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Nano Therapy Market Projected to Show Strong Growth | Key Players: Parvus Therapeutics, Nanoprobes, Nanospectra Biosciences – The Market Journal

§ February 26th, 2020 § Filed under Nano Medicine Comments Off on Nano Therapy Market Projected to Show Strong Growth | Key Players: Parvus Therapeutics, Nanoprobes, Nanospectra Biosciences – The Market Journal

Latest Study on Industrial Growth ofGlobal Nano Therapy Market2019-2025. A detailed study accumulated to offerLatest insights about acute features of the Nano Therapy market. The report contains different market predictions related to market size, revenue, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing the key driving and restraining forces for this market, the report also offers a complete study of the future trends and developments of the market. It also examines the role of the leading market players involved in the industry including their corporate overview, financial summary and SWOT analysis.

The Major Players Covered in this Report: Nanoprobes, Nanospectra Biosciences, Parvus Therapeutics, Smith And Nephew, Selecta Biosciences, Sirnaomics, Tarveda Therapeutics & Sirnaomics

Nano Therapy Market Study guarantees you to remain / stay advised higher than your competition. With Structured tables and figures examining the Nano Therapy, the research document provides you a leading product, submarkets, revenue size and forecast to 2025. Comparatively is also classifies emerging as well as leaders in the industry.

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This study also covers company profiling, specifications and product picture, sales, market share and contact information of various regional, international and local vendors of Global Nano Therapy Market. The market opposition is frequently developing greater with the rise in scientific innovation and M&A activities in the industry. Additionally, many local and regional vendors are offering specific application products for varied end-users. The new merchant applicants in the market are finding it hard to compete with the international vendors based on reliability, quality and modernism in technology.

Nanotherapy is a branch of nanomedicine that involves using nanoparticles to deliver a drug to a given target location in the body so as to treat the disease through a process known as targeting.Much of the research in nanotherapy has been largely directed towards cancer therapy. One of the biggest issues with conventional methods is that as the drug product is distributed throughout the body, both healthy and unhealthy (cancerous cells) are affected, which in turn affects the effectiveness of cancer treatment. It is for this very reason that most cancer patients tend to be hesitant when it comes to chemotherapy. However, nanotherapy, which is also referred to as targeted therapy, offers to deliver the molecules to the affected cells in order to help treat the disease without causing other negative effects to the healthy cells.In 2017, the global Nano Therapy market size was xx million US$ and it is expected to reach xx million US$ by the end of 2025, with a CAGR of xx% during 2018-2025.

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The titled segments and sub-section of the market are illuminated below:

In-depth analysis of Global Nano Therapy market segments by Types: , Nanomaterial And Biological Device, Nano Electronic Biosensor, Molecular Nanotechnology & Implantable Cardioverter-Defibrillators

In-depth analysis of Global Nano Therapy market segments by Applications: Cardiovascular Disease, Cancer Therapy, Diabetes Treatment & Rheumatoid Arthritis

Major Key Players of the Market: Nanoprobes, Nanospectra Biosciences, Parvus Therapeutics, Smith And Nephew, Selecta Biosciences, Sirnaomics, Tarveda Therapeutics & Sirnaomics

Regional Analysis for Global Nano Therapy Market:North America (United States, Canada and Mexico)Europe (Germany, France, UK, Russia and Italy)Asia-Pacific (China, Japan, Korea, India and Southeast Asia)South America (Brazil, Argentina, Colombia etc.)Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

Furthermore, the years considered for the study are as follows:Historical year 2013-2017Base year 2018Forecast period** 2018 to 2023 [** unless otherwise stated]

**Moreover, it will also include the opportunities available in micro markets for stakeholders to invest, detailed analysis of competitive landscape and product services of key players.

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Guidance of the Global Nano Therapy market report:

Detailed considerate of Nano Therapy market-particular drivers, Trends, constraints, Restraints, Opportunities and major micro markets. Comprehensive valuation of all prospects and threat in the Global Nano Therapy market. In depth study of industry strategies for growth of the Nano Therapy market-leading players. Nano Therapy market latest innovations and major procedures. Favorable dip inside Vigorous high-tech and market latest trends remarkable the Market. Conclusive study about the growth conspiracy of Nano Therapy market for forthcoming years.

What to Expect from this Report On Nano Therapy Market:

1. A comprehensive summary of several area distributions and the summary types of popular products in the Nano Therapy Market.2. You can fix up the growing databases for your industry when you have info on the cost of the production, cost of the products, and cost of the production for the next future years.3. Thorough Evaluation the break-in for new companies who want to enter the Nano Therapy Market.4. Exactly how do the most important companies and mid-level companies make income within the Market?5. Complete research on the overall development within the Nano Therapy Market that helps you elect the product launch and overhaul growths.

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Detailed TOC of Nano Therapy Market Research Report-

Nano Therapy Introduction and Market Overview Nano Therapy Market, by Application [Cardiovascular Disease, Cancer Therapy, Diabetes Treatment & Rheumatoid Arthritis]

Nano Therapy Industry Chain Analysis Nano Therapy Market, by Type [, Nanomaterial And Biological Device, Nano Electronic Biosensor, Molecular Nanotechnology & Implantable Cardioverter-Defibrillators]

Industry Manufacture, Consumption, Export, Import by Regions (2013-2018) Industry Value ($) by Region (2013-2018)

Nano Therapy Market Status and SWOT Analysis by Regions

Major Region of Nano Therapy Marketi) Global Nano Therapy Salesii) Global Nano Therapy Revenue & market share Major Companies List Conclusion

Thanks for reading this article; you can also get individual chapter wise section or region wise report version like North America, Europe or Asia.

About Author:HTF Market Report is a wholly owned brand of HTF market Intelligence Consulting Private Limited. HTF Market Report global research and market intelligence consulting organization is uniquely positioned to not only identify growth opportunities but to also empower and inspire you to create visionary growth strategies for futures, enabled by our extraordinary depth and breadth of thought leadership, research, tools, events and experience that assist you for making goals into a reality. Our understanding of the interplay between industry convergence, Mega Trends, technologies and market trends provides our clients with new business models and expansion opportunities. We are focused on identifying the Accurate Forecast in every industry we cover so our clients can reap the benefits of being early market entrants and can accomplish their Goals & Objectives.

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Nano Therapy Market Projected to Show Strong Growth | Key Players: Parvus Therapeutics, Nanoprobes, Nanospectra Biosciences - The Market Journal

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Using Medications – Microscopic Colitis Foundation

§ February 26th, 2020 § Filed under Nano Medicine Comments Off on Using Medications – Microscopic Colitis Foundation

may be effective at reducing, or even stopping diarrhea in some cases, in other cases they sometimes cause an increase in bloating and pain. Therefore patients using this treatment should pay attention to what their body is telling them, because the treatment is not helpful for everyone who has MC. And of course treatments in this category do not address the underlying cause of the inflammation that leads to the development and perpetuation ofd MC and bile acid malabsorption. They only treat the symptom of bile acid malabsorption.


Many antidepressants have a side effect of constipation, and this is the reason why various antidepressants are sometimes prescribed to treat MC. The most popular choices for this use seem to be the selective serotonin reuptake inhibitors (SSRIs) and the serotonin-norepinephrine reuptake inhibitors (SNRIs). Because depression seems to be commonly associated with this disease anyway, in some cases anti-depressants may provide additional benefits (provided that they are successful in providing some degree of depression relief).

It's also possible that the anti-anxiety attributes of some of these medications may also provide some benefits for reducing muscular contractions in the gut. Obviously this class of drugs does nothing to suppress the inflammation that leads to the development of MC in the first place, but for some people, stopping the diarrhea provides sufficient symptomatic relief that they consider the treatment to be a success. Whether ignoring the inflammation is a prudent choice, is a topic that is open to debate.

Not surprisingly, for many patients these drugs do not resolve the diarrhea. And for other patients, they may even cause the existing symptoms to become worse. The relatively high risk of side effects, and the risk that the body may develop a dependency on these drugs with long-term use, requiring the dosage to be tapered when their use is to be discontinued, further complicates prescribing these drugs to treat MC.

While an antidepressant might help to relieve diarrhea in some cases where diarrhea is the predominant gastrointestinal symptom of MC, this class of drugs would obviously be contraindicated in cases where constipation is the predominant GI symptom, or where alternating diarrhea and constipation is the rule. And of course SSRIs and SNRIs would also be contraindicated in any case where the patient is sensitive to the drug, as indicated by an adverse reaction of any type. As mentioned at the beginning of this discussion, this class of drugs has been associated with causing MC in a significant number of cases, so they should be used with caution and discontinued if the patient's symptoms become worse.

That said, in certain cases of MC where intestinal motility is too slow, some patients have found that a very low dose of amitriptyline (10 mg per day) seems to help regulate gut motility and may help to establish and maintain remission during the recovery process. This illustrates how different the response to certain drugs can be in different cases.


Because NSAIDs are contraindicated for MC patients, the only non-narcotic painkiller known to be safe for use by someone with MC appears to be Tylenol (acetaminophen). Unlike most narcotic painkillers however, Ultram (tramadol) typically does not cause patients to build up a tolerance after extended use, so it has a very low risk of addiction compared with most of the other narcotic painkillers, such as oxycodone or hydrocodone. That said, please keep in mind that a few patients have discovered that they are exceptions to this rule, and tramadol seems to cause addictive issues for them.

Narcotic painkillers are sometimes prescribed to treat MC, not only for their analgesic effect, but because they slow down motility and tend to cause constipation. Therefore please keep in mind that in addition to the risk of addiction, the use of narcotic type painkillers to treat MC carries a risk of possibly causing a life-threatening fecal impaction problem. And as is the case with many medications, using narcotic-based painkillers to treat MC amounts to only treating the symptoms, while ignoring the inflammation that causes the disease.5-aminosalicylic acid (5-ASA)

As mentioned earlier in this discussion, the drugs most often prescribed for treating microscopic colitis tend to be those that have been shown to be effective for treating the other inflammatory bowel diseases. In the early days, sulfasalazine (Azulfidine), was often prescribed to treat MC.

Sulfasalazine is a prodrug. That is to say, sulfasalazine does not become active in the digestive system until it is broken down by bacteria in the colon into 5-aminosalicylic acid (5-ASA) and sulfapyridine. Sulfapyradine is known to have a therapeutic effect for rheumatoid arthritis. However, no beneficial effect from sulfapyradine has been described for treating inflammatory bowel disease. Since many people tend to react adversely to sulfa drugs, these days sulfasalazine has mostly been replaced with mesalamine, sometimes referred to as mesalazine, for the treatment of IBDs.

Mesalamine contains the active moiety of sulfasalazine, known as 5-aminosalicyclic acid. There are a number of drugs in this group that use the same active ingredient, and they are sometimes referred to as 5-ASA drugs. In the United States, this group of drugs includes a number of popular brands, including Asacol, Asacol HD, Lialda, Apriso, Colazal, Pentasa, and Rowasa. In the United Kingdom, the brand names commonly available include Asacol, Canasa, Ipocal, Salofalk, and Mezavant XL.

Other brands are available in other countries, but they are all based on mesalamine as the active ingredient. They all use some form of enteric coating to prevent the medication from becoming activated before it reaches the targeted area of the digestive tract, which is usually somewhere in the vicinity of the lower third of the small intestine (the ileum), and the colon. Unfortunately, mesalamine is chemically related to aspirin, so people who are allergic to aspirin, or other salicylates, should not use this medication.

And there is also a risk that this chemical similarity may extend to other attributes of NSAIDs. Even though in vitro studies have shown that mesalamine apparently inhibits the enzymes believed to be responsible for the production of both leukotrienes and prostaglandins (both known to be inflammatory mediators), case studies show that in certain individuals, and in conjunction with inflammatory bowel disease, mesalamine may promote the production of leukotrienes, similar to NSAIDs, resulting in diarrhea or intestinal inflammation, or both. That implies that the 5-ASA drugs may benefit some patients with MC, while causing the inflammation to become worse in other cases.

Experience shows that in general, the medications in this group are relatively effective at suppressing the inflammation that is associated with MC, but they tend to be somewhat slow to bring remission. Typically, they require several weeks or longer, before control is established. They dont always successfully control the symptoms and some patients cannot tolerate them.


Another type of medication commonly prescribed to treat microscopic colitis is the corticosteroids. Corticosteroids are well known for suppressing inflammation, and this class of drugs is generally more effective for most patients than the 5-ASA medications in bringing remission of symptoms. Unfortunately though, some of the corticosteroids have earned a reputation for causing Draconian side effects, if taken on a long-term basis.

One of the corticosteroids that was traditionally prescribed in years past, is prednisone, and some gastroenterologists still prescribe it to treat MC. However, due to its rather significant risk of somewhat serious side effects, it cannot be used for long-term treatment without incurring an unacceptably high risk of adverse health effects. Its primary advantages are low cost and potent efficacy. Part of its effectiveness is due to its immunosuppressive effect. Of course this immunosuppressive effect also has the not insignificant disadvantage of lowering the bodys resistance to disease and infections. And because of its powerful effect on the bodys adrenals, withdrawal from the drug must be carefully managed by means of slowly decreasing the dosage, during the withdrawal period. It has also been documented by research that another disadvantage of using prednisone and other corticosteroids is that they interfere with wound healing, resulting in longer times required for healing, and a possible increase in the risk of infection.

A more modern corticosteroid, budesonide, can often be used just as effectively as prednisone, and it carries a much lower risk of causing adverse health effects. Budesonide is the active ingredient in Entocort EC. Entocort EC capsules offer the advantage of a special enteric coating that delays the activation of the budesonide until it reaches the lower third of the small intestine and the colon, so that only a minimal amount of the active ingredient is absorbed into the bloodstream. Clinical trials show that when budesonide is administered in this way, only nine to 21 % of it is absorbed into the bloodstream. The relatively low rate of absorption into the bloodstream tends to significantly diminish the risk of systemic side effects. That means that the lions share of the medication is available to treat the inflamed areas of the ileum and the colon, and that makes Entocort EC an effective, yet much safer medication to use, compared with prednisone.

Arguably the biggest advantage that Entocort EC has over the other corticosteroids for treating MC is that it has been shown to be safe for long-term use. Clinical trials lasting for 52 weeks have demonstrated that the risk of side effects for long-term use of Entocort EC at six mg per day is similar to the risk associated with short-term use (eight weeks) of Entocort EC at nine mg per day, thus establishing its safety for long-term use at six mg per day.

