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COVID-19 Impact: Temporary Surge in Sales of Methyl Thioglycolate Product Observed amid Panic Buying by Consumers – Cole of Duty

§ May 10th, 2020 § Filed under Nano Medicine Comments Off on COVID-19 Impact: Temporary Surge in Sales of Methyl Thioglycolate Product Observed amid Panic Buying by Consumers – Cole of Duty

The report on the Methyl Thioglycolate market provides a birds eye view of the current proceeding within the Methyl Thioglycolate market. Further, the report also takes into account the impact of the novel COVID-19 pandemic on the Methyl Thioglycolate market and offers a clear assessment of the projected market fluctuations during the forecast period. The different factors that are likely to impact the overall dynamics of the Methyl Thioglycolate market over the forecast period (2019-2029) including the current trends, growth opportunities, restraining factors, and more are discussed in detail in the market study.

The Methyl Thioglycolate market study is a well-researched report encompassing a detailed analysis of this industry with respect to certain parameters such as the product capacity as well as the overall market remuneration. The report enumerates details about production and consumption patterns in the business as well, in addition to the current scenario of the Methyl Thioglycolate market and the trends that will prevail in this industry.

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What pointers are covered in the Methyl Thioglycolate market research study?

The Methyl Thioglycolate market report Elucidated with regards to the regional landscape of the industry:

The geographical reach of the Methyl Thioglycolate market has been meticulously segmented into United States, China, Europe, Japan, Southeast Asia & India, according to the report.

The research enumerates the consumption market share of every region in minute detail, in conjunction with the production market share and revenue.

Also, the report is inclusive of the growth rate that each region is projected to register over the estimated period.

The Methyl Thioglycolate market report Elucidated with regards to the competitive landscape of the industry:

The competitive expanse of this business has been flawlessly categorized into companies such as

Market Segment Analysis The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type 98% 99% Others

Segment by Application Medicine Pesticide Others

Global Methyl Thioglycolate Market: Regional Analysis The report offers in-depth assessment of the growth and other aspects of the Methyl Thioglycolate market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America. The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region. Global Methyl Thioglycolate Market: Competitive Landscape This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019. The major players in the market include Xinyi Taisong Chemical, Suzhou Ausun Fine Chemical, Shaanxi Rebecca Bio-Tech, Qingdao Bright Chemical, Haihang Group, Qingdao Jiahua Chemical, Zhengzhou Yinyue Chemicals, ShouGuang Haimeng Chemical, Qingdao ZKHT Chemical, Shandong Chuangying Chemical, Heze Development Zone Kaisheng Chemical, Jinan Guriute Chemical, Sanheyuan Chemical, etc.

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Exclusive details pertaining to the contribution that every firm has made to the industry have been outlined in the study. Not to mention, a brief gist of the company description has been provided as well.

Substantial information subject to the production patterns of each firm and the area that is catered to, has been elucidated.

The valuation that each company holds, in tandem with the description as well as substantial specifications of the manufactured products have been enumerated in the study as well.

The Methyl Thioglycolate market research study conscientiously mentions a separate section that enumerates details with regards to major parameters like the price fads of key raw material and industrial chain analysis, not to mention, details about the suppliers of the raw material. That said, it is pivotal to mention that the Methyl Thioglycolate market report also expounds an analysis of the industry distribution chain, further advancing on aspects such as important distributors and the customer pool.

The Methyl Thioglycolate market report enumerates information about the industry in terms of market share, market size, revenue forecasts, and regional outlook. The report further illustrates competitive insights of key players in the business vertical followed by an overview of their diverse portfolios and growth strategies.

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Some of the Major Highlights of TOC covers:

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Measuring the Impact: Demand for Integrated Circuit Tag (IC Label) Product Augmented by Global Outbreak of COVID-225 3w Market News Reports – 3rd…

§ May 10th, 2020 § Filed under Nano Medicine Comments Off on Measuring the Impact: Demand for Integrated Circuit Tag (IC Label) Product Augmented by Global Outbreak of COVID-225 3w Market News Reports – 3rd…

The global Integrated Circuit Tag (IC Label) market study presents an all in all compilation of the historical, current and future outlook of the market as well as the factors responsible for such a growth. With SWOT analysis, the business study highlights the strengths, weaknesses, opportunities and threats of each Integrated Circuit Tag (IC Label) market player in a comprehensive way. Further, the Integrated Circuit Tag (IC Label) market report emphasizes the adoption pattern of the Integrated Circuit Tag (IC Label) across various industries.

The Integrated Circuit Tag (IC Label) market report examines the operating pattern of each player new product launches, partnerships, and acquisitions has been examined in detail.

The report on the Integrated Circuit Tag (IC Label) market provides a birds eye view of the current proceeding within the Integrated Circuit Tag (IC Label) market. Further, the report also takes into account the impact of the novel COVID-19 pandemic on the Integrated Circuit Tag (IC Label) market and offers a clear assessment of the projected market fluctuations during the forecast period.

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Market Segment Analysis The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type Active Passive

Segment by Application Food Medicine Cosmetics Industrial Others

Global Integrated Circuit Tag (IC Label) Market: Regional Analysis The report offers in-depth assessment of the growth and other aspects of the Integrated Circuit Tag (IC Label) market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America. The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region. Global Integrated Circuit Tag (IC Label) Market: Competitive Landscape This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019. The major players in the market include Alien Technology, Atmel, Confidex Ltd, GAO RFID, HID Global Corporation, RF Code, Honeywell International, CoreRFID, Omni-ID, Ageos, Invengo Information Technology, NXP Semiconductors N.V., Smartrac N.V., The Tag Factory, Liujiayi Intelligent Technology, etc.

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The Integrated Circuit Tag (IC Label) market report offers a plethora of insights which include:

The Integrated Circuit Tag (IC Label) market report answers important questions which include:

The Integrated Circuit Tag (IC Label) market report considers the following years to predict the market growth:

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Why Choose Integrated Circuit Tag (IC Label) Market Report?

Integrated Circuit Tag (IC Label) Market Reportfollows a multi- disciplinary approach to extract information about various industries. Our analysts perform thorough primary and secondary research to gather data associated with the market. With modern industrial and digitalization tools, we provide avant-garde business ideas to our clients. We address clients living in across parts of the world with our 24/7 service availability.

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Major Companies in Catheter Laminating Machine Market Struggle to Fulfil the Extraordinary Demand Intensified by COVID-225 3w Market News Reports -…

§ May 10th, 2020 § Filed under Nano Medicine Comments Off on Major Companies in Catheter Laminating Machine Market Struggle to Fulfil the Extraordinary Demand Intensified by COVID-225 3w Market News Reports -…

Companies in the Catheter Laminating Machine market are vying suggestive steps to tackle the challenges resulting from the COVID-19 (Coronavirus) pandemic. Exhaustive research about COVID-19 is providing present-day techniques and alternative methods to mitigate the impact on Coronavirus on the revenue of the Catheter Laminating Machine market.

The report on the Catheter Laminating Machine market provides a birds eye view of the current proceedings and advancements within the Catheter Laminating Machine landscape. Further, the report ponders over the various factors that are likely to impact the overall dynamics of the Catheter Laminating Machine market over the forecast period (20XX-20XX) including the current trends, business expansion opportunities and restraining factors amongst others.

As per the market report suggested by marketresearchhub.us, the global Catheter Laminating Machine market is expected to register a CAGR growth of ~XX% during the forecast period and attain a value of ~US$XX by the end of 20XX. Further, the report suggests that the growth of the Catheter Laminating Machine market is largely influenced by a range of factors including, emphasis on R&D innovations by market players, surging investments to increase product portfolio, and favorable regulatory policies among others.

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Questions Related to the Catheter Laminating Machine Market Explained:

Competitive Landscape

The report provides critical insights related to the leading players operating in the Catheter Laminating Machine market. The revenue generated, market presence, product range, and financials of each company are enclosed in the report.

Market Segment Analysis The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type Vertical Laminator Horizontal Laminator

Segment by Application Internal Medicine Surgical Department

Global Catheter Laminating Machine Market: Regional Analysis The report offers in-depth assessment of the growth and other aspects of the Catheter Laminating Machine market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America. The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region. Global Catheter Laminating Machine Market: Competitive Landscape This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019. The major players in the market include Machine Solutions, Engineering By Design, Ward Automation, ADAPT Automation, Innova Design, Cbmedicals, etc.

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Regional Landscape

The regional landscape of the report provides resourceful insights related to the revenue share analysis of the Catheter Laminating Machine market in different regions. Further, the market attractiveness of each region provides players a clear understanding of the overall growth potential in each regional market.

End-User Analysis

The report provides an in-depth understanding of the various end-users of the Catheter Laminating Machine along with the market share, size, and revenue generated by each end-user.

Important Information that can be extracted from the Report:

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COVID-19 Outbreak Briefly Derails Macroscopic Imaging Workstations Market; Sales to Pick up Pace Once the Pandemic Begins to Recede – Jewish Life News

§ May 10th, 2020 § Filed under Nano Medicine Comments Off on COVID-19 Outbreak Briefly Derails Macroscopic Imaging Workstations Market; Sales to Pick up Pace Once the Pandemic Begins to Recede – Jewish Life News

Detailed Study on the Global Macroscopic Imaging Workstations Market

A recent market study throws light on some of the leading factors that are likely to influence the growth of the Macroscopic Imaging Workstations market in the upcoming decade. The well-researched market study touches upon the growth potential of various budding market players in the current Macroscopic Imaging Workstations market landscape. Moreover, established players, stakeholders, and investors can leverage the data in the report to formulate effective growth strategies.

As per the report, the Macroscopic Imaging Workstations market is forecasted to reach a value of ~US$XX by the end of 2029 and grow at a CAGR of ~XX% through the forecast period (2019-2029). The key dynamics of the Macroscopic Imaging Workstations market including the drivers, restraints, opportunities, and trends are thoroughly analyzed in the presented report.

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The Research Aims to Addresses the Following Doubts Pertaining to the Macroscopic Imaging Workstations Market

The report on the Macroscopic Imaging Workstations market provides a birds eye view of the current proceeding within the Macroscopic Imaging Workstations market. Further, the report also takes into account the impact of the novel COVID-19 pandemic on the Macroscopic Imaging Workstations market and offers a clear assessment of the projected market fluctuations during the forecast period. The different factors that are likely to impact the overall dynamics of the Macroscopic Imaging Workstations market over the forecast period (2019-2029) including the current trends, growth opportunities, restraining factors, and more are discussed in detail in the market study.

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Macroscopic Imaging Workstations Market Segmentation

Competitive Landscape

The competitive landscape section of the report elaborates on the recent developments and innovations introduced by prominent players in the Macroscopic Imaging Workstations market. The growth potential, revenue growth, product range, and pricing strategies of each market player in inspected in the report with precision.

End-use Industry Assessment

The report segments the Macroscopic Imaging Workstations market on the basis of end-use industry and offers a detailed understanding of the supply-demand ratio and consumption pattern of the Macroscopic Imaging Workstations in each end-use industry.

Market Segment Analysis The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type Image Acquisition Digital Type

Segment by Application Biological Research Medicine Veterinary Other

Global Macroscopic Imaging Workstations Market: Regional Analysis The report offers in-depth assessment of the growth and other aspects of the Macroscopic Imaging Workstations market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America. The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region. Global Macroscopic Imaging Workstations Market: Competitive Landscape This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019. The major players in the market include 3D Histech, Bait Partner, Hubei Taiva Medical Technologies, Milestone, PerkinElmer, Sakura Finetek Europe, SPOT Imaging Solutions, HealthManagement, etc.

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Essential Findings of the Macroscopic Imaging Workstations Market Report:

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Postdoctoral Fellow in Photo-Sensitive Antibacterial Coating job with THE UNIVERSITY OF HONG KONG | 206272 – Times Higher Education (THE)

§ May 10th, 2020 § Filed under Nanomaterials Comments Off on Postdoctoral Fellow in Photo-Sensitive Antibacterial Coating job with THE UNIVERSITY OF HONG KONG | 206272 – Times Higher Education (THE)

Work type: Full-time Department: Department of Orthopaedics and Traumatology (21000) Categories: Academic-related Staff

Applications are invited for appointment as Post-doctoral Fellow in Photo-sensitive Antibacterial Coating in the Department of Orthopaedics and Traumatology (Ref.: 500141), to commence as soon as possible for three years, with the possibility of renewal.

Applicants should have a Ph.D. degree in biomedical/mechanical engineering, materials science or a related discipline. Proficiency in written and spoken English is mandatory. Knowledge of and experience in photo-responsive nanomaterials would be an advantage. The appointee is expected to conduct basic science and translational research related to antibacterial projects. He/She will also supervise and mentor junior research staff, and publish scientific articles.

A highly competitive salary commensurate with qualifications and experience will be offered, in addition to annual leave and medical benefits.

The University only accepts online applications for the above post. Applicants should apply online and upload an up-to-date C.V., and provide at least one referee's name and contact details. Review of applications will start on June 16, 2020 and continue until August 31, 2020, or until the post is filled, whichever is earlier.

