Cend Therapeutics Announces Acquisition of Impilo Therapeutics – GlobeNewswire

§ September 26th, 2020 § Filed under Nano Medicine Comments Off on Cend Therapeutics Announces Acquisition of Impilo Therapeutics – GlobeNewswire

September 21, 2020 07:00 ET | Source: Cend Therapeutics Inc.

SAN DIEGO, Sept. 21, 2020 (GLOBE NEWSWIRE) -- Cend Therapeutics, Inc., a clinical-stage biotech company, announced today that it has acquired Impilo Therapeutics, Inc. The combination expands Cends drug delivery capabilities to create a unique platform for targeted tissue penetrating delivery of nucleic acid-based medicines to solid tumor cancers.

While antisense and siRNA medicines have reached market for a range of metabolic, neurological and neuro-muscular conditions, none have reached market for anticancer applications. By combining Impilo with Cend our objective is to address delivery issues that have limited the ability of nucleic acid-based medicines to benefit cancer patients, commented David Slack, CEO of Cend.

Cends lead asset, CEND-1, has generated encouraging clinical data showing the ability to enhance delivery of standard-of-care chemotherapy for pancreatic cancer patients, and the Company has generated similarly encouraging preclinical results for a variety of therapeutic modalities, commented Sangeeta Bhatia, MD, PhD, scientific co-founder of Impilo and Director of MITs Center for Cancer Nanomedicine.

With the combination of Cend and Impilo technologies, we have demonstrated unique abilities to deliver antisense, siRNA, microRNA, and immunostimulatory oligonucleotides selectively to solid tumor cancers and certain immune cells, commented Frank Slack, PhD, scientific co-founder of Impilo and Director of Harvards Initiative for RNA Medicine.

The scientific founders of Cend and Impilo have collaborated for many years and generated significant publications, commented Cend Executive Chairman, Erkki Ruoslahti. Cend will continue to work closely with Impilos founders as part of our extended team.

Via acquisition of Impilos assets, the CendR Platform combines Cends clinical-stage targeted tumor penetrating peptide, CEND-1, with additional targeting capabilities. It also brings nanoparticle technologies, including fusogenic nanoparticles that can deliver high payloads of nucleic acid-based drugs directly into the cytosol compartment of cells.

Financial details of the transaction have not been disclosed. Accompanying the acquisition, Sangeeta Bhatia and Frank Slack will join Erkki Ruoslahti, MD, PhD; Tambet Teesalu, PhD; and Kazuki Sugahara, MD on Cends Scientific Advisory Board. Impilo scientific co-founder and Distinguished Professor at UC San Diego, Michael Sailor, PhD will join Cends Board of Directors.

About Cend Therapeutics

Cend is a clinical-stage biotech company focused on a novel approach to enhance and more selectively deliver treatments for solid tumor cancers. Poor penetration of drugs into tumors is a major issue in cancer therapy as it limits access and therefore efficacy of current therapies. The CendR Platform provides a targeted tissue penetration capability to specifically enhance drug delivery to tumors.

For additional information, please visit http://www.cendrx.com or contact us via info@cendrx.com.

La Jolla, California, UNITED STATES


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