An even newer medication based on budesonide is available. It's called Uceris, and it's manufacturer claims that due to the fact that it does not become activated until it is well down in the colon, there is no risk of any systemic effect at all, and therefore no tapered withdrawal regimen is required with this particular corticosteroid. Uceris is labeled for ulcerative colitis, and UC typically begins at the rectal end of the digestive tract and spreads upward, thus the reason for the manufacturer designing the drug to become active so far down in the digestive tract. While this is ideal for treating UC, Uceris might not be as effective for treating MC in some cases, due to the fact that MC typically affects random areas scattered over the entire colon, and more often than not the terminal ileum is also inflamed. However, reports from MC patients who have used Uceris have been generally favorable.Immune system suppressants

A few GI specialists have been known to prescribe certain powerful immune system suppressants such as Imuran (azathioprine) or methotrexate to treat MC. These immune system suppressants were originally developed to help reduce rejection rates after organ transplants and for chemotherapy connected with cancer treatments, but they are often prescribed to treat Crohns disease.

Azathioprine is another prodrug. During the digestive process, it is metabolized into the active form, 6-mercaptopurine, which impedes DNA synthesis. This in turn retards the propagation of new cells, especially lymphocytes. Normally, lymphocytes tend to grow rapidly. T cells and B cells are particularly affected by this growth restriction. It is generally thought that excessive numbers of T-cells are primarily responsible for the inflammation associated with MC (and other autoimmune issues). Because of the ability of Azathioprine to suppress the propagation of T-cells, it is effective for treating certain autoimmune diseases and it's commonly used to treat Crohns disease, thus establishing its potential effectiveness for treating MC.

Methotrexate is used in the treatment of cancer, autoimmune diseases such as rheumatoid arthritis, psoriasis, and psoriatic arthritis. It has even been used to induce medical abortions. It works by inhibiting the metabolism of folic acid. It was originally developed as a chemotherapy treatment and it is known to be effective against a number of different types of cancers. At present however, unlike azathioprine, it appears that methotrexate is rarely prescribed to treat microscopic colitis.

In general, since immune system suppressants carry an elevated risk of developing an infection or cancer, this class of drugs should only be considered if all other less risky treatments have been tried and failed to provide relief of symptoms.

Anti-TNF medications

The anti-tumor necrosis factor medications (anti-TNF) such as Embrel (Etanercept), Remicade (Infliximab), and Humira (Adalimumab) are increasingly being prescribed for treating various inflammatory issues, including Crohns disease. Because of that, some doctors view them as a possible option for treating microscopic colitis. This class of drugs is a relatively recent development however, and case studies show that while most patients with inflammatory issues may show benefits, a very small percentage of patients experience severe, and even life-threatening adverse events.

The anti-TNF drugs, for example, have recently been linked with an increased risk of a possibly fatal infection with legionella and listeria bacteria, in addition to the long list of pathogens that were previously listed. While they are deemed to be generally safe for most patients, careful consideration should be given before using one of these drugs, because they work by suppressing the immune system, and that can lead to a significantly increased risk of infections and other adverse events.

Surgical Intervention

As a last resort treatment, some gastroenterologists may even recommend an ileostomy in certain severe cases of MC where the patient does not respond to conventional medical treatment methods. An ileostomy diverts the fecal stream into an external pouch, totally bypassing the colon, and thus preempting any opportunity for colonic inflammation, by isolating the colon from the fecal stream. Published case studies show that this surgical procedure will usually bring remission from symptoms. But using such a radical treatment method seems not unlike burning down the barn in order to get rid of the rats, since the colon will no longer provide any functional benefits to the body after the procedure. And if the small intestine is involved in the reactions (and this appears to be the case for many patients), then an ileostomy could not be expected to resolve the reactions that originate in the small intestine.

But the claims that this procedure will always bring remission, are simply not true. There are cases where an ileostomy will not resolve MC symptoms.

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Microscopic Colitis and Diet: Dos and Donts

§ February 26th, 2020 § Filed under Nano Medicine Comments Off on Microscopic Colitis and Diet: Dos and Donts

Microscopic colitis refers to inflammation in the colon. There are two main types: collagenous and lymphocytic. If you have collagenous colitis, it means that a thick layer of collagen has formed on colon tissue. If you have lymphocytic colitis, it means lymphocytes have formed on colon tissue.

This condition is called microscopic because doctors must look at tissue under a microscope to diagnose it. This condition usually causes watery diarrhea and other digestive symptoms.

Dealing with watery diarrhea, abdominal cramping, nausea, and fecal incontinence can be a challenge to manage. If you have microscopic colitis, these symptoms may have become part of your everyday life. And you may be searching for ways to ease your symptoms without the use of drugs.

Can eating or avoiding certain foods help? Read on to find out more about microscopic colitis and your diet.

Microscopic colitis sometimes gets better on its own. If your symptoms continue without improvement or if they worsen, your doctor may recommend dietary changes before moving on to medications and other treatments.

Ingredients that may irritate the colon include:

Beyond specific foods, staying hydrated is another part of your dietary needs. Keeping hydrated may have a big effect on how you feel.

Diarrhea dehydrates the body, so drinking plenty of fluids can help replenish your body and help foods move through the digestive tract more efficiently.

Soft foods that are easy to digest are usually the best choices for everyday eating. Options include:

Also, it isnt just what you eat. How you eat can also have a big effect. Large meals might cause more bouts of diarrhea. Eating smaller meals throughout the day may help reduce this.

You should also stay hydrated. In addition to drinking water, you may also want to include:

Daily probiotic intake from a concentrated, well-tested product like VSL#3 is recommended. A multivitamin and mineral-rich diet is also beneficial for people with chronic diarrhea and nutrient malabsorption.

Foods that are high in fiber, gluten, or lactose may make your symptoms worse. These include:

Foods that are particularly spicy, fatty, or fried may also upset your digestive track even more.

You should limit or avoid beverages containing caffeine. These include:

Feeling overwhelmed? Consider setting up an appointment with a dietitian who can help guide your food choices and suggest meal planning tips.

You may also consider keeping a food diary to help you keep track of what symptoms accompany which foods. This can help you determine which foods trigger your symptoms.

If changing your diet or discontinuing medications doesnt ease your symptoms, you should make an appointment with your doctor. There are other treatments available that may ease your symptoms. These include:

In severe cases, your doctor may suggest surgery to remove a portion of your colon.

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Horses lose four of their toes in the womb – Massive Science

§ February 26th, 2020 § Filed under Nano Medicine Comments Off on Horses lose four of their toes in the womb – Massive Science

For many, the Super Bowl came and went. But for the multitude who witnessed their team win its first championship in over 50 years, the celebrations all around Kansas City could be detected by radar.

A tweet from the National Weather Service of Kansas City, which quickly went viral with over 3.2k retweets, shows Kansas City roaring in celebration after the win of their beloved Chiefs.

I talked with Andy Bailey, Warning Coordination Meteorologist for NWS Kansas City/Pleasant Hill, who explained the system.

Radar "works by transmitting a very short pulse of high power, microwave energy. After this transmission, it goes into a listening mode, waiting for the energy to go out, hit something, and be returned to the radar."

"While the pulses transmitted are several hundred thousand watts the amount returned to the radar is much smaller, just a fraction of one watt."

So what did the radar actually pick up? Bailey said the radar picked up "an increase in returned energy to the radar immediately after the Chief's victory."

Because of the type of radar used (called a dual-pol radar), the National Weather Service was also able to pick up shapes: "We can't see individual things like a single bird, plane, or raindrop, but we can see the predominant type of particles in a given volume of the atmosphere."

"Using this dual-pol technology, we could tell it wasn't precipitation, or biological (birds). The only other logical thing it could have been was fireworks debris given that no matter where in the city you were at the conclusion of the game, you were within earshot of exploding fireworks."

While radar works by sending out short bursts of electromagnetic waves which then reflect back to the radar when it hits particlesin the atmosphere, this specialized dual-pol radar is much more accurate because it creates a two-dimensional picture - both horizontal and vertical.

According to Bailey, this is the same tech that helps save lives: "Incidentally, this is the same technique we use to look for tornadic debris during severe weather episodes."

After the EF4 tornadoes that hit the Kansas City area last year, the public's trust in the National Weather Service saved lives, "our social media messages were seen around 5 million times on facebook and twitter during and immediately after that tornado event. Most importantly, people heeded our warnings and nobody was killed"

So while you were celebrating (or still celebrating, we don't judge!), the National Weather Service is keeping you safe. In fact, for meteorologist Andy Bailey, the whole purpose of sharing the tweet boils down to trust: "In our business, trust saves lives. So when the entire city is electric and celebrating a Chiefs Super Bowl victory, and we can sense that on radar, we're going to communicate that."

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Horses lose four of their toes in the womb - Massive Science

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Urine facials and other bizarre beauty treatments not for the faint of heart – TimesLIVE

§ February 26th, 2020 § Filed under Nano Medicine Comments Off on Urine facials and other bizarre beauty treatments not for the faint of heart – TimesLIVE

While ageing is inevitable, its becoming less acceptable to actually let it show. These days, those in the know (and in the money) arent just freshening up with a little sting from the plastic surgeons needle. Theyre also doing a slew of other stuff (rather scary sounding, I might add), in the frantic hope of looking 21 again.

Botox is just the tip of the iceberg: from forever-young LA to always-on-trend London, prepare to be astounded by some of the newest global beauty treatments that promise drastic results as long as youre not squeamish.

A trend that is going viral not just enhancing natural shape but actually changing it altogether is Russias Devil Lips.

Forget anti-ageing, this procedure is about looking downright weird. It involves injecting dermal filler to produce waves in the lip and its vermilion border, explains Dr Alek Nikolic, a medical practitioner with a special interest in aesthetic medicine and skincare ingredients.

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The race to replace the hypodermic needle – Fast Company

§ February 25th, 2020 § Filed under Nano Medicine Comments Off on The race to replace the hypodermic needle – Fast Company

New research out of Rutgers University proposes a needle thats far more humaneand its inspired by some of the shrewdest animals in nature. Its a patch full of microscopic needles dubbed microneedles. Place it onto your skin, and it pokes into your arm. The needles are barbed, like the stinger of a honeybee or the hooking appendages of a parasite. So once they pierce the skin, they can anchor in to stay put for as long as the test or task requires. And since the needles are hollow, they can deliver drugs or take blood, just like larger needles, without causing any pain.

The needles were produced through a process the researchers call 4D printing. Basically, the needles are 3D-printed with polymers, but the core structure is a programmable material that reshapes itself, like a piece of self-folding origami, after the printing process is over (MIT has experimented with this approach to materials quite a bit in the past). Its this folding that creates the rounded hooks. The microneedles can stay affixed within ones skin 18 times better than any previously researched microneedle, which makes them more reliable for drug delivery, and opens the possibility that a patch could track antibodies, changes in your DNA, or all sorts of other things we might want to sense in our biology. In testing, the researchers showed the patch was able to deliver drugs over the course of a full, 24-hour day.

So will these needles take over medicine? Professor Howon Lee, who led the research, has filed a patent on his technology but cannot speak to how long it would take to be commercialized. But his work is part of a larger push to revolutionize hypodermic needle with microneedles, thanks to technology and design coming together to prove an age-old ideaa revolution Lee believes is coming in perhaps [the] next decade.

Before the 1990s, when microneedle research began in earnest, scientists had hypothesized for decades that microscopic needles would one day take blood or deliver drugs without pain. Thirty years ago, these theories suddenly became plausible, thanks to the rise of microchip manufacturing, when working with materials and structures at the nanometer level became a real possibility.

Today, there are countless transdermal patches on the market that are used to deliver various drugs and herbs through your skin, but most are designed without needles, with chemicals that simply seep into your body (this is less efficient and reliable than microneedles). 3M has two patches in early testing that can deliver drugs and vaccines. Other companies are working on simpler microneedle patches that make tiny holes in your arm without delivering medicine on their own, meaning you stick the patch on and immediately pull it offthen you cover the prepped skin with a traditional skin patch to deliver the medicine more efficiently. Other research is looking at how microneedles could work better across the board, so you have ideas like the barbed approach detailed above, or a system developed last year, which uses magnesium to actively burst microneedle payloads into your skin, powered by hydrogen bubbles. All of these alternatives are in various states of development, but they point to a significant shift in the experience of getting a shot.

Alternatives to the scary hypodermic needle are just beginning to come to fruition, and theyre getting better at a rapid pace. Now if the world of science could just do something about peoples irrational fear of vaccines, wed really have something.

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Differences in How Cardio and Strength Affect Your Health – msnNOW

§ February 25th, 2020 § Filed under Nano Medicine Comments Off on Differences in How Cardio and Strength Affect Your Health – msnNOW

(Getty Images) Young sporty hispanic woman running on treadmill and doing workout at fitness health club

The fitness world loves the debate: cardio or strength training? Which workout is best, and which can you cut from your exercise routine? The reality is cardio and strength don't need to be mutually exclusive nor should they be.

"Both (cardio and strength training) need to be included in a well-rounded exercise program," says Michael Rebold, certified strength and conditioning specialist and director of integrative exercise sciences at Hiram College in Ohio. That's true whether you are vying for improved body composition, heart health or longevity.

"They complement each other," says Dr. Daniel V. Vigil, a family medicine and sports medicine physician with UCLA Health in California. "Many of our acts of daily living rely on having efficient cardiorespiratory and musculoskeletal systems." For example, walking the dog, playing with the kids or running to catch the bus rely predominantly on aerobic fitness, while getting up off of the floor, carrying groceries and performing home repairs rely more so on muscular fitness. Perhaps surprisingly, that's also true of activity such as taking the stairs. Strength plays a bigger role than cardio in determining if you can make it up a flight of stairs without getting winded.

For most people, how much time you should devote to cardiovascular forms of exercise versus resistance training depends on what you enjoy most. "The best exercise, from a public health perspective, is the one that you actually like and will do," Vigil says. That said, the right workout for you also depends on your individual health and fitness goals.

Below, experts share the unique benefits of cardiovascular exercise and strength training and how to get the best of both workouts.

Body fat levels. Exercise of all kinds reduces body fat levels by expending energy. That includes cardiovascular exercise as well as weight training. Intensity is the most important determiner of how many calories you burn during a workout, says Dani Singer, a certified personal trainer in Baltimore. He's also CEO and founder of Fit2Go Personal Training.

Weight loss is caused by burning more calories than you consume. This fact leads some people to assume that the type of exercise that burns the most calories will also produce the most fat loss, Singer says. That's an incorrect assumption.