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Collagenous and Lymphocytic Colitis | Johns Hopkins Medicine

§ May 9th, 2020 § Filed under Nano Medicine Comments Off on Collagenous and Lymphocytic Colitis | Johns Hopkins Medicine

Facebook Linkedin Pinterest Print Stomach and Gut

Collagenous and lymphocytic colitis are forms of microscopic colitis that affect the large intestine. The term microscopic colitis is used to describe chronic, watery diarrhea in patients with only microscopic evidence of inflammation.

The main symptom of collagenous colitis and lymphocytic colitis is chronic, watery diarrhea, as often as five to 10 watery bowel movements per day. More than half of patients cannot pinpoint when their symptoms began.

The diarrhea is usually accompanied by cramps and abdominal pain. These episodes rarely occur at night. Patients are commonly given an incorrect diagnosis of irritable bowel syndrome. One key difference is that patients with collagenous/lymphocytic colitis tend to be older and do not have a history of alternating constipation and diarrhea.

A diagnosis of collagenous/lymphocytic colitis begins with a comprehensive physical exam during which you describe your symptoms and medical history. Other diagnostic procedures include:

Routine blood tests will be ordered to look for any abnormalities. Your doctor may also want to collect a stool sample for analysis.

The standard diagnostic procedure for collagenous/lymphocytic colitis is a lower endoscopy to examine the lower gastrointestinal tract. The endoscope or colonoscope is flexible and able to accommodate bends in the colon. A colonoscopy allows your doctor to see the largest area, including anus, rectum and colon.

Preparing for a colonoscopy includes:

Fasting for eight hours prior to the procedure.

Avoiding aspirin for seven days prior to the procedure if a biopsy (removing some tissue for analysis) will be performed. This will minimize the risk of bleeding.

Cleaning your colon using a bowel preparation. Your doctor will give you more details before your procedure.

What to expect during a colonoscopy:

You receive a sedative and are placed on your left side.

The colonoscope is inserted into the rectum and advances through your colon.

The colonoscope transmits images to a video monitor.

Your doctor examines your gastrointestinal tract and performs a biopsy if necessary.

While there is limited research on treating collagenous/lymphocytic colitis, the literature that does exist suggests that medication may bring relief to patients. Learn more about collagenous/lymphocytic colitis treatment at Johns Hopkins.

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COVID-19 Took Black Lives First. It Didn’t Have To. – ProPublica

§ May 9th, 2020 § Filed under Nano Medicine Comments Off on COVID-19 Took Black Lives First. It Didn’t Have To. – ProPublica

In Chicago, 70 of the citys 100 first recorded victims of COVID-19 were black. Their lives were rich, and their deaths cannot be dismissed as inevitable. Immediate factors could and should have been addressed.

ProPublica Illinois is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as theyre published.

Larry Arnold lived less than a mile from a hospital but, stepping out of his South Side apartment with a 103-degree fever, he told the Uber driver to take him to another 30 minutes away.

Charles Miles breathing was so labored when a friend called to check on him that the friend called an ambulance. Still, Miles, a retired respiratory therapist, was reluctant to leave his home.

Close family support had helped Rosa Lynn Franklin recover from a stroke several years ago, but when she was admitted to the hospital in late March, her daughter could do little more than pat her on the back and say goodbye.

All three were among the first people to die of COVID-19 in Chicago, and all three were African American. Their deaths reflect the stunning racial disparity in the initial toll of the virus. Of the citys first 100 recorded victims, 70 were black.

As the pandemic has spread, that gap has narrowed, and Latinos now make up the largest portion of any reported demographic of confirmed cases across Illinois, state data shows. But the disparity in black deaths persists. As of early May, African Americans, who make up just 30% of Chicagos population, are about half of its more than 1,000 coronavirus deaths.

It has been well established that African Americans are dying of COVID-19 at a disproportionate rate in cities across America. ProPublica sought to explore the problem by examining the first 100 recorded deaths in Chicago, a city with a rich and often troubled history on issues of race.

Using a database obtained from the Cook County Medical Examiners Office that listed the names, health and location information of all COVID-19-related deaths, reporters reached out to the families and friends of each person who died. Reporters ultimately spoke with those who knew 22 of the victims; gleaned details about the lives of many others from obituaries and social media posts; and interviewed experts, medical professionals and government officials to understand how and why those first 100 died.

The racial disparities in coronavirus deaths have largely been attributed to endemic and entrenched inequalities in Chicago decades of disinvestment in the predominantly black neighborhoods on the South and West sides that have left residents with fewer jobs, poorer health and diminished opportunities. Those forces often are portrayed as intractable and, during a pandemic, nearly impossible to fix.

Chicago Mayor Lori Lightfoot acknowledged the challenge when she spoke publicly about the disparities last month and announced a plan to address them.

Were not going to reverse this in a moment, overnight, but we have to say it for what it is and move forward decisively as a city, and thats what we will do, she said. This is about health care accessibility, life expectancy, joblessness and hunger.

While all this is true, ProPublicas reporting also revealed other patterns, factors that could and should have been addressed and which almost certainly exist in other communities experiencing similar disparities. Even though many of these victims had medical conditions that made them particularly susceptible to the virus, they didnt always get clear or appropriate guidance about seeking treatment. They lived near hospitals that they didnt trust and that werent adequately prepared to treat COVID-19 cases. And perhaps most poignantly, the social connections that gave their lives richness and meaning and that played a vital role in helping them to navigate this segregated city that can at times feel hostile to black residents made them more likely to be exposed to the virus before its deadly power became apparent.

Many of the first 100 recorded Chicago COVID-19 victims led lives threaded through with community and civic involvement, powerfully connected to their city, to friends and family. Some had led careers of service, like Patricia Frieson, a retired nurse, and Rhoda Hatch, a former teacher, and Carl Redd, a U.S. Army veteran. Their small businesses helped shape their corners of the city; Hardwell Smith, 85, arrived in Chicago as part of the Great Migration from the Jim Crow South and established gas stations and auto repair shops on the South Side. They were church deacons and musicians; doting uncles like 32-year-old Carl White and nurturing mothers like Juliet Davis, who, despite her limited means, fed the homeless who lived under a neighborhood viaduct.

Most of the first 100 lived in majority-black neighborhoods, according to an analysis of medical examiner data; hardest hit were South Shore, Auburn Gresham and Austin, where the median income for 40% or more of the residents in each community is less than $25,000.

Many were already sick, with underlying health conditions. Seventy-eight of them had hypertension and 53 had diabetes. Just 12 had one health condition, and only five people had no comorbidities. James Brooks, a 27-year-old black man, was the youngest to die.

Im not surprised because every natural disaster will peel back the day-to-day covers over society and reveal the social fault lines that decide in some ways who gets to live and who gets to die, said Dr. David Ansell, senior vice president for community health equity at Rush University Medical Center. And in the United States, those vulnerabilities are often at the intersection of race and health.

Ansell, who wrote The Death Gap: How Inequality Kills, has spent decades documenting the life expectancy gap between black and white Chicagoans, which is the largest in the country. Structural racism, concentrated poverty, economic exploitation and chronic stress cause whats known as biological weathering, Ansell said, where the body ages prematurely and results in earlier death.

Who dies first is different for each pandemic, said Dr. Howard Markel, director of the Center for the History of Medicine at the University of Michigan. The coronaviruss earliest victims, he said, were the most vulnerable.

Theyre not quite forgotten, but we dont pay close enough attention to the health and well-being of this segment of the population, he said. Then a microscopic organism comes and topples them over.

They were vulnerable, but their deaths cannot be dismissed as inevitable.

Phillip Thomas, 48, started to feel sick while working a day shift at the Walmart in Evergreen Park. A diabetic, he was cautious about his health, and he reached out to a doctor, who told him to stay home and self-quarantine in case he had the coronavirus.

About a week into his bedrest, Thomas told his sister Angela McMiller that he was having a hard time standing up and was vomiting, no longer able to keep anything down. She encouraged him to go to the emergency room, but he didnt immediately go, citing the doctors advice to stay home.

Within a couple of days, he called an ambulance, which took him to Jackson Park Hospital, where he was intubated. Two days later, on March 29, he died, in the hospital where he was born.

When McMiller next saw her brother, it was at his funeral, which only 10 people could attend because of social distancing requirements. It was devastating, said McMiller. My mother fell down, my brothers cried.

McMiller is upset that her brother was told to stay home when he was sick, particularly considering the additional risks posed by his health history.

It shocked me, she said. He was diabetic.

Since the earliest days of the pandemic, the Centers for Disease Control and Preventions guidelines have emphasized staying home when symptoms are mild. Most people with COVID-19 have mild illness and can recover at home without medical care, the CDC says on its website. It recommends people call a doctor before going to get care in person, unless experiencing emergency signs like trouble breathing, blue lips or chest pain.

But experts told ProPublica that this one-size-fits-all advice does not account for the fact that African Americans are not only more likely to have preexisting conditions that increase their chances of bad outcomes, but also have a long-standing wariness of the health care system.

There is this distrust between black communities and health care systems based on this fraught history of how health care systems have exploited and abused black people, said Dr. Uch Blackstock, an emergency medicine physician in Brooklyn and the founder and CEO of Advancing Health Equity. What happens as a result of that is that patients dont want to interface with the health care system.

In addition, doctors said patients may delay seeking care out of a fear of the medical bills, lack of insurance or transportation barriers all of which underscores the need for targeted guidance. So instead of encouraging staying at home, these doctors want guidance to encourage African American patients to proactively seek care before symptoms get out of hand.

Dr. Mira Iliescu-Levine, a pulmonary critical care doctor at The Loretto Hospital on Chicagos West Side, is concerned that African American and Latino patients are waiting to come to the hospital after their symptoms become too severe.

You end up with an overwhelming clinical picture, almost like a tornado, thats very hard to stop, she said.

She said she wants patients, especially her African American patients with diabetes, obesity and other comorbidities, to seek care when they have innocent symptoms like a cough, runny nose, itchy eyes or low-grade fever.

Earlier treatment does not guarantee a better outcome, she said, but it can give the patient a fighting chance.

Reach out, she said. Dont wait.

Asked whether the CDC would consider tailoring its recommendations to reflect the underlying health conditions and barriers to care in African American communities, a spokesperson said the CDC is collecting data to monitor and track disparities among racial and ethnic groups to help inform decisions on how to effectively address observed disparities. We will continue to update our recommendations as we learn more.

The CDC spokesperson said the agency has increased engagement with organizations and other partners representing and serving racial and ethnic minority groups to identify gaps in the current response efforts, and that people should never avoid emergency rooms or wait to see a doctor if you feel your symptoms are serious.

On the first day, Willie Flake, a 72-year-old mechanic, lost his ability to taste. Then, he lost his appetite. With each new coronavirus symptom he experienced, his sister Betty and her daughter Yolanda pushed him to go to the hospital.

But Flake, who had diabetes, stayed home because he thought his symptoms were not severe enough to go to the emergency room. He soon developed a fever. By the fourth day, he had trouble breathing.

Flake took an ambulance to Rush University Medical Center on March 27, where his condition appeared to stabilize before worsening again.

They say, Dont come in until your fever is high and you cant breathe, Yolanda Flake said. Thats the part where I feel like they failed him. He waited until he couldnt breathe and it was too late.

In the early hours of April 1, his sister and niece put on masks and gloves and looked through the glass window of his hospital room. He had been like a father to Yolanda, attended every graduation, from kindergarten through college, and had recently accompanied her to buy a car for her daughter, his 23-year-old grandniece, LaSeanda.

Yolanda said she wished she could have been with him inside the room, regardless of the risks.

I wanted to touch him, she said. I wanted to talk to him before he took his last breath. I couldnt say it through the glass door.

And then, his heart stopped.

He waited at home, Yolanda said, and he was dying already.

Larry Arnold also waited, not because he was instructed to, but because he didnt trust his neighborhood hospitals.

Two Jackson Park Hospital and South Shore Hospital sit within five minutes of his home. Both are century-old nonprofit facilities that serve majority low-income and uninsured patients on the South Side. When Arnold started to feel sick in mid-March, he worried that if he called an ambulance, it would take him to one or the other. He didnt want to go to either.

What upsets me is that we dont have adequate medical facilities where we can go to and feel like well be cared for, his niece Angelyn Vanderbilt said. Im sure theyre very good people but the consensus in the community is that those hospitals are inadequate and they have been for years.

After his fever didnt subside for a few days, Arnold, who was 70 and had chronic obstructive pulmonary disease, or COPD, knew he couldnt wait any longer, his family said. He got into an Uber with a temperature of 103 and told the driver to take him to Advocate Christ Medical Center in Oak Lawn, some 30 minutes away.

On March 31, 16 days after he was admitted, the nurse put the phone to Arnolds ear one last time.

We told him to be strong and to continue to fight, Vanderbilt said.

He died about an hour later.

People who live on Chicagos South and West sides are often at a geographic disadvantage during medical crises because the hospitals that are closest to them frequently are those with fewer resources.

Illinois Gov. J.B. Pritzker acknowledged the hardships at a press briefing last month. The safety-net hospitals are challenged in our state, and the availability of health care in communities of color has been at a lower quality or lower availability than in other communities, he said.

