically from competition. These days, that data is widely available and more and more consultants and investors have expertise in this industry.Overall, there is more interest in the industry than ever before

Its vital to be extremely well versed, particularly for businesses that are relatively new in the industry, because the single biggest issue for many has and will continue to be funding and investment. The cannabis industry is no different than any other business, except for the fact that it is a specialty business. With that comes the need to look for funding among investors who have some knowledge or appreciation for the industry.

Some of the key concerns traditional investors will have include:

So, while traditional banking institutions will often deal with the proceeds from the cannabis industry, including allowing bank accounts for these businesses, there is far less of a chance that they would invest in a cannabis business, for fear of risking their license. They can even go so far as to refuse to include income from a cannabis business in the determination of a loan application.

There are more unique lending or investing groups that either specialize in cannabis or are starting to open their books to specialize in cannabis.Overall, there is more interest in the industry than ever before, as it becomes normalized in American society: more participants and more insiders of the industries that are willing to invest in the right idea.

The fact that cannabis businesses and dispensaries have been deemed essential services during the pandemic, where they legally operate, has shed new light on the relevance of these businesses and the advantages of more widespread legalization.Consumers will help drive the innovations as they demand clean consumption methods

In fact, the pandemic has normalized a lot of new behaviors, including the acceptable use of cannabis to help with stress and anxiety. People are, perhaps thanks to staying at home more, doing the legwork to understand how cannabis could be useful to them in managing their stress. Themedicinal benefits of cannabis have long been researched and understood: consumers are coming into the fray to express their interest in it, which can only fuel the possibility of more widespread legalization.

Add to this the fact that the cannabis industry is a growth industry. There are companies and jobs that arent coming back, post-pandemic. There is an opportunity to grow the cannabis industry to the general benefit of many, both as business owners and employees. The revenue generated from taxation following legalization would also benefit many state coffers. Federal level legalization would be the panacea to eliminate the mixed message, state by state regulation that currently exists.

As more and more people become interested in the industry, and as cannabis use is normalized within society through legalization, the opportunities for the industry can only expand.

For an industry that started on the simple concept of smoking cannabis, the advances have already been legion: edibles, nanotechnology-based formulations for effective, clean consumption and many more innovations.

In a world that increasingly sees smoking as a negative, for the obvious impact to lung health, there are so many opportunities to grow the industry to find consumption methods that are safe and still deliver the impact of the inhaled version.

Here again, consumers will help drive the innovations as they demand clean consumption methods. The technology is available to make this possible; it only takes innovation and education to find the best ways to move this industry forward.

As legalization expandsand particularly if it is dealt with at the federal levelthe industry will be able to capitalize on existing infrastructure for manufacturing and distribution, allowing new businesses to grow, get funded and thrive in the new normal.

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Nanomedicine Market Projected to Be Resilient During 2017-2023 – Kentucky Journal 24

§ August 26th, 2020 § Filed under Nanotechnology Journal Comments Off on Nanomedicine Market Projected to Be Resilient During 2017-2023 – Kentucky Journal 24

Overview:

Nanomedicine is an offshoot of nanotechnology, and refers to highly-specific medical intervention at the molecular scale for curing diseases or repairing damaged tissues. Nanomedicine uses nano-sized tools for the diagnosis, prevention and treatment of disease, and to gain increased understanding of the complex underlying pathophysiology of the disease. It involves three nanotechnology areas of diagnosis, imaging agents, and drug delivery with nanoparticles in the 11,000 nm range, biochips, and polymer therapeutics.

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Majority of nanomedicines prescribedcurrently, allow oral drug delivery and its demand is increasing significantly. Although these nanovectors are designed to translocate across the gastrointestinal tract, lung, and bloodbrain barrier, the amount of drug transferred to the organ is lower than 1%; therefore improvements are challenging. Nanomedicines are designed to maximize the benefit/risk ratio, and their toxicity must be evaluated not only by sufficiently long term in vitro and in vivo studies, but also pass multiple clinical studies.

Market Analysis:

The Global Nanomedicine Market is estimated to witness a CAGR of 17.1% during the forecast period 20172023. The nanomedicine market is analyzed based on two segments therapeutic applications and regions.

The major drivers of the nanomedicine market include its application in various therapeutic areas, increasing R&D studies about nanorobots in this segment, and significant investments in clinical trials by the government as well as private sector. The Oncology segment is the major therapeutic area for nanomedicine application, which comprised more than 35% of the total market share in 2016. A major focus in this segment is expected to drive the growth of the nanomedicine market in the future.

Regional Analysis:

The regions covered in the report are the Americas, Europe, Asia Pacific, and Rest of the World (ROW). The Americas is set to be the leading region for the nanomedicine market growth followed by Europe. The Asia Pacific and ROW are set to be the emerging regions. Japan is set to be the most attractive destination and in Africa, the popularity and the usage of various nano-drugs are expected to increase in the coming years. The major countries covered in this report are the US, Germany, Japan, and Others.