"In reality, strength training is the most effective type of exercise to reduce body fat percentage," Singer says.

It's important to distinguish the difference between weight loss and fat loss, he explains. "For most people, their actual weight isn't really what they care about," he says. "They don't care about how heavy they are. They care about how lean they are. When your body is in a caloric deficit, it will burn anything it can for energy. That means it will burn fat, yes, but it will also burn muscle tissue."

The way to counteract this is to engage in weight training, which tells your body that it needs the muscles being exercised, Singer says. "This leaves your body with no choice but to burn fat, leading to a leaner body as a result," he says.

Resistance or weight training has other benefits, adds Jonathan Jordan, a personal trainer based in San Francisco. "Strength training helps ensure healthy bones, joints and muscles," he says. "It builds lean muscle mass, which is incredibly important as we age."

Research suggests that weight training is important when it comes to decreasing body fat.

For example, a study published in 2017 in the journal Obesity suggests that weight training in combination with a low-calorie diet can help older adults become slimmer while preserving lean muscle mass that might be lost through aerobic workouts.

Researchers at Wake Forest University studied obese or overweight adults who were in their 60s. The study suggests that participants who lost weight and engaged in resistance training lost less lean mass than those who shed pounds through aerobic training.

Cardiovascular health. With a name like cardiovascular exercise, it stands to reason that cardiovascular exercise would benefit heart health. And it does. However, it's important to note that all exercise increases the workload on the heart and lungs and is therefore cardiovascular to some degree. While cardiovascular is the most common term, aerobic is the more scientifically accurate term for activities such as jogging and cycling.

"Of the two, aerobic or cardiovascular training is more directly important than anaerobic or strength training, since it more effectively builds aerobic fitness (the body's ability to deliver oxygen to tissues and use it)," says Vigil.

Strength training and the muscular adaptations that come with it affects heart health more indirectly. By increasing muscle mass, it gives your cardiovascular system more places to store its blood, thereby reducing blood pressure on the arterial walls, explains Scott Collier, a researcher and professor of cardiovascular exercise science at Appalachian State University in Boone, North Carolina.

By reducing levels of visceral fat, strength training also significantly lowers heart disease risk, says Andrew R. Coggan, associate professor of kinesiology and integrative physiology at Indiana University-Purdue University Indianapolis. In fact, regardless of overall body fat percentage, carrying excess visceral fat increases the risk of cardiovascular disease, according to a 2016 study published in the Journal of the American College of Cardiology. And a previous 2015 study from the journal The Lancet identified grip strength a widely recognized surrogate for total-body muscle strength as more accurately predicting the likelihood of death by heart disease than blood pressure.

Muscle health. There are two main varieties of muscle cells, or fibers: type 1 (also called slow-twitch or aerobic) and type 2 (known as fast-twitch or anaerobic), says Coggan.

Low-intensity or sustained cardiovascular exercise (movements longer than a few minutes) primarily use the type 1 fibers, Coggan says. The fibers that are trained are the ones that adapt. They do so largely through increasing the size and number of mitochondria, the microscopic oxygen-using power plants within your muscle cells, as well as capillaries, small blood vessels that bring nutrients including oxygen to the body's tissues, while removing carbon dioxide and other waste products, he says. These adaptations increase muscle endurance.

These are good cardio exercises for type 1 muscle fibers:

However, high-intensity, sprint-like cardiovascular exercise as well as strength training, especially at a high intensity, predominantly works type 2 muscle fibers, though such exercises also work type 1 fibers to a lesser extent. During a process called hypertrophy, muscle fibers adapt: The contractile units of each muscle cell grow and, eventually, the muscles as a whole are larger. As the contractile units grow, the muscle is better able to contract, resulting in greater strength and power, Rebold says.

Video: Calorie counters on treadmills and ellipticals aren't as accurate as you may think (Business Insider)


If you're about to start weight training, it's best not to begin with heavy weights or resistance that can tire or injure muscles or joints, says Dr. Richard C. Becker, a professor of medicine at the University of Cincinnati College of Medicine. He's also director of the college's Heart, Lung and Vascular Institute.

These exercises are good for type 2 muscle fibers:

Longevity. A raft of research suggests that being physically active including engaging in strength and cardio training is associated with living longer.

A study published in 2019 in the journal BMJ suggests that middle-aged and older adults, including individuals with heart disease and cancer, "stand to gain substantial longevity benefits by becoming more physically active, irrespective of past physical activity levels and risk factors."

"When compared to one another, a person doing only cardiovascular training and no strength training would stand to improve longevity more than a person who only engages in strength training," Vigil says. "This would be ill-advised, however, since the two forms of exercise are complementary to one another. This is especially true for the aging population who depend on adequate strength and balance to prevent falls and complications resulting from fall-related injuries."

According to the Centers for Disease Control and Prevention, falls are the leading cause of injury and death among adults age 65 and older.

However, recent research shows that maintaining muscle mass as you age, for which you need strength training, is a leading indicator of how long you will live and how healthy those years will be. A 2017 Current Opinion in Clinical Nutrition & Metabolic Care study found that lean muscle mass even outperforms body mass index at gauging overall health.

Keep in mind that you don't have to run a marathon or log hours at the gym to benefit from increased physical activity. Walking, stretching and practicing yoga movements are all considered physical activity, Becker says.

Slideshow: The 50 all-time best exercises for weight loss (Courtesy: The Active Times)

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When the World Stops Working, We Will Know the Truth – SFGate

§ February 25th, 2020 § Filed under Nano Medicine Comments Off on When the World Stops Working, We Will Know the Truth – SFGate

By Deepak Chopra, MD

Everyone looks at the world, and their lives, assuming that they know the truth. This isnt truth with a capital T but simply the truth about everyday things, like how to drive a car, buy groceries, and do ones job. We know other basic things that are true, such as when we are awake as opposed to being asleep. In other words, the world works, more or less to our satisfaction.

Somewhere beyond everyday affairs there are experts, professionals, and thinkers who deal in deeper truths, still not with a capital T but getting closer. Scientists especially are trusted to give us the truth about Nature from the most microscopic regions of quanta to the most cosmic regions, where quasars and black holes exist. We trust that if the everyday world is working, science must have a handle on why it works, operating from its deeper perspective.

So it comes as something of a shock, even though it doesnt touch us personally, that the scientific view of the world is so wobbly that it is on the verge of becoming either untrue or obsolete or both. At the farthest edges of exploration, the basic elements of physicsspace, time, matter, and energyvanish, either because they disappear into a black hole or because the scale of measurement reaches the limit, known as the Planck scale, where there is no way to calculate anything. At the same time there is the whole issue of dark matter and energy, which are barely known and may not be knowable by the human mind, since our brains are set up for regular matter and energy.

Because the scientific world stops working so far away from everyday life, including the everyday life of 99.99% of professional scientists, why should anyone but cosmologists, quantum physicists, and abstract theoreticians care? Even they rely upon their cars to get to the places where they do their advanced theoretical thinking.

The reason we should care has to do with that elusive thing, truth with a capital T. When it felt secure about space, time, matter, and energy (i.e., ever since Galileo and Newton), science thought it was getting closer to truth with a capital T, otherwise known as the Theory of Everything. If you know that the world, including the human brain, is totally based on material things, eventually you can compute every natural process, and you could declare that everything has been explained.

But if there are all kinds of things that do not have a material explanation, you are back at square one, because truth with a capital T is actually where our models of the world come from. In an age of faith God was truth with a capital T. Posit the existence of God, totally believe in this model of reality, and you are set until something comes along to disprove your model.

Science felt that it disproved the existence of God, because God isnt subject to scientific measurement, data collecting, experiments, and the replication of experimental results. But there are other things besides God that are disproving science. Maybe black holes, dark matter and energy, and the origin of the universe will one day be squeezed back into some kind of materialistic model, but it is clear that one thingthe mindcannot.

In a recent dialogue with the farseeing cognitive psychologist Donald D. Hoffman, we started from a premise that will shock most people. The objects we perceive around us only exist because our perception is trained to perceive them. There are no atoms, quarks, quasars, trees, clouds, or even the human brain, without humans constructing them to fit our way of navigating the world. Prof. Hoffmans view is based on evolution. His basic premise is that creatures survive not by seeing reality but by adapting to survival signals. A cat will ignore everything in a room except a mouse, driven to catch and eat it. If the cat paid attention to reality, i.e., everything in the room, it would have gone extinct long ago.

Humans beings are more complex in our evolution, because so much of it is based on the higher brain, but we still only perceive the tiniest fraction of electromagnetic frequencies, for example, and hear only a middle slice of sound frequencies. Using our higher brains we have constructed a human world, and as long as it works, we feel okay. We are not overly concerned that we cannot see the infrared spectrum or hear the ultrasonic spectrum.

No one would disagree that humans have our own specific models of reality, but the niggling problem of truth with a capital T enters the picture. If you trust your five senses to bring you the real world, your notion of truth with a capital T has no basis, because when you trace sight, sound, touch, taste, and smell back to the brain, the trail ends. As Prof. Hoffman puts it, despite decades of effort and the input of brilliant neuroscientists and related cognitive sciences, no one has shown that any brain activity can be measured scientifically to cause a single thing we perceive out there in the world.

The brain is certainly active all the time, but it is dark, soundless, and silent. There is no way to get at truth with a capital T when you start with the brain.

So, if God is no longer truth with a capital T, and the material-physical basis of science is quickly losing its grip on truth with a capital T, what does reality actually rest on? This is a fascinating question, because only when the world stops working can you see beyond false assumptions and old conditioning to get a view of the truth. The purpose of this post is simply to get us to that point. In the next post well see how the truth and reality can be reframed in a way that makes our persona lives quite different from what we assume them to be.

(To be cont.)

DEEPAK CHOPRA MD, FACP, founder of The Chopra Foundation, a non-profit entity for research on well-being and humanitarianism, and Chopra Global, a modern-day health company at the intersection of science and spirituality, is a world-renowned pioneer in integrative medicine and personal transformation. Chopra is a Clinical Professor of Family Medicine and Public Health at the University of California, San Diego and serves as a senior scientist with Gallup Organization. He is the author of over 89 books translated into over forty-three languages, including numerous New York Times bestsellers. Chopra is a Clinical Professor of Family Medicine and Public Health at the University of California, San Diego and serves as a senior scientist with Gallup Organization. His 90th book, Metahuman: Unleashing Your Infinite Potential, unlocks the secrets to moving beyond our present limitations to access a field of infinite possibilities. TIME magazine has described Dr. Chopra as one of the top 100 heroes and icons of the century.

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Cancer seen in humans also found in 66M-year-old dinosaur fossil – The Union Journal

§ February 25th, 2020 § Filed under Nano Medicine Comments Off on Cancer seen in humans also found in 66M-year-old dinosaur fossil – The Union Journal

A sort of cancer that despite everything harrows humans has been found in adinosaurfossil that was uncovered in Canada, according to specialists.

The fossil, which was found at the Dinosaur Provincial Park in southern Alberta, is of a little hadrosaur that was basic on the planet 66-80 million years back. It contains Langerhans cell histiocytosis (LCH), depicted as an uncommon and once in a while painful sickness that despite everything harrows humans, especially youngsters younger than 10, according to an announcement from Tel Aviv University.

The smaller scale CT creates high-goals imaging, up to a couple of microns, one of the examinations co-creators, Dr. Hila May, said in the statement. We checked the dinosaur vertebrae and made an electronic 3D recreation of the tumor and the veins that nourished it. The miniaturized scale and full-scale investigations affirmed that it was, indeed, LCH. This is the first run through this ailment that has been recognized in a dinosaur.

The size and state of the depressions in the fossil are what pulled in the consideration of the analysts, May included.

They were very like the depressions delivered by tumors related with the uncommon infection LCH that despite everything exists today in humans, May explained. The majority of the LCH-related tumors, which can be extremely painful, out of nowhere show up in the bones of youngsters matured 2-10 years. Fortunately, these tumors vanish without intervention in numerous cases.

The revelation is surprising, not just in that the illness endures in excess of 60 million years, yet that it isnt exceptional to humans.

These kinds of studies, which are currently conceivable gratitude to innovative innovation, make a significant and interesting commitment to transformative medicine, a moderately new field of research that investigates the improvement and conduct of illnesses after some time, Tel Aviv University teacher Israel Hershkovitz included the announcement. We are trying to comprehend why certain sicknesses endure advancement with the end goal of deciphering what makes them in request grow new and compelling methods for treating them. The investigation was distributed inScientific Reports.

Read More: Fortnite Chapter 2 Season 2 Promotions Include Real World Ads and Cryptic Messages

Specialists continue to become familiar with the hour of the dinosaurs, including theasteroidthat brought about their extinction.

The space rock, which hit Earth in the Yucatan Peninsula in Mexico, cleared out about 75 percent of all species on the planet. However, it might have brought about microscopic organisms being ready to flourish, according to an investigation published earlier this month.

A separatestudy distributed in October 2019, recommends the asteroidacidified Earthsoceans after its impact.Another study distributed in September 2019 contrasted the effect of the space rock with the force of10 billion nuclear bombs.

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Coming Weeks ‘Critical’ in Spread of Coronavirus – TheStreet

§ February 23rd, 2020 § Filed under Nano Medicine Comments Off on Coming Weeks ‘Critical’ in Spread of Coronavirus – TheStreet

As the Wuhan coronavirus tightens its grip around the globe, medical experts and economists alike now say the world is at a potentially historic juncture: Either quarantines and other public health measures will strangle the virus, or they will prove too slow and weak, and the pathogen will lash out, causing a pandemic.

I believe that the next few weeks will be critical in showing whether or not this virus will grow into a pandemic or remain confined to China, said Dr. Charles Chiu, a professor of medicine at the Division of Infectious Diseases at the University of California in San Francisco, in an email to TheStreet.

If the number of infections decreases and the outbreak becomes under control, it will validate the Chinese government's stringent measures to control spread such as imposing quarantines and limiting travel, said Chiu, who is also part of a team working on a new, rapid test for the virus. However, if we start to see sustained transmission in other countries, it would suggest that even these measures were not sufficient to control the epidemic, and global spread would be inevitable.

If the latter happens, the deadly pathogen could sicken most of the worlds population, overwhelm nations health care systems and chill the global economy.

In the case of a pandemic, for example, world gross domestic product growth would get whopped, losing out on $1.1 trillion for the full year, according to a report late last week from Oxford Economics.

But the human toll even if the overall death rate is around 2% or lower would also be devastating, say experts. Right now, it is believed that one in five people infected with the virus will develop severe disease.