The citys safety-net hospitals, facilities that serve a large portion of low-income and uninsured patients regardless of their ability to pay, dont have the private-insurance patient base or the cash reserves to fall back on during a pandemic that many larger hospitals have, said Larry Singer, associate professor at the Beazley Institute for Health Law and Policy at Loyola University Chicago School of Law. Some are millions of dollars in the red and housed in aging buildings. And while their mission is a valiant one, he said, they have not been able to respond to the coronavirus as quickly or with the same equipment and staffing.

Theyre trying to fight the same fight as everybody else with one arm tied behind their back, Singer said. They deserve the resources to do an even better job. Im truly impressed by what they are trying to achieve during a time of crisis.

Tim Caveney, president and CEO of South Shore Hospital, said that limited resources is one reason safety-net hospitals have struggled to earn the trust of the communities they serve. Safety net [hospitals] have gotten a bad beat because we dont have much money. Its a funding issue, he said, adding that the pandemic has aggravated South Shores financial issues. Not only have lucrative elective surgeries been postponed, but COVID-19 patients often require complex and lengthy care, which can be expensive.

Black Neighborhoods Are Served by Fewer, Lower-Resourced Hospitals

Safety-net hospitals have more limited resources because a large portion of their patients have low incomes or are uninsured.

Dr. Khalilah Gates, an African American pulmonary and critical care specialist at Northwestern Memorial Hospital who has family on the South Side, said she is painfully aware that some black patients may prefer to wait it out or travel to distant hospitals.

Both of those are very common phenomenons, she said. Not all community hospitals, but many of the community hospitals in those communities lack the resources that offer security to the residents in those areas.

ProPublica spoke with several families who said their loved ones either delayed care because they didnt want to go to neighborhood hospitals or ultimately wound up in those hospitals as a last resort.

Miles, the retired respiratory therapist, had worked for about 40 years at Northwestern Memorial Hospital providing breathing treatments for patients there. When he started feeling sick in mid-March, he knew what resources he might need.

A friend called him on March 22 and heard his labored breathing. He told Miles that he was calling an ambulance, but Miles resisted, in part, because he didnt want to be taken to Jackson Park, the nearest hospital.

He shouldve been in there a week before that, said his sister Roselle Jones. But he was insistent on not going.

The paramedics said that they had to take him to Jackson Park because it was the closest hospital. Miles family asked that he be transferred to another hospital, but once he tested positive for the coronavirus, a doctor told the family that Miles couldnt be moved, Jones said.

By the end of the week, Miles had been sedated and placed on a ventilator. He died on April 3.

We wanted him out of there. We wanted him somewhere he could get some good care, Jones said. The doors should be closed, and the building torn down.

Philman Williams family also said they tried in vain to get him transferred out of Jackson Park after an ambulance took him there. Williams, 70, worked as a doorman at a luxury high-rise where residents dubbed him the Mayor of Michigan Avenue for his charm and good humor. Not only was his doctor at another hospital, but the family worried about the quality of care he would receive.

A day after he was admitted, their concerns were amplified by a news story detailing reports from employees that the hospital did not have enough personal protective equipment, prompting nurses to avoid entering patient rooms.

Nurses who were sick and those afraid to come to work because they had elderly relatives at home have led to staffing shortages, said Kindra Perkins, a representative with National Nurses United, the union that represents nurses at Jackson Park. One day, an ambulance couldnt drop off a patient because there were only two nurses working in the emergency room, she said.

The nurses deserve to have the resources that they need to provide the quality care in that community, and the people in that community are just as important as the folks on the North Side of Chicago, Perkins said.

Margo Brooks-Pugh, a vice president of development at Jackson Park Hospital, did not answer specific questions, but she wrote in an email that the hospital takes patient and staff safety seriously.

Jackson Park Hospital follows all guidelines and standards as related to patient care and safety, she wrote.

Austin, on the West Side, is one of the citys largest and most chronically underserved areas. It has become a hot spot for COVID-19 cases. The Loretto Hospital, a small nonprofit that has been an anchor in the community for more than 90 years, is the primary provider in the area. Like many of the safety-net hospitals in Chicago, it has struggled financially for years.

When Asberry Stoudemire Jr., a 54-year-old diabetic, got a runny nose, then felt his blood sugar levels begin to fall, his family knew he needed to get care quickly. He also had a history of congestive heart failure, which had forced the avid stepper and musician to retire early from his job as a certified nursing assistant. The Loretto Hospital wasnt their first choice or their second. But it was the closest. Within hours of arriving at Loretto, his condition deteriorated so rapidly that he was sedated and intubated.

His daughter Miranda Stoudemire said she had trouble getting a clear sense of what was going on in the 10 days her father spent in the hospitals recently reopened 15-bed ICU. Loretto couldnt afford to keep the unit up and running before the pandemic, a fate hospital administrators said they fear could be repeated without an infusion of cash as the pandemic continues.

He was saying, I know one thing, Im not going to Loretto, she said. But he did, and she is resolute in her belief that her father would have lived longer had he been at a better resourced hospital. His family tried having him transferred but said they were told he was too critical to be moved.

I feel like he didnt even have a chance to fight, she said.

He died March 29.

Mark A. Walker, spokesman for The Loretto Hospital, said that the hospital has the capacity to care for its patients and is doing its best to communicate with families.

This hospital has gone through hard times, he said. Were doing everything we can. Were learning along with everybody else. But better resourced communities dont have to fight for the same divvy of health care resources that we do.

Although L.B. Perry was 78 and suffered from hypertension and diabetes, nothing usually kept him in bed. So when he didnt wake at 6:30 for his morning oatmeal and coffee, his family began to worry.

As he grew weaker and needed help walking to the bathroom, his family urged him to go to the hospital. After a few days, he relented and went to Holy Cross Hospital in Chicago Lawn on the South Side, but he was sent home, his daughter Vernice Perry said.

Thats why Im so upset, she said. He was in the age bracket, and he has all these health conditions, and he had some of the symptoms.

His condition worsened at home, and his daughter said she begged him to let her drive him to another hospital. Four days later, his wife called an ambulance in the early morning of March 30, and he returned to Holy Cross Hospital. He died on April 2.

Dan Regan, a spokesperson for Sinai Health System, did not answer questions about specific patients, citing privacy restrictions. He said that its hospitals, including Holy Cross, are thoroughly prepared for handling the COVID-19 pandemic, having created dedicated COVID-19 teams, using mobile triage trailers outside facilities to handle sick patients, and isolating COVID-19 patients in specialized rooms.

It is worth noting though that the challenging nature of COVID-19 is that patients can look fine at one point and be discharged home with monitoring and follow-up, only to deteriorate and have to return to the hospital, said Regan. This has been seen in many cases nationwide.

At least 110 patients from community hospitals, including Holy Cross, have been transferred to Rush University Medical Center, a large, well-equipped facility that has been touted as having been built for a pandemic.

Theyre really patients that otherwise, in all likelihood, would not survive at those hospitals, said Dr. Paul Casey, Rushs acting chief medical officer. The resources just arent the same. Nor is the ability within critical care to provide a lot of the life-saving therapies.

On April 6, when Mayor Lightfoot publicly announced that the coronavirus was disproportionately affecting the citys black residents, the virus had been in Chicago at least since January, and more than 100 people were dead. The majority were black.

When we talk about equity and inclusion, theyre not just nice notions, Lightfoot said at the time. They are an imperative that we must embrace as a city. And we see this even more urgently when we look at these numbers and this disparity. Its unacceptable. No one should think that this is OK.

That day, the city announced the Racial Equity Rapid Response Team in partnership with West Side United, with a goal to bring a hyper local public health strategy to targeted communities. In the weeks since, the team has held tele-town halls, delivered thousands of door hangers and postcards with targeted information, and distributed 60,000 masks for residents in the predominantly black communities of Austin, Auburn Gresham and South Shore.

Dr. Allison Arwady, the citys public health commissioner said in an interview that officials had worked behind the scenes to combat rumors that black people couldnt contract the coronavirus, reaching out to community and faith leaders on the South and West sides in February and March to let them know the city was seeing cases across all races.

Arwady said the department at first hoped to contain the spread. It had tracked the cases for weeks as the virus crept through the city, and then exploded. By the end of March, more than 40 Chicagoans had died from the virus, according to the county medical examiner data, though the city said its tally of deaths was less than half of that.

For the most part, Lightfoot has received plaudits for her handling of the pandemic. Illinois was one of the first states in the country to release statistics on COVID-19 deaths by race. Lightfoot herself has even become something of a national political star, with viral videos and memes of her urging residents to stay home. She also gave several high-profile interviews discussing the disproportionate impact of COVID-19 on black communities and emphasizing the importance of tracking demographic data.

The city also encountered some challenges. Early on, it found that up to 30% of the testing data it collected didnt list race. At the April 6 press conference, which came one day after a WBEZ news report detailed the death disparities, the city released a detailed race analysis. The city also issued a public health order mandating demographic data of COVID-19 cases be reported in hopes of being better able to track and assist individuals and communities falling victim to the coronavirus.

Still, to some in the community, the city appeared a step behind. Niketa Brar, co-founder and executive director at Chicago United for Equity, which advocates for racial equity in the city, said officials didnt do enough to engage the communities they knew would be hardest hit. As soon as the virus entered Chicago, she said, the city should have used racial, health and economic data to predict where it would take hold and then begin working with residents in those communities on how best to protect and support them. The Racial Equity Rapid Response Team was dispatched much later, she said.

Excerpt from:
COVID-19 Took Black Lives First. It Didn't Have To. - ProPublica

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The Psychological Toll of Working on the Front Lines: Dr. Sanjay Gupta’s coronavirus podcast for May 6 – CNN

§ May 9th, 2020 § Filed under Nano Medicine Comments Off on The Psychological Toll of Working on the Front Lines: Dr. Sanjay Gupta’s coronavirus podcast for May 6 – CNN

You can listen on your favorite podcast app or read the transcript below.

Jake Tapper, CNN Anchor, "The Lead" and "State of the Union": Doctors and nurses risking their lives to save you and me and patients.

Dr. Ken Duckworth, chief medical officer, National Alliance of Mental Illness: I do worry about our first responders and health care workers, in terms of the trauma they are exposed to.

Ana Cabrera, CNN Anchor: Even physicians are victims of this unprecedented public emergency.

Dr. Sanjay Gupta: Since the beginning of this pandemic, health care workers have been dealing with this virus head-on, putting their own physical health at risk.

According to a CDC [Centers for Disease Control and Prevention] report released in April, more than 9,0000 health care workers have been infected with the coronavirus. ... And because of the limited data we have, that number is likely higher.

But we shouldn't forget the other risks our health care workers are facing. I'm talking about the emotional and psychological ones.

[Pots and pans banging, people cheering for health care workers]

Gupta: Every night in cities around the world, we celebrate our health care workers. But the thing is, even before this pandemic, their jobs were demanding.

They're in high-stress life-and-death situations with long hours.

So in this episode, I want to talk about the pandemic's psychological cost to the people on the front lines -- and what's being done to help them.

I'm Dr. Sanjay Gupta, CNN's chief medical correspondent. And this is "Coronavirus: Fact vs. Fiction."

Dr. Philip Breen: She was a doctor. Every bit of the word that a doctor should be. She put her life on the line to take care of other people.

Last week, Dr. Breen, a New York City emergency room doctor, died by suicide.

She had actually contracted Covid-19 herself. After recovering she went back to work.

Breen: She was like the fireman who runs into the burning building to save another life and doesn't regard anything about herself.

Gupta: There is so much about this virus that is new and unfamiliar, making everyday life more challenging.

I've heard that from my colleagues.

Every day they wonder: Are they safe? And if their families and loved ones are safe as well.

I recently spoke with Dr. Steven McDonald. He's an ER doctor at the same hospital as Dr. Breen.

He's been on the front line for weeks, taking care of patient after patient ... after patient. New York has been the US' pandemic epicenter, with more than 321,000 people infected and 25,000 deaths.

I asked Dr. McDonald about how he's coping with his everyday reality as well as the loss of a colleague, and how he's taking care of his own mental health.

Gupta: So how is life, Dr. McDonald?

Dr. Steven McDonald: First of all, things are changing day-to-day. I think life a month ago looked very different than only two weeks ago than it does today. Thankfully, emergency department volumes are significantly down.

But also, as you can imagine, the tenor of my department is depressed. We just lost one of our faculty members, one of our physicians. And so there's definitely a pall that's been cast over my department -- in addition to this pandemic.

Gupta: I'm so sorry to hear that. I don't think people always recognize both the physical and psychological toll on frontline workers like yourself. At what point for you did it become something that was personally frightening?

McDonald: As we were approaching the peak, I would walk into the emergency room and it was in a state of chaos. And it was overwhelming to an extent that I had never really seen before. It felt -- I keep describing it as though a caged animal had been kind of let loose, and no one could see it or get it back into the cage.

Gupta: Wow. You know, I've been -- I finished med school in 1993, so I've been doing this for a long time. And typically, you know, the family is there. There's an additional line of support.

But what you're describing is people who are coming in, almost always by themselves because families can't come in. And now they find themselves in a position where they may suddenly die. It's tough. I don't mean to paint it so stark, but it sounds like that is the reality, at least in some of these situations.

Let me ask: How worried were you about contracting the virus yourself?