Therapeutic Application Analysis:

Nanomedicines are used as fluorescent markers for diagnostic and screening purposes. Moreover, nanomedicines are introducing new therapeutic opportunities for a large number of agents that cannot be used effectively as conventional oral formulations due to poor bioavailability. The therapeutic areas for nanomedicine application are Oncology, Cardiovascular, Neurology, Anti-inflammatory, Anti-infectives, and various other areas. Globally, the industry players are focusing significantly on R&D to gain approval for various clinical trials for future nano-drugs to be commercially available in the market. The FDA should be relatively prepared for some of the earliest and most basic applications of nanomedicine in areas such as gene therapy and tissue engineering. The more advanced applications of nanomedicine will pose unique challenges in terms of classification and maintenance of scientific expertise.

Key Players:

Merck & Co. Inc., Hoffmann-La Roche Ltd., Gilead Sciences Inc., Novartis AG, Amgen Inc., Pfizer Inc., Eli Lilly and Company, Sanofi, Nanobiotix SA, UCB SA and other predominate & niche players.

Competitive Analysis:

At present, the nanomedicine market is at a nascent stage but, a lot of new players are entering the market as it holds huge business opportunities. Especially, big players along with the collaboration with other SMBs for clinical trials of nanoparticles and compounds are coming with new commercial targeted drugs in the market and they are expecting a double-digit growth in the upcoming years. Significant investments in R&D in this market are expected to increase and collaborations, merger & acquisition activities are expected to continue.

Benefits:

The report provides complete details about the usage and adoption rate of nanomedicines in various therapeutic verticals and regions. With that, key stakeholders can know about the major trends, drivers, investments, vertical players initiatives, government initiatives towards the nanomedicine adoption in the upcoming years along with the details of commercial drugs available in the market. Moreover, the report provides details about the major challenges that are going to impact on the market growth. Additionally, the report gives the complete details about the key business opportunities to key stakeholders to expand their business and capture the revenue in the specific verticals to analyze before investing or expanding the business in this market.

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Food Traceability Software Market Overview on Key Innovations 2026 – Kentucky Journal 24

§ August 22nd, 2020 § Filed under Nanotechnology Journal Comments Off on Food Traceability Software Market Overview on Key Innovations 2026 – Kentucky Journal 24

According to Stratistics MRC, the Global Food Traceability Software market is growing at a CAGR of 9.5% during the forecast period. Some of the key factors such as traces fault and assist product evoke, and rising user apprehension for food safety are driving the growth of the market. However, extra price on traceability systems is hampering the growth of the market.

Food traceability software allows user the capability to investigate, track, and store information concerning the form of food products. Numerous food traceability products offer tools for optimizing command expenses and budget, produce allergy warnings, and contacting seller. One of the most regular types is the capability to help users retain health and safety requirements.

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Based on Type, Enterprise Resource Planning system segment is likely to have a huge demand for the food and beverage manufacturing as it offers the essential visibility into food safety, quality control and traceability. Enterprise Resource Planning solution can also offer cost and efficiency profit in areas such as forecasting and scheduling or inventory, logistics, manufacture or waste organization.

By Geography, Asia Pacific region is likely to have a lucrative growth in forecast period owingthe rising R&D funding for expansion of microscopes, growing nanotechnology delve into, low material charge, and increasing capability and university quality in talented Asia Pacific countries such as China and India are the major factors driving the growth of this market.

Some of the key players profiled in the Food Traceability Software Market include IBM Corp., WaudWare Incorporated, Open Systems Inc., Minotaur Software Ltd., MarKov Computer Systems, LINKFRESH Software Limited., International Traceability Systems Limited, Famous Software LLC, Edible Software, and Carlisle Technology.

Product Types Covered: Web Based Cloud Based

Types Covered: Enterprise Resource Planning (ERP) Friction Stir Welding Laboratory Information Management Software (LIMS) Linear Friction Welding Quality Management Software Rotary Friction Welding Warehouse Software Other Types

Applications Covered: Small-to-Medium Enterprise (SMEs) Large Enterprises

End User: Warehouse Service Providers Food Retailers Food Manufacturers Other End Users

Regions Covered: North America o US o Canada o Mexico Europe o Germany o UK o Italy o France o Spain o Rest of Europe Asia Pacific o Japan o China o India o Australia o New Zealand o South Korea o Rest of Asia Pacific South America o Argentina o Brazil o Chile o Rest of South America Middle East & Africa o Saudi Arabia o UAE o Qatar o South Africa o Rest of Middle East & Africa

What our report offers: Market share assessments for the regional and country level segments Market share analysis of the top industry players Strategic recommendations for the new entrants Market forecasts for a minimum of 9 years of all the mentioned segments, sub-segments, and the regional markets Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations) Strategic recommendations in key business segments based on the market estimations Competitive landscaping mapping the key common trends Company profiling with detailed strategies, financials, and recent developments Supply chain trends mapping the latest technological advancements

Free Customization Offerings: All the customers of this report will be entitled to receive one of the following free customization options: Company Profiling o Comprehensive profiling of additional market players (up to 3) o SWOT Analysis of key players (up to 3) Regional Segmentation o Market estimations, Forecasts and CAGR of any prominent country as per the clients interest (Note: Depends of feasibility check) Competitive Benchmarking Benchmarking of key players based on product portfolio, geographical presence, and strategic alliances

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