If this became widespread it would put a burden on health care systems worldwide, because even though the percentages of deaths and severe cases isn't very high, the absolute numbers would be, said said Dr. Sanjaya Senanayake, an infectious disease expert and associate professor at Australian National University Medical School, in an email to TheStreet.

While Dr. Senanayake believes most people who survive would eventually recover and build up immunity to the disease caused by the virus, and that a vaccine would eventually be created, the outbreak would put pressure on hospitals already scrambling to care for patients during this flu season. He also notes that at least one estimate forecasts up to 60% of the global population becoming infected by the coronavirus if it isnt soon brought under control.

At last count early Sunday, nearly 79,200 people worldwide had the virus and the U.S.' total count was at 35.

Stepping back, one would see that while the global spread has been speedy, the disease in patients has been excruciatingly slow.

The nations first case a man in his 30s who returned from Wuhan to Washington state Jan. 15 was only released as virus-free a few days ago. The man was diagnosed not long after returning to the U.S. At first he had cold-like symptoms, and it wasnt until more than a week after that he was hospitalized with breathing difficulties. It took him well over a month until he was let out of isolation.

The story of U.S. patient No. 1 is dramatic when juxtaposed with the story of the outbreak itself. He essentially carried the virus from the time world first began learning about the person-to-person risk of COVID-19 in mid-January to now, as it has been diagnosed in nearly 80,000 people around the world and as people have now died from it in many countries outside of China: Italy, France, Taiwan, Japan, Iran, South Korea and more.

Even what appears to be milder cases are dragging on. In Boston, for example, a college student returning from Wuhan was confirmed to have the virus on Jan. 31. He sought care days earlier, out of fear he had been infected. As of Friday, the student was still at home in self-isolating at his off-campus home, Boston public health officials told TheStreet.

In a way, these cases could be seen as metaphors for whats happening globally: The initial fear of the infection, the uncertainties of the virus, the quarantines and other restrictions, the experimental treatments for a disease with no known cure or vaccine, and then the long wait to see how bad or manageable things get.

If it turns out the world isnt as lucky as the U.S. first patient, then the implications for public health and world economies will be great.

With widespread circulation of the virus locally, mass quarantine becomes difficult to impossible, said Chiu. It is unlikely, for instance, that the stringent measures that are being taken by China to prevent spread could be implemented or enforced in the United States. The next focus from a public health perspective would be in developing effective therapeutics or vaccines if we are unable to prevent the virus from spreading.

By the weekend, it appeared the world was swerving in the direction of that crisis as the numbers of patients outside China continue to grow.

The window of opportunity is narrowing, so we need to act quickly before it closes completely, said the World Health Organizations director-general Tedros Adhanom Ghebreyesus on Friday, according to Reuters.

This outbreak could go in any direction. If we do well, we can avert any serious crisis, but if we squander the opportunity then we will have a serious problem on our hands.

U.S. health officials said the same day theyre also beginning to prepare for a potential spread of the virus here, as is happening in several other nations outside of China, such as Italy, Singapore, Japan and South Korea, which recorded more than 760 cases by Sunday night.

Were not seeing spread here in the United States yet, but it is possible, even likely, that it may eventually happen, Dr. Nancy Messonnier of the Centers for Disease Control and Prevention told reporters on Friday. Our goal continues to be slowing the introduction of the virus into the U.S. This buys us more time to prepare our communities for more cases and possibly sustained spread. This new virus represents a tremendous public health threat.

The CDC is now working with state and local health departments, businesses and health care suppliers, to better respond to new cases and the possibility of a pandemic.

Forecasting what unfolds next would be difficult. Questions still remain about the virus, its diseases effects on the body, recovery time, and fatality rate. A vaccine wont arrive until at least sometime in mid-2021 andexperts told TheStreet last week that might even be wishful thinking. Available tests even have shortcomings.

The challenges of diagnosing patients cannot be taken lightly: They make containing and tracking the virus all the more difficult.

Because viral loads in patients appear to fluctuate, the main test currently used can be unreliable for "ruling out" infection, said Chiu. That test is also currently only available at the CDC and in a handful of state and local public health laboratories.

There is still a need for a quick, reliable test that can be done locally and which has a rapid turnaround time, said Chiu, to guide prompt isolation, contact tracing, and treatment. There is also a need for a test that can be run several times a day if needed to monitor patients under quarantine or infected patients in the hospital.

The test hes working on with MammothBiosciences in San Francisco would help provide results faster, within about 30 minutes. It could also be used in airports, emergency rooms and community hospitals including those in poor countries. But Chiu cautioned that it would have some of the same problems of diagnosing patients during the incubation period, when disease carriers may be contagious but not yet showing symptoms.

When news of the Wuhan coronavirus first began dominating headlines, comparisons were quickly made to the SARS outbreak of the earlier 2000s. Now, its clear that this particular coronavirus is a different animal.

In terms of economic impact, it is widely expected to be worse than in 2003 given the much bigger role that China plays in the global economy, said Oxford Economics economist Sung Eun Jung and lead economist Adam Slater, in an email to TheStreet.

Oxfords paper on the two possibilities for the coronavirus include an Asian pandemic scenario, in which Asian economies closely dealing with China see significant outbreak, and a global pandemic. Basing its forecasts on the earlier SARS and swine flu outbreaks, the paper sees lower discretionary consumption because of illness, travel restrictions, and people avoiding going out; a labor supply shock because many sickened people cant work and production is slowed; plummeting travel and tourism spending; lower investment because of uncertainties, falling demand and problems in supply chains; and a financial contagion that includes lower equity prices and rising money market spreads.

If the pain is mostly limited to Asia, then growth in the region slumps from around 4% at end-2019 to just 1.5% year-over-year in the first half of 2020. Chinese growth, meanwhile, would sink to 2.6% year-over-year in the first quarter of 2020.

Elsewhere in the world would get knocked from weakened trade, but would be helped by policies such as lower U.S. rates, according to the paper. Global GDP growth would decline to 1.5% year-over-year in the first half of 2020.

If the world falls ill, then in the first half of the year GDP growth would sink to nearly zero, and for full-year 2020, it takes a $1.1 trillion or 1.3% haircut. The U.S. and eurozone enter technical recessions in the first half of the year, too.

Its hard to put an exact number to the probability of each scenario, said Slater, one of the reports authors, in an email to TheStreet. One could look at the speed at which China is returning to business as usual to gauge the extent of the negative impact. Business surveys of sentiment and activity coming out over the coming weeks could give us a sense, but they are also notoriously volatile. We continue to forecast the negative economic effects to be concentrated in (the first half of the year) and the outbreak would then start to come under control.

But what if it doesnt? The virus is already hitting seemingly invincible giants such as Apple(AAPL) - Get Report, and a slew of other technology companies, both inside and outside of China. Major conferences are getting canceled.

And if the U.S. imposed restrictions like those seen in China and panic grips the nation after cases pop up here with no apparent connection to international travelers what would be the psychological, health and economic consequences?

As the CDCs Messonnier said on Friday, if youre watching the news, you may be hearing about schools shutting down and businesses closing in countries in Asia to reduce the potential spread of this virus. The day may come where we need to implement such measures in the U.S....

Will that day come? Time will tell.

But with the current explosion of cases in countries like Italy, Korea and Japan, and the more than 1,300 known infections in 26 countries outside of China, this microscopic threat so elusive even the best tests cant always spot it with certainty seems even more difficult that ever before to put back into the bottle.

This story has been updated. To reach the reporter, email here.

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$19.8B Synthetic Biology Market by Tools, Technology, Application and Region – Forecast to 2025 – Yahoo Finance

§ February 23rd, 2020 § Filed under Nano Medicine Comments Off on $19.8B Synthetic Biology Market by Tools, Technology, Application and Region – Forecast to 2025 – Yahoo Finance

Dublin, Feb. 17, 2020 (GLOBE NEWSWIRE) -- The "Synthetic Biology Market by Tools (Oligonucleotides, Enzymes, Synthetic Cells), by Technology (Gene Synthesis, Bioinformatics), by Application (Tissue Regeneration, Biofuel, Renewable Energy, Food & Agriculture, Bioremediation) - Global Forecast to 2025" report has been added to's offering.

The global synthetic biology market is projected to reach USD 19.8 billion by 2025 from USD 6.8 billion in 2020, at a CAGR of 23.9%.

This report analyzes the market for various synthetic biology market and their adoption patterns. It aims at estimating the market size and future growth potential of the synthetic biology market and its subsegments. The report also includes an in-depth competitive analysis of the key players in this market, along with their company profiles, product offerings, and recent developments.

Factors such as the increasing demand for synthetic genes and synthetic cells, wide range of applications of synthetic biology, declining cost of DNA sequencing and synthesizing, increasing R&D funding and initiatives in synthetic biology, and increasing investments in the market are propelling the growth of this market. However, rising biosafety, biosecurity, and ethical concerns related to synthetic biology are likely to hamper the growth of this market.

The oligonucleotides and synthetic DNA segment is expected to grow at the highest rate during the forecast period

Based on tools, the market has been segmented into oligonucleotides and synthetic DNA, enzymes, cloning technology kits, chassis organisms, xeno-nucleic acids, and synthetic cells. In 2019, the oligonucleotides and synthetic DNA segment is expected to register the highest CAGR during the forecast period.

This can be attributed to factors such as the rising demand for synthetic DNA, synthetic RNA, and synthetic genes, which are used in a wide range of applications, such as pharmaceuticals, nutraceuticals, personal care, flavors and fragrances, probiotics, green chemicals, and industrial enzymes.

The genome engineering segment is expected to grow at the highest CAGR during the forecast period

On the basis of technology, the market is segmented into gene synthesis, genome engineering, cloning, sequencing, site-directed mutagenesis, measurement and modeling, microfluidics, nanotechnology, bioinformatics technologies.

The genome engineering segment is expected to register the highest CAGR during the forecast period due to factors such as the increasing use of engineering technologies for manipulating complex genomes, growing therapeutics development for cancer and other diseases, and the increasing technological advances in CRISPR-toolbox and DNA synthesis technologies.

The industrial applications segment is expected to grow at the highest CAGR during the forecast period

Based on application, the synthetic biology market is segmented into medical, industrial, food & agricultural, and environmental applications. The industrial applications segment is expected to grow at the highest CAGR owing to the rising applications of synthetic biology in producing renewable energy, biomaterials & green chemicals, and enzymes.

The Asia Pacific is projected to witness the highest growth during the forecast period

The synthetic biology market is divided into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. In 2019, North America accounted for the largest share of the synthetic biology market.

However, the APAC region is expected to witness the highest growth during the forecast period owing to the growth in the number of pharmaceutical & biopharmaceutical companies, the increasing number of healthcare & life science facilities, and increasing requirements for regulatory compliance in pharmaceutical and biopharmaceutical companies, growing number of international alliances, heavy funding for synthetic biology research, and strong government support.

Furthermore, the increasing focus on the Asia Pacific markets due to their low-cost manufacturing advantage also provides growth opportunities for manufacturers.

Key Topics Covered

1 Introduction

2 Research Methodology

3 Executive Summary

4 Premium Insights 4.1 Market Overview4.2 Asia Pacific: Market, By Application4.3 Market: Geographic Growth Opportunities4.4 Market, By Region (2018-2025)4.5 Market: Developed vs. Developing Markets

5 Market Overview 5.1 Introduction5.2 Market Dynamics5.2.1 Drivers5.2.1.1 Wide Range of Applications of Synthetic Biology5.2.1.2 Rising R&D Funding and Growing Initiatives in Synthetic Biology5.2.1.3 Declining Cost of DNA Sequencing and Synthesizing5.2.1.4 Increasing Investments in the Market5.2.2 Restraints5.2.2.1 Biosafety, Biosecurity, and Ethical Concerns5.2.3 Opportunities5.2.3.1 Rising Need for Fuel Alternatives5.2.3.2 Increasing Demand for Protein Therapeutics and Personalized Medicine5.2.3.3 Increasing Research in Synthetic Drugs and Vaccines5.2.4 Challenges5.2.4.1 Standardization of Biological Parts

6 Synthetic Biology Market, By Tool 6.1 Introduction6.2 Oligonucleotides & Synthetic DNA6.2.1 Oligonucleotides and Synthetic Dna to Dominate the Market During the Forecast Period6.3 Enzymes6.3.1 Development of Enzymes has Helped in Evolving New Therapies for A Range of Diseases6.4 Cloning Technology Kits6.4.1 Need for the Creation of Artificial Dna Along With Their Assembly is Driving the Growth of the Segment6.5 Synthetic Cells6.5.1 Synthetic Cells Will Allow Tailoring Biologics and Its Adoption is Expected to Grow in the Coming Years6.6 Chassis Organisms6.6.1 Increasing Demand for Fossil Fuels is Likely to Propel the Demand for Chassis Organisms6.7 Xeno-Nucleic Acids6.7.1 Xnas are Increasingly Researched With the Growing Demand for Breakthrough Medicine

7 Synthetic Biology Market, By Technology 7.1 Introduction7.2 Gene Synthesis7.2.1 Gene Synthesis to Dominate the Market During the Forecast Period7.3 Genome Engineering7.3.1 Increasing Demand for Synthetic Dna and Genes is Expected to Drive Market Growth7.4 Sequencing7.4.1 Ngs Technology is Rapidly Becoming an Indispensable and Universal Tool for Biological Research7.5 Bioinformatics7.5.1 Use of Bioinformatics Technologies is Increasing With the Rising Need for Data Management and Curation7.6 Cloning7.6.1 Cloning Aids in Building New Genetic Modules/Pathways, Enabling Rapid Advances in Research Across Various Industries7.7 Site-Directed Mutagenesis7.7.1 Wide Applications in Genetic Engineering, Dna Assembly, and Cloning Technologies is Driving This Segment7.8 Measurement & Modeling7.8.1 Computational Modeling is Aiding the Growth of the Segment During the Forecast Period7.9 Microfluidics7.9.1 Droplet Microfluidics is Gaining Wide Recognition in the Field of Synthetic Biology7.1 Nanotechnology7.10.1 Convergence Between Synthetic Biology and Nanotechnologies Aid in Building Complex Bodies