McDonald: If I'm being honest, you know, early on, I think this was probably mid-March when this was first starting. I had a moment at home by myself, borne out of complete irrationality, where I suddenly was convinced that I was going to die of this. I can't explain to you where that came from. I think it was just maybe having read a couple too many of these cases and having talked to a couple of colleagues who had pronounced young people dead of this.

And I just suddenly was gripped by that conviction. And it was frightening. It was really frightening, just to feel like there's nothing that I can do in this. I have truly no agency over my death in some regard. There's no amount of PPE that will protect me from this. And I know that to be irrational. I know that to not be true, but I was so gripped by it in one moment.

Gupta: I agree with you, and I think that's a really interesting way to put it. You know, we do all the right things, but there are things in life, especially with a microscopic virus that's inexplicable. So you're really putting yourself at risk.

McDonald: Right.

Gupta: Did you ever think about sitting it out? Saying, you know what? It's not worth it.

McDonald: You know, I did have a moment where -- I think it was a Sunday night and I had my first shift in a couple of weeks on the Monday. And I was, to be totally honest with you, I was a wreck. I was a wreck. I was calling family and friends. And I was really upset.

And I was thinking about the number of people who I was going to have to pronounce dead or have to have end-of-life conversations with. And I found it so overwhelming in the abstract on that Sunday night.

I thankfully have a great support network, a great therapist -- and spoke with her a bit and was able to sort of pull myself together and work and be a physician the next day. But that was a difficult 24 hours.

Gupta: You know, Steven, it's always struck me that even within the medical community, there is still a stigma about seeking therapy, seeking mental health support. Yet it's so important, maybe never more important, than it is right now.

Do you sense that stigma? I mean, has it manifested at all in your life?

McDonald: I mean, you know, absolutely. I would say physicians don't talk about mental health issues. I don't know if any job is really that open about this, but I think medicine in general breeds a culture of silence about this.

Gupta: And you do hear about physicians who die by suicide. Compared to the general community, it's typically higher across the board.

There was a lot of news about Dr. Breen lately. And I know you knew her somewhat. When you heard this, were you surprised?

McDonald: Absolutely. I was completely floored. She always -- again, I only knew her in a professional capacity, but she struck me as someone who was so self-possessed and so capable, really tough as nails and able to deal with any situation head-on.

And, you know, I esteem all of my colleagues as being that tough.

Gupta: Has there been anything good that's come out of this for you?

McDonald: So I think there has been incredible camaraderie among physicians. At the peak of this, we had orthopedists and urologists coming down and managing critically ill patients and doing blood draws and doing things that are way below their level of training just to help out, and to see colleagues who were so willing to be part of this effort was really inspiring.

You know, secondly, and I think this remains to be borne out, but one hope that I have: This virus, I think is sort of peeling back the onion skin and showing us at the core of American society, things that really need attention on a federal and legislative level.

So, the inequalities that this is exposing, the problems in the health care system that this is exposing.

And I hope that these are conversations that are started and carry weight and are not forgotten after we beat this thing.

Gupta: Camaraderie as well, you're absolutely right about -- I've seen that in our own hospital. Although it does make me think of this joke that you probably heard: the definition of a double-blind study?

McDonald: No?

Gupta: Two orthopedic surgeons trying to read an EKG.

McDonald: Hahahaha. I love that. I will not be telling that to my orthopedic colleagues, but I love that.

Gupta: I want to ask you about, you know, if there's been a best moment and a worst moment.

McDonald: Yes. Worst moment for me was. ... It was during the peak, and I was coming into a shift. I received sign-out on probably 40 patients who were all critically ill.

And so I was in this awful situation where I was pulled into one room to be with a critical patient who was dying. And then the nurse comes and gets me and says, you also have a critical patient who's dying in this other room.

And so I run through to this other room, and this woman is near death. Her heart has nearly stopped. Her oxygen levels are falling. She's already on a ventilator. She was in her late 80s.

And the team is, the team of residents is looking to me, to ask: What are we going to do when this woman's heart stops, as it appears it's going to in the next 10 seconds, 15 seconds? And this woman had no established advanced directives. And we had made multiple attempts to get in touch with family and were unable to.

And, you know, all the data shows that someone of this age who's already on a ventilator, this person is not going to live no matter what interventions you make. And so, talking to you now, it seems very obvious to not attempt to prolong life. But in that moment, it was very hard for me to make that decision. It was -- there was no clarity about it.

And so, I declined to perform CPR. But then I felt terribly about that in the moment. That was really the lowest moment I've had during this, where I just felt like I ended someone's life without any data.

I guess, in terms of bright spots of this -- so you're familiar, I'm sure, with the 7 o'clock clap for providers and essential workers. And so, after Lorna Breen's passing, I was working that next day. And we did at 7 o'clock go out to the front of the emergency department.

All the doctors who were able and the nurses and everyone, and we just had a hell of a clap for those whom we've lost. And it doesn't in any way redeem what's happened. But it was a really nice moment of camaraderie and to celebrate the accomplishments of those whom we've lost, including Dr. Breen.

Gupta: Wow. Well, I mean, going back to the worst moment for a second, for what it's worth, Steven, that was a tough decision. I'm sorry that obviously left such a mark on you. But from what you described, you know, it was the correct decision.

McDonald: Thank you.

Gupta: Do you worry that you're suffering from post-traumatic stress?

McDonald: It's hard to say. I mean, I think like post-traumatic stress disorder, when you're in the thick of it, you don't think about it. And it's only once things calm down that you begin to have things like flashbacks or intrusive thoughts.

So far, I've been very fortunate in that I have not had those symptoms, but I can't tell you with any certainty that I won't in the future. And so that is a perpetual source of anxiety and concern.

Gupta: Well, I mean, I will clap harder and cheer even louder after hearing your story about how that made you feel. I mean, it's the least I think that people can do and people really owe you a debt of gratitude. So, thank you very much.

There'll be books written about the sort of work that you've done. I know you're in the midst of it right now, so it's hard to sense that, but thank you.

McDonald: Thank you. Thank you so much.

Gupta: Like Dr. McDonald said, doctors are facing so many challenges right now. There are these long, demanding shifts, the risk of exposure to the virus and the number of patients that are dying, which is unlike anything we have ever dealt with before.

Dr. John Krystal, Yale University professor of psychiatry and neuroscience and Yale-New Haven Hospital chief of psychiatry: You know you think of the first wave of illness being the wave of patients coming in and presenting with illness. But for these health care workers, the stresses are somewhat cumulative.

And so you can think of a second wave of stress coming through for the Covid health care workers.

Gupta: That was Dr. John Krystal. He heads the psychiatry department at both Yale University and Yale-New Haven Hospital. He's been tasked with leading a group that identifies health care providers who are struggling and provides them with support.

Krystal: One kind of support that we have is giving people a place they can drop into any day they want, every day, five days a week. We have what we call stress and resilience town halls. They're open to everybody in the community: staff, trainees, doctors.

The idea was they should connect to deal with the isolation that they're often feeling. They should unload, you know, they should just share what it is that they're going through and then to learn a few skills. And so we teach people relaxation skills, and we teach people sleep hygiene. And so far, I think in our community, over 1,400 people have made use of them.

Gupta: Dr. Krystal and his team also established a buddy system -- pairing health care workers with their peers. And then they dispatched volunteers to provide psychological support to anyone who wants it, over the phone.

But both Dr. Krystal and Dr. McDonald bring up a more deeply rooted issue about the culture of medicine.

Krystal: You know, some of the challenges are that some of the characteristics that we have historically admired most about physicians: They're willing to sacrifice themselves for others, their reluctance to complain about things.

All of those are admirable, wonderful traits, but somehow, we haven't always inculcated in the values of our medical system that self-care is as much a duty and a responsibility as caring for the patient.

And my hope is that this is an opportunity to have broader discussion about that. And to make it OK for more doctors who need help to seek help.

Gupta: This pandemic has really tried and tested the best of us.

But I am thankful that mental health services are available for our doctors and medical workers who need it the most.

A fund was recently set up in honor of Dr. Breen -- it's called the Dr. Lorna Breen Heroes' Fund, and it's there to provide mental health services to medical workers.

It's my sincere hope that the support that's been marshaled to help health care workers in this pandemic will last beyond this moment -- that they'll become a fixture in the way we think about care.

We'll be back tomorrow. Thanks for listening.

If you have questions, please record them as a voice memo and email them to asksanjay@cnn.com -- we might even include them in our next podcast.

You can also head to cnn.com/coronavirus and sign up for our daily newsletter, which features the latest updates on this fast-moving story from CNN journalists around the globe. For a full listing of episodes of "Coronavirus: Fact vs. Fiction," visit the podcast's page here.

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The Psychological Toll of Working on the Front Lines: Dr. Sanjay Gupta's coronavirus podcast for May 6 - CNN

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Tanning Beds Market Report Outlining the Current State of the Market by 2020-2027 Along with Key Players ProSun International, L & C Distributing,…

§ May 9th, 2020 § Filed under Nano Medicine Comments Off on Tanning Beds Market Report Outlining the Current State of the Market by 2020-2027 Along with Key Players ProSun International, L & C Distributing,…

Tanning Beds Market is a comprehensive report on the global market provides in-depth insight into the industry covering all the important parameters and analyzes that provide qualitative insight into the factors that affect Global Tanning Beds Market growth. Includes all regions and countries in the world that show regional development status including market size.

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The report also summarized the high revenue generated with market facts and figures across regions such as North America, Japan, Europe, Asia, and India. We focus on the key issues needed to have a positive impact on the market, such as policy, international trade, and speculation, and supply-demand in the Global Tanning Beds Market.

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If You Have Any Query, Ask Our Experts: https://www.healthcareintelligencemarkets.com/enquiry_before_buying.php?id=140890

Table of Contents:

Chapter 1: Global Tanning Beds Market Overview Chapter 2: Global Economic Impact on Industry Chapter 3: Production, Revenue (Value) by Region Chapter 4: Supply (Production), Consumption, Export, Import by Regions Chapter 5: Production, Revenue (Value), Price Trend by Type Chapter 6: Global Tanning Beds Market Analysis by Application Chapter 7: Manufacturing Cost Analysis Chapter 8: Industrial Chain, Sourcing Strategy and Downstream Buyers Chapter 9: Marketing Strategy Analysis, Distributors/Traders Chapter 10: Market Effect Factors Analysis Chapter 11: Global Tanning Beds Market Forecast

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Tanning Beds Market Report Outlining the Current State of the Market by 2020-2027 Along with Key Players ProSun International, L & C Distributing,...

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Major Companies in Cumin Seed Market Struggle to Fulfil the Extraordinary Demand Intensified by COVID-224 – 3rd Watch News

§ May 9th, 2020 § Filed under Nano Medicine Comments Off on Major Companies in Cumin Seed Market Struggle to Fulfil the Extraordinary Demand Intensified by COVID-224 – 3rd Watch News

Companies in the Cumin Seed market are vying suggestive steps to tackle the challenges resulting from the COVID-19 (Coronavirus) pandemic. Exhaustive research about COVID-19 is providing present-day techniques and alternative methods to mitigate the impact on Coronavirus on the revenue of the Cumin Seed market.

The report on the Cumin Seed market provides a birds eye view of the current proceedings and advancements within the Cumin Seed landscape. Further, the report ponders over the various factors that are likely to impact the overall dynamics of the Cumin Seed market over the forecast period (20XX-20XX) including the current trends, business expansion opportunities and restraining factors amongst others.

As per the market report suggested by ResearchMoz.us, the global Cumin Seed market is expected to register a CAGR growth of ~XX% during the forecast period and attain a value of ~US$XX by the end of 20XX. Further, the report suggests that the growth of the Cumin Seed market is largely influenced by a range of factors including, emphasis on R&D innovations by market players, surging investments to increase product portfolio, and favorable regulatory policies among others.

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Competitive Landscape

The report provides critical insights related to the leading players operating in the Cumin Seed market. The revenue generated, market presence, product range, and financials of each company are enclosed in the report.

Market Segment Analysis The research report includes specific segments by Type and by Application. This study provides information about the sales and revenue during the historic and forecasted period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth. Segment by Type, the Cumin Seed market is segmented into Purity 98% Purity 99% Purity 99.5%

Segment by Application Food Medicine

Global Cumin Seed Market: Regional Analysis The Cumin Seed market is analysed and market size information is provided by regions (countries). The report includes country-wise and region-wise market size for the period 2015-2026. It also includes market size and forecast by Type and by Application segment in terms of sales and revenue for the period 2015-2026. The key regions covered in the Cumin Seed market report are: North America U.S. Canada Europe Germany France U.K. Italy Russia Asia-Pacific China Japan South Korea India Australia Taiwan Indonesia Thailand Malaysia Philippines Vietnam Latin America Mexico Brazil Argentina Middle East & Africa Turkey Saudi Arabia U.A.E Global Cumin Seed Market: Competitive Analysis This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and sales by manufacturers during the forecast period of 2015 to 2019. The major players in global Cumin Seed market include: Savaliya Agri Commodity Moonlite Foods Kore Agro ABHYUDAY INDUSTRIES Ashapurna Spices Mahavir Shimla Hills Offerings

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End-User Analysis

The report provides an in-depth understanding of the various end-users of the Cumin Seed along with the market share, size, and revenue generated by each end-user.