8 Synthetic Biology Market, By Application 8.1 Introduction8.2 Medical Applications8.2.1 Pharmaceuticals8.2.1.1 In 2019, the Pharmaceuticals Segment Accounted for the Largest Share of the Medical Applications Market8.2.2 Drug Discovery and Therapeutics8.2.2.1 Cancer Detection & Diagnostics8. With Rising Investments for Cancer Research, the Market for Synthetic Biology is Expected to Grow for This Segment8.2.2.2 Other Drug Discovery and Therapeutic Applications8.2.3 Artificial Tissue & Tissue Regeneration8.2.3.1 Bio-Synthesis8. Bio-Synthesis is Dominating the Market With Its Increasing Adoption in Creating Artificial Genomes8.2.3.2 Stem Cell Regulation8. Use of Synthetic Biology in Stem Cell Regeneration and Reprogramming Somatic Cells is Expected to Drive Market Growth8.2.3.3 Other Artificial Tissue and Tissue Regeneration Applications8.3 Industrial Applications8.3.1 Biofuel and Renewable Energy8.3.1.1 Advantages of Using Genetically Engineered Organisms for the Synthetic Production of Biofuels is Driving Market Growth8.3.2 Industrial Enzymes8.3.2.1 Textile Industry8. Synthetic Biology is Being Applied in the Textile Industry to Replace Traditional Raw Materials8.3.2.2 Paper Industry8. Enzymes are Being Increasingly Used in the Pulp and Paper Industry8.3.2.3 Other Industries8.3.3 Biomaterials & Green Chemicals8.3.3.1 Silk-Based Proteins are A Type of Biomaterial Prepared Through Synthetic Biology8.4 Food & Agriculture8.4.1 Synthetic Biology Techniques are Applied in the Food and Agriculture Industry to Produce Metabolites, Health Products, and Processing Aids8.5 Environmental Applications8.5.1 Bioremediation8.5.1.1 Owing to the Growing Severity of Environmental Problems, It has Become Necessary to Develop Cost-Effective, On-Site Methods for Environmental Monitoring and Bioremediation8.5.2 Biosensing8.5.2.1 Biosensor Applications Commonly Make Use of Microalgae Owing to Their High Reproductive Rates and Ease of Culturing Due to Their Microscopic Size

9 Synthetic Biology Market, By Region 9.1 Introduction9.2 North America9.2.1 US9.2.1.1 The US Dominates the North American Market9.2.2 Canada9.2.2.1 Strong Research Infrastructure and Availability of Funding Will Support Market Growth9.3 Europe9.3.1 UK9.3.1.1 The UK Holds the Largest Share of the European Market9.3.2 Germany9.3.2.1 The Rapidly Growing Pharmaceutical Market is Expected to Drive Market Growth9.3.3 France9.3.3.1 Research Across All Industries is Strongly Supported By the Government9.3.4 Denmark9.3.4.1 Denmark has the Third-Largest Commercial Drug-Development Pipeline in Europe9.3.5 Switzerland9.3.5.1 Market Growth is Primarily Driven By the Well-Established Pharmaceutical & Biotechnology Industry in the Country9.3.6 Spain9.3.6.1 Spain has A Well-Established Network of Research Centers, Universities, and Hospitals, Which Form an Ideal Environment for Research9.3.7 Italy9.3.7.1 Growth in This Market is Mainly Driven By Increasing Life Science R&D in the Country, Funded By Both Public and Private Organizations9.3.8 Rest of Europe9.4 Asia Pacific9.4.1 Japan9.4.1.1 Large Number of Research Initiatives Towards the Development of Precision Medicine Supporting Market Growth9.4.2 China9.4.2.1 Growth in R&D to Enhance the Technological Capabilities in the Country, Thereby Driving the Demand for High-Quality Research Tools9.4.3 Australia9.4.3.1 Increasing Focus of the Healthcare System on Precision Medicine to Offer Significant Growth Opportunities9.4.4 India9.4.4.1 Increasing Pharma R&D and Government Funding in the Biotechnology Industry are the Major Factors Driving Market Growth9.4.5 Rest of Asia Pacific9.5 Latin America9.5.1 Strong Pharmaceutical Industry in the Region to Provide Significant Growth Opportunities9.6 Middle East and Africa9.6.1 Increasing Partnerships Among Global Players With Government Organizations in the Region to Support Growth

10 Competitive Landscape 10.1 Overview10.2 Market Share Analysis10.2.1 Synthetic Biology Market, By Key Players, 201810.3 Competitive Leadership Mapping10.3.1 Visionary Leaders10.3.2 Innovators10.3.3 Dynamic Differentiators10.3.4 Emerging Companies10.4 Competitive Situation and Trends10.4.1 Product Launches10.4.2 Expansions10.4.3 Acquisitions10.4.4 Other Strategies

11 Company Profiles 11.1 Thermo Fisher Scientific Inc.11.1.1 Business Overview11.1.2 Products Offered11.1.3 Recent Developments11.2 Merck KGaA11.3 Agilent Technologies Inc.11.4 Novozymes A/S11.5 Ginkgo Bioworks11.6 Amyris Inc.11.7 Intrexon Corporation11.8 Genscript Biotech Corporation11.9 Twist Bioscience11.10 Synthetic Genomics Inc. (SGI)11.11 Codexis Inc.11.12 Synthego Corporation11.13 Creative Enzymes11.14 Eurofins Scientific11.15 Cyrus Biotechnology Inc.11.16 Other Major Companies11.16.1 Atum11.16.2 Teselagen11.16.3 Arzeda11.16.4 Integrated DNA Technologies Inc.11.16.5 New England Biolabs

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$19.8B Synthetic Biology Market by Tools, Technology, Application and Region - Forecast to 2025 - Yahoo Finance

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Sleuths Uncover Web of Research Fraud in 400+ Papers From China – The Wire

§ February 23rd, 2020 § Filed under Nano Medicine Comments Off on Sleuths Uncover Web of Research Fraud in 400+ Papers From China – The Wire

Elisabeth Bik, the microbiologist and research integrity consultant noted for unearthing evidence of research misconduct, tweeted on February 21that she and some others had uncovered over 400 scientific papers that all share a very similar title layout, graph layout, and (most importantly) the same Western blot layout indicating an organised web of potential fraud. She also expressed concern that there might be hundreds of papers more, and that she and her collaborators may just have spotted the obviously fraudulent ones.

Western blotting is a technique that microbiologists employ to identify the proteins present in a tissue sample. As an analytical technique involving real-world materials, no two images of western blots are supposed to look alike, and similarities suggest the image may have been manipulated, inadvertently or otherwise.

Guided by this and similar giveaways, Bik, @SmutClyde, @mortenoxe and @TigerBB8 (all Twitter handles of unidentified persons), report as written by Bik in ablog post that the Western blot bands in all 400+ papers are all very regularly spaced and have a smooth appearance in the shape of a dumbbell or tadpole, without any of the usual smudges or stains. All bands are placed on similar looking backgrounds, suggesting they were copy-pasted from other sources or computer generated.

Bik also notes that most of the papers, though not all, were published in only six journals: Artificial Cells Nanomedicine and Biotechnology,Journal of Cellular Biochemistry,Biomedicine & Pharmacotherapy,Experimental and Molecular Pathology,Journal of Cellular Physiology, andCellular Physiology and Biochemistry, all maintained reputed publishers and importantly all of them peer-reviewed.

As a result, the discovery of the problem papers has prompted concerns about the ability of peer-review to check research misconduct in the scientific community.

Indeed, when Bik writes, Finding these fabricated images should not rely solely on the work of unpaid volunteers, she evidently means herself and her collaborators but her words also apply to peer-reviewers, who are unpaid for their work and often lack both the resources and the inclination to investigate each paper in close detail. As a result, peer-review is often not the insurmountable defence some proclaim it to be, nor are peer-reviewed journals as free of bogus science as they claim to be.

As Madhusudhan Raman, a postdoctoral scholar at the Tata Institute of Fundamental Research, Mumbai,wrote inThe Wire, any attempt to radically change the nature of peer-review must necessarily be accompanied by a change in the way the referees are compensated for their time and effort, especially within academia.

A PubPeer user who goes by Indigofera Tanganyikensis first identified the problem in two papers (thisandthis) both published by Chinese researchers. On February 17 this year, a little under a week before Bik published her blog post, two American researchers Jennifer A. Byrne and Jana Christopher published an articlediscussing similar research misconduct based on 17 papers they had discovered.

According to Bik, As it turns out, Byrne and Christophers publication describes the exact same set of papers that our small team of image forensics detectives had been working on in the past month.

These sleuths, as @SmutClydewrote on Leonid Schneiders blog, believe they have stumbled upon at least one paper mill. To quote (selectively) from Biks post,

A paper mill is a shady company that produces scientific papers on demand. They sell these papers to [people] who do not have any time in their educational program to actually do research. Authorships on ready-to-submit or already-accepted papers are sold to medical students for hefty amounts. Whether or not the experiments described in these papers has actually been performed is not clear. Some of these paper mills might have laboratories producing actual images or results, but such images might be sold to multiple authors to represent different experiments. Thus, the data included in these papers is often falsified or fabricated.

The mills seem to have been hired by Chinese clinicians affiliated to various medical colleges and hospitals in China (234 of the 400+ papers have been authored by people affiliated to institutions in Shandong province). The papers were all published between 2016 and 2020. @SmutClyde wrote that after they publicised their findings, including thedataset of papers they had identified as potentially fraudulent (and which they continue to update), an author of one of the papers wrote in:

Being as low as grains of dust of the world, countless junior doctors, including those younger [than] me, look down upon the act of faking papers. But the system in China is just like that, you cant really fight against it. Without papers, you dont get promotion; without a promotion, you can hardly feed your family. I also want to have some time to do scientific research, but its impossible. During the day, I have outpatient surgeries; after work, I have to take care of my kids. I have only a little bit time to myself after 10 pm, but this is far from being enough because scientific research demands big trunks of time. The current environment in China is like that.

Considering how the peer-review of all of those journals have failed, what the detectives have found effectively represents a large volume of unscientific data entering the scientific literature, funnelled predominantly by Chinese researchers who probably hired a paper mill to help meet the publishing requirements set by their respective institutions. Bik wrote that it is of great concern to see that this specific paper mill has successfully infected particular journals and that it is very alarming to see that journal editors do not appear to have noticed the similarities between dozens of papers published in their journals.

This said, the note from the unnamed Chinese author indicates the source of the problem is hardly new or even confined to China.

For example, until Prakash Javadekar, then the Union human resource development minister, said in mid-2017 that college teachers would not be required to undertake research to qualify for promotions, people who had not trained for research and have since been embedded in environments not properly equipped to support research were forced to conduct research, and publish papers.

Javadekar is to be loudly applauded and congratulated for taking this measure,Pushkar wrote forThe Wireat the time. The research requirement in the [Academic Performance Indicators] for college teachers was a travesty. All that it achieved was a proliferation of fake journals for college teachers to publish in.

Indeed, India has come to be known the fake journals capital of the world, partly as a result of requiring people who cannot undertake research to undertake research, and partly because research productivity has become one of the core measures of determining whether a country is a scientific superpower.

For another example, the journalNaturereportedthat Pakistans research output increased the most among all countries in the world by 21% in 2018, a feat that it dubbed a phenomenal success. However, as Anjum Altaf, former provost of Karachis Habib University and a famous teacher, subsequentlytoldThe Wire, The volume of third-rate publications in Pakistan has increased greatly simply because [Pakistans Higher Education Commission] introduced a tenure-track system and required publications for promotion.

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Sleuths Uncover Web of Research Fraud in 400+ Papers From China - The Wire

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Sleep Medicine Market Research by Industry Growth Factors, Size, Top Companies Analysis, Share and Forecast 2020-2025 – Nyse Nasdaq Live

§ February 22nd, 2020 § Filed under Nano Medicine Comments Off on Sleep Medicine Market Research by Industry Growth Factors, Size, Top Companies Analysis, Share and Forecast 2020-2025 – Nyse Nasdaq Live

Global Sleep Medicine Market Research Report offers detailed survey of market insight in communicative format, covering past from 2015-2019 and calculating 2020-2025.The predominant applications wise data has also been discussed at length in this research study with various Sleep Medicine market. It also provides complete professional and extensive analysis of global Sleep Medicine Market demand, standardization, deployment models, business challenges, industry opportunities and historical data with expert opinions.

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Global Sleep Medicine (OBC) Market: Drivers and Restrains

This report mainly elaborates the definition, types, applications and major players of Sleep Medicine market in details. Deep analysis about market status (2014-2019), enterprise competition pattern, advantages and disadvantages of enterprise products, industry development trends (2019-2024), regional industrial layout characteristics and macroeconomic policies, industrial policy has also be included. From raw materials to downstream buyers of this industry will be analyzed scientifically, the feature of product circulation and sales channel will be presented as well. In a word, this report will help you to establish a panorama of industrial development and characteristics of the Sleep Medicine market.

The major players in the marketinclude

Most important types of Sleep Medicine products covered in this report are:

Most widely used downstream fields of Sleep Medicine market covered in this report are:

A thorough evaluation of the restrains included in the report portrays the contrast to drivers and gives room for strategic planning. Factors that overshadow the market growth are pivotal as they can be understood to devise different bends for getting hold of the lucrative opportunities that are present in the ever-growing market. Additionally, insights into market experts opinions have been taken to understand the market better.

Market Segment Analysis

The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2025. Application segment also provides consumption during the forecast period of 2015 to 2025. Understanding the segments helps in identifying the importance of different factors that aid the market growth.

Global Sleep Medicine (OBC) Market: Regional Analysis

The report offers in-depth assessment of the growth and other aspects of the Sleep Medicine (OBC) market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America.

The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2025. These analyses will help the reader to understand the potential worth of investment in a particular region.

Global Sleep Medicine (OBC) Market: Competitive Landscape

This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019.

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Table of Contents

1 Sleep Medicine (OBC) Market Overview

2 Market Competition by Manufacturers

3 Production Capacity by Region

4 Global Sleep Medicine (OBC) Consumption by Regions

5 Production, Revenue, Price Trend by Type

6 Global Sleep Medicine (OBC) Market Analysis by Application

7 Company Profiles and Key Figures in Sleep Medicine (OBC) Business

8 Sleep Medicine (OBC) Manufacturing Cost Analysis

9 Marketing Channel, Distributors and Customers

10 Market Dynamics

11 Production and Supply Forecast

12 Consumption and Demand Fprecast

15 Methodology and Data Source

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Hematology Analyzers & Reagents Market 2020 Global Industry Growth Analysis, Segmentation, Size, Share, Trend, Future Demand And Leading Players…

§ February 22nd, 2020 § Filed under Nano Medicine Comments Off on Hematology Analyzers & Reagents Market 2020 Global Industry Growth Analysis, Segmentation, Size, Share, Trend, Future Demand And Leading Players…

The Latest Research Report on Hematology Analyzers & Reagents Market size | Industry Segment by Applications, by Type, Regional Outlook, Market Demand, Latest Trends, Hematology Analyzers & Reagents Industry Share & Revenue by Manufacturers, Company Profiles, Growth Forecasts 2025. Analyzes current market size and upcoming 5 years growth of this industry.