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IonQ CEO Peter Chapman on how quantum computing will change the future of AI – VentureBeat

§ May 9th, 2020 § Filed under Quantum Computer Comments Off on IonQ CEO Peter Chapman on how quantum computing will change the future of AI – VentureBeat

Businesses eager to embrace cutting-edge technology are exploring quantum computing, which depends on qubits to perform computations that would be much more difficult, or simply not feasible, on classical computers. The ultimate goals are quantum advantage, the inflection point when quantum computers begin to solve useful problems, and quantum supremacy, when a quantum computer can solve a problem that classical computers practically cannot. While those are a long way off (if they can even be achieved), the potential is massive. Applications include everything from cryptography and optimization to machine learning and materials science.

As quantum computing startup IonQ has described it, quantum computing is a marathon, not a sprint. We had the pleasure of interviewing IonQ CEO Peter Chapman last month to discuss a variety of topics. Among other questions, we asked Chapman about quantum computings future impact on AI and ML.

The conversation quickly turned to Strong AI, or Artificial General Intelligence (AGI), which does not yet exist. Strong AI is the idea that a machine could one day understand or learn any intellectual task that a human being can.

AI in the Strong AI sense, that I have more of an opinion just because I have more experience in that personally, Chapman told VentureBeat. And there was a really interesting paper that just recently came out talking about how to use a quantum computer to infer the meaning of words in NLP. And I do think that those kinds of things for Strong AI look quite promising. Its actually one of the reasons I joined IonQ. Its because I think that does have some sort of application.

In a follow-up email, Chapman expanded on his thoughts. For decades it was believed that the brains computational capacity lay in the neuron as a minimal unit, he wrote. Early efforts by many tried to find a solution using artificial neurons linked together in artificial neural networks with very limited success. This approach was fueled by the thought that the brain is an electrical computer, similar to a classical computer.

However, since then, I believe we now know, the brain is not an electrical computer, but an electrochemical one, he added. Sadly, todays computers do not have the processing power to be able to simulate the chemical interactions across discrete parts of the neuron, such as the dendrites, the axon, and the synapse. And even with Moores law, they wont next year or even after a million years.

Chapman then quoted Richard Feynman, who famously said Nature isnt classical, dammit, and if you want to make a simulation of nature, youd better make it quantum mechanical, and by golly its a wonderful problem, because it doesnt look so easy.

Similarly, its likely Strong AI isnt classical, its quantum mechanical as well, Chapman said.

One of IonQs competitors, D-Wave, argues that quantum computing and machine learning are extremely well matched. Chapman is still on the fence.

I havent spent enough time to really understand it, he admitted. There clearly is a lot of people who think that ML and quantum have an overlap. Certainly, if you think of 85% of all ML produces a decision tree. And the depth of that decision tree could easily be optimized with a quantum computer. Clearly theres lots of people that think that generation of the decision tree could be optimized with a quantum computer. Honestly, I dont know if thats the case or not. I think its still a little early for machine learning, but there clearly is so many people that are working on it. Its hard to imagine it doesnt have application.

Again, in an email later, Chapman followed up. ML has intimate ties to optimization: many learning problems are formulated as minimization of some loss function on a training set of examples. Generally, Universal Quantum Computers excel at these kinds of problems.

Chapman listed three improvements in ML that quantum computing will likely allow:

Strong AI or ML, IonQ isnt particularly interested either. The company leaves that part to its customers and future partners.

Theres so much to be to be done in a quantum, Champan said. From education at one end all the way to the quantum computer itself. I think some of our competitors have taken on lots of the entire problem set. We at IonQ are just focused on producing the worlds best quantum computer for them. We think thats a large enough task for a little company like us to handle.

So, for the moment were kind of happy to let everyone else work on different problems, he added. We just think, producing the worlds best quantum computer is a large enough task. We just dont have extra bandwidth or resources to put into working on machine learning algorithms. And luckily, theres lots of other companies that think that theres applications there. Well partner with them in the sense that well provide the hardware that their algorithms will run on. But were not in the ML business per se.

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Kerry Emanuel, David Sabatini, and Peter Shor receive BBVA Frontiers of Knowledge awards – MIT News

§ May 9th, 2020 § Filed under Quantum Computer Comments Off on Kerry Emanuel, David Sabatini, and Peter Shor receive BBVA Frontiers of Knowledge awards – MIT News

The BBVA Foundation awarded three MIT professors Frontiers of Knowledge Awards for their work in climate change, biology and biomedicine, and quantum computation. Department of Earth, Atmospheric, and Planetary Sciences Professor Kerry A. Emanuel, Department of Biology Professor David Sabatini, and Department of Mathematics Professor Peter Shor were recognized in the 12th edition of this annual award.

Kerry Emanuel

Emanuel, the Cecil and Ida Green Professor of Atmospheric Science, earned the BBVAs Climate Change award for his fundamental contributions to the understanding of tropical cyclones and how they are affected by climate change, according to the committees citation. By understanding the essential physics of atmospheric convection he has unraveled the behavior of tropical cyclones hurricanes and typhoons as our climate changes. He was also lauded for extraordinary effectiveness in communicating the science of climate change to the public and policymakers.

Emanuel is the co-founder (with Daniel H. Rothman) and co-director of the MIT Lorenz Center, a climate think tank that fosters creative approaches to learning how climate works. He was the first to link greater hurricane intensity to climate change-induced warming of sea surface waters.

It is hard to imagine an area of climate science where one persons leadership is so incontestable, says Bjorn Stevens, BBVA Foundation committee chairman and director of the Max Planck Institute for Meteorology.

Hurricanes have long been known as destructive natural events, but the underlying physics of them was still largely unknown. Throughout the 1980s and 1990s, after completing degrees at MIT and later joining the EAPS faculty, Emanuel pinned down the mechanisms behind hurricanes. In his research detailing how warming surface oceans fuel storms and increase the intensity, he called them massive, natural machines that convert the heat they extract from the ocean into wind energy.

A changing climate will see more powerful hurricanes. Emanuel warns that this will complicate the already-tough task of making accurate forecasts, and predicts that hurricanes will spread into more regions of the planet.

His models currently predict a 5 percent increase in hurricane intensity (i.e., wind speed) for each 1-degree rise in ocean temperatures. Three degrees of warming would makehurricanes 15 percent more intense, but their destructive potential would actually triple; in other words, with this15percent increasein wind speed, thedamage would increase by around 45 percent, says Emanuel, the author of "Divine Wind: The History and Science of Hurricanes" (Oxford Unviersity Press, 2005) and "What We Know about Climate Change" (MIT Press, 2018).

Todays most intense hurricanes may have a wind speed at the surface of 85 meters per second, but by the end of this century, unless we curb greenhouse gas emissions, we could start to see speeds of up to 90-92 meters per second. A hurricanes destructive potential is determined by its wind speed, so in fact, the destructiveness of these storms for human populations would be considerably greater.

Emanuel says that the international community is not doing nearly enough to combat climate change. We need to stop listening to the voices of denial, and instead listen to our own children, who are crying out for us to act.

David Sabatini

Sabatini, an MIT professor of biology and member of the Whitehead Institute for Biomedical Research and the Koch Institute for Integrative Cancer Research, shares his Frontiers of Knowledge Award in Biology and Biomedicine with Michael Hall of the University of Basel, for the discovery of a protein kinase that regulates cellular metabolism and growth.

Their discovery of mTOR is used in the study of a wide array of health conditions, including obesity, aging, cancer, diabetes, epilepsy, Alzheimers, and Parkinsons. Research has suggested that 60 percent of cancers have some mechanism for turning on the mTOR pathway, Sabatini says. I could never have imagined the implications of that first discovery.

Sabatini began his PhD thesis on understanding the mechanism of action of rapamycin, a natural anti-fungal agent proved to have immunosuppressive and anti-cancer properties. It is used to prevent organ rejection in transplant patients.

The two scientists arrived at their findings independently. Hall discovered the target of rapamycin (TOR) protein in yeast cells in 1993 during his time as a senior investigator; Sabatini isolated it in mammals while still a doctoral student, in 1994, and gave it the name mTOR.

In mammalian cells, mTOR which stands for mechanistic target of rapamycin, an immunosuppressant drug that inhibits cell growth is the keystone molecule in a pathway that regulates cellular metabolic processes in response to nutrients.

Sabatini explains that mTOR is a switch that turns on in the presence of nutrients, so the body can build material, and when there are no nutrients available it breaks the material down. The on/off switch of the mTOR switch controls a cascade of hundreds of molecular signals, many of which are still unknown to science.

The molecular mechanisms that regulate the growth of organisms and coordinate it with the availability of nutrients were unknown until two decades ago, said the committee.

After the molecule was isolated in yeast and mammals, both researchers began the task of unraveling its multiple organismal functions. Sabatinis lab has since identified most of the components of the mTOR pathway and shown how they contribute to the function of cells and organisms. His discoveries have opened avenues for identifying disease vulnerabilities and treatment targets for diverse conditions notably including key metabolic vulnerabilities in pancreatic and ovarian cancer cells and neurodevelopmental defects. He is currently working to exploit those vulnerabilities as targets for new therapies.

Rapamycin is used as an immunosuppressant to prevent rejection of transplanted organs and as an anti-cancer agent. In the treatment of cardiovascular diseases, it is used as a coating for coronary stents to stop new blockages forming in the bloodstream.

Because mTOR is a nutrient sensor, additional research points to caloric restriction for increasing longevity. TOR was the first known protein that influences longevity in all of the four species that scientists commonly use to study aging: yeast, worms, flies, and mice. We are just scratching the surface of possible mTOR applications, he says. I dont know if it will help us live to be 120, but I think it will have beneficial effects on different physiological systems, and I am practically sure that it will ameliorate aspects of aging-related diseases.

Peter Shor

Shor, the Morss Professor of Applied Mathematics, was recognized in the Basic Sciences category for his role in the development of quantum computation and cryptology. He shares this award with IBM Researchs chemical physicist Charles H. Bennett and University of Montreal computer scientist Gilles Brassard.

The award committeeremarked on the leap forward in quantum technologies, an advance that draws heavily on the new laureates pioneering contributions. The committee stated that their work spans multiple disciplines and brings together concepts from mathematics, physics, and computer science. Their ideas are playing a key role in the development of quantum technologies for communication and computation.

Bennett and Brassard invented quantum cryptography in the 1980s to ensure the physical inviolability of data communications. The importance of this work became apparent 10 years later when Shor discovered that a hypothetical quantum computer would render effectively useless the conventional cryptography systems underpinning the privacy and security of todays internet communications.

Bennett and Brassards BB84 protocol generally acknowledged as the first practical application of the science of quantum information underpins the security of all our internet communications and transactions, and is based on the existence of mathematical problems that computers cannot solve. Until, as the citation states, Shor discovered that quantum computers could factorize integers much faster than any supercomputer, therefore compromising the security of conventional cryptographic schemes.

Says Brassard, The importance of our work became much more evident after Shor destroyed everything else. Shors Algorithm is now one of the quantum algorithms that comprise the fast-developing language to be spoken by tomorrows quantum computers.

Another of Shors contributions is an algorithm used to correct quantum computer errors, an essential requirement for enabling and scaling quantum computations, the committee wrote.

Quantum computers are exposed to a large volume of noise, causing numerous errors. Everyone thought that you couldnt correct errors on quantum computers, recalls Shor, because as soon as you try to measure a quantum system you disturb it. In other words, if you try to measure the error so as to correct it, you disturb it and computation is interrupted. My algorithm showed that you can isolate and fix the error and still preserve the computation.

Quantum cryptography is one of the most advanced branches of quantum technology, which the laureates view as a long-term prospect. It will be five or 10 years before a quantum computer can do anything approaching useful, says Shor. With time, however, he is convinced that these machines will deliver revolutionary applications. For example, in biomedicine, it takes enormous amounts of computer time to simulate the behavior of molecules, he says. But quantum computers could achieve that, and help design new drugs.

The BBVA Foundation promotes knowledge based on research and artistic and cultural creation, and supports activity on the analysis of emerging issues in five strategic areas: environment, biomedicine and health, economy and society, basic sciences and technology, and culture. The Frontiers of Knowledge Awards, spanning eight prize categories, recognize research and creative work of excellence as embedded in theoretical advances, technological developments, or innovative artistic works and styles, as well as fundamental contributions in addressing key challenges of the 21st century.

Since its launch in 2009, the BBVA also has given awards to MITs Susan Solomon for climate change; Marvin Minsky, Adi Shamir,Silvio Micali,Shafi Goldwasser, and Ronald Rivest for information and computer technologies; Stephen Buchwald for basic sciences; Edward Boyden for biology and biomedicine; and Daron Acemoglu for economics.

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From Upload to Westworld: The Cautionary Tales of Technology-Driven Series – Variety

§ May 9th, 2020 § Filed under Quantum Computer Comments Off on From Upload to Westworld: The Cautionary Tales of Technology-Driven Series – Variety

In the real world, almost every adult has a smart phone in his or her pocket and many also utilize virtual assistants, but more advanced technology from smart thermostats to self-parking cars remain fewer and farther between. The reel world, though, is opting to go beyond reflecting what average citizens have in their lives today, instead telling a sleek but often cautionary tale of the technology of the near future.