The new report offers a powerful combination of latest, in-depth research studies on the Hematology Analyzers & Reagents market. The authors of the report are highly experienced analysts and possess deep market knowledge.

Download Sample Copy of the Report to understand the structure of the complete report (Including Full TOC, Table & Figures):

Major Countries Analyzed Under This Report are:

SysmexMindrayHORIBANihon KohdenSinnowaTecom SciencePerlongMexcomBeckman CoulterAbbott LaboratoriesBeckman CoulterBio-RadDesco MedicalDruckerSiemens

Hematology Analyzers & Reagents Players/Suppliers Profiles and Sales Data: Company, Company Basic Information, Manufacturing Base and Competitors, Product Category, Application and Specification with Sales, Revenue, Price and Gross Margin, Main Business/Business Overview.

Table Of Content

Market Overview: Scope & Product Overview, Classification of Hematology Analyzers & Reagents by Product Category (Market Size (Sales), Market Share Comparison by Type (Product Category)), Hematology Analyzers & Reagents Market by Application/End Users (Sales (Volume) and Market Share Comparison by Application), Market by Region (Market Size (Value) Comparison by Region, Status and ProspectHematology Analyzers & Reagents Market by Manufacturing Cost Analysis:Key Raw Materials Analysis, Price Trend of Key Raw Materials, Key Suppliers of Raw Materials, Market Concentration Rate of Raw Materials, Proportion of Manufacturing Cost Structure (Raw Materials, Labor Cost), Manufacturing Process Analysis

Key Benefits for Stakeholders

The study provides an in-depth analysis of the Hematology Analyzers & Reagents market size along with the current trends and future estimations to elucidate the imminent investment pockets.Information about key drivers, restraints, and opportunities and their impact analysis on the market size is provided.Porters five forces analysis illustrates the potency of buyers and suppliers operating in the portable gaming industry.The quantitative analysis of the Hematology Analyzers & Reagents industry from 2020 to 2026 is provided to determine the Hematology Analyzers & Reagents market potential.

Hematology Analyzers & Reagents Market is estimated to reach xxx million USD in 2020 and projected to grow at the CAGR of xx% during 2020-2026

The research report is broken down into chapters, which are introduced by the executive summary. Its the introductory part of the chapter, which includes details about global market figures, both historical and estimates. The executive summary also provides a brief about the segments and the reasons for the progress or decline during the forecast period. The insightful research report on the Hematology Analyzers & Reagents market includes Porters five forces analysis and SWOT analysis to understand the factors impacting consumer and supplier behavior.

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Market Segment Analysis

The research report includes specific segments by Type and by Application. Each type provides information about the production during the forecast period of 2015 to 2026. Application segment also provides consumption during the forecast period of 2015 to 2026. Understanding the segments helps in identifying the importance of different factors that aid the market growth.

Segment by Type 3-& 5- part hematology AnalyzersPoint-of-CareFully AutomatedOthers

Segment by Application Internal MedicinePediatricsOncology

Hematology Analyzers & Reagents Market: Competitive Landscape

This section of the report identifies various key manufacturers of the market. It helps the reader understand the strategies and collaborations that players are focusing on combat competition in the market. The comprehensive report provides a significant microscopic look at the market. The reader can identify the footprints of the manufacturers by knowing about the global revenue of manufacturers, the global price of manufacturers, and production by manufacturers during the forecast period of 2015 to 2019.

Hematology Analyzers & Reagents Market: Regional Analysis

The report offers in-depth assessment of the growth and other aspects of the Hematology Analyzers & Reagents market in important regions, including the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, Taiwan, Southeast Asia, Mexico, and Brazil, etc. Key regions covered in the report are North America, Europe, Asia-Pacific and Latin America.

The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2025. These analyses will help the reader to understand the potential worth of investment in a particular region.

Key Strategic Developments:The study also includes the key strategic developments of the Hematology Analyzers & Reagentsmarket, comprising R&D, new product launch, M&A, agreements, collaborations, partnerships, joint ventures, and regional growth of the leading competitors operating in the market on a global and regional scale.

Key Market Features:The report evaluated key market features, including revenue, price, capacity, capacity utilization rate, gross, production, production rate, consumption, market share, CAGR, and gross margin.Analytical Tools: The Hematology Analyzers & Reagents Market report includes the precisely studied and weighed data of the key industry players and their scope in the Hematology Analyzers & Reagents market by means of several analytical tools

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Hematology Analyzers & Reagents Market 2020 Global Industry Growth Analysis, Segmentation, Size, Share, Trend, Future Demand And Leading Players...

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Global Nanomedicines Market 2026 : Focus Their Efforts On Product Innovation In Order To Attract New Consumers – Chronicle 99

§ February 22nd, 2020 § Filed under Nano Medicine Comments Off on Global Nanomedicines Market 2026 : Focus Their Efforts On Product Innovation In Order To Attract New Consumers – Chronicle 99

The Nanomedicines market was valued at XX Million US$ in 2018 and is projected to reach XX Million US$ by 2024, at a CAGR of XX% during the forecast period. In this study, 2018 has been considered as the base year and 2019 to 2024 as the forecast period to estimate the market size for Nanomedicines.Global Nanomedicines industry market professional research 2014-2024, is a report which provides the details about industry overview, industry chain, market size (sales, revenue, and growth rate), gross margin, major manufacturers, development trends and forecast.

To access the sample report of the Nanomedicines market visit at:

Key players in global Nanomedicines market include:

AbbottGE HealthcareJohnson & JohnsonMerckPfizerCombiMatrixCelgeneMallinckrodtSigma-Tau PharmaceuticalsTeva PharmaceuticalNanosphereUCB SA

Market segmentation, by product types:


Market segmentation, by applications:

HospitalsClinicsResearch Institute

Market segmentation, by regions:

North America (United States, Canada)Europe (Germany, France, UK, Italy, Russia, Spain)Asia Pacific (China, Japan, Korea, India, Australia, New Zealand)Middle East & Africa (Middle East, Africa)Latin America (Mexico, Brazil, C. America, Chile, Peru, Colombia)

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The report can answer the following questions:1. North America, Europe, Asia Pacific, Middle East & Africa, Latin America market size (sales, revenue and growth rate) of Nanomedicines industry.2. Global major manufacturers operating situation (sales, revenue, growth rate and gross margin) of Nanomedicines industry.3. Global major countries (United States, Canada, Germany, France, UK, Italy, Russia, Spain, China, Japan, Korea, India, Australia, New Zealand, Southeast Asia, Middle East, Africa, Mexico, Brazil, C. America, Chile, Peru, Colombia) market size (sales, revenue and growth rate) of Nanomedicines industry.4. Different types and applications of Nanomedicines industry, market share of each type and application by revenue.5. Global market size (sales, revenue) forecast by regions and countries from 2019 to 2024 of Nanomedicines industry.6. Upstream raw materials and manufacturing equipment, industry chain analysis of Nanomedicines industry.7. SWOT analysis of Nanomedicines industry.8. New Project Investment Feasibility Analysis of Nanomedicines industry.

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About Us:Orbis Research ( is a single point aid for all your market research requirements. We have vast database of reports from the leading publishers and authors across the globe. We specialize in delivering customised reports as per the requirements of our clients. We have complete information about our publishers and hence are sure about the accuracy of the industries and verticals of their specialisation. This helps our clients to map their needs and we produce the perfect required market research study for our clients.

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Global Nanomedicines Market 2026 : Focus Their Efforts On Product Innovation In Order To Attract New Consumers - Chronicle 99

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Sunway University Researchers Recognised with the Vice-Chancellor’s Research Award – QS WOW News

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on Sunway University Researchers Recognised with the Vice-Chancellor’s Research Award – QS WOW News

In its aim towards becoming the countrys international education hub, Sunway University is moving forward in its pursuit of excellence not only in academia but also through innovative research.

At the end of last year, four Sunway University researchers were recognised with the Vice-Chancellors Research Award. The recipients were; Associate Professor Dr Yong Min Hooi from the Department of Psychology who received the Special Research Award, Professor Saidur Rahman of the Research Centre for Nano-Materials and Energy Technology with the Award for Achievement in Research, Dr Ayaz Anwar of the Department of Biological Sciences and Dr Hassanudin Mohd Thas Thaker from the Department of Economics and Finance who each received the Award for Achievement in Research for Early Career Researcher.

Associate Professor Dr Yong Min Hoois research focusses on ageing, specifically, executive function and social cognition in older adults. Dr Yong received the Long-Term Research Grant Scheme (LRGS) from the Ministry of Education Malaysia, amounting to RM2.47 million for a 5-year research on Successful ageing: Evidence-based interventions to delay ageing-related decline. This is first single largest grant received in the history of Sunway University. The five-year term from 1 December 2019, scheduled to be completed by 30 November 2024, is categorised under the Aging cluster within Health research cluster and governed under the Sunway Universitys Research Ethics Committee.

Dr Yong previously received various grants from the Newton-Ungku Omar Fund from British Council and the Malaysian Industry-Government Group for High Technology (MIGHT), Arts and Humanities Research Council UK, and Fundamental Research Grant Scheme (FRGS) from Ministry of Higher Education.

Professor Saidur Rahman is Head of the Research Centre for Nano-Materials and Energy Technology. His research focus is in the area of emerging nano-materials, applications in harvesting and storing of solar energy. He has been recognised as a highly cited researcher, listed as the top 1% researchers for most cited documents in his research field of nanofluids for the last 6 years (2014-2019).

Dr Ayaz Anwars current research projects focus on nanomedicine and medicinal chemistry for the development of antimicrobial chemotherapy. His research on silver nanoparticles targeting brain eating amoeba gained international coverage and was featured in the New York Times.

Dr Hassanudin Mohd Thas Thaker research focus in Islamic banking and finance, real estate finance, financial markets, derivatives, and economics has been recognised internationally, earning him the Emerald Literati award in 2016.

Sunway University has 9 research centres and one research group under its roof where research across various fields of study is encouraged.

Sunway University Researchers Recognised with the Vice-Chancellor's Research Award - QS WOW News

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Scopio Labs Enhances Digital Cytology Through The Launch Of Automated Imaging And Solutions For Veterinary Market – Pulse 2.0

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on Scopio Labs Enhances Digital Cytology Through The Launch Of Automated Imaging And Solutions For Veterinary Market – Pulse 2.0

Scopio Labs a company dedicated to advancing digital microscopy announced that the ScopioVet Digital Cytology System (already installed in dozens of veterinary clinics) is now available commercially throughout the United States and Canada. And ScopioVet is the first true end-to-end solution for veterinary digital cytology, consisting of Scopios proprietary microscopy imaging system an intuitive pathology consultation service and powerful AI tools that automate routine diagnostic tests. Plus ScopioVet enables veterinary clinics to scan and send cytology and hematology cases to a global network of clinical pathologists who provide round-the-clock analysis, within one hour.

The diagnostic practice of cytology and hematology is designed to be a less invasive and significantly faster option than histology, said Asher Fink, Veterinary Business Head and VP of Business Development for Scopio Labs. However, when veterinarians and pet parents wait several days for results to come back, as is the case in most veterinary practices worldwide, the value of cytology is reduced. ScopioVet corrects this dynamic, by providing results in less than an hour, unlocking the true value of cytology and improving the standard of care so veterinarians can deliver exceptional service with improved outcomes.

Scopio Labs proprietary digital microscopy platform scans microscope slides at 100X equivalent magnification and makes it the highest resolution and quality system in the world. And this resolution level is essential for analyzing the sample types generated at the veterinary point of care such as blood, fine needle aspirates and body fluids.

To provide a conclusive diagnosis for the range of sample types our customers process, 100X magnification is the gold standard, added Natalie Hoepp, DVM, MS, DACVP, Medical Director at Scopio Labs. Anything less will leave the clinical pathologist in doubt due to lack of finer microscopic detail, or worse they may not be able to accurately identify certain microscopic features at all. This will not serve the veterinarian or the patient, and creates diagnostic liability for our veterinary customers. The clear superiority of Scopios technology is one of the many reasons I chose to join their vision for the advancement of digital clinical pathology in veterinary medicine.

Scopio Labs also announced it has implemented powerful features that enable a seamless and comprehensive workflow at the veterinary point of care. For example, ScopioVet has a three slides tray, which allows for easy scanning of cases with more slides. And the service also includes an in-app pathologist chat feature, preferred pathologist routing, and immediate scan streaming which allows pathologists to review scans right away instead of waiting for them to finish uploading thus supporting a rapid turnaround time.

Scopio Labs is also developing artificial intelligence tools that support increased accuracy and efficiency. The first tool to launch now undergoing clinical validation is the platelet count estimate, which saves valuable technician time by quickly and accurately identifying platelets in peripheral blood smears and calculating volume per microliter.

Were bringing significant improvements to the veterinary workflow simply by digitizing the once-analog process of reviewing samples under a manual microscope, explained Itai Hayut, CEO of Scopio Labs. However, our offering only begins there. We have also been developing cutting edge AI models for various use cases in human medicine that are now in various stages of clinical validation. Because the biology is similar, we are able to adjust this AI infrastructure to veterinary samples. Our breakthrough diagnostic platform for veterinary medicine incorporates both AI and remote connectivity to drive the field forward. Veterinary diagnostics is changing rapidly, and were excited to be a part of it.

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Scopio Labs Enhances Digital Cytology Through The Launch Of Automated Imaging And Solutions For Veterinary Market - Pulse 2.0

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The Photograph and Premature come from two different traditions of black love in the movies – The Undefeated

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on The Photograph and Premature come from two different traditions of black love in the movies – The Undefeated

If youre looking for black romance onscreen, you first have to ask: which kind?

Two films released within a week of each other, The Photograph and Premature, exemplify two paths of black cinematic romance that have emerged since a mini golden age of onscreen black love in the late 90s and early 2000s.