Part of what I think is fun about science fiction is getting a little preview of what life might be like and what certain issues might happen if life develops in this direction, says Greg Daniels, who created Upload, Amazon Prime Videos new streaming comedy that follows a young app developer (Robbie Amell) whose memories and consciousness gets uploaded into a digital afterlife so he can, theoretically, live forever.

Upload is just one in a recent wave of new series that are out to explore the deceptive ease emerging technology offers for ones life, while said technology also causes all kinds of new problems. Alex Garlands FX on Hulu limited series Devs is another that specifically looks at the creation of a digital afterlife, raising questions about fate versus free will and whether man should be given so much power at all, while both HBOs Westworld and Foxs upcoming drama Next follow technological creations that evolve well-past their programming.

If all of our thoughts and memories are information a staggering amount of information eventually you should be able to record and capture it all because its a finite amount. So I had this idea if we could reconstitute ourselves in some kind of virtual reality then mankind can create its own afterlife, and wouldnt it have all of the drawbacks of society on Earth? Mankind created it, so it wouldnt be all that fair and it would be capitalistic, says Daniels. What if some people with the means can upload but other people cant, and what if people stop investing in the Earth because they dont care, theyre saving it up for later?

In Devs, a grieving father named Forest (Nick Offerman) stumbles into the power to use quantum computing to determine a persons fate and the ability to send consciousness to a digital afterlife where they can be with their loved ones as if they never died.

The key principle for me with Forest, always, was that he wasnt a tech genius he was someone who was there at the right time, Garland says. If I have a critique of tech geniuses in this show, its that: We confuse lucky entrepreneurs with geniuses. And then the non-genius entrepreneur might believe he is a genius because everyone is telling them so, and thats where the trouble starts.

Devs mixes themes of religion with themes of technology because Garland considers them versions of the same thing: Theyre devotional, theyre faith-based, they make us feel dizzy, they make us feel small, they make us feel comforted, he says, citing the way in which the product launch of a new piece of tech can look like a very excited, feverish church meeting.

All of these shows depict such devotion often leading to great destruction despite even the best of intentions. In Devs, Sergei (Karl Glusman) becomes physically ill when he learns what Forests code really does, and Forest has him killed. (Admittedly, he does resurrect him in that digital afterlife, making him what Garland calls damaged and complicated, rather than a bad guy.) Westworld spent its first two seasons peeling back the layers of both the people who both built and frequented the robot host-filled theme parks that let them play out their wildest childhood dreams, no matter how sadistic they turned out to be, and the hosts themselves as some of them gained awareness of their situation. And in Next, a pair of brothers (played by John Slattery and Jason Butler Harner) fall on opposite sides of what to do about an A.I. that develops into a super-intelligence and begins to manipulate the lives of those who are trying to shut it down.

Even though dramatic license is taken for the level to which these technologies evolve in these stories, the majority of the science is rooted in fact, which requires an ongoing research process, especially as the real world of technology changes over time.

The most science fiction element of the show this season was that people actually reacted to the Incite data leak, says Westworld co-creator and co-showrunner Jonathan Nolan. We understand in the abstract that people are monitoring and surveilling you, having that dumped back on you should have people freaking out but most likely, if I look at the track record, it probably wont. Youre totally fine with the idea that if you get a Gmail account that the algorithm reads your email!

In the third season of the genre-bending drama, former theme park host Dolores (Evan Rachel Wood) sets out in the real world to take down mankind. She creates copies of her own coding and uploads them into other host bodies to do her bidding around the world, and she also sends everyone in the world copies of their files from Incite, a company that has been monitoring their activity and using an algorithm to predict their future based on past behaviors.

The very real blockchain technology is a foundational element in the third season of Westworld. That show features some radical and cinematic technology such as flying vehicles and limbic implants that regulate psychological function, Nolan notes, more commonly, elements that follow current technology trend lines so the writers can talk about is our world right now, he explains. This includes an app that allows the gig economy to be applied to crime, in addition to data monitoring.

Additionally, in Westworld, Engerraund Serac (Vincent Cassel) was able to cement his control over society and reorganize the economy by fixing global warming. But, in order to do so, you would need an A.I., Nolan says. We have created a situation that humans are probably not going to be able to fix; theyre going to need a certain amount of algorithmic help to unf the planet.

Manny Coto, who created and runs Next, says that the development of an A.I. into a super-intelligence now is still speculative, but there are computer scientists that say we are only five years away from something like this happening. For the rest of the technology in the series, he wanted to stay grounded in what more or less average citizens experience on a daily level, he shares. I didnt want this series to take place in the world of tech, so to speak. I wanted a lot of this to take place in our homes because technology advances, but that technology doesnt trickle down to the average person for a while.

This manifests itself in an episode that explores smart lightbulbs that are touted as helping a consumer cut energy costs but can also be used to monitor a person due to the infrared pulses they give off, as well as one that looks into deep fakes, something Coto admits he rushed into the first season as they started to become more prominently discussed in the news media.

Similarly, Garland wanted to ensure that any theories discussed in Devs were real ones so if somebody was going to research it, they would find the show did its best to give a fair account; it wasnt just sexing it up, he says. And when it came to the look of the quantum computer and where it was kept in the company within the show, he consulted with a friend who actually works in artificial intelligence.

The quantum computer at the core of the Devs cube is structured on what an actual quantum computer looks like when you strip away its shell, and the floating cube itself is a mathematical conceit that you often see generated on computers; its a fractal shape, he explains. We had a conversation about, If you had a program or a system that you wanted to keep very, very secret, what are the measures that you would take in order to do that? I remember one of the things he talked about was vacuum seals, as well as having systems that had no plug-in ports.

Whether explicitly through dialogue or simply in the questions the stories raise for the audience, all of these shows invite the discussion of whether or not this technology is enhancing our lives.

For Nolan, the danger comes from assuming the algorithms created to add ease to ones life are doing so in a fair and just way.

Theyre not, he says. Theyre subject to the biases of the people who made them. So in Westworld the question was [about] trusting an A.I. to reorganize the world economy to avoid destroying the world, what happens after that? Having made that deal in Westworld to save us from catastrophic human activity-caused climate change, you put the algorithm in charge, and once you have put the algorithm in charge, can you ever vote it out of office? Its bad now with Facebook, with Google, with the mass of technologies that are completely unregulated and have already had potentially disastrous consequences for democracy.

Regardless of if we should tinker with technology, the fact is that we already are.

Some form of super-intelligence will probably happen. The question is when sooner or later? says Coto. And when it does, its going to transform everything. And it will be a version of who has the atom bomb: Whichever country has the first one will be the country that wins. So how can we prepare?

Perhaps by paying extra close attention to what goes wrong in these stories.

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Journal of Nanotechnology | Hindawi

§ May 9th, 2020 § Filed under Nanotechnology Journal Comments Off on Journal of Nanotechnology | Hindawi

Research Article

28 Mar 2020

Development of Growth Theory for VaporLiquidSolid Nanowires: Wetting Scenario, Front Curvature, Growth Angle, Linear Tension, and Radial Instability

Valery A. Nebolsin|Nada Swaikat|Alexander Yu. Vorobev

In this paper, we report that under wetting conditions (or modes) of nanowire (NW) growth, when a nonplanar crystallization front emerges under a catalyst droplet, a shift in the three-phase line (TPL) of the vaporliquidcrystal interface occurs under thermodynamically stable conditions when the angle with respect to the droplet surface, termed the growth angle, is fixed. The growth angle of the NWs is determined not from a geometrical perspective but on the basis of the physical aspects of the processes occurring around the TPL, revealing a size dependence caused by the influence of linear tension of the three-phase contact of a vaporliquid crystal. The observed radial periodic instability of the NWs is described according to the size dependence of the thermodynamic growth angle, which induces negative feedback in the system. Under the influence of linear tension and positive feedback, the tips or needles of NWs can be formed.

Research Article

13 Feb 2020

Adsorption Capacities of Hygroscopic Materials Based on NaCl-TiO2 and NaCl-SiO2 Core/Shell Particles

Marie Bermeo|Nabil El Hadri|...|Mustapha Jouiad

Hygroscopic materials which possess high moisture adsorption capacity were successfully upgraded by the functionalization of sodium chloride (NaCl) using two nuances of oxides. A procedure was developed to first prepare submicron-sized NaCl crystals; thereafter, these crystals were coated by choice of either titanium dioxide (TiO2) or silica (SiO2) to enhance the hygroscopic properties of NaCl and prevent its premature deliquescence. After coating, several analytical techniques were employed to evaluate the obtained composite materials. Our findings revealed that both composites NaCl-TiO2 and NaCl-SiO2 gave excellent performances by exhibiting interesting hydrophilic properties, compared to the sole NaCl. This was demonstrated by both environmental scanning electron microscope (ESEM) and water vapor adsorption experiments. In particular, NaCl-TiO2 composite showed the highest water adsorption capacity at low relative humidity and at a faster adsorption rate, induced by the high surface energy owing to the presence of TiO2. This result was also confirmed by the kinetics of adsorption, which revealed that not only does NaCl-TiO2 adsorb more water vapor than NaCl-SiO2 or sole NaCl but also the adsorption occurred at a much higher rate. While at room temperature and high relative humidity, the NaCl-SiO2 composite showed the best adsorption properties making it ideal to be used as a hygroscopic material, showing maximum adsorption performance compared to NaCl-TiO2 or sole NaCl. Therefore, NaCl-TiO2 and NaCl-SiO2 composites could be considered as promising hygroscopic materials and potential candidates to replace the existing salt seeding agents.

Research Article

24 Dec 2019

Highly Efficient Photocatalysis by Zinc Oxide-Reduced Graphene Oxide (ZnO-rGO) Composite Synthesized via One-Pot Room-Temperature Chemical Deposition Method

Roselle T. Ngaloy|Aixeen M. Fontanilla|...|Ian Jasper A. Agulo

We synthesized zinc oxide-reduced graphene oxide (ZnO-rGO) composites using a one-pot chemical deposition method at room temperature. Zinc powder and graphene oxide (GO) of different mass ratios (1:1, 1:2, 1:5, 1:10, and 1:20 GO to Zn) were used as precursors in a mildly alkaline solution. UV-Vis spectroscopy was used to study the photocatalytic efficiency of the samples through the photodegradation of methylene blue (MB). UV-Vis measurements show the fast decomposition of methylene blue under UV light illumination with the best degradation efficiency of 97.7% within one hour, achieved with sample ZG2 (1 GO:2 Zn mass ratio). The corresponding degradation rate was kZG2=0.1253min1, which is at least 5.5 times better than other existing works using hydrothermal methods. We argue that the excellent photodegradation of MB by ZG2 is due to the efficient charge separation brought about by the electronic interaction of the rGO with the ZnO and the formation of a Zn-O-C bond, as supported by XRD and Raman spectroscopy measurements.

Research Article

13 Oct 2019

Thermoelectric Effect of Buckypaper/Copper Assembly

Paula Fabola Pantoja Pinheiro|Luiza de Marilac Pantoja Ferreira|...|Marcos Allan Leite dos Reis

Carbon nanotubes (CNTs) exhibit excellent electrical and thermal properties that have been used in several device assemblies, such as electrode sheets made from an aggregate of CNTs, also called as buckypaper (BP). Despite that, the properties of single CNTs are reduced when randomly assembled to form a BP. In this way, this study investigated the thermoelectric effect of a BP electrode assembled on a copper electrode with an active area of 4.0cm2. The micrographs were obtained by scanning electron microscopy and show morphology agglomerated of multiwalled CNTs, which permeated into the filter paper, forming a thickness of 67.33m. Moreover, indoor/outdoor tests were performed approaching the BP electrode from a heat source. Thus, the electrical responses in function of temperature variation show maximum thermovoltages of 9.0mV and 40.73mV from indoor and outdoor tests, respectively. Finally, an average Seebeck coefficient for the BP/copper electrodes array of 35.346.0mV/K was estimated from 298 to 304K. These findings suggest that this assembly will be easily applied in thermoelectric device concepts.

Review Article

01 Jul 2019

Fluoride in Drinking Water and Nanotechnological Approaches for Eliminating Excess Fluoride

Ruwanthi W. Premathilaka|Nalinda D. Liyanagedera

Arising awareness of health hazards due to long-term exposure of fluoride has led researchers to seek for more innovative strategies to eliminate excess fluoride in drinking water. Fluoride-bearing chemicals in both natural and anthropogenic sources contaminate drinking water, which mainly cause for human fluoride ingestion. Hence, developing sustainable approaches toward alleviation is essential. Among many emerging techniques of defluoridation, nanotechnological approaches stand out owing to its high efficiency, and hence, as in many areas, nanotechnology for excess fluoride removal in water is gaining ground compared to other conventional adsorbents and process. The present review focuses on some of the advanced and recent nanoadsorbents including their strengths and shortcomings (e.g., CNT, LDH, graphene-based nanomaterials, and magnetic nanomaterials) and other processes involving nanotechnology while discussing basic aspects of hydrochemistry of fluoride and geological conditions leading for water fluoride contamination. Considering all the findings in survey, it is evident that developing more sustainable techniques is essential rather than conducting batch-type experiments solely.