Back then, it was impossible to miss the Black Love Brat Pack: mainstream, studio-backed offerings from Theodore Witcher (Love Jones), Gina Prince-Bythewood (Love & Basketball), Malcolm D. Lee (The Best Man), and Rick Famuyiwa (The Wood, Brown Sugar). These films formed a contemporary canon, and launched the careers of a set of actors who became synonymous with the genre, especially Sanaa Lathan, Nia Long, Taye Diggs, Morris Chestnut, Gabrielle Union, and Regina Hall. Their films became pop culture touchstones: endlessly referenced and rewatched, just like the A Different World reruns that used to dominate Nick at Nite.

(Want to launch a grenade at a house party? Try saying Love Jones wasnt actually a good movie, stand back, and watch the argumentative chaos follow.)

Offerings from the Black Love Brat Pack began to thin in the mid-2000s, before a mini-revival of sequels, along with Lees adaptation of the Steve Harvey dating advice book, Think Like a Man, reinvigorated the genre.

What filled the space left by those films? A lot of contemplative, experimental indies, and the web series put forth by Numa Perrier and Dennis Dortchs Black & Sexy TV, an outfit that produced and distributed Hello Cupid, The Number, and The Couple. They were an instrumental part of a black web series boom that also included Issa Raes The Misadventures of Awkward Black Girl.

In 2008, around the same time as Black & Sexy began its ascent, Barry Jenkins released Medicine for Melancholy, which starred Wyatt Cenac and Tracey Heggins as a San Francisco couple coming together against a backdrop of gentrification. Ava DuVernay premiered I Will Follow, a drama about a woman sorting out her life and relationships as she cares for a sick aunt, in 2011. Her star began to rise, especially when DuVernay became the first black woman to win the best director prize at the Sundance film festival for Middle of Nowhere, which focused on the life of a woman whose partner is incarcerated. Dee Rees feature debut, Pariah, came out in 2011, and Terence Nance followed with An Oversimplification of Her Beauty, a weird, heartfelt drama that combined animation and live action, in 2012.

Michael Block (LaKeith Stanfield, left) and Mae Morton (Issa Rae, right) in The Photograph, which was written and directed by Stella Meghie.

Emily Aragones/Universal Pictures

The Black Love Brat Pack dramas and comedies focused on the romantic lives of professional people and their romantic entanglements. It was a small circle. The directors would talk to each other, which is how Prince-Bythewood ended up casting Hall in Love & Basketball she saw her in The Best Man and called Lee. While the Black Love Brat Pack films were lighthearted and largely divorced from larger social issues, the indies often were not. They incorporated themes of displacement and mass incarceration and explorations of queer sexuality. Without the big promotional budgets that come with wide-release films, they often found their audiences through streaming services and word-of-mouth. What emerged felt new and different: a spate of filmmakers introducing work, often made with microscopic budgets, that thrived on creating atmospheres of connection and intimacy.

In The Photograph, her first turn as a romantic lead in a studio drama, Rae appeared to be pulling from both traditions. In her 2016 memoir, Rae wrote about her admiration for Prince-Bythewood and Love & Basketball and how it inspired her to write her own movie, called Judged Cover. She wrote to Prince-Bythewood to tell the director that she watched Love & Basketball daily for inspiration. Meanwhile, her co-star in The Photograph, LaKeith Stanfield, had emerged as a poster boy of the indie film set, thanks to turns in Short Term 12, Sorry to Bother You, and Get Out.

The Photograph is very much a millennial film that hearkens back to the glory days of the Black Love Brat Pack. Its about two normal black people, as Rae calls them: middle-class professionals living in New York. Theres no backdrop of poverty, or stop-and-frisk, or other forms of structural racism coloring the lives of Raes and Stanfields characters.

On Friday, IFC films releases Premature, a coming-of-age romance shot in 16mm that harkens back to films such as Shes Gotta Have It (1986), Just Another Girl on the I.R.T. (1992), Kids (1995), and Raising Victor Vargas (2002). The film, which won the Film Independent Spirit Award for Someone to Watch, will have a theatrical run in New York and Los Angeles, and is also available to stream. Set in gentrifying modern-day Harlem, playwright and poet Zora Howard, who co-wrote the movie, stars as Ayanna, a recent high school graduate in the summer before she starts life as a freshman at Bucknell. She falls for the slightly older Isaiah (Joshua Boone), a producer and composer, and who gently persists in pursuing her after meeting Ayanna during a pickup game at Rucker Park.

I enjoyed Premature enormously. Its a thoughtful portrait of what its like to exist in the space of early adulthood while experiencing an intoxicating first love. Howard, in her first feature performance, imbues Ayanna with a wild, hungry, sexuality that also can quickly turn bashful and insecure. She refuses to say much to Isaiah when he first expresses interest. He sits on a playground swing next to her and introduces himself, and Ayanna simply walks off without revealing her name. Then hes chasing after her down the street days later, as Ayanna hauls a bag of laundry back to the apartment she shares with her mother.

Joshua Boone (left) as Isaiah and Zora Howard (right) as Ayanna in Premature.

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Cinematographer Laura Valladeos choices feel rich and revelatory, especially in the sex scenes. This is fully Ayannas story, told from her point of view. She practically devours Isaiah when they finally get some time alone, and when he slows things down, she shrinks, chastened, and sits covering herself as Isaiah picks out a record to play.

Its a masterful portrayal of the appearance of confidence that comes with being 17, of being talented and smart and yet unaware of what you dont know. Ayanna, having witnessed her mothers disinterested approach to come-and-go suitors, realizes that she and Isaiah have something special, and she tries desperately to protect it, even as their age difference begins to present fissures. Shes got a lot in common with the titular character in Juno, and with Carey Mulligan in An Education, teenage characters known for their emotional precocity. The story crests with a pregnancy and an abortion. But the film never becomes an issue film. Premature is not really an abortion story, but one about a girl finding her voice, and learning to put herself first.

Whats frustrating, ultimately, when it comes to the way we consume black romance, is how much loveliness remains hidden by contrasts in distribution. Premature deserves as wide a release and as much attention as The Photograph, especially when a new, millennial Black Love Brat Pack has yet to emerge. Perhaps thats because these types of indies are where black love stories are headed. Wouldnt it be nice if studios took heed?

Soraya Nadia McDonald is the culture critic for The Undefeated. She writes about pop culture, fashion, the arts, and literature. She's based in Brooklyn.

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Zinc Sulfate Heptahydrate Market Increasing Demand with Leading Player, Comprehensive Analysis, Forecast 2026| China Bohigh, IRO Group, Noah…

§ February 21st, 2020 § Filed under Nano Medicine Comments Off on Zinc Sulfate Heptahydrate Market Increasing Demand with Leading Player, Comprehensive Analysis, Forecast 2026| China Bohigh, IRO Group, Noah…

Global Zinc Sulfate Heptahydrate Market Latest Research Report 2020

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The report has been curated after observing and studying various factors that determine regional growth such as economic, environmental, social, technological, and political status of the particular region. Analysts have studied the data of revenue, production, and manufacturers of each region. This section analyses region-wise revenue and volume for the forecast period of 2015 to 2026. These analyses will help the reader to understand the potential worth of investment in a particular region.

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Sunburn The morning read of what’s hot in Florida politics 2.20.20 – Florida Politics

§ February 20th, 2020 § Filed under Nano Medicine Comments Off on Sunburn The morning read of what’s hot in Florida politics 2.20.20 – Florida Politics

Six Democratic presidential hopefuls met on the debate stage in Las Vegas, but it was the newcomer, former New York Mayor Mike Bloomberg, who received the most attention, and none of it positive. Here are some key takeaways from the debate.

The $60 billion punching bag

Bloomberg was the object of scorn, ridicule and contempt. And that was just in the first five minutes of the debate.

With all candidates flashing heat, a measure of the urgency they feel to survive in what is becoming an increasingly bitter nomination fight, the attacks focused on Bloomberg were a clear measure of his perceived strength. He has spent more than $400 million so far on advertising that in turn has given him strong standing in state and national polls.

Sen. Bernie Sanders recalled Bloombergs support of stop-and-frisk policing targeting minorities. Sen. Elizabeth Warren recalled how Bloomberg had mocked women for being horse-faced and fat and compared him to Trump. Sen. Amy Klobuchar quipped that I dont think you look at Donald Trump and say I think we need someone richer in the White House. Former Vice President Joe Biden said Bloomberg condoned racist police practices, and Pete Buttigieg, the former mayor of South Bend, Indiana, said Bloomberg was trying to buy out the Democratic Party.

But his biggest struggle came when Warren hammered him over allegations of sexism and mistreatment of women in his company.

Bloomberg attempted to defend his record and deflect the attacks on him by turning them into attacks on President Donald Trump. And he effectively raised questions about whether Americans would embrace a socialist like Sanders.

But the glare was harsh, and the attacks landed with force.

Even if you are worth $60 billion it is hard to win a 5-on-1 fight.

Not the era of good feelings

For eight debates, the Democrats largely tiptoed around disagreements except for desultory disputes about health care policies. But on Wednesday night, everyone came with sharp elbows.

It was almost impossible to keep track of the fights. Buttigieg and Klobuchar tussled over experience and the Minnesota senator forgetting the name of Mexicos president. Buttigieg and Sanders argued about the Vermont senators big-ticket plans and refusal to release his full medical records. Warren clashed with Buttigieg and Klobuchar over their health care plans. And everyone piled onto Bloomberg.

The former New York mayor was the only candidate who didnt really go on the attack, other than the occasional swipe at the self-declared socialist Sanders.

In the end, that dynamic may again benefit Sanders, who leads in the polls and is watching his rivals spend most of their energy tearing each other down rather than targeting him.

Return of Warren the fighter

Warren rose to prominence in the Democratic field with a fighting spirit that defined the early months of her campaign. But her disappointing showings in Iowa and New Hampshire left her campaign struggling.

On Wednesday, she decided to get back into the fight.

She slammed Bloomberg that was no surprise as shes been an antagonist of billionaires playing in politics for years. But Warren also attacked Klobuchar, saying her health care plan was just a Post-it note. She accused Buttigieg of being in debt to his rich campaign supporters and having a health care plan that was just a PowerPoint designed by his consultants. She slammed fellow liberal Sanders, accusing him of letting his supporters trash anyone with a plan.

But it was her prosecutorial approach to Bloomberg over his companys treatment of women that stood out.

Whatever happens on Saturday, and beyond, Warren regained her fighting voice.

The generational divide

Buttigieg, who finished in the top two in Iowa and New Hampshire with Sanders, reserved some of his harshest criticism for Sanders, a man 40 years his elder.

He warned that Democrats could wake up after more than a dozen states vote on Super Tuesday on March 3 and have only Bloomberg and Sanders left on the ballot. He then quipped that the party may want to nominate someone who is actually a Democrat.

The crowd inside the Las Vegas casino hadnt yet finished chuckling and hooting when he continued by saying Sanders wants to burn this party down and Bloomberg wants to buy this party out.

Sanders, a senator from Vermont and avowed democratic socialist, responded by saying that Buttigiegs campaign has been too reliant on billionaire big donors, touching off another intense exchange.

Their back and forth continued through criticism of Sanders supporters who have frequently been accused of bullying behavior online. Sanders said he personally had denounced such behavior. This prompted Buttigieg to say he believed the senator but, What it is it about your campaign in particular that seems to be motivating this type of behavior?

On this night, Buttigieg had the most at stake, with Sanders standing in Nevada polls well ahead of the man who has run even with him in the first two contests.

But Sanders did nothing likely to undermine his standing as the leading candidate so far.

Does Klobentum continue?

The last debate was rocket fuel for Klobuchar. Her strong performance vaulted her to a third-place finish in New Hampshire and onto Nevada. But it may be hard for lightning to strike twice.

The Minnesota senator often got drowned out in the high-octane bickering Wednesday, or pulled down into the mud. At one point she pulled from her supply of ready quips, saying of Sanders and Bloomberg as they argued over capitalism that there is a boxing rematch in Vegas on Saturday and these guys should go down there.

The most damaging exchange was between Klobuchar and Buttigieg, who have tangled before. Asked about her embarrassing gaffe in forgetting the name of Mexicos president, she had to fend off Buttigieg, who claimed it disproved her argument that Washington has prepared her to be president. She also alternately scrapped with and aligned with Warren.

Are you calling me dumb? Klobuchar asked Buttigieg incredulously. Later, she added, I wish everyone was as perfect as you, Pete.

A little over a week ago in New Hampshire, Klobuchar clearly stood out. This time was much harder as everyone battled for survival.

Did Biden revise his campaign?

Another candidate in need of a big night to reverse perceptions that his campaign was struggling was Biden.

For a good portion of the debate, he receded. He joined in the attacks on Bloomberg, but largely avoided some of the more testy exchanges.

When Warren said that Biden was in the pocket of Republican Mitch McConnell, the Senate majority leader, Biden fought back. He also tried to return to his Middle Class Joe biography about his familys financial struggles.

He did not offer voters any new rationale for voting for him.

Bloomberg bombs in debate debut via POLITICO He rolled his eyes when Elizabeth Warren pressed him to release women at his company from non-disclosure agreements related to alleged mistreatment. He suggested he cant simply use TurboTax, like many Americans, to crunch his billions in order to speed up the release of his tax returns. He pouted when moderators didnt return to him on health care, muttering, What am I, chicken liver? Bloomberg spent the past 10 weeks flooding the airwaves with ads, racking up endorsements and climbing into contention ahead of his Super Tuesday debut. And in two hours Wednesday night, he risked losing those swift gains as he stumbled through his first nationally televised primary debate.He was rusty. He was testy. He was out of touch. And, for a candidate often shielded by the scripted one-liners of killer campaign advisers, he was on his own unable to hide his peevish demeanor and unable to portray himself, as his campaign has tried to do, as the clear choice to stop Bernie Sanders and beat Trump.

Loathing in Las Vegas: Amy and Petes resentment boils over viaElena Schneider of POLITICO Klobuchar made sure there would be no post-debate handshake with Pete Buttigieg. After a series of cutting exchanges during Wednesdays presidential debate, Klobuchar cut around Buttigieg without a glance in his direction as they stepped away from their neighboring podiums following Wednesdays Democratic showdown.

Pete Buttigieg and Amy Klobuchar are both hawking middle-of-the-road, tell-it-like-it-is personas.

The hostility building between the two Midwestern Democratsburst dramatically into the open in Nevada, as they clashed repeatedly on the debate stage and tried to slash the momentum out of each others campaigns. Klobuchar and Buttigieg have fought before over their experience and their political records in past debates but the feud took a deeply personal turn.

He Said, She Said colors in the presidential primary On the new episode of He Said, She Said, Michelle and I start with a couple of recaps: our current bets on PredictIt and our Valentines Day activities.

Moving on to politics, pollster Steve Vancore gives his predictions for Floridas Democratic presidential primary and talks about President Donald Trump at the Daytona 500. Then Vancore also breaks down our increasingly siloed lives. If he had to place a PredictIt bet, Vancore says Bernie Sanders is a buy and explains why Joe Biden would stay in the race through South Carolina and Super Tuesday.

Michelle and I debate the Democratic field and examine the flaws of a Sanders nomination.

Adam Goodman joins the pod to give a deep dive into the various paths the Democratic primary could take, drawing parallels from the current presidential race to the 2018 gubernatorial race between Ron DeSantis and Andrew Gillum. Goodman explains why he would want to see Bernie Sanders go head-to-head with Trump. I disagree.

We also talk about what a Bloomberg nomination could mean for the Democrats. Goodman says it will feed into Trumps class warfare narrative.

To subscribe and listen, visit Apple Podcasts, Google Play and Stitcher.


The House will be voting today to require parental consent for abortions and to strip the Florida Coalition Against Domestic Violence of their exclusive contract with the state.

Also, on todays Sunrise:

A federal appeals court in Atlanta rules against the state in a challenge over voting rights for former felons. The Governors office says theyll appeal.

President of New College, Donal OShea, comes to The Capitol at an existential moment. Hes trying to stop a bill that calls for his University to become a branch campus of Florida State University.

Crime survivors gather at The Capitol, calling for major changes in the criminal justice system. They want more rehabilitation and less incarceration to break the cycle of violence.

Vancore gives his take on Floridas presidential preference primary and the scandal at the Florida Coalition Against Domestic Violence.

The continuing adventures of Florida Man who has a severe drug problem.

To listen, click on the image below:


@NateSilver538: Average projected delegates through Super Tuesday: Sanders 608 (41% of delegates thru March 3) [Mike] Bloomberg 273 (18%) Biden 270 (18%) [Pete] Buttigieg 157 (10%) [Elizabeth] Warren 127 (8%) [Amy] Klobuchar 55 (4%).

@FlaFarmBureau: We hope @chucktodd asks @MikeBloomberg to describe how we should be hedging the corn futures market while calibrating a variable rate fertilizer spreader and planting crops on laser leveled fields with a GPS controlled auto-steer tractor. Well take notes.

@maxwelltani: After 2016, people said media needs to do a better job going to real America to cover the issues Americans actually care about. So its interesting to see media spend so much time discussing Bernie supporters online behavior, an issue primarily affecting media and political pros

@MattGaetz: Fifty years ago, a gay man or woman couldnt work in the intelligence community. Today President Trump is appointing an openly gay man to serve as Acting Director of National Intelligence. Congratulations, Ambassador

@TomLeeFL: E-Verify is either mandatory for all or its not mandatory.

@fineout: A Senate panel today spent less than 5 minutes to take up and vote out on a party-line vote a proposed constitutional amendment that would make it harder for future amendments to make ballot. This was the first time this proposed resolution had even been heard in Senate

@CarlosGSmith: No acknowledgment that his actions were homophobic or hurtful. No direct apology to the LGBTQ community or to his constituents. @ALJacquet clearly does not understand the gravity of his words or the harm they cause LGBTQ Floridians. Its sad, really.

@Daniel_Sweeney: Ah, its that time of the legislative session in Tallahassee when multiple bills on a subject havent quite gotten over the hill, so a new bill suddenly emerges and lawmakers all say, well, weve debated many of the parts of this bill, so its had a full hearing.

@ScottFist: Ive seen a lot of really, really good, really admirable, political journalists who, once they retire from journalism, explode with releasing their political opinions. Its kinda like holding in a fart for 40 years. And it just doesnt smell good.

Tweet, tweet:

@KarlEtters: Another week. Another body found in a car at a Tallahassee Walmart.

@DanTallahassee: UF alumni association is sending me emails. How did this happen? Perhaps its because the brazen admissions folks at UF still cant get over how I chose FSU the true Harvard of the South over UF because of its proximity to the Capitol and less pretentious student body

Tweet, tweet:


Nevada caucuses 2; Better Call Saul Season 5 premiers 3; Suits for Session 5; 10th Democratic presidential debate in Charleston 5; The Markup, a nonprofit newsroom covering technology, launches 5; South Carolina Primaries 9; Super Tuesday 12; Last day of 2020 Session (maybe) 22; Floridas presidential primary 26; No Time to Die premiers 46; Florida TaxWatch Spring Board Meeting begins 55; TaxWatch Principal Leadership Awards 56; Florida Chamber Summit on Prosperity and Economic Opportunity 85; Top Gun: Maverick premiers 127; Democratic National Convention in Milwaukee begins 144; Christopher Nolans Tenet premiers 148; 2020 Summer Olympics in Tokyo start 155; Florida primaries for 2020 state legislative/congressional races 180; Republican National Convention begins in Charlotte 186; First Presidential Debate in Indiana 222; First Vice Presidential debate at the University of Utah 230; Second Presidential Debate scheduled at the University of Michigan 238; Third presidential debate at Belmont 245; 2020 General Election 257.


Mike Pompeos Florida tour included undisclosed stop at The Villages, and the State Department wont say why via Steve Contorno of the Tampa Bay Times Secretary of State Pompeo managed to squeeze in an appearance in Bushnell last month. If Pompeo had a reason for stopping in this city of 3,100 on Jan. 23, he didnt reveal it during his brief remarks at the Sumter County Fairgrounds. After 30 minutes there, his motorcade pulled out of the parking lot and sped away. But, it turns out, he wasnt ready to leave Florida quite yet. From the fairgrounds, Pompeo took an unannounced side trip to The Villages. Although its still not clear why Pompeo ventured to The Villages, the trail of paperwork traced Pompeos movements that day to the doorstep of one of the wealthiest Republican donors in Central Florida: the Morse family.

Mike Pompeo made an unscheduled stop in a major GOP donor during his visit to The Villages.


Court: Florida cant bar felons from vote over fines, fees via Bobby Caina Calvan and Curt Anderson of The Associated Press A three-judge panel of the 11th U.S. Circuit Court of Appeals upheld a Tallahassee federal judges preliminary injunction that a state law implementing Amendment 4 amounted to an unfair poll tax that would disenfranchise many of the released felons. In its ruling, the circuit court said the financial requirement punishes those who cannot pay more harshly than those who can and does so by continuing to deny them access to the ballot box. The court added that previous U.S. Supreme Court rulings required it to apply heightened scrutiny in asking whether the requirement violates the Equal Protection Clause of the Fourteenth Amendment as applied to these plaintiffs.

Ron DeSantis bolsters deregulation office Gov. DeSantis penned an executive order in November directing that increased the power of the Office of Fiscal Accountability and Regulatory Reform, Matt Dixon of POLITICO Florida reports. The order called for the Office of Policy and Budget to designate a liaison to OFARR for each area of the budget. DeSantis spokesperson Helen Aguirre Ferr said this week that the memo was to ensure that there was designated personnel in each policy area to get a more thorough organizational review of state regulations.

DeSantis announces $4.8 million grant for ST engineering expansion, project now fully funded via Jim Little of the Pensacola News Journal The expansion project, which calls for building three more hangars and office space for ST Engineering, is expected to bring more than 1,300 jobs to the airport. ST Engineering opened its first maintenance, repair and overhaul, or MRO, hangar at the Pensacola Airport in June 2018. That hangar is expected to employ 400 people when operating at full capacity, putting the number of jobs at the entire facility at more than 1,700 people. At last count in January, ST Engineer had 163 employees at the airport. DeSantis said the ST Engineering expansion would have an impact on the economy of the entire region and would not have happened without many people coming together to support it.

Ron DeSantis announces a major job growth grant for Pensacola Airport.

DeSantis unveils housing loan program for military, veterans DeSantis announced the Salute Our Soldiers Military Loan Program (SOS) for veterans and active-duty military personnel throughout the state. The announcement followed a roundtable to discuss ongoing issues and initiatives that involve Floridas military and veteran population. Joining the Governor were Florida Department of Veterans Affairs (FDVA) Executive Director Danny Burgess and Florida Housing Finance Corporation (Florida Housing) Executive Director Trey Price. Florida Housing will set aside funds to assist over 1,000 veterans and active-duty military members by making the homebuying process easier and more affordable, DeSantis said. More veterans calling Florida home is a great thing for all involved.

Ron DeSantis also unveils a housing loan program to benefit Florida service members and veterans.

Jos Oliva earns praise for Nurse Practitioner of the Day pick House Speaker Olivaselected Donna Bixler for Nurse Practitioner of the Day. Bixler is a family nurse practitioner affiliated with the Internal Medicine division at Southern Medical Group in Tallahassee, where she has practiced since 1998. Oliva earned praise from Floridians Unite for Health Care, both for his continued recognition of APRNs and his support of a bill (HB 607) that would grant independent practice rights to APRNs and physician assistants. The bill has cleared two committees and is awaiting a hearing in the House Health and Human Services Committee, its final stop before the chamber floor.

Congratulations to Donna Bixler, named Nurse Practitioner of the Day.

County RECs back strong E-Verify bill The Republican Party of Florida already passed a resolution in favor of E-Verify requirements for all businesses. Additionally, 16 county Republican Executive Committees have passed measures of their own. Those include Bradford; Duval; Hamilton; Highlands; Indian River; Lake; Leon; Levy; Manatee; Marion; Okeechobee; Palm Beach; Saint Lucie; Sarasota; Volusia; and Walton counties. Floridas economy continues to grow under Republican leadership, and using E-Verify, we will only expand jobs and opportunities for legal workers in our state, said RPOF Chair Joe Gruters. After all, we live in a nation of laws and illegal immigration undermines those laws, threatens public safety in our state, and undercuts wages for Florida workers. It is only right to require employers to follow the rule of law and to ensure that the workers they are hiring are eligible and, in our country, legally.

Amid pay scandal, Floridas domestic violence nonprofit loses support via Mary Ellen Klas and Samantha Gross of the Tampa Bay Times The Florida House took the first step toward severing the special arrangement the state has with the Florida Coalition Against Domestic Violence and advanced a bill to require the agency to face competition. It is only the beginning of the changes ahead for the agency under fire for paying former CEO Tiffany Carr more than $7.5 million over three years as domestic violence victims across the state were denied services. Documents show that Carr was allowed to cash-in more than $5 million of paid time off at the agency that is primarily funded with state and federal taxpayer dollars. The bills are expected to be approved and signed by the Governor before the Session ends.

New College Prez, Sarasota Democrats urge no on university merger plan via Sarah Mueller of Florida Politics Members of the Sarasota County legislative delegation joined New College President OShea in speaking out against the proposal at The Capitol. Republican Sen. Gruters set up the press conference. But Republican members of the delegation were a no-show. I did have some conversations, but at the end of the day, it really was just a mix-up in time, and since everybody was already scheduled, I couldnt make it, and so we just allowed it to continue on, he said. Once that message got back, thats why there was confusion, but it was inadvertent. All the delegation, except for Senate President Bill Galvano, have written a local op-ed article opposing the bill.

Manufactured home bill gets owner, industry backing via Florida Politics A joint announcement from the Federation of Manufactured Homeowners of Florida (FMO) and the Florida Manufactured Housing Association comes after the bills HB 1339 by Rep. Clay Yarborough and SB 998 by Sen. Travis Hutson were altered to add protections for tenants privacy, clarify HOA governance requirements and increase the amount of housing available. Updating to the 40-year-old manufactured home statutes has been a longtime priority for both parties, though they havent always seen eye-to-eye on what those updates should include. Thats led to dead bills in Sessions past.

Pro athlete, other crime victims come to Capitol for annual survivors speak rally via Tori Lynn Schneider of the Tallahassee Democrat Stedman Bailey, a Miramar native, was drafted into the NFL by the St. Louis Rams in 2013. His career was cut short just two years later. I was in the car with my cousin, his 10-year-old son, and 6-year-old daughter and my best friend when our car was shot at over 30 times, Bailey said Wednesday. Two bullets struck me in my head, and my cousin was also shot. Bailey and hundreds of other crime survivors visited the Florida Capitol for the third annual Survivors Speak rally, organized by Crime Survivors for Safety and Justice (CSSJ). Aswad Thomas, its managing director, announced his groups two biggest priorities: Housing and job protections for survivors of crime and criminal justice reform.


House moves forward with tax cut package, would allow tourism tax dollars for water projects via Jim Turner of the News Service of Florida The Ways & Means Committee approved the package (PCB WMC 20-01), which features sales-tax breaks before hurricane season and the new school year, while trimming taxes on commercial leases and cellphones and other communications services. It also calls for increasing a refund on aviation-fuel taxes, eliminating an unused pool of money for professional sports stadiums, expanding a tax-distribution requirement about charter schools, and adding water infrastructure projects to the list of allowed uses for local tourist- development dollars. The proposal is expected to see some changes before the House negotiates with the Senate on a final package.

Tourism industry slams House tax-cut package The tourism industry is vehemently opposed to a provision in the House tax-cut package that would allow local governments to use tourism tax money on local water projects, Matt Dixon of POLITICO Florida reports. After the plan was unveiled, members of the tourism lobby spoke out against the plan, arguing the tax collections are solely for tourism marketing ventures. Republican Rep. Brian Avila, who chairs the committee behind the bill, said clean water would help attract tourism. In the long run, I am 100 percent confident that our vision for the tourist development tax will ultimately have a positive impact on the tourism industry, he said.

House offers tax break to utilities for solar energy via Mary Ellen Klas of the Miami Herald Quietly tucked into the Houses package of tax breaks is a measure that will let Florida Power & Light and other utilities save millions by delaying the date on which it starts paying taxes on dozens of solar energy plants under construction across the state. The issue didnt come up during the tax workshop, but House Speaker Oliva asked for the budget impact of the proposal to be assessed by state economists in December. The provision was added to the bill, and the House Ways and Means Committee approved the language.

Senate President comes out in support of university merger proposal via Florida Politics The merger is one opportunity that could exist that needs to be discussed, he said.Galvano said he met with New College President Donal OShea who was in Tallahassee to lobby lawmakers against voting for the bill. The Senate President says OShea admitted to struggling to boost enrollment.I shared exactly what I thought were some concerns, he said. And he said Look, its been hard for us. Weve had the performance funding and we werent meeting the metrics. Our population was not hitting on some of these points that other universities do. So that put them behind fiscally. Also enrollment has been a challenge for them.

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Sunburn The morning read of what's hot in Florida politics 2.20.20 - Florida Politics

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