Research Article

12 Jun 2019

Antagonistic Effects of Sublethal Concentrations of Certain Mixtures of Metal Oxide Nanoparticles and the Bulk (Al2O3, CuO, and SiO2) on Gill Histology in Clarias gariepinus

Amaeze Henry Nnamdi|Tam-Miette Dawarri Briggs|...|Henry Ebele Obanya

Background. The effect of nanoparticles (NPs) on aquatic environments is poorly studied. Aim. This study evaluates the toxicity of joint effects of these different metal nanoparticles and their bulk in mixtures (Al2O3, CuO, and SiO2) on fish using histological biomarker. Materials and Methods. The bulk and nano sizes of three salts (Al2O3, CuO, and SiO2) were used. Nanosizes ranged from 25nm to 100nm. The juvenile fishes of Clarias gariepinus (mean Length: 12.33.5cm; mean weight: 18.526.41g) were used for the acute and chronic toxicity tests. They were exposed to 7mg/L each of the bulk and nano sizes of the three metallic oxides either singly or in mixtures for 28 days. The basis for the sublethal concentration was that the 96hr acute toxicity of the varied sizes of the three metallic oxides was nontoxic up to the concentrations of 100mg/L with no significant mortality at the highest exposure concentrations. The gills were collected for histopathology. Results. Of the three metal oxide nanoparticles, SiO was the most toxic, with histopathological alteration index (HAI) of 20.0, followed by nano-CuO (HAI, 10.0) and nano-Al2O3 (HAI, 2.0). In single exposure, the gill alterations include high frequencies of erosion of gill lamella (EGL), hypertrophy (HPT), oedema (OD), and necrosis (N). Less damage was observed at the combination of the metal oxide nanoparticles of SiO+Al2O3, SiO+CuO and SiO+Al2O3+CuO in equal (1:1HAI, 2 and 6; 1:1:1HAI, 6) and unequal ratios (1:2HAI, 16 and 6; 2:1HAI, 8 and 6). Similarly, all bulk combinations were also antagonistic except for the equal ratio of bulk CuO (HAI, 20) and bulk Al2O3 (HAI, 10) that gave additive effect with HAI of 32. Conclusion. The joint actions of nano Al2O3 and CuO with SiO produced a low toxic effect, unlike the high toxicity of their single trials; this also indicates that nano Al2O3 and CuO are antagonists. Similarly, among the bulk metal oxides (SiO, Al2O3, and CuO), CuO was the most toxic. Bulk SiO and Al2O3 are antagonistic on the effects of CuO on the fish gill. There is need to properly document the ecological implications of nanoparticles in the aquatic environment.

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IU team pursuing breathtaking advancements in regenerative medicine – Indianapolis Business Journal

§ May 9th, 2020 § Filed under Nanotechnology Journal Comments Off on IU team pursuing breathtaking advancements in regenerative medicine – Indianapolis Business Journal

The Indiana University School of Medicine established itself as a leader in regenerative medicine when it recruited Chandan Sen away from Ohio State University in 2018. (Photo courtesy of the IU School ofMedicine)

A dime-size nanochip developed by a world-renowned researcher who recently relocated to Indianapolis could help transform the practice of medicine. It could also turn Indianapolis into a manufacturing and research hub for radically new disease and trauma treatment techniques.

It all began in August 2018, when Chandan Sen, one of the worlds leading experts in the nascent field of regenerative medicine, moved his lab from Ohio State University to the Indiana University School of Medicine. He brought along a team of about 30 researchers and $10 million in research grants, and now serves, among a myriad of other positions, as director of the newly formed Indiana Center for Regenerative Medicine and Engineering, to which IU pledged $20 million over its first five years.

IU recruited Sen away from Ohio State in part because of its desire not just to promote academic research in his field but also to help develop practical, commercial products and uses for hisbreakthroughs.

A scientist prefers to be in the lab and keep on making more discoveries, said Sen, 53.

But I thought that, unless we participate in the workforce development process and the commercialization process, I dont think that the businesspeople would be ready to do it all by themselves. Because its such a nascentfield.

Its definitely newand its potential sounds like the stuff of science fiction.

Regenerative medicine, as its name hints, seeks to develop methods for replacing or reinvigorating damaged human organs, cells and tissues.

For instance, instead of giving a diabetic a lifetimes worth of insulin injections, some of his skin cells could be altered to produce insulin, curing him. Such techniques might also be used for everything from creating lab-grown replacement organs to, someday, regenerating severed limbs.

Regenerative medicine offers a form of medicine that is neither a pill nor a device, Sen said.

It is a completely new platform, where you dont necessarily depend on any given drug, but are instead modifying bodily functions.

A big, tiny breakthrough

Lambert

Sen and his teams signal contribution to the field is a technique theyve dubbed tissue nanotransfection, or TNT. Put simply, it uses a nanotechnology-based chip infused with a special biological cargo that, when applied to the skin and given a brief electrical charge, can convert run-of-the-mill skin cells into other cell types. Potentially, the technique could be used for everything from regrowing blood vessels in burn-damaged tissue to creating insulin-secreting cells that could cure diabetics.

Obviously, such applications are still down the road a ways. But the technology is far enough along that some products are already making it to marketand investors, entrepreneurs and established companies are sniffing around for opportunities. According to the Alliance for Regenerative Medicine, more than 1,000 clinical trials worldwide are using regenerative medicine technologies.

Thousands of patients are already benefiting from early commercial products, and we expect that number will grow exponentially over the next few years, said Janet Lambert, the alliances CEO.

Lambert predicts that the number of approved gene therapies will double in the next one to two years. Last year, the U.S. Food and Drug Administration predicted it would be approving 10 to 20 cell and gene therapies each year by2025.

Shekhar

These new techniques could do more than just revolutionize medicine. They could also upend the medical industry as we know it. And the IU School of Medicineand Indianapoliscould lead the way.

There are really only two or three places in the country that did the kind of comprehensive work that Dr. Sens group was doing, said Anantha Shekhar, executive associate dean for research at IU School of Medicine. And they were doing it from the lab all the way to the clinic, where they were already applying those technologies in patients.

So it was very attractive to think of starting with a bangbringing a comprehensive group here and creating a new center.

Ambitious goals

Instead of merely treating chronic conditions, regenerative medicine could end them, once and for all.

For instance, consider a car with an oil leak. The traditional medical approach might be to live with the chronic condition by pouring in a fresh quart of oil every few days. The regenerative medicine approach would fix the leak. Its good for the car, good for the cars owner but not necessarily good for the guy who was selling all those quarts of oil.

Which is why these new techniques, if they catch on, could cause turmoil in the medical industry.

Because regenerative medicine has the potential to durably treat the underlying cause of disease, rather than merely ameliorating the symptoms, this technology has the potential of being extremely disruptive to the current practice of medicine, Lambert said.

This has the potential to be hugely disruptive, Sen added, because so much of medicine today relies on huge industrial infrastructures to manage, not cure, chronic diseases and disabilities.

Coy

If such disruption comes to pass, the leaders of 16 Tech, a 50-acre innovation district northwest of downtown that aspires to house dozens of medical-related startups and established firms, would love to be its epicenter.

The Center for Regenerative Medicine will be one of the tenants of 16 Techs first building, a $30million, 120,000-square-foot research and office building scheduled to open in June.

Regenerative medicine is probably one of the next major waves of medical innovation in the world, 16 Tech CEO Bob Coy said. To have him here doing this work gives Indianapolis and Indiana an opportunity to develop an industrial cluster in regenerative medicine.

Coy believes the most momentous early step on that road was the recent establishment by Sen of masters and doctoral programs in regenerative medicine at the IU School of Medicine. Its the first degree of its type in the country, earning IU and Indianapolis the enviable status of first mover.

I think, for example, of [Pittsburghs] Carnegie Mellon University, which, back in the late 1960s, created the first college of computer science in the country, Coy said. And now you know Carnegie Mellons reputation in computerscience.

What isnt in place yet is a state or city program to promote development of a regenerative medicine hub.

We need to start doing that, Coy said. That means putting a lot of the infrastructure in place to support startups that are based on this technology, as well as recruiting companies that want to collaborate with Dr. Sen.

In spite of the lack of a coherent recruitment program, Coys phone has started to ring, thanks largely to Sens presence.

There have been a few meetings Ive had with people who already have relationships with him, who, when they come to town, have reached out to meet and talk about what were doing at 16 Tech, he said.

Fueling entrepreneurship

One of the first 16 Tech startups with designs on the regenerative medicine niche is Sexton Biotechnologies.

The company was groomed by Cook Regentec, a division of Bloomington-based Cook Group charged with incubating and accelerating technologies for regenerative medicine and the related field of cell genetherapy.

Any products that show promise are either folded into the company, turned into their own divisions or, as in Sextons case, spun off as an independent entity with Cook retaining a financial stake.

Werner

Its a measure of the newness of this field that Sextons 17 employees arent working on new medicines, but rather marketing basic tools needed to conduct research. The companys offerings include a vial for storing cell and gene products in liquid nitrogen, and a cell culture growth medium.

Theres a ready market for such tailor-made gear, because, for years, researchers in the regenerative medicine field had to make do with jury-rigged equipment.

What most of those companies did was repurpose things like tools from the blood banking industry, or tools from bio pharma, said Sean Werner, Sextons president.

So thats why a lot of newer companies are starting to build tools explicitly for the industry, as opposed to everybody just having to cobble together stuff that was already out there.

Werner said investors recognize the momentous opportunity in regenerative medicine and are flocking to the field.

Its not something you have to explain, he said. Companies and VC groups are trying to get a piece of it.

What has investors and medical researchers charged up is the almost unlimited range of potential applications, from healing burns to, perhaps someday, regenerating limbs.

I think it would be a huge revolution if were able to, for example, regenerate insulin-secreting cells in children who have become juvenile diabetics or have for whatever reason lost their pancreas, Shekhar said. Those are the kinds of things that will start to change the way we see certain diseases.

Lambert predicted that, as the science advances, so will the business case.

While early programs focused primarily on rare genetic diseases and blood cancers, were already seeing the field expand into more common age-related neurological disorders, such as Parkinsons and Alzheimers, shesaid.

I expect this trend to continue in the coming years, greatly increasing the number of patients poised to benefit from these therapies.

Werner said regenerative medicine also is seeking advancements in manufacturing technologies that will lower the cost of product development.

It all adds up to a huge opportunity the state is well-positioned to seize, Wernerbelieves.

Indiana is a perfect place for this kind of thing to really ramp up, he said. Theres no reason we cant lead thefield.

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Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts – Science Magazine

§ May 9th, 2020 § Filed under Nanotechnology Journal Comments Off on Light-powered CO2 fixation in a chloroplast mimic with natural and synthetic parts – Science Magazine

Hybrid approach catches light

Plant chloroplasts enclose two major photosynthetic processes: light reactions, which generate the energy carriers adenosine triphosphate and reduced nicotinamide dinucleotide phosphate (NADPH), and dark reactions, which use these molecules to fix carbon dioxide and build biomass. Miller et al. appropriated natural components, thylakoid membranes from spinach, for the light reactions and showed that these could be coupled to a synthetic enzymatic cycle that fixes carbon dioxide within water-in-oil droplets. The composition of the droplets could be tuned and optimized and the metabolic activity monitored in real time by NADPH fluorescence (see the Perspective by Gaut and Adamala). These chloroplast-mimicking droplets bring together natural and synthetic components in a small space and are amenable to further functionalization to perform complex biosynthetic tasks.

Science, this issue p. 649; see also p. 587

Nature integrates complex biosynthetic and energy-converting tasks within compartments such as chloroplasts and mitochondria. Chloroplasts convert light into chemical energy, driving carbon dioxide fixation. We used microfluidics to develop a chloroplast mimic by encapsulating and operating photosynthetic membranes in cell-sized droplets. These droplets can be energized by light to power enzymes or enzyme cascades and analyzed for their catalytic properties in multiplex and real time. We demonstrate how these microdroplets can be programmed and controlled by adjusting internal compositions and by using light as an external trigger. We showcase the capability of our platform by integrating the crotonylcoenzyme A (CoA)/ethylmalonyl-CoA/hydroxybutyryl-CoA (CETCH) cycle, a synthetic network for carbon dioxide conversion, to create an artificial photosynthetic system that interfaces the natural and the synthetic biological worlds.

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Healthcare Nanotechnology Market 2020 | Growth Drivers, Challenges, Trends, Market Dynamics and Forecast to 2026 – Cole of Duty

§ May 9th, 2020 § Filed under Nanotechnology Comments Off on Healthcare Nanotechnology Market 2020 | Growth Drivers, Challenges, Trends, Market Dynamics and Forecast to 2026 – Cole of Duty

Endo International

The scope of the Report:

The report analyzes the key opportunities, CAGR, and Y-o-Y growth rates to allow readers to understand all the qualitative and quantitative aspects of the Healthcare Nanotechnology market. A competition analysis is imperative in the Healthcare Nanotechnology market and the competition landscape serves this objective. A wide company overview, financials, recent developments, and long and short-term strategies adopted are par for the course. Various parameters have been taken into account while estimating market size. The revenue generated by the leading industry participants in the sales of Healthcare Nanotechnology across the world has been calculated through primary and secondary research. The Healthcare Nanotechnology Market analysis is provided for the international markets including development trends, competitive landscape analysis, and key regions development status.

By Regions:

* North America (The US, Canada, and Mexico)

* Europe (Germany, France, the UK, and Rest of the World)

* Asia Pacific (China, Japan, India, and Rest of Asia Pacific)

* Latin America (Brazil and Rest of Latin America.)

* Middle East & Africa (Saudi Arabia, the UAE, , South Africa, and Rest of Middle East & Africa)

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Speculations for sales:

The report contains historical revenue and volume that backing information about the market capacity, and it helps to evaluate conjecture numbers for key areas in the Healthcare Nanotechnology market. Additionally, it includes a share of every segment of the Healthcare Nanotechnology market, giving methodical information about types and applications of the market.

Key point summary of the Healthcare Nanotechnology market report:

This report gives a forward-looking prospect of various factors driving or restraining market growth.

It presents an in-depth analysis of changing competition dynamics and puts you ahead of competitors.

It gives a six-year forecast evaluated on the basis of how the market is predicted to grow.

It assists in making informed business decisions by creating a pin-point analysis of market segments and by having complete insights of the Healthcare Nanotechnology market.

This report helps users in comprehending the key product segments and their future.

Strategic Points Covered in TOC:

Chapter 1: Introduction, market driving force product scope, market risk, market overview, and market opportunities of the global Healthcare Nanotechnology market

Chapter 2: Evaluating the leading manufacturers of the global Healthcare Nanotechnology market which consists of its revenue, sales, and price of the products

Chapter 3: Displaying the competitive nature among key manufacturers, with market share, revenue, and sales

Chapter 4: Presenting global Healthcare Nanotechnology market by regions, market share and with revenue and sales for the projected period

Chapter 5, 6, 7, 8 and 9: To evaluate the market by segments, by countries and by manufacturers with revenue share and sales by key countries in these various regions

Finally, the report global Healthcare Nanotechnology market describes Healthcare Nanotechnology industry expansion game plan, the Healthcare Nanotechnology industry knowledge supply, appendix, analysis findings and the conclusion. It includes a through explanation of the cutting-edging technologies and investments being made to upgrade the existing ones.

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Tags: Healthcare Nanotechnology Market Size, Healthcare Nanotechnology Market Trends, Healthcare Nanotechnology Market Growth, Healthcare Nanotechnology Market Forecast, Healthcare Nanotechnology Market Analysis sarkari result, sarkari exam, sarkari naukri

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Healthcare Nanotechnology Market 2020 | Growth Drivers, Challenges, Trends, Market Dynamics and Forecast to 2026 - Cole of Duty

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Latest Innovation On Healthcare Nanotechnology Market With (COVID19) Impact Analysis, Top Companies like Amgen, Teva Pharmaceuticals, Abbott,…

§ May 9th, 2020 § Filed under Nanotechnology Comments Off on Latest Innovation On Healthcare Nanotechnology Market With (COVID19) Impact Analysis, Top Companies like Amgen, Teva Pharmaceuticals, Abbott,…

A Global Research Report called Healthcare Nanotechnology Market was recently published by Market Research Inc. to provide guidance for the business. The report also focuses on global major leading industry players of Global Healthcare Nanotechnology providing information such as company profiles, product picture and specification, price, capacity, cost, production, revenue and contact information. GlobalHealthcare NanotechnologyMarketis expected to develop at a substantial CAGR in the coming years. The most significant factor driving the growth of this market is rising investments inmarket. Investments in theHealthcare Nanotechnology Markethave witnessed huge growth over the past few years.This report also states import and export consumption, supply and demand Figures, cost, price, revenue and gross margins.

Market Research Inc. announced the addition of new informative data titled Healthcare Nanotechnology Market to its extensive repository. The goal of this report is to help readers improve their industrys performance by focusing on important aspects of their business, such as recent developments, technology platforms, and various standard operating procedures and tools. Major competitors around the world have been stressed to understand the level of competition. Several factors, such as productivity, manufacturing base, and product type, were considered to investigate various global regions, such as North America, Latin America, Europe, Asia Pacific, and India. In order to clearly understand the current scope of the existing industry, the competitive environment has been refined.This report also states import and export consumption, supply and demand Figures, cost, price, revenue and gross margins.

Top Key Players: Amgen Teva Pharmaceuticals Abbott UCB Roche Celgene Sanofi Merck & Co Biogen Stryker Gilead Sciences Pfizer

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In addition to corporate strategy, Healthcare Nanotechnology the market throws light on different properties to curb the progress of fuel or industry. The focus is more on applicable sales strategies to increase the companys productivity to achieve higher economic performance. It also covers research and development activities, online and offline activities, the latest product launches, and some of the competitive expansion adopted by major global companies. Research reports use effective graphical presentation techniques such as tables, charts, graphs, diagrams, and info graphics.

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Finally, all aspects of the Healthcare Nanotechnology Market are quantitatively as well qualitatively assessed to study the Global as well as regional market comparatively. This market study presents critical information and factual data about the market providing an overall statistical study of this market on the basis of market drivers, limitations and its future prospects. The report supplies the international economic competition with the assistance of Porters Five Forces Analysis and SWOT Analysis.

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Latest Innovation On Healthcare Nanotechnology Market With (COVID19) Impact Analysis, Top Companies like Amgen, Teva Pharmaceuticals, Abbott,...

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A brief overview of all the Covid-19 vaccines in the pipeline – Quartz

§ May 9th, 2020 § Filed under Genetically Modified Humans Comments Off on A brief overview of all the Covid-19 vaccines in the pipeline – Quartz

Right now, the best bridge to a new normal is a successful vaccine against Covid-19. Scientists are racing to develop one on an unprecedented timeline, but it could still take a year to 18 monthspossibly longer.

Vaccines are harder to make than ordinary pharmaceuticals. Typical drugs carry out a specific process in the body, and they only have to work only until the kidneys and liver filter them out. Vaccines, though, have to do a bit of biological catfishing: They dupe certain cells in our blood, called B-cells, into responding to a pathogenic threat that doesnt actually exist.

Tricking those cells into producing antibodies against a disease it hasnt yet faced is a difficult process. Scientists need help from benign viruses and bacteria, gene editing tools, and even copies of the infectious pathogen itselfand sometimes combinations of all three. And right now, scientists are throwing all of these strategies at Covid-19 to see what sticks.

At the time of writing, there are 123 vaccine candidates in various stages in the research pipeline. In a best-case scenario, multiple kinds of vaccines would be found safe and effective, so there would be several options for drug manufacturers and distributers to make and ship across the globe. Heres your guide to understanding the different approaches.

The most effective way (pdf) to generate antibodies against an infection is to actually get sick. The next best option? Show your B-cells a copy of the same pathogenbut genetically modified or kneecapped with a chemical like formaldehyde so it cant cause an infection. These vaccines cancause a minor infection if the virus is merely weakened and still capable of replicating, but its not nearly as dangerous as if it were at full-strength.

Scientists have developed inactivated or weakened vaccines for illnesses like measles, chicken pox, and polio. These vaccines are tried and true, but finding a new one requires a delicate balance: It has to be as close to the actual virus as possible, but not capable of replicating like it normally would.

If for some reason, the virus does start replicating, a perfectly healthy person would become sick. This is why safety testing is so critical for these vaccines. Currently, only two vaccine candidates in this category are in early clinical trials: one being developed by the Wuhan Institute of Biological Products, and one by Sinovac Biotech, which is also based in China.

Instead of showing B-cells the entire pathogen, protein subunit vaccines only show the body partsof the virus. For Covid-19, most developers are going after the spike protein that SARS-CoV-2 uses to enter our cells. The hope is that by showing B-cells that characteristic protein, theyll be able to recognize it on the pathogen itself, too. Itd be like showing your B-cells a novelty bedazzled bowling hat, and telling them to watch out for any invader wearing it in the future.

Protein subunits arent able to turn into a full-blown infection. But the immune responses they produce get weaker over time, which means that a person may require boosters throughout their life. Some annual flu vaccines take the form of protein subunits, as does the HPV vaccine. So far, none of the protein subunit vaccines have made it to testing in humans.

Protein subunit vaccines require manufacturers to genetically modify a microbe, like the bacteria E. coli, to produce the desired protein. Then these proteins have to be purified and mixed with adjuvants, which signal to B-cells to pay attention to them. So to speed up the process, scientists have worked out a way to get the body to produce these desired subunit proteins themselves.

Nucleic acid vaccines use either double-stranded DNA (the same genetic material stored in each of our cells nuclei), or messenger RNA (mRNA). These forms of genetic material contain the recipe for the desired proteins, just like our DNA does (mRNA is genetic material that is just a little farther along in the process). Cells within the body translate this foreign genetic material into target proteins, which B-cells then create antibodies against.

The advantage of this approach is that its relatively fast; once scientists have genetically sequenced a novel pathogen, they can isolate target proteins for the body to recreate. The challenge, though, is getting the body to actually respond to them.

Nucleic acid vaccines made with DNA have to get through the cell membrane and the cells nucleic membrane, which protects your DNA.Those with mRNA only have to get through the cell membrane, but theres still an additional hurdle: Even if the cells make the desired protein, they have to fold it into a shape that resembles the actual viral protein. Its like the difference between using a boxed cake mix to make 12 cupcakes versus two round cakes.

A nucleic acid vaccine has never been approved for use. But one of the leading vaccine candidates for Covid-19 uses this approach. Its an mRNA vaccine created by the Cambridge-based company Moderna, and the US government has already invested millions in it, even though its still in early clinical testing.

Another way to get around B-cells failure to respond to subunit vaccines or nucleic acid vaccinesis to try a hybrid approach: using otherweakened or inoculated viruses to transport genetic material that codes for bits of SARS-CoV-2, the coronavirus that causes Covid-19. The carrier virus can make its way into our cells like other infectious diseases wouldbut once it gets there, it produces SARS-CoV-2 proteins that generate the correct antibody response.

Some of these carrier viruses, called viral vectors, are capable of reproducing to a small degree, while others dont at all. Either way, they shouldnt cause an actual illness. The only reason these vaccines would be ineffective is if the recipient already has some form of immunity against the knocked-out vectormaking it impossible for the virus to enter our cells. One virus that scientists like to use is an adenovirus, for example, which often causes the common cold.

The newly-minted Ebola vaccine, which the US Food and Drug Administration approved in December 2019, is a viral vector vaccine. There are two promising vaccine approaches for Covid-19 using this platform, one by researchers at Oxford University, and one from the drug company Johnson and Johnson.

The last main tactic that developers are exploring is another variation of subunit vaccines. Instead of getting B-cells to recognize only certain viral proteins, virus-like particle vaccines introduce all the proteins on the outer shell of SARS-CoV-2. Its like showing B-cells only the menacing trench coat of a potential pathogen. Underneath the trench coat, though, theres nothingno genetic machinery to reproduce and destroy cells.

Currently, there are no virus-like particle vaccines in human trialsbut Medicago Inc., a company based in Quebec City in Canada, is hoping to start theirs in July.

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A brief overview of all the Covid-19 vaccines in the pipeline - Quartz

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Wuhan market had a role to play in coronavirus outbreak, more research required: WHO – BusinessLine

§ May 9th, 2020 § Filed under Genetically Modified Humans Comments Off on Wuhan market had a role to play in coronavirus outbreak, more research required: WHO – BusinessLine

The World Health Organization on Friday said that a wholesale market in Wuhan, China had played a role in the outbreak of the novel coronavirus in 2019, calling for more research, Reuters reported.

Dr Peter Ben Embarek, a WHO expert on food safety and zoonotic viruses that cross the species barrier from animals to humans said that the market had a role to play in the coronavirus outbreak.

However, whether it was a source or a possibly amplifying setting for the outbreak is yet to be determined. Embarek called for more research as it was not clear whether it was just a coincidence that more cases were detected around the market or if animals or infected vendors or shoppers had brought the virus into the market, the report said.

Recently, the United States President Donald Trump and US Secretary Mike Pompeo have voiced their criticism of China alleging that the virus had originated in a lab in Wuhan.

The claims of the virus being man-made have been refuted by the WHO as well as the US intelligence community who believe that according to the evidence so far, the virus seems to have originated in nature rather than being genetically modified or manmade.

Embarek further said that the most important aspect of understanding how the virus evolved and how it adapted to humans was to get hold of the virus before it adapted to humans.

China probably had the expertise needed to conduct the investigations, he further said.

China had shut its Wuhan wet market in January owing to the surging number of Covid-19 cases putting a temporary ban on the trade of wildlife meat.

Embarek said that markets across the globe selling such meat should be regulated. Last month, Elizabeth Maruma Mrema, Executive Secretary of the United Nations Convention on Biological Diversity had called for a global ban on wildlife markets, The Guardian reported.

The UN biodiversity chief urged countries to ban such markets in a bid to curb future pandemics.

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Wuhan market had a role to play in coronavirus outbreak, more research required: WHO - BusinessLine

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